KEGG   PATHWAY: ko04080Help
Entry
ko04080                     Pathway                                

Name
Neuroactive ligand-receptor interaction
Class
Environmental Information Processing; Signaling molecules and interaction
BRITE hierarchy
Pathway map
ko04080  Neuroactive ligand-receptor interaction
ko04080

Ortholog table
Disease
H00249  Thyroid hormone resistance syndrome
H00255  Hypogonadotropic hypogonadism
H00667  Woolly hair
H00680  Primary failure of tooth eruption
H00759  Waardenburg syndrome
H00769  Hyperekplexia
H00770  Congenital myasthenic syndrome
H00783  Febrile seizures
H00787  Congenital stationary night blindness
H00807  Nocturnal frontal lobe epilepsy
H00823  ABCD syndrome
H00910  Hirschsprung disease
H00937  Precocious puberty
H00986  Multiple pterygium syndrome
H01039  Ovarian hyperstimulation syndrome
H01206  Plasminogen deficiency
H01253  Isolated follicle-stimulating hormone deficiency
H01294  Nephrogenic syndrome of inappropriate antidiuresis
H01611  Alcohol dependence
H01649  Schizophrenia
H01671  Neurosis
H01682  Syndrome of inappropriate secretion of antidiuretic hormone
H01683  Disorders of antidiuretic hormone (ADH) secretion
H01700  Hypopituitarism
H01702  Glucocorticoid resistance syndrome
H01895  Attention deficit hyperactivity disorder (ADHD)
H02037  Laron syndrome
H02039  Kowarski syndrome
H02059  Leptin deficiency
H02060  Leptin receptor deficiency
H02106  Genetic obesity
Drug
D02546  Kainic acid hydrate (JP17)
D03694  Deslorelin (USAN/INN)
D04174  Fertirelin acetate (USAN)
D05076  Morantel tartrate (USP)
D08230  Morantel (BAN)
D08231  Morantel citrate
Orthology
K04129  muscarinic acetylcholine receptor M1
K04130  muscarinic acetylcholine receptor M2
K04131  muscarinic acetylcholine receptor M3
K04132  muscarinic acetylcholine receptor M4
K04133  muscarinic acetylcholine receptor M5
K04134  muscarinic acetylcholine receptor
K04135  adrenergic receptor alpha-1A
K04136  adrenergic receptor alpha-1B
K04137  adrenergic receptor alpha-1D
K04138  adrenergic receptor alpha-2A
K04139  adrenergic receptor alpha-2B
K04140  adrenergic receptor alpha-2C
K04141  adrenergic receptor beta-1
K04142  adrenergic receptor beta-2
K04143  adrenergic receptor beta-3
K04144  dopamine receptor D1
K04145  dopamine receptor D2
K04146  dopamine receptor D3
K04147  dopamine receptor D4
K05840  dopamine receptor D5
K04148  dopamine receptor D1-like
K04149  histamine receptor H1
K04150  histamine receptor H2
K04151  histamine receptor H3
K04152  histamine receptor H4
K04153  5-hydroxytryptamine receptor 1
K04157  5-hydroxytryptamine receptor 2
K04160  5-hydroxytryptamine receptor 4
K04161  5-hydroxytryptamine receptor 5
K04162  5-hydroxytryptamine receptor 6
K04163  5-hydroxytryptamine receptor 7
K05051  trace amine associated receptor
K09821  angiotensinogen
K04166  angiotensin II receptor type 1
K04167  angiotensin II receptor type 2
K05225  apelin
K04174  apelin receptor
K05223  neuromedin B
K05224  gastrin-releasing peptide
K04168  neuromedin B receptor
K04169  gastrin-releasing peptide receptor
K04170  bombesin receptor subtype-3
K03898  kininogen
K03915  bradykinin receptor B1
K03916  bradykinin receptor B2
K03990  complement component 3
K04009  C3a anaphylatoxin chemotactic receptor
K03994  complement component 5
K04010  C5a anaphylatoxin chemotactic receptor 1
K04172  formyl peptide receptor 1
K04173  formyl peptide receptor-like
K05226  cholecystokinin
K04194  cholecystokinin A receptor
K04195  cholecystokinin B receptor
K16366  endothelin-1
K16367  endothelin-2
K05227  endothelin-3
K04197  endothelin receptor type A
K04198  endothelin receptor type B
K05244  galanin
K04230  galanin receptor 1
K04231  galanin receptor 2
K04232  galanin receptor 3
K05254  ghrelin
K04284  growth hormone secretagogue receptor
K23140  metastasis-suppressor KiSS-1
K08374  KISS1 receptor
K05228  proopiomelanocortin
K04199  melanocortin 1 receptor
K04200  melanocortin 2 receptor
K04201  melanocortin 3 receptor
K04202  melanocortin 4 receptor
K04203  melanocortin 5 receptor
K05265  motilin
K05266  motilin receptor
K05249  neuromedin U
K05052  neuromedin U receptor 1
K05053  neuromedin U receptor 2
K05247  neuropeptide FF-amide peptide
K04240  neuropeptide FF receptor 1
K08375  neuropeptide FF receptor 2
K05232  neuropeptide Y
K05233  peptide YY
K05234  pancreatic polypeptide
K04204  neuropeptide Y receptor type 1
K04205  neuropeptide Y receptor type 2
K04206  neuropeptide Y receptor type 4
K04207  neuropeptide Y receptor type 5
K04208  neuropeptide Y receptor type 6
K04210  G protein-coupled receptor 83
K23141  neuropeptide W
K05267  preproneuropeptide B
K05268  neuropeptides B/W receptor 1
K08377  neuropeptides B/W receptor 2
K05235  neurotensin
K04211  neurotensin receptor 1
K04212  neurotensin receptor 2
K18832  proenkephalin A
K15840  proenkephalin B (prodynorphin)
K04213  delta-type opioid receptor
K04214  kappa-type opioid receptor
K04215  mu-type opioid receptor
K04216  nociceptin receptor
K05246  hypocretin (orexin) neuropeptide
K04238  hypocretin (orexin) receptor 1
K04239  hypocretin (orexin) receptor 2
K05243  oxytocin-neurophysin 1
K04229  oxytocin receptor
K05237  somatostatin
K05238  cortistatin
K04217  somatostatin receptor 1
K04218  somatostatin receptor 2
K04219  somatostatin receptor 3
K04220  somatostatin receptor 4
K04221  somatostatin receptor 5
K05239  tachykinin 1
K05241  tachykinin 4
K04222  tachykinin receptor 1
K04223  tachykinin receptor 2
K05240  tachykinin 2/3
K04224  tachykinin receptor 3
K05248  urotensin 2
K04241  urotensin 2 receptor
K05242  arginine vasopressin
K04226  arginine vasopressin receptor 1A
K04227  arginine vasopressin receptor 1B
K04228  arginine vasopressin receptor 2
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
K01319  cathepsin G [EC:3.4.21.20]
K01352  granzyme A [EC:3.4.21.78]
K01315  plasminogen [EC:3.4.21.7]
K01312  trypsin [EC:3.4.21.4]
K03914  coagulation factor II (thrombin) receptor
K04234  coagulation factor II (thrombin) receptor-like 1
K04235  coagulation factor II (thrombin) receptor-like 2
K04236  coagulation factor II (thrombin) receptor-like 3
K04237  partitioning defective protein 3
K05269  Prolactin-releasing peptide
K04314  prolactin releasing hormone receptor
K05229  pro-melanin-concentrating hormone
K04320  melanin-concentrating hormone receptor 1
K05054  melanin-concentrating hormone receptor 2
K05250  follitropin subunit beta
K08522  glycoprotein hormones alpha chain
K04247  follicle stimulating hormone receptor
K08521  lutropin subunit beta
K04248  lutropin-choriogonadotropic hormone receptor
K05251  thyrotropin subunit beta
K04249  thyrotropin receptor
K04332  prostaglandin D2 receptor
K04258  prostaglandin E receptor 1
K04259  prostaglandin E receptor 2
K04260  prostaglandin E receptor 3
K04261  prostaglandin E receptor 4
K04262  prostaglandin F receptor
K04263  prostacyclin receptor
K04264  thromboxane A2 receptor
K04265  adenosine receptor A1
K04266  adenosine receptor A2a
K04267  adenosine receptor A2b
K04268  adenosine receptor A3
K04269  P2Y purinoceptor 2
K04270  P2Y purinoceptor 1
K04271  P2Y purinoceptor 4
K04272  P2Y purinoceptor 6
K04273  lysophosphatidic acid receptor 6
K04274  P2Y purinoceptor 10
K04299  P2Y purinoceptor 14
K08386  P2Y purinoceptor 8
K08387  P2Y purinoceptor 11
K08388  P2Y purinoceptor 13
K04276  C-X-C chemokine receptor type 8
K04277  cannabinoid receptor 1
K04278  cannabinoid receptor 2
K04279  platelet-activating factor receptor
K05252  gonadotropin-releasing hormone
K04280  gonadotropin-releasing hormone receptor
K05253  thyrotropin-releasing hormone
K04282  thyrotropin-releasing hormone receptor
K04285  melatonin receptor type 1A
K04286  melatonin receptor type 1B
K04287  G protein-coupled receptor 50
K04289  lysophosphatidic acid receptor 1
K04291  lysophosphatidic acid receptor 2
K04294  lysophosphatidic acid receptor 3
K04275  lysophosphatidic acid receptor 4
K04288  sphingosine 1-phosphate receptor 1
K04292  sphingosine 1-phosphate receptor 2
K04290  sphingosine 1-phosphate receptor 3
K04293  sphingosine 1-phosphate receptor 4
K04295  sphingosine 1-phosphate receptor 5
K04296  leukotriene B4 receptor 1
K04297  leukotriene B4 receptor 2
K04303  proto-oncogene Mas
K21998  relaxin 1/2
K22000  relaxin 3
K21999  insulin-like 3
K22001  insulin-like 5
K04306  relaxin family peptide receptor 1
K04307  relaxin family peptide receptor 2
K08397  relaxin family peptide receptor 3
K08398  relaxin family peptide receptor 4
K04322  cysteinyl leukotriene receptor 1
K04323  cysteinyl leukotriene receptor 2
K12332  calcitonin
K12333  adrenomedullin
K08039  islet amyloid polypeptide
K04576  calcitonin receptor
K04577  calcitonin receptor-like
K05256  corticotropin-releasing hormone
K23142  urcortin
K05257  urocortin 2/3
K04578  corticotropin releasing hormone receptor 1
K04579  corticotropin releasing hormone receptor 2
K05258  gastric inhibitory polypeptide
K04580  gastric inhibitory polypeptide receptor
K05259  glucagon
K04583  glucagon receptor
K04581  glucagon-like peptide 1 receptor
K04582  glucagon-like peptide 2 receptor
K05260  growth hormone-releasing hormone
K04584  growth hormone releasing hormone receptor
K05261  parathyroid hormone
K23143  tuberoinfundibular peptide of 39 residues
K04585  parathyroid hormone receptor 1
K04586  parathyroid hormone receptor 2
K05262  pituitary adenylate cyclase-activating polypeptide
K04587  pituitary adenylate cyclase-activating polypeptide type I receptor
K05263  secretin
K04588  secretin receptor
K05264  vasoactive intestinal peptide
K04589  vasoactive intestinal peptide receptor 1
K04590  vasoactive intestinal peptide receptor 2
K04603  metabotropic glutamate receptor 1
K04605  metabotropic glutamate receptor 2
K04606  metabotropic glutamate receptor 3
K04607  metabotropic glutamate receptor 4
K04604  metabotropic glutamate receptor 5
K04608  metabotropic glutamate receptor 6
K04609  metabotropic glutamate receptor 7
K04610  metabotropic glutamate receptor 8
K04615  gamma-aminobutyric acid type B receptor
K04617  gamma-aminobutyric acid type B receptor-like
K05208  glutamate receptor ionotropic, NMDA 1
K05209  glutamate receptor ionotropic, NMDA 2A
K05210  glutamate receptor ionotropic, NMDA 2B
K05211  glutamate receptor ionotropic, NMDA 2C
K05212  glutamate receptor ionotropic, NMDA 2D
K05213  glutamate receptor ionotropic, NMDA 3A
K05214  glutamate receptor ionotropic, NMDA 3B
K05175  gamma-aminobutyric acid receptor subunit alpha
K05181  gamma-aminobutyric acid receptor subunit beta
K05184  gamma-aminobutyric acid receptor subunit delta
K05185  gamma-aminobutyric acid receptor subunit epsilon
K05186  gamma-aminobutyric acid receptor subunit gamma
K05189  gamma-aminobutyric acid receptor subunit pi
K05190  gamma-aminobutyric acid receptor subunit rho
K05192  gamma-aminobutyric acid receptor subunit theta
K23681  secreted Ly-6/uPAR-related protein 1
K23682  secreted Ly-6/uPAR-related protein 2
K04803  nicotinic acetylcholine receptor alpha-1
K04804  nicotinic acetylcholine receptor alpha-2
K04805  nicotinic acetylcholine receptor alpha-3
K04806  nicotinic acetylcholine receptor alpha-4
K04807  nicotinic acetylcholine receptor alpha-5
K04808  nicotinic acetylcholine receptor alpha-6
K04809  nicotinic acetylcholine receptor alpha-7
K04810  nicotinic acetylcholine receptor alpha-9
K04811  nicotinic acetylcholine receptor alpha-10
K04812  nicotinic acetylcholine receptor beta-1
K04813  nicotinic acetylcholine receptor beta-2
K04814  nicotinic acetylcholine receptor beta-3
K04815  nicotinic acetylcholine receptor beta-4
K04816  nicotinic acetylcholine receptor delta
K04817  nicotinic acetylcholine receptor epsilon
K04818  nicotinic acetylcholine receptor gamma
K05215  P2X purinoceptor 1
K05216  P2X purinoceptor 2
K05217  P2X purinoceptor 3
K05218  P2X purinoceptor 4
K05219  P2X purinoceptor 5
K05220  P2X purinoceptor 7
K05221  P2X purinoceptor 6
K05197  glutamate receptor 1
K05198  glutamate receptor 2
K05199  glutamate receptor 3
K05200  glutamate receptor 4
K05201  glutamate receptor, ionotropic kainate 1
K05202  glutamate receptor, ionotropic kainate 2
K05203  glutamate receptor, ionotropic kainate 3
K05204  glutamate receptor, ionotropic kainate 4
K05205  glutamate receptor, ionotropic kainate 5
K05206  glutamate receptor delta-1 subunit
K05207  glutamate receptor delta-2 subunit
K05193  glycine receptor alpha-1
K05194  glycine receptor alpha-2
K05195  glycine receptor alpha-3
K05196  glycine receptor beta
K05222  transient receptor potential cation channel subfamily V member 1
K05770  translocator protein
K05771  glucocorticoid receptor
K05438  growth hormone
K05080  growth hormone receptor
K05547  thyroid hormone receptor alpha
K08362  thyroid hormone receptor beta
K05424  leptin
K05062  leptin receptor
K05439  prolactin
K05081  prolactin receptor
Compound
C00002  ATP
C00008  ADP
C00015  UDP
C00025  L-Glutamate
C00037  Glycine
C00049  L-Aspartate
C00075  UTP
C00099  beta-Alanine
C00212  Adenosine
C00245  Taurine
C00334  4-Aminobutanoate
C00388  Histamine
C00398  Tryptamine
C00483  Tyramine
C00506  L-Cysteate
C00547  L-Noradrenaline
C00584  Prostaglandin E2
C00639  Prostaglandin F2alpha
C00681  1-Acyl-sn-glycerol 3-phosphate
C00696  Prostaglandin D2
C00735  Cortisol
C00780  Serotonin
C00788  L-Adrenaline
C01120  Sphinganine 1-phosphate
C01312  Prostaglandin I2
C01516  Morphine
C01598  Melatonin
C01829  Thyroxine
C01996  Acetylcholine
C02165  Leukotriene B4
C02166  Leukotriene C4
C02198  Thromboxane A2
C02465  Triiodothyronine
C03758  Dopamine
C04227  Octopamine
C04598  2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine
C05113  Porphyrin
C05951  Leukotriene D4
C05952  Leukotriene E4
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C06865  Calcitonin
C11695  Anandamide
C12270  N-Acetylaspartylglutamate
C12271  N-Arachidonyl dopamine
C12272  N-Oleoyl dopamine
C13856  2-Arachidonoylglycerol
C15890  Endomorphin-1
C15891  Endomorphin-2
C15995  Bombesin
C16511  L-Homocysteic acid
C16512  Palmitoylethanolamide
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