KEGG   PATHWAY: achc05132
Entry
achc05132                   Pathway                                
Name
Salmonella infection - Aquila chrysaetos chrysaetos (golden eagle)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
achc05132  Salmonella infection
achc05132

Organism
Aquila chrysaetos chrysaetos (golden eagle) [GN:achc]
Gene
115341913  PODXL; podocalyxin [KO:K06817]
115349175  PTPRC; receptor-type tyrosine-protein phosphatase C isoform X2 [KO:K06478] [EC:3.1.3.48]
115339064  RAB5A; ras-related protein Rab-5A [KO:K07887]
115350885  RAB5B; ras-related protein Rab-5B [KO:K07888]
115344277  RAB5C; ras-related protein Rab-5C [KO:K07889]
115336743  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
115353888  RAB7A; ras-related protein Rab-7a [KO:K07897]
115335071  RAB7B; ras-related protein Rab-7b [KO:K07898]
115344280  PLEKHM1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
115344500  VPS11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
115338089  VPS16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
115334919  VPS18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
115345325  VPS33A; vacuolar protein sorting-associated protein 33A [KO:K20182]
115333688  VPS39; vam6/Vps39-like protein isoform X1 [KO:K20183]
115339395  VPS41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
115346942  rab-interacting lysosomal protein isoform X2 [KO:K13883]
115352315  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
115353229  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 isoform X1 [KO:K10414]
115343199  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
115339601  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
115346015  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
115339916  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
115349807  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 isoform X1 [KO:K10417]
115345455  dynein light chain 1, cytoplasmic-like [KO:K10418]
115345457  dynein light chain 1, cytoplasmic [KO:K10418]
115347178  DYNLL2; dynein light chain 2, cytoplasmic isoform X1 [KO:K10418]
115339214  DYNLRB1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
115345909  DYNLRB2; dynein light chain roadblock-type 2 isoform X1 [KO:K10419]
115343897  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
115345162  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
115338088  DCTN1; dynactin subunit 1 isoform X1 [KO:K04648]
115351069  dynactin subunit 2-like isoform X1 [KO:K10424]
115338528  dynactin subunit 2-like isoform X1 [KO:K10424]
115337156  DCTN3; dynactin subunit 3 [KO:K10425]
121233012  dynactin subunit 3-like isoform X1 [KO:K10425]
115334023  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
115335655  DCTN5; dynactin subunit 5 [KO:K10427]
115344860  DCTN6; dynactin subunit 6 [KO:K10428]
115348018  ACTR1A; alpha-centractin [KO:K16575]
115334899  ACTR10; actin-related protein 10 [KO:K16576]
115352588  tubulin alpha-4 chain-like [KO:K07374]
115352590  tubulin alpha-4 chain isoform X1 [KO:K07374]
115347788  tubulin alpha-3 chain isoform X1 [KO:K07374]
115341771  tubulin alpha-3 chain [KO:K07374]
115341772  tubulin alpha-3 chain-like [KO:K07374]
115335082  tubulin alpha-8 chain [KO:K07374]
115342842  tubulin alpha chain [KO:K07374]
115342843  tubulin alpha-5 chain isoform X1 [KO:K07374]
115338302  TUBB; tubulin beta chain [KO:K07375]
115338810  TUBB1; tubulin beta-1 chain isoform X1 [KO:K07375]
115345828  TUBB3; tubulin beta-3 chain [KO:K07375]
115340337  TUBB6; tubulin beta-6 chain [KO:K07375]
115353117  tubulin beta-2 chain isoform X1 [KO:K07375]
115353118  tubulin beta-1 chain [KO:K07375]
115335015  TUBB4B; tubulin beta-4B chain [KO:K07375]
115338995  FYCO1; FYVE and coiled-coil domain-containing protein 1 isoform X1 [KO:K21954]
115353655  ARL8B; ADP-ribosylation factor-like protein 8B isoform X1 [KO:K07955]
115341422  ADP-ribosylation factor-like protein 8B [KO:K07955]
115335099  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
115342446  PLEKHM2; pleckstrin homology domain-containing family M member 2 isoform X2 [KO:K15348]
115343016  KIF5C; kinesin heavy chain isoform X1 [KO:K10396]
115338525  KIF5A; kinesin heavy chain isoform X1 [KO:K10396]
115339130  KIF5B; kinesin-1 heavy chain isoform X1 [KO:K10396]
115350205  KLC4; kinesin light chain 4 isoform X1 [KO:K10407]
115350941  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
115350182  ACBD3; Golgi resident protein GCP60 [KO:K23935]
115353760  RHOA; transforming protein RhoA [KO:K04513]
115352486  M6PR; cation-dependent mannose-6-phosphate receptor isoform X1 [KO:K10089]
115333762  RAB9B; ras-related protein Rab-9B [KO:K07900]
115334575  GCC2; GRIP and coiled-coil domain-containing protein 2 isoform X1 [KO:K20282]
115350157  PFN3; profilin-3 [KO:K05759]
115338398  PFN1; profilin-1 [KO:K05759]
115347298  PFN2; profilin-2 isoform X1 [KO:K05759]
115341375  EXOC7; exocyst complex component 7 isoform X1 [KO:K07195]
115351116  EXOC5; exocyst complex component 5 isoform X1 [KO:K19984]
115341897  EXOC4; exocyst complex component 4 [KO:K06111]
115353010  EXOC2; exocyst complex component 2 [KO:K17637]
115339402  RALA; ras-related protein Ral-A [KO:K07834]
115336033  ACTB; actin, cytoplasmic 1 [KO:K05692]
115340949  ACTG1; actin, cytoplasmic 2 [KO:K05692]
115341775  actin, cytoplasmic type 5 [KO:K05692]
115345948  S100A10; protein S100-A10 isoform X1 [KO:K17274]
115341983  ANXA2; annexin A2 [KO:K17092]
115337548  neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
115350204  LOW QUALITY PROTEIN: protein AHNAK2-like [KO:K23934]
115334705  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
115347077  ARHGEF26; rho guanine nucleotide exchange factor 26 [KO:K13744]
115333608  rho-related GTP-binding protein RhoG-like [KO:K07863]
115353331  RHOG; rho-related GTP-binding protein RhoG [KO:K07863]
115339255  ELMO1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
115339910  ELMO2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
115351142  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
115345956  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
115349922  MYL7; myosin regulatory light chain 2, atrial isoform isoform X1 [KO:K12754]
115339909  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
115347623  MYL10; myosin regulatory light chain 10 [KO:K12756]
115340208  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
115345705  FHOD1; FH1/FH2 domain-containing protein 1 [KO:K23938]
115342739  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
115335619  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X2 [KO:K04392]
115350954  NCKAP1L; nck-associated protein 1-like [KO:K05750]
115342778  NCKAP1; nck-associated protein 1 isoform X1 [KO:K05750]
115334045  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
115334479  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
115339505  ABI1; abl interactor 1 isoform X1 [KO:K23649]
115353777  BRK1; protein BRICK1 [KO:K05752]
115333637  LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
115353467  WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
115344937  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
115339685  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
115342867  ACTR3; actin-related protein 3 [KO:K18584]
115335690  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
115335785  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
115342627  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
115345332  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
121232467  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
115334855  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
115349403  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
115353441  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
115333461  PAK3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
115337574  MYO6; unconventional myosin-VI isoform X1 [KO:K10358]
115347173  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
115347305  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
115342450  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
115341839  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
115351797  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
115352825  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
115335244  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
115352807  CYTH4; cytohesin-4 isoform X1 [KO:K18441]
115340999  CYTH1; cytohesin-1 isoform X4 [KO:K18441]
115335756  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
115335288  ARF6; ADP-ribosylation factor 6 [KO:K07941]
115339761  ARF1; ADP-ribosylation factor 1 [KO:K07937]
115337142  sorting nexin-18 isoform X4 [KO:K17923]
115344517  SNX9; sorting nexin-9 [KO:K17923]
121232698  SNX18; sorting nexin-18 [KO:K17923]
115341865  SNX33; LOW QUALITY PROTEIN: sorting nexin-33 [KO:K17923]
115342183  WASL; neural Wiskott-Aldrich syndrome protein isoform X2 [KO:K23612]
115347951  DNM2; dynamin-2 isoform X1 [KO:K23484] [EC:3.6.5.5]
115339796  toll-like receptor 1 [KO:K10169]
115339865  toll-like receptor 2 type-1 [KO:K10159]
115339882  TLR2; toll-like receptor 2 [KO:K10159]
115344676  toll/interleukin-1 receptor domain-containing adapter protein isoform X1 [KO:K05403]
115339371  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
115335358  TLR4; toll-like receptor 4 [KO:K10160]
115340751  LY96; lymphocyte antigen 96 isoform X1 [KO:K05400]
115350015  TLR5; toll-like receptor 5 [KO:K10168]
115341041  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
115353383  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
115335051  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
115352340  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
115345137  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
115343621  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
115348471  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
115350500  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
115337413  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
115341473  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
115339005  NOD1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
115350471  heat shock protein HSP 90-beta isoform X2 [KO:K04079]
115352316  HSP90AA1; heat shock protein HSP 90-alpha isoform X1 [KO:K04079]
115352664  HSP90B1; endoplasmin [KO:K09487]
115340281  RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
115346445  LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 2-like [KO:K08846] [EC:2.7.11.1]
115339342  CSE1L; exportin-2 isoform X2 [KO:K18423]
115343754  KPNA1; importin subunit alpha-5 [KO:K23940]
115350660  KPNA3; importin subunit alpha-4 isoform X1 [KO:K23583]
115347074  KPNA4; importin subunit alpha-3 isoform X1 [KO:K23583]
115353553  RPS3; 40S ribosomal protein S3 [KO:K02985]
115351819  HRAS; GTPase HRas [KO:K02833]
115353699  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
115342153  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
115349300  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
115346261  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
115335899  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
115341693  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
115341623  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
115334823  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
115334828  mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
115341838  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
115341201  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
115348378  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
115338798  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
115334063  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
115347976  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
115333806  FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos [KO:K04379]
115348746  JUN; transcription factor AP-1 [KO:K04448]
115350114  interleukin-1 beta-like isoform X1 [KO:K04519]
115339802  IL6; LOW QUALITY PROTEIN: interleukin-6 [KO:K05405]
115340258  interleukin-8-like isoform X1 [KO:K10030]
115340259  interleukin-8-like [KO:K10030]
115340262  interleukin-8-like [KO:K10030]
115340268  C-X-C motif chemokine 5-like [KO:K10030]
115338857  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
115334089  TCF7; transcription factor 7 isoform X3 [KO:K02620]
115349900  TCF7L1; LOW QUALITY PROTEIN: transcription factor 7-like 1 [KO:K04490]
115348196  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
115343254  LEF1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
115340741  MYC; LOW QUALITY PROTEIN: myc proto-oncogene protein [KO:K04377]
115341106  FBXO22; F-box only protein 22 isoform X1 [KO:K10302]
115334091  SKP1; S-phase kinase-associated protein 1 isoform X1 [KO:K03094]
115343515  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X2 [KO:K03158]
115335375  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
115345654  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
115353209  inhibitor of apoptosis protein isoform X1 [KO:K16060]
115353096  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
115343703  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
115347472  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
115350118  tumor necrosis factor receptor superfamily member 10A-like isoform X3 [KO:K04722]
115351998  FADD; FAS-associated death domain protein [KO:K02373]
115343326  caspase-8-like [KO:K04398] [EC:3.4.22.61]
115342550  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
115335157  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
115339645  cytochrome c [KO:K08738]
115353069  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
115337302  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
115349915  caspase-3-like [KO:K04397] [EC:3.4.22.60]
115347960  CASP7; caspase-7 isoform X2 [KO:K04397] [EC:3.4.22.60]
115351279  RHOB; rho-related GTP-binding protein RhoB [KO:K07856]
115347110  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
115350251  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
115338049  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
115338050  RAC-beta serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
115347910  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
115346122  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
115336435  TXN; thioredoxin isoform X2 [KO:K03671]
115352362  TXN2; thioredoxin, mitochondrial [KO:K03671]
115350257  NLRC4; LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 4 [KO:K12805]
115346730  caspase-1-like [KO:K01370] [EC:3.4.22.36]
115345010  IL18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
achc04010  MAPK signaling pathway
achc04210  Apoptosis
achc04217  Necroptosis
achc04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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