KEGG   PATHWAY: cang05168
Entry
cang05168                   Pathway                                
Name
Herpes simplex virus 1 infection - Colobus angolensis palliatus (Angola colobus)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
cang05168  Herpes simplex virus 1 infection
cang05168

Organism
Colobus angolensis palliatus (Angola colobus) [GN:cang]
Gene
105513727  LTA; lymphotoxin-alpha [KO:K05468]
105512892  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
105503883  TNFRSF14; tumor necrosis factor receptor superfamily member 14 [KO:K05152]
105522700  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
105509216  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
105525125  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
105507149  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
105527033  IKBKG; NF-kappa-B essential modulator [KO:K07210]
105500419  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
105512675  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
105512156  RELA; transcription factor p65 [KO:K04735]
105500933  BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
105500934  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
105508744  CCL2; C-C motif chemokine 2 [KO:K14624]
105501130  PVRL1; nectin-1 isoform X1 [KO:K06081]
105526985  nectin-2 [KO:K06531]
105513087  paired immunoglobulin-like type 2 receptor alpha isoform X1 [KO:K15411]
105502317  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [KO:K07293] [EC:3.1.3.48]
105503537  ITGA5; integrin alpha-5 [KO:K06484]
105526547  ITGB3; integrin beta-3 [KO:K06493]
105502517  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
105516007  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
105522713  CARD9; caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
105514764  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
105503452  IFNB1; interferon beta [KO:K05415]
105523626  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
105512957  C3; complement C3 [KO:K03990]
105501454  C5; complement C5 [KO:K03994]
105509475  CFP; properdin [KO:K15412]
105524473  toll-like receptor 2 [KO:K10159]
105523823  TLR9; toll-like receptor 9 [KO:K10161]
105519819  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
105503197  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
105524325  TLR3; toll-like receptor 3 [KO:K05401]
105512851  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
105507588  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
105521650  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
105510802  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
105511739  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
105527764  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
105515555  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
105519632  IL1B; interleukin-1 beta isoform X1 [KO:K04519]
105518754  CCL5; C-C motif chemokine 5 [KO:K12499]
105513330  IL6; interleukin-6 isoform X1 [KO:K05405]
105513728  TNF; tumor necrosis factor [KO:K03156]
105523976  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
105515783  IL12B; interleukin-12 subunit beta [KO:K05425]
105516444  DDX58; probable ATP-dependent RNA helicase DDX58 [KO:K12646] [EC:5.6.2.6]
105515310  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
105512800  MAVS; mitochondrial antiviral-signaling protein [KO:K12648]
105518439  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
105509453  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
105502730  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
105503436  interferon alpha-1/13 [KO:K05414]
105503438  IFNA8; interferon alpha-8 [KO:K05414]
105503439  IFNA2; interferon alpha-2 [KO:K05414]
105503440  interferon alpha-1/13-like [KO:K05414]
105503441  interferon alpha-1/13-like [KO:K05414]
105503442  interferon alpha-6 [KO:K05414]
105503444  IFNA14; interferon alpha-14 [KO:K05414]
105503445  interferon alpha-4 [KO:K05414]
105503446  interferon alpha-4-like [KO:K05414]
105503447  interferon alpha-17-like [KO:K05414]
105503449  interferon alpha-10 [KO:K05414]
105513551  MB21D1; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
105506995  TMEM173; stimulator of interferon genes protein [KO:K12654]
105521930  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
105512325  PPP1CA; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
105507823  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
105506324  EIF2AK1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 2-alpha kinase 1 [KO:K16194] [EC:2.7.11.1]
105507534  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
105519668  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
105505031  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [KO:K16196] [EC:2.7.11.1]
105517246  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
105516298  EIF2B1; translation initiation factor eIF-2B subunit alpha isoform X1 [KO:K03239]
105517146  EIF2B2; translation initiation factor eIF-2B subunit beta [KO:K03754]
105515359  EIF2B3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
105517228  EIF2B4; translation initiation factor eIF-2B subunit delta isoform X1 [KO:K03680]
105514471  EIF2B5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
105502273  OAS1; 2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
105502274  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
105502275  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
105511900  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
105521632  HCFC1; host cell factor 1 isoform X1 [KO:K14966]
105508141  HCFC2; host cell factor 2 [KO:K27390]
105501135  POU2F3; POU domain, class 2, transcription factor 3 isoform X1 [KO:K09364]
105505535  POU2F1; POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
105507856  POU2F2; POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
105524762  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
105524754  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
105521309  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
105510845  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
105520874  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
105507777  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
105500610  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
105503733  IRF9; interferon regulatory factor 9 isoform X1 [KO:K04693]
105501500  ZNF169; zinc finger protein 169 isoform X1 [KO:K09228]
105501509  ZNF658; zinc finger protein 658 isoform X1 [KO:K09228]
105501540  zinc finger protein 484 [KO:K09228]
105501549  ZNF782; LOW QUALITY PROTEIN: zinc finger protein 782 [KO:K09228]
105508046  zinc finger protein 141 [KO:K09228]
105508047  zinc finger protein 595 isoform X1 [KO:K09228]
105508060  zinc finger protein 721-like [KO:K09228]
105508061  LOW QUALITY PROTEIN: zinc finger protein 732-like [KO:K09228]
105514818  zinc finger protein 883 [KO:K09228]
105514822  zinc finger protein 813-like [KO:K09228]
105514824  zinc finger protein 813-like [KO:K09228]
105514825  ZNF765; zinc finger protein 765 [KO:K09228]
105514829  LOW QUALITY PROTEIN: zinc finger protein 813-like [KO:K09228]
105514833  LOW QUALITY PROTEIN: zinc finger protein 611-like [KO:K09228]
105514834  LOW QUALITY PROTEIN: zinc finger protein 83-like [KO:K09228]
105514837  ZNF649; zinc finger protein 649 [KO:K09228]
105514891  ZNF114; zinc finger protein 114 [KO:K09228]
105522032  zinc finger protein OZF-like [KO:K09228]
105522046  LOW QUALITY PROTEIN: zinc finger protein 431-like [KO:K09228]
105522047  ZNF429; zinc finger protein 429 [KO:K09228]
105522050  ZNF100; zinc finger protein 100 [KO:K09228]
105522051  ZNF708; LOW QUALITY PROTEIN: zinc finger protein 708 [KO:K09228]
105522052  ZNF43; zinc finger protein 43 [KO:K09228]
105522053  LOW QUALITY PROTEIN: zinc finger protein 257-like [KO:K09228]
105522094  ZNF514; zinc finger protein 514 [KO:K09228]
105522097  ZNF2; zinc finger protein 2 isoform X1 [KO:K09228]
105501585  zinc finger protein 85-like [KO:K09228]
105501851  zinc finger protein 92 isoform X1 [KO:K09228]
105508643  ZNF596; zinc finger protein 596 [KO:K09228]
105508709  LOW QUALITY PROTEIN: zinc finger protein 484-like [KO:K09228]
105515677  ZNF181; zinc finger protein 181 isoform X1 [KO:K09228]
105522203  zinc finger protein 501-like [KO:K09228]
105502142  ZNF713; zinc finger protein 713 [KO:K09228]
105502400  ZNF334; zinc finger protein 334 isoform X1 [KO:K09228]
105508954  ZNF250; zinc finger protein 250 isoform X1 [KO:K09228]
105508955  zinc finger protein 517 isoform X1 [KO:K09228]
105508959  ZNF34; zinc finger protein 34 isoform X1 [KO:K09228]
105508960  ZNF251; zinc finger protein 251 isoform X1 [KO:K09228]
105508991  ZNF707; zinc finger protein 707 isoform X1 [KO:K09228]
105508993  ZNF623; zinc finger protein 623 [KO:K09228]
105515707  LOW QUALITY PROTEIN: zinc finger protein 181-like [KO:K09228]
105515718  ZNF599; zinc finger protein 599 [KO:K09228]
105515732  ZNF30; LOW QUALITY PROTEIN: zinc finger protein 30 [KO:K09228]
105515740  ZNF792; zinc finger protein 792 [KO:K09228]
105522769  zinc finger protein 133 [KO:K09228]
105502588  putative zinc finger protein 840 [KO:K09228]
105509455  ZNF674; zinc finger protein 674 isoform X1 [KO:K09228]
105509470  ZNF157; zinc finger protein 157 [KO:K09228]
105509471  ZNF41; zinc finger protein 41 [KO:K09228]
105509482  ZNF81; zinc finger protein 81 [KO:K09228]
105509483  ZNF182; zinc finger protein 182 [KO:K09228]
105509485  ZNF630; zinc finger protein 630 isoform X1 [KO:K09228]
105516512  ZNF565; zinc finger protein 565 isoform X1 [KO:K09228]
105523178  ZNF624; zinc finger protein 624 [KO:K09228]
105523258  zinc finger protein 254-like [KO:K09228]
105503252  ZNF195; LOW QUALITY PROTEIN: zinc finger protein 195 [KO:K09228]
105503310  zinc finger protein 506 [KO:K09228]
105524017  ZNF8; zinc finger protein 8 [KO:K09228]
105524020  ZNF544; zinc finger protein 544 [KO:K09228]
105524024  ZNF584; zinc finger protein 584 isoform X1 [KO:K09228]
105524026  ZNF132; zinc finger protein 132 [KO:K09228]
105524028  zinc finger protein 324B [KO:K09228]
105524058  ZNF74; zinc finger protein 74 isoform X1 [KO:K09228]
105517609  ZSCAN32; zinc finger and SCAN domain-containing protein 32 isoform X1 [KO:K09228]
105517619  ZNF205; zinc finger protein 205 [KO:K09228]
105517870  ZNF461; zinc finger protein 461 isoform X1 [KO:K09228]
105517871  ZNF529; zinc finger protein 529 isoform X1 [KO:K09228]
105517874  ZNF382; zinc finger protein 382 isoform X1 [KO:K09228]
105517876  ZNF566; zinc finger protein 566 isoform X1 [KO:K09228]
105517879  ZFP82; zinc finger protein 82 homolog [KO:K09228]
105517880  ZFP14; zinc finger protein 14 homolog isoform X1 [KO:K09228]
105517881  ZNF790; zinc finger protein 790 isoform X1 [KO:K09228]
105517884  ZNF829; zinc finger protein 829 isoform X1 [KO:K09228]
105517887  zinc finger protein 461-like [KO:K09228]
105517889  ZNF568; zinc finger protein 568 isoform X1 [KO:K09228]
105517890  ZNF420; zinc finger protein 420 isoform X1 [KO:K09228]
105517891  ZNF585A; zinc finger protein 585A isoform X1 [KO:K09228]
105517892  ZNF585B; zinc finger protein 585B isoform X1 [KO:K09228]
105504081  ZNF79; zinc finger protein 79 isoform X1 [KO:K09228]
105504242  ZNF300; zinc finger protein 300 isoform X1 [KO:K09228]
105511286  ZNF786; zinc finger protein 786 isoform X1 [KO:K09228]
105511287  ZNF425; zinc finger protein 425 [KO:K09228]
105511288  zinc finger protein 282 [KO:K09228]
105511290  ZNF398; zinc finger protein 398 [KO:K09228]
105511291  ZNF212; zinc finger protein 212 [KO:K09228]
105511294  ZNF777; zinc finger protein 777 isoform X1 [KO:K09228]
105511457  ZNF783; protein ZNF783 [KO:K09228]
105511460  ZNF746; zinc finger protein 746 [KO:K09228]
105518022  ZNF850; zinc finger protein 850 [KO:K09228]
105518023  ZNF567; zinc finger protein 567 [KO:K09228]
105518082  ZNF619; zinc finger protein 619 isoform X1 [KO:K09228]
105518083  ZNF621; zinc finger protein 621 isoform X1 [KO:K09228]
105518084  ZNF620; zinc finger protein 620 isoform X1 [KO:K09228]
105518112  ZNF662; LOW QUALITY PROTEIN: zinc finger protein 662 [KO:K09228]
105518148  ZNF189; zinc finger protein 189 isoform X1 [KO:K09228]
105524765  ZNF454; zinc finger protein 454 isoform X1 [KO:K09228]
105524766  ZNF879; zinc finger protein 879 [KO:K09228]
105524768  ZNF354C; zinc finger protein 354C [KO:K09228]
105524772  ZNF354B; zinc finger protein 354B isoform X1 [KO:K09228]
105524966  ZNF551; zinc finger protein 551 [KO:K09228]
105524967  ZNF671; zinc finger protein 671 [KO:K09228]
105524968  ZNF154; zinc finger protein 154 [KO:K09228]
105524969  ZNF776; zinc finger protein 776 isoform X1 [KO:K09228]
105524970  ZNF586; zinc finger protein 586 isoform X1 [KO:K09228]
105524971  ZNF814; LOW QUALITY PROTEIN: putative uncharacterized zinc finger protein 814 [KO:K09228]
105524972  zinc finger protein 587 isoform X1 [KO:K09228]
105524973  ZNF418; zinc finger protein 418 [KO:K09228]
105524974  ZNF256; zinc finger protein 256 [KO:K09228]
105524976  ZNF606; zinc finger protein 606 [KO:K09228]
105524978  ZNF135; zinc finger protein 135 isoform X1 [KO:K09228]
105504533  ZFP90; zinc finger protein 90 homolog isoform X1 [KO:K09228]
105504803  ZNF530; zinc finger protein 530 [KO:K09228]
105504804  ZIK1; zinc finger protein interacting with ribonucleoprotein K isoform X1 [KO:K09228]
105504806  ZNF416; zinc finger protein 416 isoform X1 [KO:K09228]
105504807  ZNF549; zinc finger protein 549 isoform X1 [KO:K09228]
105504808  ZNF550; zinc finger protein 550 [KO:K09228]
105504809  ZNF749; LOW QUALITY PROTEIN: zinc finger protein 749 [KO:K09228]
105504810  ZNF772; LOW QUALITY PROTEIN: zinc finger protein 772 [KO:K09228]
105504811  ZNF773; zinc finger protein 773 isoform X1 [KO:K09228]
105504813  ZNF548; zinc finger protein 548 isoform X1 [KO:K09228]
105504814  ZNF17; zinc finger protein 17 isoform X1 [KO:K09228]
105504816  ZNF547; zinc finger protein 547 [KO:K09228]
105504817  ZNF304; zinc finger protein 304 isoform X1 [KO:K09228]
105504819  ZNF543; zinc finger protein 543 [KO:K09228]
105504820  ZNF460; zinc finger protein 460 isoform X1 [KO:K09228]
105504821  ZNF264; zinc finger protein 264 isoform X1 [KO:K09228]
105504830  ZNF71; endothelial zinc finger protein induced by tumor necrosis factor alpha isoform X1 [KO:K09228]
105504831  ZNF470; zinc finger protein 470 [KO:K09228]
105504832  ZFP28; zinc finger protein 28 homolog [KO:K09228]
105504834  ZNF471; zinc finger protein 471 [KO:K09228]
105504835  ZNF667; zinc finger protein 667 [KO:K09228]
105504837  ZNF583; zinc finger protein 583 isoform X1 [KO:K09228]
105504839  LOW QUALITY PROTEIN: zinc finger protein OZF-like [KO:K09228]
105504840  ZNF582; zinc finger protein 582 isoform X1 [KO:K09228]
105511489  zinc finger protein 133-like [KO:K09228]
105511711  ZFP37; zinc finger protein 37 homolog [KO:K09228]
105525237  ZNF25; zinc finger protein 25 [KO:K09228]
105525239  LOW QUALITY PROTEIN: zinc finger protein 33A-like [KO:K09228]
105525241  zinc finger protein 33B isoform X1 [KO:K09228]
105525240  ZNF605; zinc finger protein 605 isoform X1 [KO:K09228]
105525242  ZNF248; zinc finger protein 248 isoform X1 [KO:K09228]
105525247  zinc finger protein 25-like [KO:K09228]
105525246  ZNF26; zinc finger protein 26 isoform X1 [KO:K09228]
105525258  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
105525267  ZNF84; zinc finger protein 84 [KO:K09228]
105525277  ZNF140; zinc finger protein 140 isoform X1 [KO:K09228]
105525305  ZNF891; zinc finger protein 891 [KO:K09228]
105525315  ZNF10; zinc finger protein 10 isoform X1 [KO:K09228]
105525332  ZNF268; zinc finger protein 268 isoform X1 [KO:K09228]
105504911  ZNF211; zinc finger protein 211 [KO:K09228]
105504914  zinc finger protein 419-like [KO:K09228]
105504917  ZIM3; zinc finger imprinted 3 [KO:K09228]
105505193  zinc finger protein 430 isoform X1 [KO:K09228]
105505195  LOW QUALITY PROTEIN: putative zinc finger protein 66 [KO:K09228]
105505197  ZNF85; zinc finger protein 85 isoform X1 [KO:K09228]
105505198  zinc finger protein 737 [KO:K09228]
105505200  LOW QUALITY PROTEIN: zinc finger protein 626-like [KO:K09228]
105505201  zinc finger protein 93-like [KO:K09228]
105505203  ZNF682; zinc finger protein 682 isoform X1 [KO:K09228]
105505225  zinc finger protein 486-like [KO:K09228]
105505226  zinc finger protein 682-like [KO:K09228]
105519001  ZNF337; zinc finger protein 337 [KO:K09228]
105519106  ZNF527; zinc finger protein 527 isoform X1 [KO:K09228]
105519108  HKR1; LOW QUALITY PROTEIN: Krueppel-related zinc finger protein 1 [KO:K09228]
105519109  ZNF383; zinc finger protein 383 [KO:K09228]
105519110  ZNF569; zinc finger protein 569 isoform X1 [KO:K09228]
105519111  ZNF793; zinc finger protein 793 [KO:K09228]
105519112  ZFP30; zinc finger protein 30 homolog [KO:K09228]
105519114  ZNF540; zinc finger protein 540 isoform X1 [KO:K09228]
105519115  ZNF571; zinc finger protein 571 [KO:K09228]
105519117  ZNF573; zinc finger protein 573 isoform X1 [KO:K09228]
105519119  ZNF607; zinc finger protein 607 isoform X1 [KO:K09228]
105519172  ZNF780B; zinc finger protein 780B [KO:K09228]
105519173  ZNF780A; zinc finger protein 780A isoform X1 [KO:K09228]
105525777  ZNF860; LOW QUALITY PROTEIN: zinc finger protein 860 [KO:K09228]
105526042  ZNF19; zinc finger protein 19 isoform X1 [KO:K09228]
105526063  ZNF23; zinc finger protein 23 isoform X1 [KO:K09228]
105505395  LOW QUALITY PROTEIN: zinc finger protein 721-like [KO:K09228]
105505397  ZNF286A; zinc finger protein 286A isoform X1 [KO:K09228]
105505677  ZNF768; zinc finger protein 768 [KO:K09228]
105505679  ZNF785; LOW QUALITY PROTEIN: zinc finger protein 785 [KO:K09228]
105505680  ZNF689; zinc finger protein 689 [KO:K09228]
105505726  zinc finger protein 764 [KO:K09228]
105512663  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
105512766  ZNF343; zinc finger protein 343 isoform X1 [KO:K09228]
105519233  ZNF546; LOW QUALITY PROTEIN: zinc finger protein 546 [KO:K09228]
105519550  ZNF354A; zinc finger protein 354A [KO:K09228]
105526270  zinc finger protein 492-like [KO:K09228]
105526271  LOW QUALITY PROTEIN: zinc finger protein 729-like [KO:K09228]
105526554  LOW QUALITY PROTEIN: zinc finger protein 257-like [KO:K09228]
105526556  zinc finger protein 708-like [KO:K09228]
105506119  zinc finger protein 480 [KO:K09228]
105512897  ZNF557; zinc finger protein 557 isoform X1 [KO:K09228]
105513074  ZNF3; zinc finger protein 3 isoform X1 [KO:K09228]
105519757  ZNF333; zinc finger protein 333 isoform X1 [KO:K09228]
105519797  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
105519960  ZNF675; zinc finger protein 675 isoform X1 [KO:K09228]
105519961  putative zinc finger protein 724 isoform X1 [KO:K09228]
105519964  ZNF681; zinc finger protein 681 isoform X1 [KO:K09228]
105519968  ZNF730; LOW QUALITY PROTEIN: putative zinc finger protein 730 [KO:K09228]
105519969  LOW QUALITY PROTEIN: zinc finger protein 254-like [KO:K09228]
105519972  ZNF91; LOW QUALITY PROTEIN: zinc finger protein 91 [KO:K09228]
105519999  zinc finger protein 431 [KO:K09228]
105520007  zinc finger protein 431-like [KO:K09228]
105526914  ZNF180; zinc finger protein 180 isoform X1 [KO:K09228]
105526915  ZNF285; zinc finger protein 285 isoform X1 [KO:K09228]
105526917  ZNF229; LOW QUALITY PROTEIN: zinc finger protein 229 [KO:K09228]
105526918  ZNF112; zinc finger protein 112 isoform X1 [KO:K09228]
105526919  ZNF227; zinc finger protein 227 isoform X1 [KO:K09228]
105526920  ZNF233; LOW QUALITY PROTEIN: zinc finger protein 233 [KO:K09228]
105526921  ZNF235; zinc finger protein 235 isoform X1 [KO:K09228]
105526922  ZNF226; zinc finger protein 226 isoform X1 [KO:K09228]
105526924  ZNF224; zinc finger protein 224 isoform X1 [KO:K09228]
105526926  ZNF234; zinc finger protein 234 [KO:K09228]
105526927  ZNF223; zinc finger protein 223 isoform X1 [KO:K09228]
105526928  ZNF284; zinc finger protein 284 [KO:K09228]
105526929  ZNF230; zinc finger protein 230 isoform X1 [KO:K09228]
105526930  ZNF155; zinc finger protein 155 isoform X1 [KO:K09228]
105526932  ZNF45; zinc finger protein 45 [KO:K09228]
105526934  ZNF283; zinc finger protein 283 isoform X1 [KO:K09228]
105526991  ZNF222; zinc finger protein 222 [KO:K09228]
105526992  ZNF221; zinc finger protein 221 [KO:K09228]
105520075  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
105520181  ZNF485; zinc finger protein 485 [KO:K09228]
105527067  LOW QUALITY PROTEIN: zinc finger protein 253-like [KO:K09228]
105527069  ZNF93; zinc finger protein 93 [KO:K09228]
105500280  ZNF92; LOW QUALITY PROTEIN: zinc finger protein 92 [KO:K09228]
105500283  LOW QUALITY PROTEIN: zinc finger protein 85-like [KO:K09228]
105500284  ZNF107; zinc finger protein 107 [KO:K09228]
105500288  ZNF273; zinc finger protein 273 [KO:K09228]
105513830  ZFP57; zinc finger protein 57 homolog [KO:K09228]
105513846  ZNF311; zinc finger protein 311 isoform X1 [KO:K09228]
105513895  ZNF184; zinc finger protein 184 [KO:K09228]
105520554  ZNF214; zinc finger protein 214 isoform X1 [KO:K09228]
105520807  ZNF791; zinc finger protein 791 isoform X1 [KO:K09228]
105520808  ZNF490; zinc finger protein 490 [KO:K09228]
105520809  ZNF564; zinc finger protein 564 isoform X1 [KO:K09228]
105520810  ZNF799; LOW QUALITY PROTEIN: zinc finger protein 799 [KO:K09228]
105520811  ZNF442; zinc finger protein 442 isoform X1 [KO:K09228]
105520812  zinc finger protein 563 isoform X1 [KO:K09228]
105520813  ZNF44; zinc finger protein 44 isoform X1 [KO:K09228]
105520816  zinc finger protein ZnFP12 [KO:K09228]
105520818  ZNF136; zinc finger protein 136 isoform X1 [KO:K09228]
105520819  ZNF20; zinc finger protein 20 isoform X1 [KO:K09228]
105520821  zinc finger protein 700-like [KO:K09228]
105520822  ZNF433; LOW QUALITY PROTEIN: zinc finger protein 433 [KO:K09228]
105520823  zinc finger protein 69 [KO:K09228]
105520824  ZNF441; zinc finger protein 441 [KO:K09228]
105520825  ZNF823; zinc finger protein 823 isoform X1 [KO:K09228]
105520826  ZNF627; zinc finger protein 627 isoform X1 [KO:K09228]
105527485  LOW QUALITY PROTEIN: zinc finger protein 254-like [KO:K09228]
105527487  LOW QUALITY PROTEIN: zinc finger protein 254-like [KO:K09228]
105527576  LOW QUALITY PROTEIN: zinc finger protein 85-like [KO:K09228]
105527577  zinc finger protein 676-like [KO:K09228]
105527656  ZNF554; zinc finger protein 554 [KO:K09228]
105527657  ZNF57; zinc finger protein 57 [KO:K09228]
105527700  ZNF555; zinc finger protein 555 [KO:K09228]
105527702  ZNF556; zinc finger protein 556 [KO:K09228]
105527703  ZNF77; zinc finger protein 77 [KO:K09228]
105500386  ZNF101; zinc finger protein 101 [KO:K09228]
105500387  ZNF14; zinc finger protein 14 [KO:K09228]
105500388  ZNF506; zinc finger protein 506 [KO:K09228]
105500417  zinc finger protein 101-like [KO:K09228]
105500454  zinc finger protein 92-like [KO:K09228]
105500632  zinc finger protein 138-like [KO:K09228]
105514289  ZNF436; zinc finger protein 436 [KO:K09228]
105514365  zinc finger protein 570 [KO:K09228]
105520893  ZNF846; LOW QUALITY PROTEIN: zinc finger protein 846 [KO:K09228]
105520894  ZNF561; zinc finger protein 561 isoform X1 [KO:K09228]
105520895  ZNF562; zinc finger protein 562 [KO:K09228]
105520896  ZNF121; zinc finger protein 121 isoform X1 [KO:K09228]
105520897  ZNF266; zinc finger protein 266 isoform X1 [KO:K09228]
105520902  ZNF560; zinc finger protein 560 [KO:K09228]
105520904  ZNF426; LOW QUALITY PROTEIN: zinc finger protein 426 [KO:K09228]
105520905  ZNF177; zinc finger protein 177 [KO:K09228]
105520906  ZNF559; zinc finger protein 559 isoform X1 [KO:K09228]
105520907  ZNF699; zinc finger protein 699 [KO:K09228]
105520911  ZNF317; zinc finger protein 317 isoform X1 [KO:K09228]
105520915  ZNF558; zinc finger protein 558 isoform X1 [KO:K09228]
105520929  zinc finger protein 625 [KO:K09228]
105520931  zinc finger protein 788-like [KO:K09228]
105520932  ZNF878; LOW QUALITY PROTEIN: zinc finger protein 878 [KO:K09228]
105520933  LOW QUALITY PROTEIN: zinc finger protein 69-like [KO:K09228]
105520934  zinc finger protein 709-like [KO:K09228]
105521073  ZNF679; zinc finger protein 679 [KO:K09228]
105521077  zinc finger protein 736 [KO:K09228]
105521079  ZNF680; zinc finger protein 680 isoform X1 [KO:K09228]
105521085  LOW QUALITY PROTEIN: putative zinc finger protein 735 [KO:K09228]
105521148  ZFP69; zinc finger protein ZFP69 isoform X1 [KO:K09228]
105521149  ZFP69B; zinc finger protein ZFP69B isoform X1 [KO:K09228]
105521157  ZNF684; zinc finger protein 684 [KO:K09228]
105500861  LOW QUALITY PROTEIN: zinc finger protein 658-like [KO:K09228]
105500862  LOW QUALITY PROTEIN: zinc finger protein 705A-like [KO:K09228]
105507658  ZNF641; zinc finger protein 641 isoform X1 [KO:K09228]
105514572  ZFP1; zinc finger protein 1 homolog isoform X1 [KO:K09228]
105514646  ZNF331; zinc finger protein 331 [KO:K09228]
105514648  LOW QUALITY PROTEIN: zinc finger protein 813-like [KO:K09228]
105514650  zinc finger protein 813 [KO:K09228]
105514651  zinc finger protein 845 [KO:K09228]
105514652  zinc finger protein 83-like [KO:K09228]
105514653  ZNF83; zinc finger protein 83 [KO:K09228]
105514654  ZNF611; zinc finger protein 611 isoform X1 [KO:K09228]
105514655  zinc finger protein 600 [KO:K09228]
105514657  ZNF28; zinc finger protein 28 [KO:K09228]
105514658  zinc finger protein 28 isoform X1 [KO:K09228]
105514660  zinc finger protein 320 [KO:K09228]
105514661  ZNF888; zinc finger protein 888 isoform X1 [KO:K09228]
105514663  ZNF816; zinc finger protein 816 [KO:K09228]
105514664  zinc finger protein 701-like [KO:K09228]
105514668  ZNF160; zinc finger protein 160 isoform X1 [KO:K09228]
105514669  ZNF415; zinc finger protein 415 [KO:K09228]
105514670  ZNF347; zinc finger protein 347 isoform X1 [KO:K09228]
105514672  ZNF665; zinc finger protein 665 [KO:K09228]
105514676  LOW QUALITY PROTEIN: zinc finger protein 468-like [KO:K09228]
105514677  ZNF534; LOW QUALITY PROTEIN: zinc finger protein 534 [KO:K09228]
105514679  ZNF528; zinc finger protein 528 isoform X1 [KO:K09228]
105514680  ZNF610; zinc finger protein 610 isoform X1 [KO:K09228]
105514681  ZNF880; zinc finger protein 880 [KO:K09228]
105514682  ZNF766; zinc finger protein 766 isoform X1 [KO:K09228]
105514684  ZNF614; LOW QUALITY PROTEIN: zinc finger protein 614 [KO:K09228]
105514685  ZNF616; zinc finger protein 616 [KO:K09228]
105514686  LOW QUALITY PROTEIN: zinc finger protein 836-like [KO:K09228]
105514687  ZNF577; zinc finger protein 577 [KO:K09228]
105514688  ZNF613; zinc finger protein 613 isoform X1 [KO:K09228]
105514690  ZNF350; zinc finger protein 350 isoform X1 [KO:K09228]
105514697  ZNF175; zinc finger protein 175 [KO:K09228]
105514746  ZNF473; zinc finger protein 473 isoform X1 [KO:K09228]
105521515  ZNF670; zinc finger protein 670 isoform X1 [KO:K09228]
105521517  ZNF695; zinc finger protein 695 [KO:K09228]
105521518  ZNF669; zinc finger protein 669 [KO:K09228]
105521519  ZNF124; zinc finger protein 124 isoform X1 [KO:K09228]
105521522  zinc finger protein 695-like [KO:K09228]
105521645  ZNF275; zinc finger protein 275 [KO:K09228]
105521658  ZFP92; zinc finger protein 92 homolog [KO:K09228]
105525011  ZNF678; LOW QUALITY PROTEIN: zinc finger protein 678 [KO:K09228]
105500318  BST2; bone marrow stromal antigen 2 [KO:K06731]
105502648  IFNG; interferon gamma [KO:K04687]
105526167  IFNGR1; interferon gamma receptor 1 [KO:K05132]
105524763  IFNGR2; interferon gamma receptor 2 [KO:K05133]
105508462  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
105514226  DAXX; death domain-associated protein 6 [KO:K02308]
105518873  SP100; nuclear autoantigen Sp-100 [KO:K15413]
105505178  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
105513792  TAP1; antigen peptide transporter 1 isoform X1 [KO:K05653] [EC:7.4.2.14]
105513794  TAP2; antigen peptide transporter 2 isoform X1 [KO:K05654] [EC:7.4.2.14]
105514232  TAPBP; tapasin isoform X1 [KO:K08058]
105511093  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
105520787  CALR; calreticulin [KO:K08057]
105500736  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
105513804  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513823  mamu class I histocompatibility antigen, alpha chain F-like isoform X1 [KO:K06751]
105513934  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
105513935  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513936  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
105513982  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E-like [KO:K06751]
105513984  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [KO:K06751]
105513986  HLA class I histocompatibility antigen, B-67 alpha chain-like [KO:K06751]
105513995  LOW QUALITY PROTEIN: histocompatibility antigen-related [KO:K06751]
105511106  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
105501359  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
105501360  HLA class II histocompatibility antigen, DQ alpha 2 chain isoform X1 [KO:K06752]
105501361  HLA class II histocompatibility antigen, DRB1-4 beta chain-like [KO:K06752]
105502761  HLA class II histocompatibility antigen, DRB1-4 beta chain isoform X1 [KO:K06752]
105513785  mamu class II histocompatibility antigen, DR alpha chain isoform X1 [KO:K06752]
105513786  HLA class II histocompatibility antigen, DRB1-10 beta chain isoform X1 [KO:K06752]
105513788  HLA class II histocompatibility antigen, DRB1-9 beta chain isoform X1 [KO:K06752]
105513789  HLA class II histocompatibility antigen, DQ alpha 2 chain isoform X1 [KO:K06752]
105513790  HLA class II histocompatibility antigen, DQ beta 1 chain-like isoform X1 [KO:K06752]
105513791  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
105513797  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
105513798  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
105513800  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
105513801  HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
105513802  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
105514240  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105514272  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105514273  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105504233  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
105523405  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
105523708  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
105507333  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
105524169  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
105500411  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
105515019  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
105518411  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105519178  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
105521497  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105503993  TSC1; hamartin isoform X1 [KO:K07206]
105526466  TSC2; tuberin [KO:K07207]
105511346  RHEB; GTP-binding protein Rheb [KO:K07208]
105507357  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
105525209  EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
105514178  SRPK1; SRSF protein kinase 1 [KO:K15409] [EC:2.7.11.1]
105520112  SRSF1; serine/arginine-rich splicing factor 1 isoform X1 [KO:K12890]
105519014  SRSF2; serine/arginine-rich splicing factor 2 isoform X1 [KO:K12891]
105500904  serine/arginine-rich splicing factor 8-like [KO:K12891]
105500905  serine/arginine-rich splicing factor 8 [KO:K12891]
105514165  SRSF3; serine/arginine-rich splicing factor 3 isoform X1 [KO:K12892]
105502597  SRSF6; serine/arginine-rich splicing factor 6 [KO:K12893]
105517220  SRSF5; serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
105527575  serine/arginine-rich splicing factor 6 [KO:K12893]
105521317  SRSF4; serine/arginine-rich splicing factor 4 isoform X1 [KO:K12893]
105507454  SRSF7; serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
105516401  SRSF9; serine/arginine-rich splicing factor 9 [KO:K21123]
105512253  NXF1; nuclear RNA export factor 1 isoform X1 [KO:K14284]
105520588  NXF3; nuclear RNA export factor 3 isoform X1 [KO:K14284]
105520701  NXF5; LOW QUALITY PROTEIN: nuclear RNA export factor 5 [KO:K14284]
105500773  LOW QUALITY PROTEIN: nuclear RNA export factor 2-like [KO:K14284]
105505522  ALYREF; THO complex subunit 4 [KO:K12881]
105526354  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
105515921  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
105518659  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
105504584  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
105512314  FADD; FAS-associated death domain protein [KO:K02373]
105517408  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
105514348  BID; BH3-interacting domain death agonist [KO:K04726]
105514789  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
105514219  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
105512212  BAD; bcl2-associated agonist of cell death [KO:K02158]
105520028  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
105524720  BCL2L1; bcl-2-like protein 1 [KO:K04570]
105521896  cytochrome c-like [KO:K08738]
105509147  cytochrome c-like [KO:K08738]
105509351  cytochrome c [KO:K08738]
105516629  cytochrome c-like [KO:K08738]
105506411  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
105510236  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
105524344  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
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Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
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Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
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MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
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PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
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Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
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Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
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PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
PMID:15056211
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
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Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
PMID:12855695
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
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J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
PMID:24262390
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
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J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
PMID:26952111
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Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
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Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
PMID:21994567
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Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
PMID:15276609
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
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Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
PMID:29298887
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
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J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
PMID:19344302
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Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
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Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
PMID:23115300
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
  Journal
J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
PMID:17229694
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
Reference
PMID:12826401
  Authors
Wysocka J, Herr W
  Title
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
  Journal
Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
Reference
PMID:27367734
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
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Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
Reference
PMID:15163721
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
Reference
PMID:23864622
  Authors
Gu H, Zheng Y, Roizman B
  Title
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
  Journal
J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
Reference
PMID:21994592
  Authors
Tavalai N, Stamminger T
  Title
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
  Journal
Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
Reference
PMID:21146386
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:12960333
  Authors
Neumann J, Eis-Hubinger AM, Koch N
  Title
Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
  Journal
J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
Reference
PMID:25798530
  Authors
Liu X, Cohen JI
  Title
The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
  Journal
Virology 479-480:568-77 (2015)
DOI:10.1016/j.virol.2015.02.040
Reference
PMID:28468873
  Authors
Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
  Journal
J Virol 91:e00295-17 (2017)
DOI:10.1128/JVI.00295-17
Reference
PMID:18508584
  Authors
Sandri-Goldin RM
  Title
The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
  Journal
Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
Reference
PMID:15078920
  Authors
Sandri-Goldin RM
  Title
Viral regulation of mRNA export.
  Journal
J Virol 78:4389-96 (2004)
DOI:10.1128/JVI.78.9.4389-4396.2004
Reference
PMID:27154074
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
cang03040  Spliceosome
cang03050  Proteasome
cang04115  p53 signaling pathway
cang04151  PI3K-Akt signaling pathway
cang04210  Apoptosis
cang04610  Complement and coagulation cascades
cang04612  Antigen processing and presentation
cang04620  Toll-like receptor signaling pathway
cang04622  RIG-I-like receptor signaling pathway
cang04630  JAK-STAT signaling pathway
KO pathway
ko05168   
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