KEGG   PATHWAY: ggo04060
Entry
ggo04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Gorilla gorilla gorilla (western lowland gorilla)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
ggo04060  Cytokine-cytokine receptor interaction
ggo04060

Organism
Gorilla gorilla gorilla (western lowland gorilla) [GN:ggo]
Gene
101136979  CCL1; C-C motif chemokine 1 [KO:K05514]
101127255  CCL25; C-C motif chemokine 25 [KO:K13072]
101131144  CCL19; C-C motif chemokine 19 [KO:K05512]
101131506  CCL21; C-C motif chemokine 21 [KO:K16062]
101139671  uncharacterized protein LOC101139671 [KO:K05408]
101153934  CCL3; C-C motif chemokine 3 [KO:K05408]
101140367  uncharacterized protein LOC101140367 isoform X1 [KO:K12964]
101123729  C-C motif chemokine 4 [KO:K12964]
101137209  CCL17; C-C motif chemokine 17 isoform X1 [KO:K21083]
101136833  CCL22; C-C motif chemokine 22 [KO:K21095]
101125807  CCL5; C-C motif chemokine 5 isoform X1 [KO:K12499]
101136244  CCL8; C-C motif chemokine 8 [KO:K16596]
101151907  CCL14; C-C motif chemokine 14 [KO:K21092]
101152257  CCL16; C-C motif chemokine 16 [KO:K21093]
101151296  CCL15; C-C motif chemokine 15 [KO:K05511]
101152982  CCL23; C-C motif chemokine 23 [KO:K05511]
101136620  CCL13; C-C motif chemokine 13 [KO:K16595]
101135169  CCL7; C-C motif chemokine 7 [KO:K05509]
101134802  CCL2; C-C motif chemokine 2 [KO:K14624]
101135883  CCL11; eotaxin [KO:K16597]
101136648  CCL24; C-C motif chemokine 24 [KO:K21097]
101130287  CCL27; C-C motif chemokine 27 [KO:K16598]
101132959  uncharacterized protein LOC101132959 [KO:K16598]
101139674  CCL28; C-C motif chemokine 28 isoform X1 [KO:K05513]
101153586  CCL18; C-C motif chemokine 18 [KO:K21094]
101135965  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
101134092  C-X-C motif chemokine 2 [KO:K05505]
101131798  CXCL1; growth-regulated alpha protein [KO:K05505]
101133388  CXCL3; C-X-C motif chemokine 3 [KO:K05505]
101133017  CXCL5; C-X-C motif chemokine 5 [KO:K05506]
101131085  CXCL6; C-X-C motif chemokine 6 [KO:K05506]
101130732  CXCL8; interleukin-8 [KO:K10030]
101132641  PPBP; platelet basic protein [KO:K10029]
101131442  PF4V1; platelet factor 4 variant [KO:K05407]
101132278  PF4; platelet factor 4 [KO:K05407]
101146258  CXCL9; C-X-C motif chemokine 9 [KO:K05416]
101147442  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
101148155  CXCL11; C-X-C motif chemokine 11 isoform X2 [KO:K12672]
101125793  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
101124266  CXCL12; stromal cell-derived factor 1 isoform X2 [KO:K10031]
101132654  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
101133874  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
101146171  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
101143893  lymphotactin [KO:K05507]
115931927  lymphotactin [KO:K05507]
101137562  CX3CL1; fractalkine [KO:K05508]
101132394  IL2; interleukin-2 [KO:K05429]
101140015  IL4; interleukin-4 isoform X1 [KO:K05430]
101138372  IL7; interleukin-7 isoform X2 [KO:K05431]
101135761  IL9; interleukin-9 [KO:K05432]
101143213  IL15; interleukin-15 isoform X1 [KO:K05433]
101133146  IL21; interleukin-21 [KO:K05434]
101129775  TSLP; thymic stromal lymphopoietin [KO:K05436]
101132913  IL3; interleukin-3 [KO:K04736]
101138467  IL5; interleukin-5 [KO:K05428]
101133274  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
101139192  IL13; interleukin-13 isoform X1 [KO:K05435]
101141654  EPO; erythropoietin [KO:K05437]
101124194  GH1; somatotropin isoform X2 [KO:K05438]
101125803  chorionic somatomammotropin hormone 1 isoform X2 [KO:K05438]
101126399  GH2; growth hormone variant isoform X3 [KO:K05438]
101126984  chorionic somatomammotropin hormone 2 isoform X2 [KO:K05438]
115934631  chorionic somatomammotropin hormone 1-like [KO:K05438]
115934632  chorionic somatomammotropin hormone 1 isoform X1 [KO:K05438]
101141749  PRL; prolactin [KO:K05439]
101153569  THPO; thrombopoietin isoform X1 [KO:K06854]
101145303  CSF3; granulocyte colony-stimulating factor isoform X1 [KO:K05423]
101130896  LEP; leptin isoform X1 [KO:K05424]
101151687  IL6; interleukin-6 isoform X1 [KO:K05405]
115933451  IL11; interleukin-11 isoform X1 [KO:K05417]
101150677  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
101141274  IL12B; interleukin-12 subunit beta [KO:K05425]
101146347  IL23A; interleukin-23 subunit alpha [KO:K05426]
101133023  IL27; LOW QUALITY PROTEIN: interleukin-27 subunit alpha [KO:K22629]
101126952  IL31; interleukin-31 [KO:K22631]
101133219  CLCF1; cardiotrophin-like cytokine factor 1 isoform X1 [KO:K05421]
101152328  CNTF; ciliary neurotrophic factor [KO:K05420]
101126036  CTF1; cardiotrophin-1 isoform X1 [KO:K05422]
101126398  cardiotrophin-2 [KO:K24382]
101137862  LIF; leukemia inhibitory factor [KO:K05419]
101138490  OSM; oncostatin-M isoform X1 [KO:K05418]
101130439  IL10; interleukin-10 [KO:K05443]
101130815  IL19; interleukin-19 isoform X2 [KO:K05444]
101131402  IL20; interleukin-20 isoform X1 [KO:K22667]
101132114  IL24; LOW QUALITY PROTEIN: interleukin-24 [KO:K22668]
101152715  IL22; interleukin-22 [KO:K05445]
101152103  IL26; interleukin-26 [KO:K05446]
101153729  interferon lambda-3 [KO:K22669]
109024085  interferon lambda-3-like [KO:K22669]
115931638  interferon lambda-3 [KO:K22669]
101154093  interferon lambda-1 [KO:K05447]
101139336  interferon alpha-16 [KO:K05414]
101140412  interferon alpha-5 [KO:K05414]
101142673  interferon alpha-1/13 [KO:K05414]
101142301  IFNA8; interferon alpha-8 [KO:K05414]
101141176  IFNA6; interferon alpha-6 [KO:K05414]
101141543  interferon alpha-1/13 [KO:K05414]
101141916  IFNA2; interferon alpha-2 [KO:K05414]
101137870  IFNA21; interferon alpha-21 [KO:K05414]
101138981  interferon alpha-17 [KO:K05414]
101139713  interferon alpha-14 [KO:K05414]
115935827  interferon alpha-4 [KO:K05414]
115935828  interferon alpha-7 [KO:K05414]
115935829  interferon alpha-4-like [KO:K05414]
115935831  interferon alpha-16-like [KO:K05414]
115935832  interferon alpha-7 [KO:K05414]
115935833  interferon alpha-7 [KO:K05414]
115935834  interferon alpha-7 [KO:K05414]
101137136  IFNB1; interferon beta [KO:K05415]
101137485  interferon omega-1 [KO:K05440]
101124868  IFNK; interferon kappa [KO:K05441]
101143032  IFNE; interferon epsilon [KO:K05442]
101151755  IFNG; interferon gamma [KO:K04687]
101129849  IL1A; interleukin-1 alpha [KO:K04383]
101130571  IL1B; interleukin-1 beta [KO:K04519]
101135959  IL1RN; interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
101135252  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
101134282  IL36A; interleukin-36 alpha [KO:K05484]
101134640  IL36B; interleukin-36 beta isoform X2 [KO:K05486]
101133601  IL36G; interleukin-36 gamma isoform X1 [KO:K05487]
101135602  IL1F10; interleukin-1 family member 10 isoform X2 [KO:K05488]
101130935  IL37; interleukin-37 isoform X1 [KO:K05485]
101138403  IL18; interleukin-18 isoform X3 [KO:K05482]
101125720  IL33; interleukin-33 isoform X1 [KO:K12967]
101142509  IL17A; interleukin-17A [KO:K05489]
101143595  IL17F; interleukin-17F [KO:K05494]
101147825  IL17B; interleukin-17B [KO:K05490]
101141867  IL17C; interleukin-17C isoform X2 [KO:K05491]
101125278  IL17D; interleukin-17D [KO:K05492]
101137917  IL25; interleukin-25 isoform X2 [KO:K05493]
101132163  IL16; pro-interleukin-16 isoform X1 [KO:K22628]
101129143  IL32; interleukin-32 isoform X2 [KO:K22632]
101131872  CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453]
101150218  lymphotoxin-alpha [KO:K05468]
101135183  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
101137781  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
101141431  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
101151832  EDA; ectodysplasin-A isoform X3 [KO:K05480]
101149785  NGF; beta-nerve growth factor isoform X2 [KO:K02582]
101131644  TNFSF11; tumor necrosis factor ligand superfamily member 11 isoform X1 [KO:K05473]
101127495  TNFSF12; tumor necrosis factor ligand superfamily member 12 isoform X2 [KO:K05474]
109025563  TNFSF8; tumor necrosis factor ligand superfamily member 8 isoform X1 [KO:K05471]
101152672  CD40LG; CD40 ligand isoform X1 [KO:K03161]
101137954  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
101139622  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
101138527  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
109023039  TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X1 [KO:K05475]
101147199  TNFSF13B; tumor necrosis factor ligand superfamily member 13B isoform X1 [KO:K05476]
101124474  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
101125504  TGFB2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
101133741  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
101127987  GDF15; growth/differentiation factor 15 [KO:K05504]
101150379  GDF2; growth/differentiation factor 2 [KO:K05503]
101129956  BMP10; bone morphogenetic protein 10 [KO:K22670]
101145386  INHA; inhibin alpha chain [KO:K05500]
101137550  BMP3; bone morphogenetic protein 3 [KO:K05496]
101150748  GDF10; growth/differentiation factor 10 [KO:K22674]
101131997  GDF11; growth/differentiation factor 11 [KO:K22679]
101135255  MSTN; growth/differentiation factor 8 [KO:K05497]
101152285  INHBA; inhibin beta A chain [KO:K04667]
101133226  INHBB; inhibin beta B chain [KO:K22687]
101152764  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
101151622  GDF3; growth/differentiation factor 3 [KO:K22672]
101141191  NODAL; nodal homolog isoform X1 [KO:K04666]
101143720  growth/differentiation factor 9 [KO:K22673]
101138285  INHBC; inhibin beta C chain [KO:K22688]
101138658  INHBE; inhibin beta E chain [KO:K22689]
101137456  AMH; muellerian-inhibiting factor [KO:K04665]
101149410  BMP2; bone morphogenetic protein 2 [KO:K21283]
101126138  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
101127151  GDF6; growth/differentiation factor 6 [KO:K20012]
101129236  GDF7; growth/differentiation factor 7 [KO:K20013]
101138976  BMP15; bone morphogenetic protein 15 [KO:K05498]
101136011  BMP5; bone morphogenetic protein 5 isoform X1 [KO:K04663]
101152759  BMP6; bone morphogenetic protein 6 [KO:K16620]
101142520  BMP7; bone morphogenetic protein 7 [KO:K16621]
101149312  BMP8A; bone morphogenetic protein 8A [KO:K16622]
115933734  BMP8B; bone morphogenetic protein 8B [KO:K16622]
101127090  CCR8; C-C chemokine receptor type 8 isoform X1 [KO:K04183]
101145517  CCR9; C-C chemokine receptor type 9 isoform X1 [KO:K04184]
101150674  ACKR4; atypical chemokine receptor 4 [KO:K04186]
101152751  CCR7; C-C chemokine receptor type 7 [KO:K04182]
101124679  CCR4; C-C chemokine receptor type 4 [KO:K04179]
101153198  CCR5; C-C chemokine receptor type 5 [KO:K04180]
101151267  CCR3; C-C chemokine receptor type 3 isoform X3 [KO:K04178]
101152844  CCR2; C-C chemokine receptor type 2 [KO:K04177]
101150910  CCR1; C-C chemokine receptor type 1 [KO:K04176]
101125806  CCR10; C-C chemokine receptor type 10 [KO:K04185]
101137728  CCR6; C-C chemokine receptor type 6 [KO:K04181]
101152473  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
101151143  C-X-C chemokine receptor type 2 [KO:K05050]
101141174  CXCR3; C-X-C chemokine receptor type 3 isoform X2 [KO:K04188]
101128041  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
101137662  CXCR4; C-X-C chemokine receptor type 4 isoform X1 [KO:K04189]
101126486  ACKR3; atypical chemokine receptor 3 [KO:K04304]
101147909  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
101148758  XCR1; chemokine XC receptor 1 [KO:K04193]
101125281  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
101126210  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
101139583  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
101124934  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
101140372  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
101131507  interleukin-9 receptor-like [KO:K05073]
101126682  LOW QUALITY PROTEIN: interleukin-9 receptor-like [KO:K05073]
109027695  IL9R; interleukin-9 receptor isoform X1 [KO:K05073]
101125849  IL15RA; interleukin-15 receptor subunit alpha isoform X2 [KO:K05074]
101129403  IL21R; interleukin-21 receptor [KO:K05075]
101148206  CRLF2; cytokine receptor-like factor 2 isoform X1 [KO:K05078]
101136283  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
101146234  IL5RA; interleukin-5 receptor subunit alpha isoform X2 [KO:K05067]
101133803  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
101153265  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
101147948  EPOR; erythropoietin receptor [KO:K05079]
101147704  GHR; growth hormone receptor [KO:K05080]
101147940  PRLR; prolactin receptor [KO:K05081]
101151477  MPL; thrombopoietin receptor isoform X1 [KO:K05082]
101128750  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
101141324  LEPR; leptin receptor isoform X1 [KO:K05062]
101130311  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
101153224  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
101128866  IL11RA; interleukin-11 receptor subunit alpha [KO:K05056]
101134933  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
101144503  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
101143774  IL23R; interleukin-23 receptor [KO:K05065]
101130755  IL27RA; interleukin-27 receptor subunit alpha isoform X1 [KO:K19598]
101152875  IL31RA; interleukin-31 receptor subunit alpha isoform X1 [KO:K22630]
101125843  CNTFR; ciliary neurotrophic factor receptor subunit alpha isoform X2 [KO:K05059]
101128097  LIFR; leukemia inhibitory factor receptor [KO:K05058]
101129883  OSMR; oncostatin-M-specific receptor subunit beta isoform X2 [KO:K05057]
101153778  IL10RA; interleukin-10 receptor subunit alpha isoform X1 [KO:K05134]
101138228  IL10RB; interleukin-10 receptor subunit beta isoform X2 [KO:K05135]
101145811  IL20RA; interleukin-20 receptor subunit alpha isoform X1 [KO:K05136]
101140860  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
101129829  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
101130175  IFNLR1; interferon lambda receptor 1 isoform X1 [KO:K05140]
101141158  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
101140784  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
101150227  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
101144355  IFNGR2; interferon gamma receptor 2 [KO:K05133]
101133600  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
101126854  IL1RAP; interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
101132361  IL1R2; interleukin-1 receptor type 2 isoform X2 [KO:K04387]
101132992  IL1RL2; interleukin-1 receptor-like 2 isoform X1 [KO:K05172]
101138655  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
101139018  IL18RAP; interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
101134638  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
101137858  IL17RA; interleukin-17 receptor A isoform X1 [KO:K05164]
101136946  IL17RC; interleukin-17 receptor C isoform X18 [KO:K05166]
101142225  IL17RB; interleukin-17 receptor B [KO:K05165]
101139884  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
101130322  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
101151662  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
101149216  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
101136411  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B [KO:K05141]
101149920  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
101133688  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
101152441  FAS; tumor necrosis factor receptor superfamily member 6 isoform X3 [KO:K04390]
101127297  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X1 [KO:K05160]
101146659  TNFRSF10A; tumor necrosis factor receptor superfamily member 10A [KO:K04722]
101141415  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B isoform X1 [KO:K04722]
101141774  TNFRSF10C; tumor necrosis factor receptor superfamily member 10C [KO:K22701]
101143132  tumor necrosis factor receptor superfamily member 10D [KO:K22702]
115935615  tumor necrosis factor receptor superfamily member 10D-like [KO:K22702]
101126420  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
101138164  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X2 [KO:K05162]
101140930  EDA2R; tumor necrosis factor receptor superfamily member 27 isoform X3 [KO:K05163]
101139048  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
109025349  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
101133276  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A isoform X1 [KO:K05147]
101128219  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
101150894  CD27; CD27 antigen [KO:K05144]
101136038  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X1 [KO:K05145]
101126651  CD40; tumor necrosis factor receptor superfamily member 5 isoform X2 [KO:K03160]
101133085  TNFRSF9; tumor necrosis factor receptor superfamily member 9 [KO:K05146]
101142242  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
101135407  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
101141773  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C [KO:K05151]
101136805  TNFRSF19; tumor necrosis factor receptor superfamily member 19 isoform X2 [KO:K05155]
101135482  RELT; tumor necrosis factor receptor superfamily member 19L [KO:K05156]
101137355  RELL2; RELT-like protein 2 [KO:K26541]
101152001  RELL1; RELT-like protein 1 [KO:K26541]
101128510  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
101146131  TGFBR2; TGF-beta receptor type-2 isoform X2 [KO:K04388] [EC:2.7.11.30]
101147417  ACVRL1; serine/threonine-protein kinase receptor R3 [KO:K13594] [EC:2.7.11.30]
101126947  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
101152104  BMPR2; bone morphogenetic protein receptor type-2 isoform X1 [KO:K04671] [EC:2.7.11.30]
101153315  ACVR2B; activin receptor type-2B [KO:K13596] [EC:2.7.11.30]
101147783  ACVR1B; activin receptor type-1B isoform X2 [KO:K13567] [EC:2.7.11.30]
101153902  ACVR1C; activin receptor type-1C isoform X2 [KO:K13568] [EC:2.7.11.30]
101124161  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
101149682  AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 [KO:K04672] [EC:2.7.11.30]
101135109  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
101127602  BMPR1B; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
PMID:23847622
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
PMID:21349428
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
PMID:17530315
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
PMID:24381786
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
PMID:18926762
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
PMID:21155715
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
PMID:22410872
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
PMID:12949498
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
PMID:12189384
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
PMID:26115564
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
PMID:23612460
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
PMID:22710174
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
KO pathway
ko04060   
LinkDB

DBGET integrated database retrieval system