Network variation - Cytoskeleton in neurons
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Network variation - Cytoskeleton in neurons
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| ENTRY | nt06541 |
| Name | Cytoskeleton in neurons |
| Category | Pathway view; Cellular process |
| Disease | H00266 Hereditary spastic paraplegia H00058 Amyotrophic lateral sclerosis H00268 Lissencephaly H00264 Charcot-Marie-Tooth disease H00768 Autosomal recessive intellectual developmental disorder H00773 Autosomal dominant intellectual developmental disorder H01881 Complex cortical dysplasia with other brain malformations H02022 Griscelli syndrome |
| Display | drug-target relation disease type |
| Disease name | Disease category | ||
| HH16 | H00255 | Hypogonadotropic hypogonadism | Endocrine and metabolic disease |
| MRMV4 | H01287 | Congenital mirror movements | Nervous system disease |
| CFNS | H00458 | Syndromic craniosynostoses | Congenital malformation |
| DWOPNED | H02688 | Dworschak-Punetha neurodevelopmental syndrome | Congenital malformation |
| FXS/POF1/FXTAS | H00465 | Fragile X syndrome | Chromosomal abnormality |
| H00627 | Premature ovarian failure | Reproductive system disease | |
| H01731 | Fragile X tremor/ataxia syndrome | Chromosomal abnormality | |
| MRMV1/HGPPS2 | H01287 | Congenital mirror movements | Nervous system disease |
| H02450 | Horizontal gaze palsy with progressive scoliosis | Nervous system disease | |
| PVNH9/DFNA83 | H00270 | Periventricular nodular heterotopia | Congenital malformation |
| H00604 | Deafness, autosomal dominant | Nervous system disease | |
| LISX1 | H00268 | Lissencephaly | Congenital malformation |
| ALSPDC/PSNP1 | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| H00077 | Progressive supranuclear palsy | Neurodegenerative disease | |
| FAP1 | H01025 | Familial adenomatous polyposis | Neoplasm |
| MRT74/CDCBM10 | H00768 | Autosomal recessive intellectual developmental disorder | Mental and behavioural disorder |
| H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation | |
| LIS9 | H00268 | Lissencephaly | Congenital malformation |
| HSAN6/EBS3 | H00265 | Hereditary sensory and autonomic neuropathy | Nervous system disease |
| H00584 | Epidermolysis bullosa simplex | Congenital malformation | |
| MRD44 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRD63 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MCPH17 | H00269 | Primary microcephaly | Congenital malformation |
| SMALED2 | H00455 | Spinal muscular atrophy | Neurodegenerative disease |
| NEDBA | H02862 | Neurodevelopmental disorder with or without variable brain abnormalities | Congenital malformation |
| CMT2O/SMALED1/CDCBM13 | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| H00455 | Spinal muscular atrophy | Neurodegenerative disease | |
| H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation | |
| SRTD3 | H02157 | Short-rib thoracic dysplasia | Congenital malformation |
| NEDMIBA | H02857 | Neurodevelopmental disorder with microcephaly and structural brain anomalies | Congenital malformation |
| ALS1/HMND14/PS | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| H00856 | Distal hereditary motor neuropathies | Nervous system disease | |
| H00879 | Perry syndrome | Neurodegenerative disease | |
| LIS4/MHAC | H00268 | Lissencephaly | Congenital malformation |
| H01870 | Microhydranencephaly | Congenital malformation | |
| LIS1/MDS | H00268 | Lissencephaly | Congenital malformation |
| CDCBM3 | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| DEE68 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| SPG10/NEIMY | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| H02819 | Neonatal intractable myoclonus | Nervous system disease | |
| ALS25 | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| CDCBM2 | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| SPOAN | H02114 | Spastic paraplegia, optic atrophy, and neuropathy | Nervous system disease |
| RP89 | H00527 | Retinitis pigmentosa | Nervous system disease |
| HSAN2C/SPG30/MRD9 | H00265 | Hereditary sensory and autonomic neuropathy | Nervous system disease |
| H00266 | Hereditary spastic paraplegia | Nervous system disease | |
| H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder | |
| CMT2A1 | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| SPAX2 | H01351 | Spastic ataxia | Neurodegenerative disease |
| CFEOM1/3B | H00838 | Congenital fibrosis of the extraocular muscles | Nervous system disease |
| CDAIIIA | H00917 | Congenital dyserythropoietic anemia | Hematologic disease |
| BRDCS2 | H02663 | Braddock-Carey syndrome | Congenital malformation |
| SPG4 | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| LIS6 | H00268 | Lissencephaly | Congenital malformation |
| LIS3 | H00268 | Lissencephaly | Congenital malformation |
| KTCN | H00789 | Keratoconus | Nervous system disease |
| ALS22 | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| MACTHC2 | H01740 | Macrothrombocytopenia | Hematologic disease |
| CDCBM6/CSCSC1 | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| H01579 | Congenital symmetric circumferential skin creases | Congenital malformation | |
| MACTHC1 | H01740 | Macrothrombocytopenia | Hematologic disease |
| CDCBM5 | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| CDCBM7 | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| CDCBM1/CFEOM3A | H01881 | Complex cortical dysplasia with other brain malformations | Congenital malformation |
| H00838 | Congenital fibrosis of the extraocular muscles | Nervous system disease | |
| HLD6/DYT4 | H00679 | Hypomyelinating leukodystrophy | Inherited metabolic disorder |
| H00831 | Primary dystonia | Nervous system disease | |
| LCAEOD | H00837 | Leber congenital amaurosis | Nervous system disease |
| FPVEPD | H02594 | Congenital facial palsy with ptosis and velopharyngeal dysfunction | Nervous system disease |
| OOMD2 | H01897 | Oocyte/zygote/embryo maturation arrest | Reproductive system disease |
| BNS | H02716 | Becker nevus syndrome | Congenital malformation |
| BRWS1/DDS1 | H02023 | Baraitser-Winter syndrome | Congenital malformation |
| H01255 | Juvenile-onset dystonia | Congenital malformation | |
| DFNA20/26/BRWS2 | H00604 | Deafness, autosomal dominant | Nervous system disease |
| H02023 | Baraitser-Winter syndrome | Congenital malformation | |
| ALS18 | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| EHT | H01633 | High blood pressure | Cardiovascular disease |
| CPSQ3 | H01097 | Spastic quadriplegic cerebral palsy | Nervous system disease |
| SPG91/DEE5/HMND11 | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| H00606 | Early infantile epileptic encephalopathy | Nervous system disease | |
| H00856 | Distal hereditary motor neuropathies | Nervous system disease | |
| DDISBA | H02685 | Developmental delay with neuropsychiatric disorders | Congenital malformation |
| CMND | H01810 | Congenital myopathy | Nervous system disease |
| MATINS/DFNA17 | H00233 | MYH9-related disease | Cardiovascular disease |
| H00604 | Deafness, autosomal dominant | Nervous system disease | |
| PFIC10/DIAR2/MVID1 | H00624 | Progressive familial intrahepatic cholestasis | Inherited metabolic disorder |
| H01174 | Congenital diarrhea | Digestive system disease | |
| MRT63 | H00768 | Autosomal recessive intellectual developmental disorder | Mental and behavioural disorder |
| MRD53 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRD54 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| NDAGSCW | H02863 | Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | Congenital malformation |
| MRD67 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRT76 | H00768 | Autosomal recessive intellectual developmental disorder | Mental and behavioural disorder |
| GS1 | H02022 | Griscelli syndrome | Primary immunodeficiency |
| GS3 | H02022 | Griscelli syndrome | Primary immunodeficiency |
| GS2 | H02022 | Griscelli syndrome | Primary immunodeficiency |
| DFNA22/DFNB37 | H00604 | Deafness, autosomal dominant | Nervous system disease |
| H00605 | Deafness, autosomal recessive | Nervous system disease | |
| OPDM2 | H02513 | Oculopharyngodistal myopathy | Musculoskeletal disease |
| CMT1F/2E/DIG | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| ALS1 | H00058 | Amyotrophic lateral sclerosis (ALS) | Neurodegenerative disease |
| RP7/VMD3/CACD2/MDPT1 | H00527 | Retinitis pigmentosa | Nervous system disease |
| H00814 | Vitelliform macular dystrophy | Nervous system disease | |
| H01768 | Central areolar choroidal dystrophy | Nervous system disease | |
| H01890 | Pattern dystrophies of the retinal pigment epithelium | Nervous system disease | |
| CMT2CC | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| CMT2R | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| NEDAUS | H02864 | Neurodevelopmental disorder with or without autism or seizures | Congenital malformation |
| GAN1 | H01259 | Giant axonal neuropathy | Neurodegenerative disease |
| PCH3 | H00897 | Pontocerebellar hypoplasia | Congenital malformation |