ORTHOLOGY: K04519
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Entry
K04519 KO
Name
IL1B
Definition
interleukin 1 beta
Pathway
ko01523
Antifolate resistance
ko04010
MAPK signaling pathway
ko04060
Cytokine-cytokine receptor interaction
ko04064
NF-kappa B signaling pathway
ko04217
Necroptosis
ko04380
Osteoclast differentiation
ko04620
Toll-like receptor signaling pathway
ko04621
NOD-like receptor signaling pathway
ko04623
Cytosolic DNA-sensing pathway
ko04625
C-type lectin receptor signaling pathway
ko04640
Hematopoietic cell lineage
ko04657
IL-17 signaling pathway
ko04659
Th17 cell differentiation
ko04668
TNF signaling pathway
ko04750
Inflammatory mediator regulation of TRP channels
ko04932
Non-alcoholic fatty liver disease
ko04933
AGE-RAGE signaling pathway in diabetic complications
ko04940
Type I diabetes mellitus
ko05010
Alzheimer disease
ko05020
Prion disease
ko05022
Pathways of neurodegeneration - multiple diseases
ko05130
Pathogenic Escherichia coli infection
ko05131
Shigellosis
ko05132
Salmonella infection
ko05133
Pertussis
ko05134
Legionellosis
ko05135
Yersinia infection
ko05140
Leishmaniasis
ko05142
Chagas disease
ko05143
African trypanosomiasis
ko05144
Malaria
ko05146
Amoebiasis
ko05152
Tuberculosis
ko05162
Measles
ko05163
Human cytomegalovirus infection
ko05164
Influenza A
ko05168
Herpes simplex virus 1 infection
ko05171
Coronavirus disease - COVID-19
ko05321
Inflammatory bowel disease
ko05323
Rheumatoid arthritis
ko05332
Graft-versus-host disease
ko05418
Fluid shear stress and atherosclerosis
Disease
H01492
Systemic sclerosis
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K04519 IL1B; interleukin 1 beta
04064 NF-kappa B signaling pathway
K04519 IL1B; interleukin 1 beta
04668 TNF signaling pathway
K04519 IL1B; interleukin 1 beta
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
K04519 IL1B; interleukin 1 beta
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
K04519 IL1B; interleukin 1 beta
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
K04519 IL1B; interleukin 1 beta
04620 Toll-like receptor signaling pathway
K04519 IL1B; interleukin 1 beta
04621 NOD-like receptor signaling pathway
K04519 IL1B; interleukin 1 beta
04623 Cytosolic DNA-sensing pathway
K04519 IL1B; interleukin 1 beta
04625 C-type lectin receptor signaling pathway
K04519 IL1B; interleukin 1 beta
04659 Th17 cell differentiation
K04519 IL1B; interleukin 1 beta
04657 IL-17 signaling pathway
K04519 IL1B; interleukin 1 beta
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
K04519 IL1B; interleukin 1 beta
09158 Development and regeneration
04380 Osteoclast differentiation
K04519 IL1B; interleukin 1 beta
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
K04519 IL1B; interleukin 1 beta
05164 Influenza A
K04519 IL1B; interleukin 1 beta
05162 Measles
K04519 IL1B; interleukin 1 beta
05168 Herpes simplex virus 1 infection
K04519 IL1B; interleukin 1 beta
05163 Human cytomegalovirus infection
K04519 IL1B; interleukin 1 beta
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
K04519 IL1B; interleukin 1 beta
05132 Salmonella infection
K04519 IL1B; interleukin 1 beta
05131 Shigellosis
K04519 IL1B; interleukin 1 beta
05135 Yersinia infection
K04519 IL1B; interleukin 1 beta
05133 Pertussis
K04519 IL1B; interleukin 1 beta
05134 Legionellosis
K04519 IL1B; interleukin 1 beta
05152 Tuberculosis
K04519 IL1B; interleukin 1 beta
09174 Infectious disease: parasitic
05146 Amoebiasis
K04519 IL1B; interleukin 1 beta
05144 Malaria
K04519 IL1B; interleukin 1 beta
05140 Leishmaniasis
K04519 IL1B; interleukin 1 beta
05142 Chagas disease
K04519 IL1B; interleukin 1 beta
05143 African trypanosomiasis
K04519 IL1B; interleukin 1 beta
09163 Immune disease
05323 Rheumatoid arthritis
K04519 IL1B; interleukin 1 beta
05321 Inflammatory bowel disease
K04519 IL1B; interleukin 1 beta
05332 Graft-versus-host disease
K04519 IL1B; interleukin 1 beta
09164 Neurodegenerative disease
05010 Alzheimer disease
K04519 IL1B; interleukin 1 beta
05020 Prion disease
K04519 IL1B; interleukin 1 beta
05022 Pathways of neurodegeneration - multiple diseases
K04519 IL1B; interleukin 1 beta
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
K04519 IL1B; interleukin 1 beta
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
K04519 IL1B; interleukin 1 beta
04932 Non-alcoholic fatty liver disease
K04519 IL1B; interleukin 1 beta
04933 AGE-RAGE signaling pathway in diabetic complications
K04519 IL1B; interleukin 1 beta
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
K04519 IL1B; interleukin 1 beta
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors
K04519 IL1B; interleukin 1 beta
00536 Glycosaminoglycan binding proteins
K04519 IL1B; interleukin 1 beta
Cytokines and growth factors [BR:
ko04052
]
Cytokines
Interleukins
K04519 IL1B; interleukin 1 beta
Glycosaminoglycan binding proteins [BR:
ko00536
]
Heparan sulfate / Heparin
Cytokines
K04519 IL1B; interleukin 1 beta
BRITE hierarchy
Other DBs
GO:
0005149
Genes
HSA:
3553
(IL1B)
PTR:
450200
(IL1B)
PPS:
100993613
(IL1B)
GGO:
101130571
(IL1B)
PON:
100454379
(IL1B)
NLE:
100587357
(IL1B)
MCC:
704701
(IL1B)
MCF:
102119749
(IL1B)
CSAB:
103241278
(IL1B)
RRO:
104672547
(IL1B)
RBB:
108541809
(IL1B)
CJC:
100406769
(IL1B)
SBQ:
101033664
(IL1B)
MMU:
16176
(Il1b)
MCAL:
110290100
(Il1b)
MPAH:
110319321
(Il1b)
RNO:
24494
(Il1b)
MUN:
110551400
(Il1b)
CGE:
100775079
(Il1b)
NGI:
103739899
(Il1b)
HGL:
101704309
(Il1b)
CCAN:
109701168
(Il1b)
OCU:
100008990
(IL1B)
TUP:
102475138
(IL1B)
CFA:
403974
(IL1B)
VVP:
112916797
(IL1B)
AML:
100480874
(IL1B)
UMR:
103671495
(IL1B)
UAH:
113242506
(IL1B)
ORO:
101383005
(IL1B)
ELK:
111158456
FCA:
768274
(IL1B)
PTG:
102951272
(IL1B)
PPAD:
109264508
(IL1B)
AJU:
106976013
(IL1B)
BTA:
281251
(IL1B)
BOM:
102282890
(IL1B)
BIU:
109566133
(IL1B)
BBUB:
102396262
(IL1B)
CHX:
100860816
(IL1B)
OAS:
443539
(IL1B)
SSC:
396565
(IL1B2)
397122
(IL1B)
CFR:
102521979
(IL1B)
CDK:
105093155
(IL1B)
BACU:
103008438
(IL1B)
LVE:
103090784
(IL1B)
OOR:
101284892
(IL1B)
DLE:
111187492
(IL1B)
PCAD:
102994188
(IL1B)
ECB:
100034237
(IL1B)
100052414
(IL1B)
111768185
EPZ:
103544835
(IL1B)
EAI:
106838557
(IL1B)
MYB:
102251576
(IL1B)
MYD:
102769803
(IL1B)
MNA:
107528631
(IL1B)
HAI:
109393524
(IL1B)
DRO:
112302944
(IL1B)
PALE:
102893238
(IL1B)
RAY:
107514900
(IL1B)
MJV:
108393034
(IL1B)
LAV:
100674746
(IL1B)
TMU:
101359415
(IL1B)
MDO:
100026024
(IL1B)
SHR:
100922350
(IL1B)
PCW:
110192539
(IL1B)
OAA:
103165286
(IL1B)
GGA:
395196
(IL1B)
MGP:
100034741
(IL1RN)
CJO:
107323637
NMEL:
110387108
TGU:
100227014
(IL1B)
LSR:
110478285
(IL1B)
SCAN:
103822662
(IL1B)
GFR:
102041770
(IL1B)
FAB:
101819115
(IL1B)
PHI:
102108659
(IL1B)
PMAJ:
107213896
CCAE:
111938925
CCW:
104683159
ETL:
114070272
(IL1B)
FPG:
101924267
FCH:
102050776
CLV:
102090585
(IL1B)
EGZ:
104132895
(IL1RN)
NNI:
104022599
ACUN:
113488139
PADL:
103912923
ASN:
102369595
112547978
AMJ:
102570262
(IL1B)
102575353
PSS:
102448244
CMY:
102933972
102936298
CPIC:
101943587
(IL1B)
101949861
PVT:
110072197
(IL1B)
PBI:
103055254
(IL1B)
PMUR:
107283245
(IL1B)
TSR:
106544675
PMUA:
114603303
(IL1B)
GJA:
107118765
XLA:
108711577
(il1b.L)
108711578
108712739
373606
(il1b.S)
XTR:
100487038
(il1b)
116409784
NPR:
108785587
108785600
DRE:
405770
(il1b)
SRX:
107706800
107735843
SANH:
107658569
107682454
SGH:
107554524
107581079
107589025
CCAR:
109062938
109062992
109062994
109097442
IPU:
100304696
(il1b)
100304697
(il1b)
PHYP:
113544737
AMEX:
103026214
111194997
EEE:
113584063
TRU:
101080001
(il1b)
LCO:
104923462
NCC:
104948030
104955090
(il1b)
MZE:
101472948
101473431
101481848
101485031
ONL:
100693282
100707066
100707443
OLA:
101169209
XMA:
102231459
106700093
111610322
XCO:
114149066
114153988
114155120
PRET:
103470686
103473214
CVG:
107099154
107099476
NFU:
107386182
KMR:
108242738
(il1b)
ALIM:
106510763
(il1b)
106522184
AOCE:
111580399
111583887
CSEM:
103389940
103396898
103397875
POV:
109626174
109641260
LCF:
108878374
108895307
SDU:
111227981
111227984
111239668
SLAL:
111659489
111660942
111660964
111666074
HCQ:
109513432
BPEC:
110166705
110172087
(il1b)
MALB:
109951327
109953309
SASA:
100136449
106562915
(IL-1b3)
106570815
OTW:
112219797
112230772
112248882
SALP:
111963800
111974578
112071295
ELS:
105007339
105009489
SFM:
108932396
108940319
114909774
PKI:
111848567
111851454
LCM:
102364535
CMK:
103187802
» show all
Taxonomy
UniProt
Reference
PMID:
6083565
Authors
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA
Title
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
Journal
Proc Natl Acad Sci U S A 81:7907-11 (1984)
DOI:
10.1073/pnas.81.24.7907
Sequence
[hsa:
3553
]
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