KEGG   PATHWAY: arow05132
Entry
arow05132                   Pathway                                
Name
Salmonella infection - Apteryx rowi (Okarito brown kiwi)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
arow05132  Salmonella infection
arow05132

Organism
Apteryx rowi (Okarito brown kiwi) [GN:arow]
Gene
112978054  PODXL; podocalyxin [KO:K06817]
112976515  PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
112972069  RAB5A; ras-related protein Rab-5A [KO:K07887]
112961075  RAB5B; ras-related protein Rab-5B [KO:K07888]
112968726  RAB5C; ras-related protein Rab-5C [KO:K07889]
112977860  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
112970756  RAB7A; ras-related protein Rab-7a isoform X1 [KO:K07897]
112971659  RAB7B; ras-related protein Rab-7b isoform X1 [KO:K07898]
112965765  PLEKHM1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
112962105  VPS11; vacuolar protein sorting-associated protein 11 homolog isoform X1 [KO:K20179]
112971064  VPS16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
112966095  VPS18; vacuolar protein sorting-associated protein 18 homolog isoform X1 [KO:K20181]
112962513  VPS33A; vacuolar protein sorting-associated protein 33A isoform X1 [KO:K20182]
112964018  VPS39; vam6/Vps39-like protein isoform X1 [KO:K20183]
112973745  VPS41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
112960679  RILP; rab-interacting lysosomal protein [KO:K13883]
112972748  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 isoform X1 [KO:K10413]
112971947  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
112963904  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
112969387  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 [KO:K10415]
112977508  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 isoform X1 [KO:K10416]
112962296  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
112969239  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
112970639  dynein light chain 1, cytoplasmic [KO:K10418]
112970671  dynein light chain 2, cytoplasmic-like isoform X1 [KO:K10418]
112970672  dynein light chain 1, cytoplasmic-like [KO:K10418]
112973542  DYNLL2; dynein light chain 2, cytoplasmic isoform X1 [KO:K10418]
112974645  DYNLRB1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
112963306  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
112969454  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
112971551  DYNLT1; dynein light chain Tctex-type 1 isoform X1 [KO:K10420]
112971052  DCTN1; dynactin subunit 1 isoform X1 [KO:K04648]
112962408  DCTN2; dynactin subunit 2 [KO:K10424]
112977963  DCTN3; dynactin subunit 3 [KO:K10425]
112978150  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
112975574  DCTN5; dynactin subunit 5 isoform X1 [KO:K10427]
112978299  DCTN6; dynactin subunit 6 [KO:K10428]
112961657  beta-centractin [KO:K16575]
112967989  ACTR1A; alpha-centractin isoform X1 [KO:K16575]
112961239  ACTR10; actin-related protein 10 [KO:K16576]
112965087  tubulin alpha-8 chain [KO:K07374]
112965777  tubulin alpha-3 chain isoform X1 [KO:K07374]
112971981  tubulin alpha chain-like [KO:K07374]
112971982  tubulin alpha-5 chain-like [KO:K07374]
112972001  tubulin alpha-5 chain [KO:K07374]
112978102  tubulin alpha-3 chain isoform X1 [KO:K07374]
112978103  tubulin alpha-3 chain-like [KO:K07374]
112960845  tubulin alpha-1A chain [KO:K07374]
112968315  TUBA8; tubulin alpha-8 chain isoform X1 [KO:K07374]
112964161  tubulin beta chain-like [KO:K07375]
112964656  TUBB6; tubulin beta-6 chain [KO:K07375]
112960956  TUBB1; tubulin beta-1 chain [KO:K07375]
112967918  tubulin beta chain isoform X1 [KO:K07375]
112962975  TUBB4B; tubulin beta-4B chain [KO:K07375]
112975147  TUBB3; tubulin beta-3 chain [KO:K07375]
112977960  FYCO1; FYVE and coiled-coil domain-containing protein 1 isoform X1 [KO:K21954]
112970457  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
112965100  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
112966628  ADP-ribosylation factor-like protein 8A [KO:K07955]
112977492  PLEKHM2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
112977088  KIF5C; kinesin heavy chain [KO:K10396]
112962407  KIF5A; kinesin heavy chain [KO:K10396]
112963209  KIF5B; kinesin-1 heavy chain isoform X1 [KO:K10396]
112972602  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
112962244  KLC3; kinesin light chain 3 [KO:K10407]
112974366  KLC4; kinesin light chain 4 isoform X1 [KO:K10407]
112963420  ACBD3; Golgi resident protein GCP60 [KO:K23935]
112975194  RHOA; transforming protein RhoA [KO:K04513]
112973990  M6PR; cation-dependent mannose-6-phosphate receptor isoform X1 [KO:K10089]
112964598  RAB9A; ras-related protein Rab-9A [KO:K07899]
112966338  RAB9B; ras-related protein Rab-9B [KO:K07900]
112960871  GCC2; GRIP and coiled-coil domain-containing protein 2 isoform X1 [KO:K20282]
112965801  PFN2; profilin-2 [KO:K05759]
112966445  PFN3; profilin-3 [KO:K05759]
112967198  PFN4; profilin-4 isoform X1 [KO:K05759]
112977702  EXOC7; exocyst complex component 7 isoform X1 [KO:K07195]
112961242  EXOC5; exocyst complex component 5 [KO:K19984]
112978064  EXOC4; exocyst complex component 4 isoform X1 [KO:K06111]
112968053  EXOC2; exocyst complex component 2 isoform X1 [KO:K17637]
112973746  RALA; ras-related protein Ral-A [KO:K07834]
112966901  ACTG1; actin, cytoplasmic 2 [KO:K05692]
112967343  actin, cytoplasmic type 5 [KO:K05692]
112974241  ACTB; actin, cytoplasmic 1 [KO:K05692]
112974561  S100A10; protein S100-A10 [KO:K17274]
112962825  ANXA2; annexin A2 [KO:K17092]
112976899  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
112965780  rho guanine nucleotide exchange factor 26-like [KO:K13744]
112966247  rho-related GTP-binding protein RhoG-like [KO:K07863]
112978636  RHOG; rho-related GTP-binding protein RhoG [KO:K07863]
112976552  engulfment and cell motility protein 1 [KO:K12366]
112974603  engulfment and cell motility protein 1-like [KO:K12366]
112977274  ELMO2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
112972425  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
112962520  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
112972073  MYL5; myosin light chain 5 [KO:K12753]
112971209  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
112968470  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
112965010  MYL10; myosin regulatory light chain 10 [KO:K12756]
112968356  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
112968357  myosin regulatory light chain 2, smooth muscle minor isoform-like [KO:K12757]
112961581  LOW QUALITY PROTEIN: myosin regulatory light chain 2, skeletal muscle isoform-like [KO:K12758]
112973298  FHOD1; FH1/FH2 domain-containing protein 1 [KO:K23938]
112966852  CDC42; cell division control protein 42 homolog [KO:K04393]
112974255  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
112975375  NCKAP1L; nck-associated protein 1-like [KO:K05750]
112977988  NCKAP1; nck-associated protein 1 [KO:K05750]
112964742  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
112976972  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
112974813  abl interactor 1 isoform X1 [KO:K23649]
112975189  BRK1; protein BRICK1 [KO:K05752]
112975801  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
112960481  WASF3; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
112973164  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
112977084  ACTR3; actin-related protein 3 [KO:K18584]
112978287  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
112974332  ARPC1A; actin-related protein 2/3 complex subunit 1A isoform X1 [KO:K05757]
112974377  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
112971999  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
112962487  ARPC3; actin-related protein 2/3 complex subunit 3 isoform X1 [KO:K05756]
112976624  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
112964596  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
112977449  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
112972081  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
112975771  PAK3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
112972565  unconventional myosin-VI [KO:K10358]
112963723  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
112970036  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
112972913  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
112962649  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1 [KO:K21289] [EC:2.7.1.153]
112971594  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
112972435  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
112966611  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
112974382  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
112974780  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
112969337  CYTH4; LOW QUALITY PROTEIN: cytohesin-4 [KO:K18441]
112961198  ARF6; ADP-ribosylation factor 6 [KO:K07941]
112977379  ARF1; ADP-ribosylation factor 1 isoform X1 [KO:K07937]
112964505  SNX18; sorting nexin-18 [KO:K17923]
112971544  SNX9; sorting nexin-9 isoform X1 [KO:K17923]
112967240  SNX33; sorting nexin-33 isoform X1 [KO:K17923]
112960474  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
112965426  DNM2; dynamin-2 isoform X1 [KO:K23484] [EC:3.6.5.5]
112975355  toll-like receptor 10 [KO:K10169]
112976729  toll-like receptor 2 type-2 isoform X1 [KO:K10159]
112976730  toll-like receptor 2 type-2 isoform X1 [KO:K10159]
112967647  toll-like receptor 2 type-2 [KO:K10159]
112968910  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
112978275  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
112963054  TLR4; toll-like receptor 4 isoform X1 [KO:K10160]
112961280  LY96; lymphocyte antigen 96 isoform X1 [KO:K05400]
112961102  TLR5; toll-like receptor 5 [KO:K10168]
112976393  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
112960908  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
112963613  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
112965723  TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
112974544  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
112967666  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
112977217  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
112962239  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
112974186  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
112977918  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
112972215  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
112967142  NOD1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
112972749  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
112973400  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
112961507  HSP90B1; endoplasmin isoform X1 [KO:K09487]
112964082  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
112961084  receptor-interacting serine/threonine-protein kinase 2-like [KO:K08846] [EC:2.7.11.1]
112975495  CSE1L; exportin-2 isoform X1 [KO:K18423]
112963948  KPNA1; importin subunit alpha-5 isoform X1 [KO:K23940]
112970705  KPNA3; importin subunit alpha-4 isoform X1 [KO:K23583]
112961956  KPNA4; importin subunit alpha-3 isoform X1 [KO:K23583]
112974063  RPS3; 40S ribosomal protein S3 isoform X1 [KO:K02985]
112962697  HRAS; GTPase HRas [KO:K02833]
112966394  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
112970007  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
112972305  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
112978378  MAPK1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
112974370  dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
112966967  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
112961437  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
112961439  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
112973525  MAPK11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
112973531  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
112970862  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
112964469  uncharacterized protein LOC112964469 [KO:K04431] [EC:2.7.12.2]
112963855  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
112964950  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
112967355  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
112960526  FOS; proto-oncogene c-Fos [KO:K04379]
112967663  JUN; transcription factor AP-1 [KO:K04448]
112975327  interleukin-1 beta-like isoform X1 [KO:K04519]
112974163  IL6; interleukin-6 [KO:K05405]
112977596  interleukin-8-like [KO:K10030]
112977599  platelet factor 4-like [KO:K10030]
112977640  interleukin-8-like [KO:K10030]
112973716  CTNNB1; catenin beta-1 [KO:K02105]
112964702  TCF7; transcription factor 7 isoform X1 [KO:K02620]
112971101  TCF7L1; transcription factor 7-like 1 [KO:K04490]
112967920  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
112972206  LEF1; lymphoid enhancer-binding factor 1 [KO:K04492]
112971811  MYC; myc proto-oncogene protein [KO:K04377]
112967312  FBXO22; F-box only protein 22 [KO:K10302]
112964703  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
112965943  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
112969740  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
112976683  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
112971955  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
112968039  RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
112977650  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
112964213  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
112973657  tumor necrosis factor receptor superfamily member 10B-like [KO:K04722]
112972388  tumor necrosis factor receptor superfamily member 6-like [KO:K04722]
112977257  FADD; FAS-associated death domain protein [KO:K02373]
112976408  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
112976426  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
112961412  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
112970720  cytochrome c, somatic-like [KO:K08738]
112966553  cytochrome c [KO:K08738]
112972797  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
112974750  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
112968031  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
112966529  RHOB; rho-related GTP-binding protein RhoB [KO:K07856]
112976653  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
112970977  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112960994  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112973733  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112976875  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
112963989  thioredoxin isoform X1 [KO:K03671]
112971479  TXN2; thioredoxin, mitochondrial [KO:K03671]
112966225  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
112965025  caspase-1-like isoform X1 [KO:K01370] [EC:3.4.22.36]
112967461  IL18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
arow04010  MAPK signaling pathway
arow04210  Apoptosis
arow04217  Necroptosis
arow04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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