KEGG   ORTHOLOGY: K00804
Entry
K00804                      KO                                     
Symbol
GGPS1
Name
geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Pathway
map00900  Terpenoid backbone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00367  C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
    2.5.1.29  geranylgeranyl diphosphate synthase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
Prenyltransferases [BR:ko01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
Other DBs
RN: R01658 R02003 R02061
COG: COG0142
GO: 0004161 0004337 0004311
Genes
HSA: 9453(GGPS1)
PTR: 100610192(GGPS1)
PPS: 100978959(GGPS1)
GGO: 101138399(GGPS1)
PON: 100444405(GGPS1)
NLE: 100589624(GGPS1)
MCC: 100425248(GGPS1)
MCF: 102115535(GGPS1)
CSAB: 103230796(GGPS1)
CATY: 105574886(GGPS1)
PANU: 101022877(GGPS1)
TGE: 112609106(GGPS1)
RRO: 104679169(GGPS1)
RBB: 108522207(GGPS1)
TFN: 117076615(GGPS1)
PTEH: 111545248(GGPS1)
CJC: 100411975(GGPS1)
SBQ: 101030657(GGPS1)
CSYR: 103252002(GGPS1)
MMUR: 105856482(GGPS1)
OGA: 100965550(GGPS1)
MMU: 14593(Ggps1)
MCAL: 110308036(Ggps1)
MPAH: 110333828(Ggps1)
RNO: 291211(Ggps1)
MUN: 110558130(Ggps1)
CGE: 100767405(Ggps1)
PLEU: 114685259(Ggps1)
NGI: 103745123(Ggps1)
HGL: 101698516(Ggps1)
CPOC: 100720358(Ggps1)
CCAN: 109692621(Ggps1)
DORD: 105984480(Ggps1)
DSP: 122113256(Ggps1)
NCAR: 124962307
OCU: 100340259(GGPS1)
TUP: 102477912 102496659(GGPS1)
CFA: 479198(GGPS1)
VVP: 112917731 112927367(GGPS1)
VLG: 121479354 121488127(GGPS1)
AML: 100473588(GGPS1)
UMR: 103661894(GGPS1)
UAH: 113259002(GGPS1)
UAR: 123782948(GGPS1)
ELK: 111160525
LLV: 125084303
MPUF: 101685984(GGPS1)
ORO: 101370952(GGPS1)
EJU: 114210231(GGPS1)
ZCA: 113920002(GGPS1)
MLX: 118012932(GGPS1)
FCA: 101082438(GGPS1)
PYU: 121023255(GGPS1)
PBG: 122492716(GGPS1)
PTG: 102952368(GGPS1)
PPAD: 109248883(GGPS1)
AJU: 106982555(GGPS1)
HHV: 120241829(GGPS1)
BTA: 780882(GGPS1)
BOM: 102280246(GGPS1)
BIU: 109553875(GGPS1)
BBUB: 102402997(GGPS1)
CHX: 102169552(GGPS1)
OAS: 101114414(GGPS1)
ODA: 120860497 120865422(GGPS1)
CCAD: 122446621(GGPS1)
SSC: 100739526(GGPS1)
CFR: 102503638(GGPS1)
CBAI: 105075106(GGPS1)
CDK: 105088831(GGPS1) 116149599
VPC: 102544907(GGPS1)
BACU: 103017222(GGPS1)
LVE: 103083669(GGPS1)
OOR: 101270381(GGPS1) 101270983
DLE: 111163940(GGPS1) 111165604
PCAD: 102979416(GGPS1)
PSIU: 116741480(GGPS1) 116748054
ECB: 100050954(GGPS1)
EPZ: 103547684(GGPS1)
EAI: 106834703(GGPS1)
MYB: 102260376(GGPS1)
MYD: 102771057(GGPS1)
MMYO: 118678828(GGPS1)
MLF: 102420834(GGPS1)
MNA: 107527182(GGPS1)
PKL: 118727684(GGPS1)
HAI: 109387736(GGPS1)
DRO: 112306046(GGPS1)
SHON: 118980665(GGPS1)
AJM: 119065824(GGPS1)
PDIC: 114512297(GGPS1)
PHAS: 123805529(GGPS1)
MMF: 118640560(GGPS1)
RFQ: 117018644(GGPS1)
PALE: 102888929(GGPS1)
PGIG: 120592554(GGPS1)
PVP: 105302717(GGPS1) 105310631
RAY: 107520046(GGPS1)
MJV: 108408921(GGPS1)
TOD: 119244586(GGPS1)
SARA: 101544477(GGPS1)
LAV: 100663324(GGPS1)
TMU: 101358569
DNM: 101440402(GGPS1)
MDO: 100021237(GGPS1)
GAS: 123243607(GGPS1)
SHR: 100918636(GGPS1)
PCW: 110217850(GGPS1)
OAA: 100081573(GGPS1)
GGA: 427092(GGPS1)
PCOC: 116228277(GGPS1)
MGP: 100551404(GGPS1)
CJO: 107311374(GGPS1)
NMEL: 110396189(GGPS1)
APLA: 101801532(GGPS1)
ACYG: 106048792(GGPS1)
AFUL: 116487298(GGPS1)
TGU: 100232753(GGPS1)
LSR: 110468869(GGPS1)
SCAN: 103818518(GGPS1)
PMOA: 120501116(GGPS1)
OTC: 121340911(GGPS1)
PRUF: 121363279(GGPS1)
GFR: 102035974(GGPS1)
FAB: 101814017(GGPS1)
PHI: 102113480(GGPS1)
PMAJ: 107201642(GGPS1)
CCAE: 111926854(GGPS1)
CCW: 104684288(GGPS1)
ETL: 114066551(GGPS1)
ZAB: 102067478(GGPS1)
FPG: 101911343(GGPS1)
FCH: 102045849(GGPS1)
CLV: 102094057(GGPS1)
EGZ: 104131017(GGPS1)
NNI: 104019872(GGPS1)
ACUN: 113478236(GGPS1)
TALA: 104365819(GGPS1)
PADL: 103921234(GGPS1)
ACHC: 115349740(GGPS1)
AAM: 106486810(GGPS1)
AROW: 112964538(GGPS1)
NPD: 112951975(GGPS1)
DNE: 112988985(GGPS1)
ASN: 102373119(GGPS1)
AMJ: 102571306(GGPS1)
CPOO: 109319969(GGPS1)
GGN: 109304707(GGPS1)
PSS: 102457955(GGPS1)
CMY: 102935186(GGPS1)
CPIC: 101934501(GGPS1)
TST: 117874694(GGPS1)
CABI: 116826424(GGPS1)
MRV: 120401461(GGPS1)
ACS: 100565156(ggps1)
PVT: 110075618(GGPS1)
SUND: 121923111(GGPS1)
PBI: 103064915(GGPS1)
PMUR: 107288311(GGPS1)
TSR: 106538178(GGPS1)
PGUT: 117656876(GGPS1)
VKO: 123018272(GGPS1)
ZVI: 118081869(GGPS1)
GJA: 107117724(GGPS1)
XLA: 100049104(ggps1.L) 108717904(ggps1.S)
XTR: 549876(ggps1)
NPR: 108799798(GGPS1)
RTEM: 120937470(GGPS1)
BBUF: 120998597(GGPS1)
BGAR: 122934720(GGPS1)
DRE: 336798(ggps1)
SANH: 107667013(ggps1) 107691209
SGH: 107569429(ggps1)
CCAR: 109105124(ggps1) 109111450
PPRM: 120461103(ggps1)
MAMB: 125276470(ggps1)
IPU: 108263030(ggps1)
PHYP: 113541961(ggps1)
SMEO: 124378537(ggps1)
TFD: 113655313(ggps1)
AMEX: 103030213(ggps1)
EEE: 113577748(ggps1)
LCO: 104934549(ggps1)
NCC: 104960300(ggps1)
CGOB: 115020424(ggps1)
ELY: 117247888(ggps1)
PLEP: 121954527(ggps1)
PFLV: 114571628(ggps1)
GAT: 120820348(ggps1)
PPUG: 119214535(ggps1)
MSAM: 119881840 119917141(ggps1)
CUD: 121510884(ggps1)
MZE: 101477767(ggps1)
ONL: 100693505(ggps1)
OAU: 116318607(ggps1)
OLA: 101169557(ggps1)
OML: 112161432(ggps1)
XMA: 102233815(ggps1)
XCO: 114137543(ggps1)
XHE: 116712634(ggps1)
PRET: 103477262(ggps1)
PFOR: 103137663(ggps1)
PLAI: 106949765(ggps1)
PMEI: 106930330(ggps1)
GAF: 122842962(ggps1)
CVG: 107087813(ggps1)
CTUL: 119782933(ggps1)
GMU: 124859565(ggps1)
NFU: 107375433(ggps1)
KMR: 108240652(ggps1)
ALIM: 106515876(ggps1)
NWH: 119411202(ggps1)
AOCE: 111573732(ggps1)
CSEM: 103387619(ggps1)
POV: 109642027(ggps1)
SSEN: 122782293(ggps1)
HHIP: 117775098(ggps1)
LCF: 108885800(ggps1)
SDU: 111220747(ggps1)
SLAL: 111659017(ggps1)
XGL: 120796249(ggps1)
HCQ: 109516188(ggps1)
BPEC: 110157161(ggps1)
MALB: 109962000(ggps1)
SASA: 100196754(ggps1)
OTW: 112237454(ggps1)
OMY: 110491209(ggps1)
OGO: 124048034(ggps1)
SALP: 112071950(ggps1)
SNH: 120046042(ggps1)
ELS: 105006090(ggps1)
SFM: 108933566(ggps1)
PKI: 111856365(ggps1)
AANG: 118218180(ggps1)
LOC: 102691303(ggps1)
PSPA: 121317205(ggps1)
ARUT: 117410901(ggps1)
LCM: 102358313(GGPS1)
CMK: 103178877(ggps1)
RTP: 109918358(ggps1)
BFO: 118419908
BBEL: 109470760
SPU: 575576
APLC: 110984925
SKO: 100371847
DME: Dmel_CG8593(qm)
DER: 6544432
DSE: 6611130
DSI: Dsimw501_GD14008(Dsim_GD14008)
DAN: 6507315
DSR: 110190817
DPE: 6602963
DMN: 108152067
DWI: 6639270
DGR: 6557470
DAZ: 108613653
DNV: 108651419
DHE: 111601038
DVI: 6622193
CCAT: 101454145
BOD: 106625442
MDE: 101901793
SCAC: 106089348
LCQ: 111688489
ACOZ: 120948362
AARA: 120908754
CPII: 120415744
CNS: 116351241
AME: 727189
ACER: 107998508
ALAB: 122710574
BIM: 100741327
BBIF: 117206461
BVK: 117237044
BVAN: 117160546
BTER: 100646723
BPYO: 122569731
CCAL: 108630853
OBB: 114878586
MGEN: 117218283
NMEA: 116426460
PBAR: 105433240
HST: 105180575
DQU: 106748661
LHU: 105673230
PGC: 109860942
PCF: 106784845
PFUC: 122521262
VPS: 122627081
CSOL: 105368212
TPRE: 106654395
MDL: 103570822
CGLO: 123265134
FAS: 105266588
AGIF: 122850027
CCIN: 107264535
TCA: 660091
DPA: 109541376
SOY: 115881323
ATD: 109595752
AGB: 108911309
LDC: 111511442
NVL: 108564043
APLN: 108741175
OTU: 111428345
BMOR: 101737879
BMAN: 114245250
MSEX: 115440663
PMAC: 106717826
PPOT: 106103796
PXU: 106116008
HAW: 110383989
TNL: 113500426
SLIU: 111355525
OFU: 114352593
PXY: 105388892
API: 100161650
AGS: 114126189
RMD: 113552148
BTAB: 109034594
DCI: 103524522
CLEC: 106667088
HHAL: 106681236
NLU: 111047526
FOC: 113207794
ZNE: 110836650
CSEC: 111870185
DMK: 116932753
HAME: 121864206
PCLA: 123774356
PTRU: 123519526
HAZT: 108682461
EAF: 111705842
LSM: 121115157
DSV: 119436218
RSAN: 119404089
RMP: 119187815
VDE: 111243127
VJA: 111268545
TUT: 107363541
DPTE: 113790825
DFR: 124496698
CSCU: 111631219
PTEP: 107441872
SDM: 118205166
PCAN: 112575826
HRJ: 124275076
CRG: 105331834
MYI: 110450576
PMAX: 117325439
MMER: 123562314
OBI: 106872435
OSN: 115223454
EGL: EGR_03356
NVE: 5504395
EPA: 110236964
ATEN: 116295355
ADF: 107329885
AMIL: 114965437
PDAM: 113666942
SPIS: 111341123
AQU: 100640281
SCE: YPL069C(BTS1)
SEUB: DI49_5391
ERC: Ecym_1170
KMX: KLMA_10752(BTS1)
NCS: NCAS_0C02140(NCAS0C02140)
NDI: NDAI_0E02850(NDAI0E02850)
TPF: TPHA_0I01940(TPHA0I01940)
TBL: TBLA_0A00600(TBLA0A00600)
TDL: TDEL_0B03100(TDEL0B03100)
KAF: KAFR_0E00960(KAFR0E00960)
KNG: KNAG_0A02000(KNAG0A02000)
PIC: PICST_46658(BTS1)
CAL: CAALFM_C503620WA(BTS1)
NCR: NCU01427(al-3)
NTE: NEUTE1DRAFT115818(NEUTE1DRAFT_115818)
SMP: SMAC_06570(putative al3)
SSCK: SPSK_05240
CMT: CCM_03697
MBE: MBM_04689
ANG: ANI_1_1118034(An03g02060) ANI_1_2028074(An08g06160) ANI_1_558054(An06g02090) ANI_1_992034(An03g00860)
ACHE: ACHE_30428A(BTS1)
APUU: APUU_11371S(BTS1_1) APUU_11665A(BTS1_2)
ABE: ARB_03622
TVE: TRV_03235
CNE: CNI00090
CNB: CNBH0100
TASA: A1Q1_04001
ABP: AGABI1DRAFT112964(AGABI1DRAFT_112964)
ABV: AGABI2DRAFT192934(AGABI2DRAFT_192934)
MGL: MGL_3268
MRT: MRET_2425
DDI: DDB_G0293588(ggps1)
DFA: DFA_03765(ggps1)
FCY: FRACYDRAFT_287526(GGPPS)
TPS: THAPSDRAFT_264430(GGPS3)
SPAR: SPRG_06894
 » show all
Reference
PMID:7665600
  Authors
Jiang Y, Proteau P, Poulter D, Ferro-Novick S
  Title
BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae.
  Journal
J Biol Chem 270:21793-9 (1995)
DOI:10.1074/jbc.270.37.21793
  Sequence
[sce:YPL069C]
Reference
  Authors
Kainou T, Kawamura K, Tanaka K, Matsuda H, Kawamukai M
  Title
Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.
  Journal
Biochim Biophys Acta 1437:333-40 (1999)
DOI:10.1016/S1388-1981(99)00028-1
  Sequence
[hsa:9453]
Reference
  Authors
Vandermoten S, Haubruge E, Cusson M
  Title
New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition.
  Journal
Cell Mol Life Sci 66:3685-95 (2009)
DOI:10.1007/s00018-009-0100-9
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