KEGG   PATHWAY: csai04621
Entry
csai04621                   Pathway                                
Name
NOD-like receptor signaling pathway - Cololabis saira (Pacific saury)
Description
Specific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains more than 20 members in mammals and plays a pivotal role in the recognition of intracellular ligands. NOD1 and NOD2, two prototypic NLRs, sense the cytosolic presence of the bacterial peptidoglycan fragments that escaped from endosomal compartments, driving the activation of NF-{kappa}B and MAPK, cytokine production and apoptosis. On the other hand, a different set of NLRs induces caspase-1 activation through the assembly of multiprotein complexes called inflammasomes. The activated of caspase-1 regulates maturation of the pro-inflammatory cytokines IL-1B, IL-18 and drives pyroptosis.
Class
Organismal Systems; Immune system
Pathway map
csai04621  NOD-like receptor signaling pathway
csai04621

Organism
Cololabis saira (Pacific saury) [GN:csai]
Gene
133424272  nucleotide-binding oligomerization domain-containing protein 1-like [KO:K08727]
133424393  nucleotide-binding oligomerization domain-containing protein 1-like [KO:K08727]
133453032  receptor-interacting serine/threonine-protein kinase 2-like [KO:K08846] [EC:2.7.11.1]
133456872  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
133463692  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
133419240  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
133450689  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
133418715  NF-kappa-B inhibitor alpha-like [KO:K04734]
133462483  nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b [KO:K04734]
133446759  nfkb1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
133419990  rela; LOW QUALITY PROTEIN: transcription factor p65 [KO:K04735]
133450972  interleukin-1 beta-like [KO:K04519]
133461206  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
133420553  interleukin-8-like [KO:K10030]
133451241  interleukin-8-like [KO:K10030]
133421499  nod2; nucleotide-binding oligomerization domain-containing protein 2 [KO:K10165]
133418642  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
133442583  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
133418574  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
133458448  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [KO:K12793]
133451560  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
133422106  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
133446927  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
133419376  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
133454946  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
133463188  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
133424507  mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
133424599  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
133448813  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
133457237  mapk14a; mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
133443998  mapk12a; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
133457392  mapk13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
133457477  zgc:171775; STKc_p38 domain-containing protein [KO:K04441] [EC:2.7.11.24]
133451783  transcription factor JunD-like [KO:K04448]
133452308  transcription factor JunD-like [KO:K04448]
133458200  jun; transcription factor AP-1 [KO:K04448]
133453062  transcription factor Jun-like [KO:K04448]
133442061  atg16l1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
133440335  atg5; autophagy protein 5 [KO:K08339]
133441045  atg12; ubiquitin-like protein ATG12 [KO:K08336]
133434362  zgc:92606; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
133420093  gabarapa; GABA(A) receptor-associated protein a [KO:K08341]
133443914  gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
133446126  map1lc3c; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
133447593  map1lc3cl; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
133449202  map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
133443856  map1lc3b; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
133453126  sugt1; protein SGT1 homolog isoform X1 [KO:K12795]
133448343  rbck1; ranBP-type and C3HC4-type zinc finger-containing protein 1 [KO:K10630] [EC:2.3.2.31]
133422933  shrprbck1r; ranBP-type and C3HC4-type zinc finger-containing protein 1 [KO:K10630] [EC:2.3.2.31]
133447221  xiap; E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
133420005  trip6; thyroid receptor-interacting protein 6 isoform X1 [KO:K12792]
133455092  erbin; erbin isoform X1 [KO:K12796]
133459634  birc2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
133455207  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
133450814  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
133447461  traf5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
133458825  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
133451200  card9; caspase recruitment domain-containing protein 9 [KO:K12794]
133463293  tnfaip3; tumor necrosis factor alpha-induced protein 3 isoform X1 [KO:K11859] [EC:3.4.19.12]
133462842  mavs; mitochondrial antiviral-signaling protein [KO:K12648]
133462914  traf3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
133423903  tbk1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
133448781  ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
133445975  tank; TRAF family member-associated NF-kappa-B activator isoform X1 [KO:K12650]
133418955  irf3; interferon regulatory factor 3 [KO:K05411]
133444698  irf7; interferon regulatory factor 7 [KO:K09447]
133419213  interferon a3-like [KO:K05414]
133419232  interferon a3-like [KO:K05414]
133419243  interferon a3-like [KO:K05414]
133419251  interferon a3-like [KO:K05414]
133441443  nlrx1; NLR family member X1 isoform X1 [KO:K12653]
133451541  antxr2a; ANTXR cell adhesion molecule 2a [KO:K20909]
133463834  antxr1d; anthrax toxin receptor 1 [KO:K20909]
133418990  antxr1c; anthrax toxin receptor 1 [KO:K20909]
133455269  anthrax toxin receptor 1-like [KO:K20909]
133455372  anthrax toxin receptor 2-like [KO:K20909]
133450348  anthrax toxin receptor 1-like isoform X1 [KO:K20909]
133438568  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133438586  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133440450  uncharacterized protein LOC133440450 [KO:K12799]
133440453  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133440648  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133440649  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133441137  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
133441804  caspase a-like isoform X1 [KO:K01370] [EC:3.4.22.36]
133441807  caspase a-like [KO:K01370] [EC:3.4.22.36]
133442377  caspase a-like [KO:K01370] [EC:3.4.22.36]
133452737  bcl2b; apoptosis regulator Bcl-2 [KO:K02161]
133449583  bcl-2-like protein 1 [KO:K04570]
133456602  bcl2l1; bcl-2-like protein 1 [KO:K04570]
133463675  ctsba; cathepsin B [KO:K01363] [EC:3.4.22.1]
133418479  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
133445486  pannexin-1-like [KO:K03443]
133442242  pannexin-1-like [KO:K03443]
133451515  p2rx7; P2X purinoceptor 7 [KO:K05220]
133446011  trpm2; transient receptor potential cation channel subfamily M member 2 isoform X1 [KO:K04977] [EC:3.6.1.13]
133464448  LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 7-like [KO:K04982] [EC:2.7.11.1]
133460245  casr; extracellular calcium-sensing receptor [KO:K04612]
133424446  G-protein coupled receptor family C group 6 member A-like [KO:K04622]
133418496  G-protein coupled receptor family C group 6 member A-like isoform X1 [KO:K04622]
133440839  G-protein coupled receptor family C group 6 member A-like isoform X1 [KO:K04622]
133464380  plcb1l; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
133418720  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like [KO:K05858] [EC:3.1.4.11]
133420813  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
133462872  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
133463587  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
133448733  itpr1a; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
133448914  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
133444381  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
133456934  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
133460033  vdac1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
133464017  vdac2; voltage-dependent anion-selective channel protein 2 [KO:K15040]
133419146  voltage-dependent anion-selective channel protein 2-like [KO:K15040]
133455117  zgc:56235; voltage-dependent anion-selective channel protein 2-like [KO:K15041]
133450691  vdac3; voltage-dependent anion-selective channel protein 3 isoform X1 [KO:K15041]
133464187  mcu; calcium uniporter protein, mitochondrial [KO:K20858]
133459826  dhx33; ATP-dependent RNA helicase DHX33 [KO:K17820] [EC:5.6.2.6]
133458469  mfn1b; mitofusin-1b [KO:K21356] [EC:3.6.5.-]
133452968  mitofusin-1-like isoform X1 [KO:K21356] [EC:3.6.5.-]
133457549  mfn2; mitofusin-2 [KO:K06030] [EC:3.6.5.-]
133457551  mitofusin-2-like [KO:K06030] [EC:3.6.5.-]
133452764  ripk1l; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
133444770  receptor-interacting serine/threonine-protein kinase 3-like [KO:K08847] [EC:2.7.11.1]
133420168  ripk3; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
133444309  receptor-interacting serine/threonine-protein kinase 3-like [KO:K08847] [EC:2.7.11.1]
133444311  receptor-interacting serine/threonine-protein kinase 3-like [KO:K08847] [EC:2.7.11.1]
133424409  dynamin-1-like protein isoform X1 [KO:K17065] [EC:3.6.5.5]
133450352  si:dkey-32e23.4; dynamin-1-like protein isoform X1 [KO:K17065] [EC:3.6.5.5]
133443799  dnm1l; dynamin-1-like protein isoform X1 [KO:K17065] [EC:3.6.5.5]
133423793  nampt1; nicotinamide phosphoribosyltransferase [KO:K03462] [EC:2.4.2.12]
133449546  nampt2; nicotinamide phosphoribosyltransferase 2 [KO:K03462] [EC:2.4.2.12]
133424888  LOW QUALITY PROTEIN: cytochrome b-245 heavy chain [KO:K21421] [EC:1.-.-.-]
133420912  cytochrome b-245 light chain [KO:K08009]
133460536  txnipa; thioredoxin interacting protein a [KO:K20910]
133440551  thioredoxin-interacting protein-like [KO:K20910]
133420756  txn; thioredoxin [KO:K03671]
133421685  txn2; thioredoxin, mitochondrial [KO:K03671]
133458671  nek7; LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek7 [KO:K20876] [EC:2.7.11.34]
133443655  brcc3; lys-63-specific deubiquitinase [KO:K11864] [EC:3.4.19.-]
133418440  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
133418505  hsp90aa1.2; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [KO:K04079]
133418511  hsp90aa1.1; heat shock protein HSP 90-alpha 1 [KO:K04079]
133456525  proline-serine-threonine phosphatase-interacting protein 1-like [KO:K12804]
133444237  pstpip1a; proline-serine-threonine phosphatase-interacting protein 1a isoform X1 [KO:K12804]
133445581  casp10; caspase-8 [KO:K04398] [EC:3.4.22.61]
133453127  caspase-8-like [KO:K04398] [EC:3.4.22.61]
133453128  caspase-8-like [KO:K04398] [EC:3.4.22.61]
133453129  caspase-8-like [KO:K04398] [EC:3.4.22.61]
133419352  fadd; protein FADD [KO:K02373]
133448765  prkcda; protein kinase C, delta a [KO:K06068] [EC:2.7.11.13]
133458541  tp53bp1; TP53-binding protein 1 isoform X1 [KO:K20915]
133448371  rho-related GTP-binding protein RhoA-D-like isoform X1 [KO:K04513]
133448529  rho-related GTP-binding protein RhoA-B [KO:K04513]
133456909  rho-related GTP-binding protein RhoA-C [KO:K04513]
133457136  transforming protein RhoA-like [KO:K04513]
133457154  rho-related GTP-binding protein RhoA-D isoform X1 [KO:K04513]
133457430  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
133421461  pkn1b; serine/threonine-protein kinase N1b isoform X1 [KO:K06071] [EC:2.7.11.13]
133450639  pkn1a; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
133452889  pkn2a; serine/threonine-protein kinase N2 isoform X1 [KO:K23691] [EC:2.7.11.13]
133459932  14-3-3 protein epsilon isoform X1 [KO:K06630]
133441396  14-3-3 protein epsilon-like isoform X1 [KO:K06630]
133458618  jak1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
133421460  tyk2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
133425311  stat1a; signal transducer and activator of transcription 1a isoform X1 [KO:K11220]
133448749  stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
133423686  irf9; interferon regulatory factor 9 [KO:K04693]
133451940  ticam1; TIR domain-containing adapter molecule 1 [KO:K05842]
133423093  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
133443810  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
133447668  sting1; stimulator of interferon genes protein [KO:K12654]
Compound
C00002  ATP
C00076  Calcium cation
C00155  L-Homocysteine
C00238  Potassium cation
C00533  Nitric oxide
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:23124073
  Authors
Vandenabeele P, Bertrand MJ
  Title
The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling.
  Journal
Nat Rev Immunol 12:833-44 (2012)
DOI:10.1038/nri3325
Reference
PMID:16493424
  Authors
Strober W, Murray PJ, Kitani A, Watanabe T
  Title
Signalling pathways and molecular interactions of NOD1 and NOD2.
  Journal
Nat Rev Immunol 6:9-20 (2006)
DOI:10.1038/nri1747
Reference
PMID:24718315
  Authors
Estornes Y, Bertrand MJ
  Title
IAPs, regulators of innate immunity and inflammation.
  Journal
Semin Cell Dev Biol 39:106-14 (2015)
DOI:10.1016/j.semcdb.2014.03.035
Reference
PMID:24707857
  Authors
Jakopin Z
  Title
Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway.
  Journal
J Med Chem 57:6897-918 (2014)
DOI:10.1021/jm401841p
Reference
PMID:25526305
  Authors
Caruso R, Warner N, Inohara N, Nunez G
  Title
NOD1 and NOD2: signaling, host defense, and inflammatory disease.
  Journal
Immunity 41:898-908 (2014)
DOI:10.1016/j.immuni.2014.12.010
Reference
PMID:19767725
  Authors
Murray PJ
  Title
Beyond peptidoglycan for Nod2.
  Journal
Nat Immunol 10:1053-4 (2009)
DOI:10.1038/ni1009-1053
Reference
PMID:20643110
  Authors
Lecat A, Piette J, Legrand-Poels S
  Title
The protein Nod2: an innate receptor more complex than previously assumed.
  Journal
Biochem Pharmacol 80:2021-31 (2010)
DOI:10.1016/j.bcp.2010.07.016
Reference
PMID:26655628
  Authors
Man SM, Kanneganti TD
  Title
Converging roles of caspases in inflammasome activation, cell death and innate immunity.
  Journal
Nat Rev Immunol 16:7-21 (2016)
DOI:10.1038/nri.2015.7
Reference
PMID:27291964
  Authors
Broz P, Dixit VM
  Title
Inflammasomes: mechanism of assembly, regulation and signalling.
  Journal
Nat Rev Immunol 16:407-20 (2016)
DOI:10.1038/nri.2016.58
Reference
PMID:25879280
  Authors
Man SM, Kanneganti TD
  Title
Regulation of inflammasome activation.
  Journal
Immunol Rev 265:6-21 (2015)
DOI:10.1111/imr.12296
Reference
PMID:26549800
  Authors
Jo EK, Kim JK, Shin DM, Sasakawa C
  Title
Molecular mechanisms regulating NLRP3 inflammasome activation.
  Journal
Cell Mol Immunol 13:148-59 (2016)
DOI:10.1038/cmi.2015.95
Reference
PMID:23846113
  Authors
Broz P, Monack DM
  Title
Newly described pattern recognition receptors team up against intracellular pathogens.
  Journal
Nat Rev Immunol 13:551-65 (2013)
DOI:10.1038/nri3479
Reference
PMID:22430786
  Authors
Rathinam VA, Vanaja SK, Fitzgerald KA
  Title
Regulation of inflammasome signaling.
  Journal
Nat Immunol 13:333-42 (2012)
DOI:10.1038/ni.2237
Reference
PMID:24840700
  Authors
Sutterwala FS, Haasken S, Cassel SL
  Title
Mechanism of NLRP3 inflammasome activation.
  Journal
Ann N Y Acad Sci 1319:82-95 (2014)
DOI:10.1111/nyas.12458
Reference
PMID:23702978
  Authors
Latz E, Xiao TS, Stutz A
  Title
Activation and regulation of the inflammasomes.
  Journal
Nat Rev Immunol 13:397-411 (2013)
DOI:10.1038/nri3452
Reference
PMID:25145756
  Authors
Blander JM
  Title
A long-awaited merger of the pathways mediating host defence and programmed cell death.
  Journal
Nat Rev Immunol 14:601-18 (2014)
DOI:10.1038/nri3720
Reference
PMID:23215645
  Authors
von Moltke J, Ayres JS, Kofoed EM, Chavarria-Smith J, Vance RE
  Title
Recognition of bacteria by inflammasomes.
  Journal
Annu Rev Immunol 31:73-106 (2013)
DOI:10.1146/annurev-immunol-032712-095944
Reference
PMID:25330206
  Authors
Abais JM, Xia M, Zhang Y, Boini KM, Li PL
  Title
Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?
  Journal
Antioxid Redox Signal 22:1111-29 (2015)
DOI:10.1089/ars.2014.5994
Reference
PMID:25879288
  Authors
Storek KM, Monack DM
  Title
Bacterial recognition pathways that lead to inflammasome activation.
  Journal
Immunol Rev 265:112-29 (2015)
DOI:10.1111/imr.12289
Reference
PMID:27012466
  Authors
Hu H, Sun SC
  Title
Ubiquitin signaling in immune responses.
  Journal
Cell Res 26:457-83 (2016)
DOI:10.1038/cr.2016.40
Reference
PMID:26121197
  Authors
Guo H, Callaway JB, Ting JP
  Title
Inflammasomes: mechanism of action, role in disease, and therapeutics.
  Journal
Nat Med 21:677-87 (2015)
DOI:10.1038/nm.3893
Reference
PMID:26482951
  Authors
Man SM, Kanneganti TD
  Title
Gasdermin D: the long-awaited executioner of pyroptosis.
  Journal
Cell Res 25:1183-4 (2015)
DOI:10.1038/cr.2015.124
Reference
PMID:22819539
  Authors
Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA
  Title
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
  Journal
Cell 150:606-19 (2012)
DOI:10.1016/j.cell.2012.07.007
Reference
PMID:21575908
  Authors
Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B
  Title
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.
  Journal
Cell Host Microbe 9:363-75 (2011)
DOI:10.1016/j.chom.2011.04.008
Reference
PMID:29148036
  Authors
Heilig R, Broz P
  Title
Function and mechanism of the pyrin inflammasome.
  Journal
Eur J Immunol 48:230-238 (2018)
DOI:10.1002/eji.201746947
Reference
PMID:25816776
  Authors
Chakrabarti A, Banerjee S, Franchi L, Loo YM, Gale M Jr, Nunez G, Silverman RH
  Title
RNase L activates the NLRP3 inflammasome during viral infections.
  Journal
Cell Host Microbe 17:466-77 (2015)
DOI:10.1016/j.chom.2015.02.010
Related
pathway
csai04010  MAPK signaling pathway
csai04140  Autophagy - animal
csai04620  Toll-like receptor signaling pathway
KO pathway
ko04621   
LinkDB

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