Entry |
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Name |
Regulation of actin cytoskeleton - Chelonoidis abingdonii (Abingdon island giant tortoise) |
Class |
Cellular Processes; Cell motility
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Pathway map |
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Other DBs |
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Organism |
Chelonoidis abingdonii (Abingdon island giant tortoise) [GN: cabi]
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Gene |
116834788 | FGF2; LOW QUALITY PROTEIN: fibroblast growth factor 2 [KO:K18497] |
116819340 | PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359] |
116832904 | CHRM3; muscarinic acetylcholine receptor M3 isoform X1 [KO:K04131] |
116821706 | CHRM4; muscarinic acetylcholine receptor M4 isoform X1 [KO:K04132] |
116816726 | GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346] |
116822478 | GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639] |
116817748 | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [KO:K04347] |
116819872 | GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347] |
116823931 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720] |
116838738 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 [KO:K05722] |
116831920 | BCAR1; breast cancer anti-estrogen resistance protein 1 [KO:K05726] |
116820589 | ARHGEF6; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 6 [KO:K05729] |
116819437 | PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153] |
116826683 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
116821938 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
116839230 | phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649] |
116839322 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649] |
116826231 | PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649] |
116817428 | VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730] |
116838491 | VAV3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730] |
116835433 | TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731] |
116828343 | ARHGAP35; rho GTPase-activating protein 35 isoform X1 [KO:K05732] |
116815824 | RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861] |
116817598 | CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393] |
116816044 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710] |
116833423 | PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16] |
116835801 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270] |
116831705 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X1 [KO:K12329] |
116834895 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C [KO:K17457] |
116836760 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351] |
116815096 | MYL7; myosin regulatory light chain 2, atrial isoform isoform X1 [KO:K12754] |
116825892 | myosin regulatory light chain 2B, cardiac muscle isoform [KO:K12756] |
116830662 | myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757] |
116835956 | myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758] |
116834889 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627] |
116834911 | brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627] |
116818134 | WASL; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612] |
116838018 | WASF2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748] |
116822322 | CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749] |
116836697 | CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749] |
116821450 | WASF1; wiskott-Aldrich syndrome protein family member 1 [KO:K05753] |
116815779 | ARPC2; actin-related protein 2/3 complex subunit 2 isoform X1 [KO:K05758] |
116817443 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein isoform X1 [KO:K05754] |
116818044 | IQGAP1; ras GTPase-activating-like protein IQGAP1 isoform X1 [KO:K16848] |
116821262 | IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform X1 [KO:K05767] |
116819325 | SPATA13; spermatogenesis-associated protein 13 isoform X1 [KO:K05769] |
116815945 | ARHGEF4; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 4 [KO:K05769] |
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Compound |
C00681 | 1-Acyl-sn-glycerol 3-phosphate |
C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
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Reference |
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Authors |
Burridge K, Wennerberg K. |
Title |
Rho and Rac take center stage. |
Journal |
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Reference |
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Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
Title |
Rho GTPases: signaling, migration, and invasion. |
Journal |
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Reference |
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Authors |
Takai Y, Sasaki T, Matozaki T. |
Title |
Small GTP-binding proteins. |
Journal |
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Reference |
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Authors |
Pollard TD. |
Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
Journal |
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Reference |
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Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
Title |
Cell migration: integrating signals from front to back. |
Journal |
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Reference |
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Authors |
Sastry SK, Burridge K. |
Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
Journal |
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Reference |
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Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
Title |
Cell adhesion and Rho small GTPases. |
Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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KO pathway |
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LinkDB |
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