KEGG   PATHWAY: pviv04510
Entry
pviv04510                   Pathway                                
Name
Focal adhesion - Prionailurus viverrinus (fishing cat)
Description
Cell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where bundles of actin filaments are anchored to transmembrane receptors of the integrin family through a multi-molecular complex of junctional plaque proteins. Some of the constituents of focal adhesions participate in the structural link between membrane receptors and the actin cytoskeleton, while others are signalling molecules, including different protein kinases and phosphatases, their substrates, and various adapter proteins. Integrin signaling is dependent upon the non-receptor tyrosine kinase activities of the FAK and src proteins as well as the adaptor protein functions of FAK, src and Shc to initiate downstream signaling events. These signalling events culminate in reorganization of the actin cytoskeleton; a prerequisite for changes in cell shape and motility, and gene expression. Similar morphological alterations and modulation of gene expression are initiated by the binding of growth factors to their respective receptors, emphasizing the considerable crosstalk between adhesion- and growth factor-mediated signalling.
Class
Cellular Processes; Cellular community - eukaryotes
Pathway map
pviv04510  Focal adhesion
pviv04510

Other DBs
GO: 0005925
Organism
Prionailurus viverrinus (fishing cat) [GN:pviv]
Gene
125158627  COL1A1; collagen alpha-1(I) chain isoform X1 [KO:K06236]
125161150  COL1A2; collagen alpha-2(I) chain [KO:K06236]
125170867  COL2A1; collagen alpha-1(II) chain [KO:K19719]
125162119  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
125162130  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
125157295  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
125157548  COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
125173315  COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
125173316  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
125158880  COL6A3; collagen alpha-3(VI) chain isoform X1 [KO:K06238]
125159082  COL6A2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
125159088  COL6A1; collagen alpha-1(VI) chain [KO:K06238]
125174422  COL6A6; collagen alpha-6(VI) chain [KO:K06238]
125175170  collagen alpha-4(VI) chain-like [KO:K06238]
125175500  COL6A5; collagen alpha-5(VI) chain isoform X1 [KO:K06238]
125166320  COL9A1; collagen alpha-1(IX) chain [KO:K08131]
125171769  COL9A2; collagen alpha-2(IX) chain [KO:K08131]
125162329  COL9A3; collagen alpha-3(IX) chain [KO:K08131]
125165961  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
125148766  LAMA1; laminin subunit alpha-1 isoform X1 [KO:K05637]
125161630  LAMA5; laminin subunit alpha-5 isoform X1 [KO:K06240]
125148702  LAMA3; laminin subunit alpha-3 isoform X1 [KO:K06240]
125166189  LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241]
125151448  LAMB1; laminin subunit beta-1 [KO:K05636]
125148915  LAMB2; laminin subunit beta-2 isoform X1 [KO:K06243]
125155428  LAMB3; laminin subunit beta-3 [KO:K06244]
125151455  LAMB4; laminin subunit beta-4 [KO:K06245]
125155356  LAMC1; laminin subunit gamma-1 [KO:K05635]
125155688  LAMC2; laminin subunit gamma-2 [KO:K06246]
125150287  LAMC3; laminin subunit gamma-3 [KO:K06247]
125151926  CHAD; chondroadherin [KO:K06248]
125161025  RELN; reelin [KO:K06249] [EC:3.4.21.-]
125168227  THBS1; thrombospondin-1 [KO:K16857]
125166172  THBS2; thrombospondin-2 [KO:K04659]
125173513  THBS4; thrombospondin-4 [KO:K04659]
125155647  THBS3; thrombospondin-3 [KO:K04659]
125156766  COMP; cartilage oligomeric matrix protein [KO:K04659]
125172662  FN1; fibronectin isoform X1 [KO:K05717]
125163269  SPP1; osteopontin isoform X1 [KO:K06250]
125152079  VTN; vitronectin [KO:K06251]
125166098  TNXB; tenascin-X isoform X1 [KO:K06252]
125155175  TNN; tenascin-N isoform X1 [KO:K06252]
125155460  TNR; tenascin-R [KO:K06252]
125150097  TNC; tenascin isoform X1 [KO:K06252]
125170119  VWF; von Willebrand factor [KO:K03900]
125164694  IBSP; bone sialoprotein 2 [KO:K06253]
125148667  ITGA1; integrin alpha-1 isoform X1 [KO:K06480]
125172671  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
125158705  ITGA2B; integrin alpha-IIb isoform X1 [KO:K06476]
125158524  ITGA3; integrin alpha-3 [KO:K06482]
125172067  ITGA4; integrin alpha-4 isoform X1 [KO:K06483]
125170000  ITGA5; integrin alpha-5 [KO:K06484]
125171916  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
125170187  ITGA7; integrin alpha-7 isoform X1 [KO:K06583]
125171108  ITGA8; integrin alpha-8 [KO:K06584]
125174963  ITGA9; integrin alpha-9 isoform X1 [KO:K06585]
125173824  ITGA10; integrin alpha-10 isoform X1 [KO:K06586]
125167533  ITGA11; integrin alpha-11 [KO:K06587]
125172290  ITGAV; integrin alpha-V isoform X1 [KO:K06487]
125170118  ITGB1; integrin beta-1 [KO:K05719]
125152049  ITGB3; integrin beta-3 [KO:K06493]
125151589  ITGB4; integrin beta-4 isoform X1 [KO:K06525]
125174964  ITGB5; integrin beta-5 [KO:K06588]
125173514  ITGB6; integrin beta-6 [KO:K06589]
125169707  ITGB7; integrin beta-7 [KO:K06590]
125160558  ITGB8; integrin beta-8 [KO:K06591]
125154771  EMP2; epithelial membrane protein 2 [KO:K26256]
125154510  PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359]
125170976  PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
125146630  PDGFD; platelet-derived growth factor D isoform X1 [KO:K05450]
125164369  PDGFC; platelet-derived growth factor C isoform X1 [KO:K05450]
125164093  EGF; pro-epidermal growth factor [KO:K04357]
125171123  IGF1; insulin-like growth factor I isoform X1 [KO:K05459]
125165878  VEGFA; vascular endothelial growth factor A [KO:K05448]
125146750  VEGFB; vascular endothelial growth factor B isoform X1 [KO:K16858]
125168901  PGF; placenta growth factor isoform X1 [KO:K16859]
125164102  VEGFC; vascular endothelial growth factor C isoform X1 [KO:K05449]
125157092  VEGFD; vascular endothelial growth factor D [KO:K05449]
125160804  HGF; hepatocyte growth factor isoform X1 [KO:K05460]
125163328  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
125166177  PDGFRB; platelet-derived growth factor receptor beta isoform X1 [KO:K05089] [EC:2.7.10.1]
125167768  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
125164023  KDR; vascular endothelial growth factor receptor 2 isoform X1 [KO:K05098] [EC:2.7.10.1]
125160878  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
125175490  FLT1; vascular endothelial growth factor receptor 1 [KO:K05096] [EC:2.7.10.1]
125175108  FLT4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
125160764  MET; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
125158497  ERBB2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
125170872  EMP1; epithelial membrane protein 1 [KO:K26255]
125162234  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
125152865  ARHGAP35; rho GTPase-activating protein 35 [KO:K05732]
125168205  ARHGAP5; rho GTPase-activating protein 5 isoform X1 [KO:K13709]
125151867  RHOA; transforming protein RhoA [KO:K04513]
125162588  DIAPH1; protein diaphanous homolog 1 isoform X1 [KO:K05740]
125148757  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
125158293  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
125149299  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
125159238  MYL5; myosin light chain 5 [KO:K12753]
125153338  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
125161739  MYL9; myosin regulatory light polypeptide 9 isoform X1 [KO:K12755]
125154673  MYL10; myosin regulatory light chain 10 [KO:K12756]
125149159  myosin regulatory light polypeptide 9 [KO:K12757]
125149160  myosin regulatory light chain 12B [KO:K12757]
125154477  MYL11; myosin regulatory light chain 11 isoform X1 [KO:K12758]
125161644  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
125147138  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
125149178  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
125169821  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
125155200  PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X1 [KO:K12329]
125152784  PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform X1 [KO:K17457]
125166408  MYLK4; myosin light chain kinase family member 4 [KO:K00907] [EC:2.7.11.18]
125174822  MYLK; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
125153739  MYLK3; myosin light chain kinase 3 isoform X1 [KO:K00907] [EC:2.7.11.18]
125162472  MYLK2; myosin light chain kinase 2, skeletal/cardiac muscle [KO:K00907] [EC:2.7.11.18]
125159487  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
125160066  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
125150114  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
125151565  ACTG1; actin, cytoplasmic 2 [KO:K05692]
125154076  ACTB; actin, cytoplasmic 1 [KO:K05692]
125159032  RASGRF1; ras-specific guanine nucleotide-releasing factor 1 isoform X1 [KO:K04349]
125159604  CAPN2; calpain-2 catalytic subunit isoform X1 [KO:K03853] [EC:3.4.22.53]
125167278  ACTN1; alpha-actinin-1 isoform X1 [KO:K05699]
125153089  ACTN4; alpha-actinin-4 isoform X1 [KO:K05699]
125168191  TLN2; talin-2 isoform X1 [KO:K06271]
125150361  TLN1; talin-1 isoform X1 [KO:K06271]
125159301  FLNA; filamin-A isoform X1 [KO:K04437]
125156859  FLNB; filamin-B isoform X1 [KO:K27392]
125149468  PXN; paxillin isoform X1 [KO:K05760]
125176251  ILK; integrin-linked protein kinase [KO:K06272] [EC:2.7.11.1]
125154523  ZYX; zyxin [KO:K06273]
125152500  VASP; vasodilator-stimulated phosphoprotein isoform X1 [KO:K06274]
125147417  VCL; vinculin isoform X1 [KO:K05700]
125176669  PARVA; alpha-parvin [KO:K06275]
125170977  PARVB; beta-parvin isoform X1 [KO:K06275]
125170978  PARVG; gamma-parvin isoform X1 [KO:K06275]
125153912  PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1 [KO:K06276] [EC:2.7.11.1]
125167750  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125152911  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
125155304  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
125174815  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
125174795  CTNNB1; catenin beta-1 [KO:K02105]
125151135  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
125154310  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
125153700  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
125156382  PTK2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
125174838  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
125175184  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125172980  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125161995  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
125172124  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
125150373  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
125147837  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
125155191  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
125150066  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
125172425  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
125154068  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
125170706  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
125151943  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
125176605  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
125174749  PAK2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
125157540  PAK3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
125152776  PAK4; serine/threonine-protein kinase PAK 4 isoform X1 [KO:K05734] [EC:2.7.11.1]
125162541  PAK5; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
125167324  PAK6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
125172271  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
125153269  BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726]
125152159  CRK; adapter molecule crk isoform X1 [KO:K04438]
125149234  CRKL; crk-like protein [KO:K04438]
125148210  DOCK1; dedicator of cytokinesis protein 1 isoform X1 [KO:K13708]
125150689  RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1 [KO:K06277]
125172327  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
125169828  RAP1B; ras-related protein Rap-1b [KO:K07836]
125167460  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
125148372  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
125164491  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
125173215  JUN; transcription factor Jun [KO:K04448]
125152888  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
125160281  CAV1; caveolin-1 [KO:K06278]
125160280  CAV2; caveolin-2 isoform X1 [KO:K12958]
125160428  CAV3; caveolin-3 [KO:K12959]
125165365  FYN; tyrosine-protein kinase Fyn isoform X1 [KO:K05703] [EC:2.7.10.2]
125155101  SHC1; SHC-transforming protein 1 isoform X1 [KO:K06279]
125159758  SHC2; SHC-transforming protein 2 isoform X1 [KO:K17447]
125150616  SHC3; SHC-transforming protein 3 [KO:K17448]
125168731  SHC4; SHC-transforming protein 4 [KO:K17449]
125151442  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
125167677  SOS2; son of sevenless homolog 2 isoform X1 [KO:K03099]
125161831  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
125146782  HRAS; GTPase HRas isoform X1 [KO:K02833]
125152491  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
125167652  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
125154521  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
125149069  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
125157234  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
125176918  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
125169721  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
125165233  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
125176505  baculoviral IAP repeat-containing protein 3-like [KO:K16060]
125177055  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
125157223  XIAP; E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
125176067  BAD; bcl2-associated agonist of cell death [KO:K02158]
125149087  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
Compound
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:14756624
  Authors
Berman AE, Kozlova NI, Morozevich GE.
  Title
Integrins: structure and signaling.
  Journal
Biochemistry (Mosc) 68:1284-99 (2003)
DOI:10.1023/b:biry.0000011649.03634.74
Reference
PMID:15179030
  Authors
Lee JW, Juliano R.
  Title
Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways.
  Journal
Mol Cells 17:188-202 (2004)
Reference
PMID:11573199
  Authors
Danen EH, Yamada KM.
  Title
Fibronectin, integrins, and growth control.
  Journal
J Cell Physiol 189:1-13 (2001)
DOI:10.1002/jcp.1137
Reference
PMID:15459662
  Authors
Guo W, Giancotti FG.
  Title
Integrin signalling during tumour progression.
  Journal
Nat Rev Mol Cell Biol 5:816-26 (2004)
DOI:10.1038/nrm1490
Reference
PMID:11229600
  Authors
Petit V, Thiery JP.
  Title
Focal adhesions: structure and dynamics.
  Journal
Biol Cell 92:477-94 (2000)
DOI:10.1016/S0248-4900(00)01101-1
Reference
PMID:12235283
  Authors
Stupack DG, Cheresh DA.
  Title
Get a ligand, get a life: integrins, signaling and cell survival.
  Journal
J Cell Sci 115:3729-38 (2002)
DOI:10.1242/jcs.00071
Reference
PMID:12640026
  Authors
Parsons JT.
  Title
Focal adhesion kinase: the first ten years.
  Journal
J Cell Sci 116:1409-16 (2003)
DOI:10.1242/jcs.00373
Reference
PMID:15688067
  Authors
Mitra SK, Hanson DA, Schlaepfer DD.
  Title
Focal adhesion kinase: in command and control of cell motility.
  Journal
Nat Rev Mol Cell Biol 6:56-68 (2005)
DOI:10.1038/nrm1549
Reference
PMID:14519391
  Authors
Comoglio PM, Boccaccio C, Trusolino L.
  Title
Interactions between growth factor receptors and adhesion molecules: breaking the rules.
  Journal
Curr Opin Cell Biol 15:565-71 (2003)
DOI:10.1016/S0955-0674(03)00096-6
Reference
PMID:15108811
  Authors
Schlaepfer DD, Mitra SK.
  Title
Multiple connections link FAK to cell motility and invasion.
  Journal
Curr Opin Genet Dev 14:92-101 (2004)
DOI:10.1016/j.gde.2003.12.002
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:10698680
  Authors
Vanhaesebroeck B, Alessi DR.
  Title
The PI3K-PDK1 connection: more than just a road to PKB.
  Journal
Biochem J 346 Pt 3:561-76 (2000)
DOI:10.1042/bj3460561
Reference
PMID:11882383
  Authors
Nicholson KM, Anderson NG.
  Title
The protein kinase B/Akt signalling pathway in human malignancy.
  Journal
Cell Signal 14:381-95 (2002)
DOI:10.1016/S0898-6568(01)00271-6
Reference
PMID:15053919
  Authors
Oloumi A, McPhee T, Dedhar S.
  Title
Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase.
  Journal
Biochim Biophys Acta 1691:1-15 (2004)
DOI:10.1016/j.bbamcr.2003.12.002
Reference
PMID:11146675
  Authors
Turner CE.
  Title
Paxillin and focal adhesion signalling.
  Journal
Nat Cell Biol 2:E231-6 (2000)
DOI:10.1038/35046659
Reference
PMID:15034601
  Authors
Hlobilkova A, Knillova J, Bartek J, Lukas J, Kolar Z.
  Title
The mechanism of action of the tumour suppressor gene PTEN.
  Journal
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:19-25 (2003)
Related
pathway
pviv04010  MAPK signaling pathway
pviv04060  Cytokine-cytokine receptor interaction
pviv04070  Phosphatidylinositol signaling system
pviv04110  Cell cycle
pviv04151  PI3K-Akt signaling pathway
pviv04310  Wnt signaling pathway
pviv04512  ECM-receptor interaction
pviv04810  Regulation of actin cytoskeleton
KO pathway
ko04510   
LinkDB

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