KEGG ORTHOLOGY: K05147

ORTHOLOGY: K05147

Entry

K05147                      KO

Symbol

TNFRSF11A, RANK, CD265

Name

tumor necrosis factor receptor superfamily member 11A

Pathway

map04060

Cytokine-cytokine receptor interaction

map04064

NF-kappa B signaling pathway

map04380

Osteoclast differentiation

map04917

Prolactin signaling pathway

map05323

Rheumatoid arthritis

Disease

H00436

Osteopetrosis

H00437

Paget disease of bone

H02042

Familial expansile osteolysis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
   04090 CD molecules
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
Cytokine receptors [BR:ko04050]
Tumor necrosis factor receptors
  TNF receptor superfamily
   K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
CD molecules [BR:ko04090]
Proteins
  K05147  CD265, TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB

Other DBs

GO:

0005031

Genes

HSA:	8792(TNFRSF11A)

PTR:	468560(TNFRSF11A)

PPS:	100991913(TNFRSF11A)

GGO:	101133276(TNFRSF11A)

PON:	100433235(TNFRSF11A)

PPYG:

129019034(TNFRSF11A)

NLE:	100600585(TNFRSF11A)

HMH:	116468497(TNFRSF11A)

SSYN:

129488118(TNFRSF11A)

MCC:	100424175(TNFRSF11A)

MCF:	102128119(TNFRSF11A)

MTHB:

126941005

MNI:	105477014(TNFRSF11A)

CSAB:

103244174(TNFRSF11A)

CATY:

105589999(TNFRSF11A)

PANU:

101022304(TNFRSF11A)

TGE:	112611536(TNFRSF11A)

MLEU:

105527895(TNFRSF11A)

RRO:	104682263(TNFRSF11A)

RBB:	108526386(TNFRSF11A)

TFN:	117099680(TNFRSF11A)

PTEH:

111528439(TNFRSF11A)

CANG:

105520043(TNFRSF11A)

CJC:	100393710(TNFRSF11A)

SBQ:	101052330(TNFRSF11A)

CIMI:

108304596(TNFRSF11A)

ANAN:

105712944(TNFRSF11A)

CSYR:

103276223(TNFRSF11A)

MMUR:

105876741(TNFRSF11A)

LCAT:

123621731(TNFRSF11A)

ERUF:

138383247(TNFRSF11A)

PCOQ:

105811140(TNFRSF11A)

OGA:	100948400(TNFRSF11A)

MMU:	21934(Tnfrsf11a)

MCAL:

110303160(Tnfrsf11a)

MPAH:

110322494(Tnfrsf11a)

RNO:	498206(Tnfrsf11a)

MCOC:

116097162(Tnfrsf11a)

ANU:	117716048(Tnfrsf11a)

ASYL:

127697563(Tnfrsf11a)

MUN:	110539357(Tnfrsf11a)

CGE:	100753416(Tnfrsf11a)

MAUA:

101836476(Tnfrsf11a)

PROB:

127236303(Tnfrsf11a)

PLEU:

114702813(Tnfrsf11a)

PMAV:

102921112(Tnfrsf11a)

MORG:

121446381(Tnfrsf11a)

MFOT:

126487114

AAMP:

119828067(Tnfrsf11a)

CNL:	130874783(Tnfrsf11a)

NGI:	103740116(Tnfrsf11a)

HGL:	101718050(Tnfrsf11a)

CPOC:

100724119(Tnfrsf11a)

CCAN:

109685497(Tnfrsf11a)

DORD:

105987596(Tnfrsf11a)

DSP:	122098059(Tnfrsf11a)

DMER:

138831807(Tnfrsf11a)

PLOP:

125363986(Tnfrsf11a)

NCAR:

124965666

MMMA:

107139299(Tnfrsf11a)

ITI:	101970043(Tnfrsf11a)

OCU:

100358260

OPI:	101523989(TNFRSF11A)

OCZ:	121159521(TNFRSF11A)

TUP:	102482158(TNFRSF11A)

GVR:	103597810(TNFRSF11A)

CFA:	483957(TNFRSF11A)

CLUD:

112644038(TNFRSF11A)

VVP:	112919200(TNFRSF11A)

VLG:	121481946(TNFRSF11A)

NPO:	129495392 129514429

AML:	100483336(TNFRSF11A)

UMR:	103676207(TNFRSF11A)

UAH:	113253483(TNFRSF11A)

UAR:	123787445(TNFRSF11A)

ELK:

111154251

LLV:

125081934

MPUF:

101680743(TNFRSF11A)

MNP:	132023664(TNFRSF11A)

MLK:	131811059(TNFRSF11A)

NVS:	122903559(TNFRSF11A)

ORO:	101379212(TNFRSF11A)

EJU:	114208897(TNFRSF11A)

ZCA:	113913070(TNFRSF11A)

MLX:	118004720(TNFRSF11A)

NSU:	110577009(TNFRSF11A)

LWW:	102725679(TNFRSF11A)

FCA:	101090651(TNFRSF11A)

PYU:	121032689(TNFRSF11A)

PCOO:

112868151(TNFRSF11A)

PBG:	122470825(TNFRSF11A)

PVIV:

125149131(TNFRSF11A)

LRUF:

124517005

LGF:	123587401(TNFRSF11A)

AJU:

113602289

PTG:	102957203(TNFRSF11A)

PPAD:

109275640

PUC:

125914483

PLEZ:

122203510(TNFRSF11A)

HHV:	120230802(TNFRSF11A)

BTA:	530884(TNFRSF11A)

BOM:	102286841(TNFRSF11A)

BIU:	109577693(TNFRSF11A)

BBUB:

102395034(TNFRSF11A)

BKE:	129636072(TNFRSF11A)

BBIS:

104999276(TNFRSF11A)

CHX:	102182930(TNFRSF11A)

OAS:	101118842(TNFRSF11A)

BTAX:

128067381(TNFRSF11A)

CSUM:

138097497(TNFRSF11A)

ODA:	120880868(TNFRSF11A)

CCAD:

122425568(TNFRSF11A)

MREE:

136167688(TNFRSF11A)

OVR:	110145355(TNFRSF11A)

MBEZ:

129549897(TNFRSF11A)

SSC:	100521706(TNFRSF11A)

CFR:	102523321(TNFRSF11A)

CBAI:

105073987(TNFRSF11A)

CDK:	105088996(TNFRSF11A)

VPC:	102538597(TNFRSF11A)

BACU:

103010843(TNFRSF11A)

BMUS:

118880303(TNFRSF11A)

LVE:	103084330(TNFRSF11A)

OOR:	101270027(TNFRSF11A)

LALB:

132504241(TNFRSF11A)

GMF:	115859310(TNFRSF11A)

DDP:	132436654(TNFRSF11A)

DLE:	111180204(TNFRSF11A)

PCAD:

102988430(TNFRSF11A)

PSIU:

116739059(TNFRSF11A)

PPHC:

136132495(TNFRSF11A)

NASI:

112406150(TNFRSF11A)

ECB:	100056617(TNFRSF11A)

EPZ:	103562575(TNFRSF11A)

EAI:	106832859(TNFRSF11A)

MYB:	102249492(TNFRSF11A)

MYD:	102768589(TNFRSF11A)

MMYO:

118663514(TNFRSF11A)

MLF:	102442443(TNFRSF11A)

MDT:	132239653(TNFRSF11A)

MYUM:

139013482(TNFRSF11A)

PKL:	118707437(TNFRSF11A)

EFUS:

103305060(TNFRSF11A)

MNA:	107545409(TNFRSF11A)

DRO:	112322858(TNFRSF11A)

SHON:

118979338(TNFRSF11A)

AJM:	119057577(TNFRSF11A)

PDIC:

114506631(TNFRSF11A)

PHAS:

123825986(TNFRSF11A)

MMF:	118618881(TNFRSF11A)

PPAM:

129078598(TNFRSF11A)

HAI:	109390774(TNFRSF11A)

RFQ:	117038716(TNFRSF11A)

PALE:

102886170(TNFRSF11A)

PGIG:

120584464(TNFRSF11A)

PVP:	105292754(TNFRSF11A)

RAY:	107501393(TNFRSF11A)

TOD:	119243744(TNFRSF11A)

SARA:

101546859(TNFRSF11A)

SFUM:

130016299(TNFRSF11A)

SETR:

126020210(TNFRSF11A)

LAV:	100661891(TNFRSF11A)

TMU:

101355445

ETF:	101662753(TNFRSF11A)

DNM:	101416909(TNFRSF11A)

MDO:	100024621(TNFRSF11A)

GAS:	123252984(TNFRSF11A)

SHR:	100914694(TNFRSF11A)

AFZ:

127543675

PCW:	110214743(TNFRSF11A)

TVP:	118834726(TNFRSF11A)

PBRV:

138170737(TNFRSF11A)

MLAO:

141503043(TNFRSF11A)

OAA:	100084001(TNFRSF11A)

TACU:

119948807(TNFRSF11A)

GGA:	769909(TNFRSF11A)

PCOC:

116226386(TNFRSF11A)

MGP:	100545473(TNFRSF11A)

CJO:	107309599(TNFRSF11A)

TPAI:

128087820(TNFRSF11A)

LMUT:

125690958(TNFRSF11A)

NMEL:

110393862(TNFRSF11A)

APLA:

101797241(TNFRSF11A)

AACU:

137850640(TNFRSF11A)

ACYG:

125184294(TNFRSF11A)

CATA:

118251046(TNFRSF11A)

AFUL:

116485599(TNFRSF11A)

TGU:	100232567(TNFRSF11A)

LSR:	110470694(TNFRSF11A)

SCAN:

103815299(TNFRSF11A)

PMOA:

120508366(TNFRSF11A)

OTC:	121348369(TNFRSF11A)

PRUF:

121358071(TNFRSF11A)

ATRC:

139603045(TNFRSF11A)

GFR:	102032337(TNFRSF11A)

FAB:	101817392(TNFRSF11A)

OMA:	130249738(TNFRSF11A)

PHI:	102100864(TNFRSF11A)

PMAJ:

107200749(TNFRSF11A)

CCAE:

111923866(TNFRSF11A)

CCW:	104698173(TNFRSF11A)

CBRC:

103618677(TNFRSF11A)

ACOE:

138106921(TNFRSF11A)

ETL:	114070086(TNFRSF11A)

ZAB:	102071513(TNFRSF11A)

ZLE:	135444172(TNFRSF11A)

ACHL:

103806791(TNFRSF11A)

SVG:	106850819(TNFRSF11A)

MMEA:

130577630(TNFRSF11A)

HRT:	120756843(TNFRSF11A)

SATI:

136365538(TNFRSF11A)

CCIC:

134047957(TNFRSF11A)

FPG:	101915765(TNFRSF11A)

FCH:	102053918(TNFRSF11A)

CCRI:

104164061(TNFRSF11A)

NNT:	104409968(TNFRSF11A)

SHAB:

115617029(TNFRSF11A)

ACUN:

113477373(TNFRSF11A)

TALA:

104363440(TNFRSF11A)

ACHC:

115353144(TNFRSF11A)

HALD:

104325525(TNFRSF11A)

HLE:	104843203(TNFRSF11A)

AGEN:

126048726

HHAR:

128138950(TNFRSF11A)

BBUT:

142042413(TNFRSF11A)

GCL:

127013681

CSTI:

104551737(TNFRSF11A)

LDI:	104354084(TNFRSF11A)

MNB:	103771747(TNFRSF11A)

DPUB:

104304238(TNFRSF11A)

PPUS:

135184779(TNFRSF11A)

AVIT:

104277158(TNFRSF11A)

BRHI:

104499452(TNFRSF11A)

EGZ:	104123471(TNFRSF11A)

NNI:	104021923(TNFRSF11A)

PCRI:

104033115

PCAO:

104043732(TNFRSF11A)

PARX:

142053092(TNFRSF11A)

PADL:

103919228(TNFRSF11A)

AFOR:

103898878(TNFRSF11A)

FGA:	104084051(TNFRSF11A)

CBOR:

142079040(TNFRSF11A)

GSTE:

104252404(TNFRSF11A)

CBOY:

140647929(TNFRSF11A)

MAME:

142405872(TNFRSF11A)

CLV:	102095161(TNFRSF11A)

CNIC:

135985388(TNFRSF11A)

MUI:	104541029(TNFRSF11A)

PGUU:

104468715(TNFRSF11A)

PLET:

104617313

EHS:	104514309(TNFRSF11A)

CMAC:

104477169(TNFRSF11A)

CUCA:

104066954(TNFRSF11A)

TEO:	104379466(TNFRSF11A)

BREG:

104637139(TNFRSF11A)

OHA:	104331225(TNFRSF11A)

ACAR:

104532179(TNFRSF11A)

CPEA:

104391627(TNFRSF11A)

CVF:	104286665(TNFRSF11A)

RTD:	128906093(TNFRSF11A)

CRID:

134511702(TNFRSF11A)

LMIC:

141739248(TNFRSF11A)

AAM:	106500204(TNFRSF11A)

AROW:

112972799(TNFRSF11A)

NPD:	112943415(TNFRSF11A)

TGT:	104580963(TNFRSF11A)

DNE:	112992544(TNFRSF11A)

SCAM:

104153866(TNFRSF11A)

ASN:	102381076(TNFRSF11A)

AMJ:	102575500(TNFRSF11A)

CPOO:

109314845(TNFRSF11A)

GGN:	109300837(TNFRSF11A)

PSS:	102446357(TNFRSF11A)

CIZ:	142008680(TNFRSF11A)

CMY:	102947144(TNFRSF11A)

CCAY:

125630959(TNFRSF11A)

LKP:	140906132(TNFRSF11A)

NDS:	141982682(TNFRSF11A)

DCC:	119851327(TNFRSF11A)

CPIC:

101939664(TNFRSF11A)

TST:	117873073(TNFRSF11A)

CABI:

116829418(TNFRSF11A)

MRV:	120396452(TNFRSF11A)

ACS:	100559342(tnfrsf11a)

ASAO:

132773471(TNFRSF11A)

PVT:	110075410(TNFRSF11A)

SUND:

121927966(TNFRSF11A)

PBI:	103067162(TNFRSF11A)

PMUR:

107283579(TNFRSF11A)

CTIG:

120304238

TSR:	106551816(TNFRSF11A)

PGUT:

117674764(TNFRSF11A)

PCAE:

139316019(TNFRSF11A)

APRI:

131195816(TNFRSF11A)

PTEX:

113436592(TNFRSF11A)

NSS:	113417140(TNFRSF11A)

VKO:	123021616(TNFRSF11A)

PMUA:

114600983(TNFRSF11A)

PRAF:

128417863(TNFRSF11A)

ZVI:	118090087(TNFRSF11A)

HCG:	128352962(TNFRSF11A)

GJA:

107124868

STOW:

125438779(TNFRSF11A)

EMC:	129333013(TNFRSF11A)

XLA:	108719099 108720089

XTR:	100101765(tnfrsf11a)

NPR:

108798474

RTEM:

120940629(TNFRSF11A)

ACAT:

141144841(TNFRSF11A)

PADS:

140331095(TNFRSF11A)

BBUF:

121001210(TNFRSF11A)

BGAR:

122939606(TNFRSF11A)

DTC:	141052873(TNFRSF11A)

PWL:	138280466(TNFRSF11A)

MUO:	115470241(TNFRSF11A)

GSH:	117355899(TNFRSF11A)

DRE:	100333821(tnfrsf11a)

SRX:	107727236 107758279

SANH:

107686692 107695382

SGH:	107584986 107595139

CCAR:

109049938 109113597(tnfrsf11a)

CAUA:

113042261 113066028

CGIB:

127945885 128013143

PTET:

122330154(tnfrsf11a)

LROH:

127155865(tnfrsf11a)

GRF:	141300716(tnfrsf11a)

OMC:	131533178(tnfrsf11a)

PPRM:

120475960(tnfrsf11a)

RKG:	130083809(tnfrsf11a)

MAMB:

125257994(tnfrsf11a)

CIDE:

127505873

CERY:

137014339(tnfrsf11a)

MASI:

127431523 127434270

TROS:

130547436(tnfrsf11a)

TDW:	130413707(tnfrsf11a)

MANU:

129426147(tnfrsf11a)

PDAB:

135740074(tnfrsf11a)

IPU:

108256716

IFU:	128599908(tnfrsf11a)

PHYP:

113541325(tnfrsf11a)

SMEO:

124375622(tnfrsf11a)

TFD:	113662461(tnfrsf11a)

TVC:	132840413(tnfrsf11a)

CGAR:

128513896(tnfrsf11a)

NGRA:

132867115(tnfrsf11a)

TRN:	134301214(tnfrsf11a)

AMEX:

103038583(tnfrsf11a)

CMAO:

118799055(tnfrsf11a)

EEE:

113591902

CHAR:

105905192(tnfrsf11a)

SPIL:

134066403(tnfrsf11a)

TRU:

101073524

TFS:	130513856(tnfrsf11a)

TNG:	GSTEN00015465G001

LCO:

104922590

NCC:

104957084

TBEN:

117484126(tnfrsf11a)

CGOB:

115025504

PGEO:

117465469(tnfrsf11a)

GACU:

117551868(tnfrsf11a)

EMAC:

134858077(tnfrsf11a)

ELY:	117264436(tnfrsf11a)

EFO:	125882086(tnfrsf11a)

PLEP:

121960598(tnfrsf11a)

SLUC:

116038000(tnfrsf11a)

ECRA:

117937550(tnfrsf11a)

ESP:

116671987

PFLV:

114549177(tnfrsf11a)

GAT:	120811540(tnfrsf11a)

PPUG:

119199024(tnfrsf11a)

AFB:	129111023(tnfrsf11a)

CLUM:

117749817(tnfrsf11a)

PSWI:

130206378(tnfrsf11a)

CANA:

137788605(tnfrsf11a)

CVE:	137871781(tnfrsf11a)

MSAM:

119898467 119908529(tnfrsf11a)

SCHU:

122866205(tnfrsf11a)

EARM:

139304537(tnfrsf11a)

CUD:	121527369(tnfrsf11a)

SPUL:

138595669(tnfrsf11a)

LMIX:

132994054(tnfrsf11a)

HTC:	141807594(tnfrsf11a)

ALAT:

119008252(tnfrsf11a)

ASTR:

137587782(tnfrsf11a)

PKLU:

139220844(tnfrsf11a)

MZE:	101466954(tnfrsf11a)

ONL:

100690186

OAU:	116328288(tnfrsf11a)

OLA:	101164015(tnfrsf11a)

OML:	112151047(tnfrsf11a)

CSAI:

133423634(tnfrsf11a)

XMA:

102229493

XCO:

114136920

XHE:	116711920(tnfrsf11a)

PRET:

103456530(tnfrsf11a)

PFOR:

103135257(tnfrsf11a)

PLAI:

106950787(tnfrsf11a)

PMEI:

106921313(tnfrsf11a)

GAF:	122824540(tnfrsf11a)

PPRL:

129364699(tnfrsf11a)

CVG:	107094196(tnfrsf11a)

CTUL:

119784621(tnfrsf11a)

GMU:	124858534(tnfrsf11a)

NFU:	107382986(tnfrsf11a)

KMR:	108243135(tnfrsf11a)

ALIM:

106517555(tnfrsf11a)

NWH:	119426897(tnfrsf11a)

AOCE:

111565920(tnfrsf11a)

EJA:	138199457(tnfrsf11a)

BFRE:

138624938(tnfrsf11a)

MCEP:

124996024(tnfrsf11a)

CSEM:

103376899(tnfrsf11a)

POV:	109629514(tnfrsf11a)

SSEN:

122778401(tnfrsf11a)

SSOE:

131470568(tnfrsf11a)

HHIP:

117754110(tnfrsf11a)

HSP:	118098397(tnfrsf11a)

PPLT:

128425998(tnfrsf11a)

SMAU:

118291037(tnfrsf11a)

LCF:	108900798(tnfrsf11a)

SDU:

111237298

SLAL:

111662986

XGL:	120790237(tnfrsf11a)

HCQ:	109515585(tnfrsf11a)

SSCV:

125986289(tnfrsf11a)

SBIA:

133492776(tnfrsf11a)

PEE:	133396835(tnfrsf11a)

PTAO:

133469960(tnfrsf11a)

BPEC:

110160990(tnfrsf11a)

ENY:	140364494(tnfrsf11a)

MALB:

109963718(tnfrsf11a)

BSPL:

114854337(tnfrsf11a)

SJO:	128382583(tnfrsf11a)

SSCO:

134002508(tnfrsf11a)

TTY:	137173236(tnfrsf11a)

GMH:	115537064(tnfrsf11a)

SASA:

106578407(tnfrsf11a) 106590556

STRU:

115152173 115195410

OTW:	112227660(tnfrsf11a)

OMY:	110489589 110535418(tnfrsf11a)

OGO:	123991251(tnfrsf11a) 124039495

ONE:	115120264 115127574

OKI:	109878545 109898992

OKE:	118374588(tnfrsf11a) 118382405

OMM:	135517163 135522750(tnfrsf11a)

OCLA:

139366679 139420312

SALP:

111973456 112080814

SNH:	120027902 120050307

SFON:

129822979(tnfrsf11a) 129858979

CCLU:

121549456(tnfrsf11a) 121570483

ELS:	105022048(tnfrsf11a)

OEP:	134035378(tnfrsf11a)

SFM:	108919669 108935562

PKI:

111837168

AANG:

118225693(tnfrsf11a) 118232880

AROT:

135253634(tnfrsf11a) 135260683

CCOG:

133127669(tnfrsf11a) 133137324

LOC:	102696720(tnfrsf11a)

PSPA:

121312788 121314246

ARUT:

117394820 117399794

LCM:

102354842

BBEL:

109463374 109470118 109480297

BGT:

106058294

OSN:

115224692

» show all

Reference

PMID:9367155

Authors

Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L

Title

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Journal

Nature 390:175-9 (1997)
DOI:10.1038/36593

Sequence

[hsa:8792]

Reference

PMID:21445556

Authors

Hanada R, Hanada T, Sigl V, Schramek D, Penninger JM

Title

RANKL/RANK-beyond bones.

Journal

J Mol Med (Berl) 89:647-56 (2011)
DOI:10.1007/s00109-011-0749-z

LinkDB

DBGET integrated database retrieval system