KEGG   PATHWAY: cery04081
Entry
cery04081                   Pathway                                
Name
Hormone signaling - Chanodichthys erythropterus (predatory carp)
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
cery04081  Hormone signaling
cery04081

Organism
Chanodichthys erythropterus (predatory carp) [GN:cery]
Gene
137002015  thrb; thyroid hormone receptor beta isoform X1 [KO:K08362]
137002054  gngt1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
137002108  gnb3b; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3b [KO:K07825]
137002428  agtr1a; type-1 angiotensin II receptor B [KO:K04166]
137002482  gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1 [KO:K04543]
137002559  pth1r; parathyroid hormone/parathyroid hormone-related peptide receptor [KO:K04585]
137002561  [KO:K04579]
137002583  adcy8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
137002588  acvr1l; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
137002659  oprk1; kappa-type opioid receptor [KO:K04214]
137002739  insra; insulin receptor a isoform X1 [KO:K04527] [EC:2.7.10.1]
137002778  mc4r; melanocortin receptor 4 [KO:K04202]
137002819  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
137002840  gnb4a; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
137002841  adcy1b; adenylate cyclase type 1b [KO:K08041] [EC:4.6.1.1]
137002882  gng5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
137002962  thpo; thrombopoietin isoform X1 [KO:K06854]
137003108  adipoqb; adiponectin, C1Q and collagen domain containing, b isoform X1 [KO:K07296]
137003113  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
137003208  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
137003216  ghsra; growth hormone secretagogue receptor a [KO:K04284]
137003277  ghrhra; growth hormone releasing hormone receptor a [KO:K04589]
137003312  vipr1a; vasoactive intestinal polypeptide receptor [KO:K04589]
137003498  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
137003541  penka; proenkephalin a [KO:K18832]
137003897  gna11b; guanine nucleotide-binding protein subunit alpha-11b [KO:K04635]
137004124  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
137004283  [KO:K14735] [EC:1.16.3.1]
137004504  [KO:K04526]
137004541  [KO:K14735] [EC:1.16.3.1]
137004736  drd2a; dopamine receptor D2a isoform X1 [KO:K04145]
137004865  sst1.1; somatostatin 1, tandem duplicate 1 [KO:K05237]
137004887  [KO:K04139]
137004974  mlnr; growth hormone secretagogue receptor type 1 [KO:K05266]
137005064  sst1.2; somatostatin 1.2 [KO:K05237]
137005141  gipr; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
137005142  drd1a; D(1) dopamine receptor [KO:K04144]
137005303  si:dkey-202l22.3; 7 transmembrane receptor domain-containing protein [KO:K04314]
137005426  irs1; insulin receptor substrate 1-B isoform X1 [KO:K16172]
137006192  si:ch211-132f19.7; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
137006304  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
137006468  dio2; type II iodothyronine deiodinase [KO:K17904] [EC:1.21.99.4]
137006481  gnrh3; gonadotropin-releasing hormone 3 [KO:K05252]
137006531  pnoca; prepronociceptin [KO:K25696]
137006606  prlh2r; prolactin releasing hormone 2 receptor [KO:K04314]
137006616  pomca; proopiomelanocortin a isoform X1 [KO:K05228]
137006668  sstr1a; somatostatin receptor type 1 [KO:K04217]
137006817  [KO:K05840]
137007123  cga; glycoprotein hormones alpha chain [KO:K08522]
137007131  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
137007133  plcb4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
137007333  fshr; LOW QUALITY PROTEIN: follicle-stimulating hormone receptor [KO:K04247]
137007400  thrab; thyroid hormone receptor alpha isoform X1 [KO:K05547]
137007404  prkg1b; cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
137007419  stat5b; signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
137007436  itgb3b; integrin beta-3b [KO:K06493]
137007693  adrb1; beta-1 adrenergic receptor [KO:K04141]
137007840  gucy2cb; guanylyl cyclase C [KO:K12320] [EC:4.6.1.2]
137007841  [KO:K04218]
137007888  pth3r; parathyroid hormone 3 receptor [KO:K04585]
137007889  gna13a; guanine nucleotide-binding protein subunit alpha-13a [KO:K04639]
137007945  drd6b; D(5)-like dopamine receptor [KO:K05840]
137007981  sstr2a; somatostatin receptor type 2 [KO:K04218]
137008050  ghrhr2; growth hormone releasing hormone receptor 2 [KO:K04589]
137008184  gngt2b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2b [KO:K04549]
137008206  insb; LOW QUALITY PROTEIN: preproinsulin b [KO:K04526]
137008262  [KO:K05258]
137008263  [KO:K05258]
137008297  bmpr1ab; bone morphogenetic protein receptor, type IAb isoform X1 [KO:K04673] [EC:2.7.11.30]
137008322  [KO:K05258]
137008686  nppcl2; C-type natriuretic peptide 2 [KO:K12336]
137008711  src; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
137008719  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
137008787  [KO:K04216]
137008803  ghrhrl; growth hormone releasing hormone receptor, like [KO:K04584]
137008821  [KO:K12324] [EC:4.6.1.2]
137008924  [KO:K04284]
137008930  adcy6b; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
137009090  oprl1; nociceptin receptor isoform X1 [KO:K04216]
137009190  rapgef3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
137009397  epor; erythropoietin receptor [KO:K05079]
137009474  avpr2ab; vasopressin V2 receptor [KO:K04228]
137009524  pdyn; proenkephalin-B [KO:K15840]
137009572  [KO:K05251]
137009683  avpr2aa; vasopressin V2 receptor [KO:K04228]
137009787  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
137009798  rhoac; rho-related GTP-binding protein RhoA-C isoform X1 [KO:K04513]
137009886  adcy6a; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
137010254  mchr1b; melanin-concentrating hormone receptor 1 [KO:K04320]
137010630  gngt2a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2a [KO:K04549]
137010663  tshba; thyroid stimulating hormone subunit beta a [KO:K05251]
137010691  gh1; somatotropin [KO:K05438]
137010700  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
137010711  gnb1b; guanine nucleotide binding protein (G protein), beta polypeptide 1b [KO:K04536]
137010721  crhr1; corticotropin-releasing factor receptor 1 [KO:K04578]
137010733  oxtra; oxytocin receptor [KO:K04229]
137010759  lepr; leptin receptor isoform X1 [KO:K05062]
137010878  oxtrb; oxytocin receptor b [KO:K04229]
137010928  mpl; thrombopoietin receptor isoform X1 [KO:K05082]
137011010  avpr2b.1; oxytocin receptor [KO:K04228]
137011064  hcrt; orexin [KO:K05246]
137011321  rhoca; ras homolog family member Ca [KO:K04513]
137011358  ghrhrb; vasoactive intestinal polypeptide receptor 1 [KO:K04589]
137011370  ghrl; ghrelin/obestatin prepropeptide [KO:K05254]
137011408  sstr3; somatostatin receptor type 5 [KO:K04219]
137011617  gnai2b; guanine nucleotide-binding protein G(i) subunit alpha-2b [KO:K04630]
137011635  mchr1a; melanin-concentrating hormone receptor 1 [KO:K04320]
137011685  si:zfos-169g10.2; somatostatin receptor type 5 [KO:K04219]
137011695  gnas; guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632]
137011727  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
137011736  rapgef4b; rap guanine nucleotide exchange factor 4-like [KO:K04351]
137012056  jak2a; tyrosine-protein kinase JAK2a isoform X1 [KO:K04447] [EC:2.7.10.2]
137012086  si:dkey-204f11.64; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04542]
137012186  gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
137012252  gng13b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13b [KO:K04547]
137012512  gnrh2; progonadoliberin-2 [KO:K05252]
137012518  adrb2b; adrenoceptor beta 2, surface b [KO:K04142]
137012632  gng8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
137012711  gper1; G-protein coupled estrogen receptor 1 [KO:K04246]
137012773  adra1ba; alpha-1A adrenergic receptor [KO:K04136]
137012880  drd1b; dopamine receptor D1b [KO:K04144]
137012945  prlra; prolactin receptor a [KO:K05081]
137013040  adra2db; alpha-2Db adrenergic receptor [KO:K04140]
137013086  irs4a; insulin receptor substrate 2-B [KO:K07187]
137013420  crhb; corticotropin releasing hormone b [KO:K05256]
137013516  vipr1b; vasoactive intestinal polypeptide receptor 1b [KO:K04589]
137013560  [KO:K04246]
137013596  drd3; D(3) dopamine receptor [KO:K04146]
137013628  sstr2b; somatostatin receptor type 2 [KO:K04218]
137013791  adipoqa; adiponectin [KO:K07296]
137013877  vipr2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
137013965  [KO:K08449]
137014031  ghsrb; growth hormone secretagogue receptor type 1 [KO:K04284]
137014137  [KO:K08447]
137014328  agtr1b; type-1 angiotensin II receptor A [KO:K04166]
137014372  prlh2; prolactin releasing hormone 2 [KO:K05269]
137014625  gnb5a; guanine nucleotide-binding protein subunit beta-5a [KO:K04539]
137014663  igf2b; insulin-like growth factor 2b [KO:K13769]
137014878  drd4a; dopamine receptor D4a isoform X1 [KO:K04147]
137015018  avpr1aa; arginine vasopressin receptor 1Aa [KO:K04226]
137015312  [KO:K12332]
137015570  gnaia; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a [KO:K04630]
137015586  pthlhb; parathyroid hormone-like hormone b [KO:K22608]
137017134  gucy2ca; guanylyl cyclase C [KO:K12320] [EC:4.6.1.2]
137017251  [KO:K08049] [EC:4.6.1.1]
137017276  sstr5; somatostatin receptor type 5 [KO:K04221]
137017302  gcgra; glucagon receptor isoform X1 [KO:K04583]
137017306  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [KO:K04345] [EC:2.7.11.11]
137017442  itgb3a; integrin beta-3a isoform X1 [KO:K06493]
137017486  stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
137017689  ramp2; receptor activity-modifying protein 2 [KO:K08448]
137017705  gna13b; guanine nucleotide-binding protein subunit alpha-13b [KO:K04639]
137017730  thraa; thyroid hormone receptor alpha-A isoform X1 [KO:K05547]
137017790  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
137018463  pnocb; prepronociceptin b [KO:K25696]
137018533  pomcb; proopiomelanocortin b [KO:K05228]
137018534  si:dkey-206f10.1; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
137018599  [KO:K08043] [EC:4.6.1.1]
137018759  adcy1a; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
137018766  slc16a2; monocarboxylate transporter 8 [KO:K08231]
137018824  prkg3; cGMP-dependent protein kinase 1 [KO:K19477] [EC:2.7.11.12]
137018847  adra2da; alpha-2Da adrenergic receptor [KO:K04140]
137018870  esr2a; estrogen receptor 2a isoform X1 [KO:K08551]
137018962  esr1; estrogen receptor isoform X1 [KO:K08550]
137019093  drd5a; D(1B) dopamine receptor [KO:K05840]
137019134  uts1; urotensin 1 [KO:K23142]
137019294  plcb4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
137019295  plcb1l; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
137019324  tshr; thyrotropin receptor [KO:K04249]
137019439  slc16a10; monocarboxylate transporter 10 [KO:K08187]
137019913  vip; VIP peptides [KO:K05264]
137019922  [KO:K04541]
137019990  [KO:K19477] [EC:2.7.11.12]
137020051  [KO:K04215]
137020193  lhb; lutropin subunit beta [KO:K08521]
137020203  hcrtr2; orexin receptor type 2 [KO:K04239]
137020236  smad5; mothers against decapentaplegic homolog 5 [KO:K16790]
137020294  lhcgr; lutropin-choriogonadotropic hormone receptor [KO:K04248]
137020344  gng2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
137020504  bmpr1aa; bone morphogenetic protein receptor, type IAa isoform X1 [KO:K04673] [EC:2.7.11.30]
137020525  agt; angiotensinogen [KO:K09821]
137020730  esr2b; estrogen receptor 2b isoform X1 [KO:K08551]
137020863  prkg1a; cGMP-dependent protein kinase 1a isoform X1 [KO:K07376] [EC:2.7.11.12]
137020920  vipb; vasoactive intestinal peptide b isoform X1 [KO:K05264]
137020939  appl1; DCC-interacting protein 13-alpha isoform X1 [KO:K08733]
137021056  si:ch211-220m17.5; guanylin family protein [KO:K25556]
137021057  [KO:K25556]
137021272  [KO:K05260]
137021274  [KO:K05260]
137021350  gnb4b; guanine nucleotide binding protein (G protein), beta polypeptide 4b [KO:K04538]
137021360  adrb2a; adrenoceptor beta 2, surface a [KO:K04142]
137021457  gnai2a; guanine nucleotide-binding protein G(i) subunit alpha-2a isoform X1 [KO:K04630]
137021461  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
137021549  adipor1a; adiponectin receptor protein 1a [KO:K07297]
137021706  prkacba; protein kinase, cAMP-dependent, catalytic, beta a [KO:K04345] [EC:2.7.11.11]
137021723  adra1bb; adrenoceptor alpha 1Bb [KO:K04136]
137022539  smtla; somatolactin alpha [KO:K05438]
137022603  gnb5b; guanine nucleotide-binding protein subunit beta-5b isoform X1 [KO:K04539]
137022644  mc1r; melanocyte-stimulating hormone receptor [KO:K04199]
137022798  trhr2; thyrotropin releasing hormone receptor 2 [KO:K04282]
137022812  mchr2b; melanin concentrating hormone receptor 2b [KO:K05054]
137022862  gnrhr4; gonadotropin releasing hormone receptor 4 [KO:K04280]
137023249  lepa; leptin a [KO:K05424]
137023373  igf1ra; insulin-like growth factor 1a receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
137023397  gnao1a; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a isoform X1 [KO:K04534]
137023742  pthlha; parathyroid hormone-like hormone a [KO:K22608]
137023807  avpr1ab; arginine vasopressin receptor 1Ab [KO:K04226]
137023893  prl2; prolactin 2 [KO:K05439]
137023908  ucn3l; urocortin 3, like [KO:K05257]
137023926  pmch; pro-MCH [KO:K05229]
137023937  avpr2l; arginine vasopressin receptor 2, like [KO:K04228]
137023942  lepb; leptin b [KO:K05424]
137023947  drd4-rs; dopamine receptor D4 related sequence [KO:K04147]
137023978  [KO:K08039]
137023979  [KO:K08747]
137024190  slco1c1; solute carrier organic anion transporter family member 1C1 [KO:K08747]
137024255  adipor2; adiponectin receptor protein 2 [KO:K07297]
137024432  igf1; insulin-like growth factor I [KO:K05459]
137024555  gnai1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
137024612  slco1e1; solute carrier organic anion transporter family member 1C1 [KO:K08747]
137024613  slco1d1; solute carrier organic anion transporter family, member 1D1 [KO:K08747]
137024677  adcy2a; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
137024789  ccka; cholecystokinin a [KO:K05226]
137024958  [KO:K08747]
137025208  si:ch211-254p10.2; ferroportin [KO:K14685]
137025842  gnb3a; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3a [KO:K07825]
137026184  avp; vasopressin-neurophysin 2-copeptin [KO:K05242]
137026311  dio1; type I iodothyronine deiodinase isoform X1 [KO:K01562] [EC:1.21.99.4]
137026418  mc3r; melanocortin receptor 3 [KO:K04201]
137026497  trhra; thyrotropin-releasing hormone receptor [KO:K04282]
137026561  adra2b; alpha-2B adrenergic receptor [KO:K04139]
137026584  prlhr2a; prolactin releasing hormone receptor 2a [KO:K04314]
137026624  nppa; natriuretic peptides A [KO:K12334]
137026626  nppal; natriuretic peptide A-like [KO:K12336]
137026709  trh; pro-thyrotropin-releasing hormone [KO:K05253]
137026746  [KO:K05243]
137026795  mchr2a; melanin-concentrating hormone receptor 2 [KO:K05054]
137026821  adra1aa; adrenoceptor alpha 1Aa isoform X1 [KO:K04135]
137026918  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
137027063  ghra; growth hormone receptor a [KO:K05080]
137027099  adipor1b; adiponectin receptor protein 1b [KO:K07297]
137027114  rhocb; rho-related GTP-binding protein RhoA-D [KO:K04513]
137027133  gnai3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
137027153  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
137027270  adrb3a; adrenoceptor beta 3a [KO:K04143]
137027359  gna14a; guanine nucleotide-binding protein subunit alpha-14 [KO:K04636]
137027381  gnb1a; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
137027419  [KO:K04282]
137027561  pth4; parathyroid hormone 4 [KO:K22608]
137027750  amh; muellerian-inhibiting factor [KO:K04665]
137027768  gna11a; guanine nucleotide-binding protein subunit alpha-11a isoform X1 [KO:K04634]
137027770  [KO:K04637]
137027823  adcy9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
137027851  [KO:K04527] [EC:2.7.10.1]
137028142  [KO:K12324] [EC:4.6.1.2]
137028288  [KO:K04139]
137028361  hephl1b; ferroxidase HEPHL1 [KO:K14735] [EC:1.16.3.1]
137028389  adra1ab; alpha-1A adrenergic receptor [KO:K04135]
137028439  [KO:K04513]
137028476  smad4a; mothers against decapentaplegic homolog 4a isoform X1 [KO:K04501]
137028480  bmpr1bb; bone morphogenetic protein receptor, type IBb [KO:K13578] [EC:2.7.11.30]
137028594  adrb3b; adrenoceptor beta 3b [KO:K04143]
137028666  smad9; mothers against decapentaplegic homolog 9 isoform X1 [KO:K16791]
137028845  gnrhr3; gonadotropin releasing hormone receptor 3 isoform X1 [KO:K04280]
137029007  nppc; C-type natriuretic peptide [KO:K12336]
137029038  adra2a; alpha-2A adrenergic receptor [KO:K04138]
137029451  [KO:K07376] [EC:2.7.11.12]
137029477  prlhr2b; prolactin releasing hormone receptor 2b [KO:K04314]
137029657  drd2l; dopamine receptor D2 like [KO:K04145]
137029701  epob; erythropoietin b [KO:K05437]
137029986  adcy3a; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
137030271  epoa; erythropoietin isoform X1 [KO:K05437]
137030288  cckar; cholecystokinin receptor type A [KO:K04194]
137030324  igf2a; insulin-like growth factor 2a isoform X1 [KO:K13769]
137030494  gnao1b; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b [KO:K04534]
137030525  calca; calcitonin/calcitonin-related polypeptide, alpha isoform X1 [KO:K12332]
137030550  sstr1b; somatostatin receptor type 1 [KO:K04217]
137030714  gnrhr2; gonadotropin releasing hormone receptor 2 [KO:K04280]
137030840  igf1rb; insulin-like growth factor 1b receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
137030977  drd4b; dopamine receptor D4b [KO:K04147]
137031008  penkb; proenkephalin b [KO:K18832]
137031088  sst5; somatostatin-1A [KO:K05237]
137031154  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
137031157  pth1b; parathyroid hormone 1b [KO:K05261]
137031178  [KO:K07187]
137031340  adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
137031811  gcgrb; glucagon receptor isoform X1 [KO:K04583]
137031819  smad1; mothers against decapentaplegic homolog 1 isoform X1 [KO:K04676]
137031972  gng13a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13a [KO:K04547]
137032045  irs2a; insulin receptor substrate 2a [KO:K07187]
137032192  [KO:K05080]
137032232  adra2c; alpha-2C adrenergic receptor [KO:K04140]
137032252  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
137032676  [KO:K05840]
137032704  si:ch211-286b5.5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
137032708  cckbra; cholecystokinin receptor-like [KO:K04194]
137032814  [KO:K04221]
137032899  adra1d; alpha-1A adrenergic receptor [KO:K04137]
137033562  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
137033605  bmpr1ba; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
137033643  gnaq; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
137033654  oprd1b; opioid receptor, delta 1b [KO:K04213]
137033749  gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
137033796  gna14; guanine nucleotide-binding protein subunit alpha-14 [KO:K04636]
137033824  prkg2; cGMP-dependent protein kinase 2 isoform X1 [KO:K19477] [EC:2.7.11.12]
137033925  oxt; oxytocin-neurophysin 1 [KO:K05243]
137033938  smad4b; mothers against decapentaplegic homolog 4 [KO:K04501]
137033951  gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
137034063  drd2b; dopamine receptor D2b isoform X1 [KO:K04145]
137034159  drd7; dopamine receptor D7 [KO:K05840]
137034266  mc5rb; melanocortin 5b receptor [KO:K04203]
137034273  mc2r; adrenocorticotropic hormone receptor [KO:K04200]
137034312  npr3; atrial natriuretic peptide receptor 3 isoform X1 [KO:K12325]
137034359  npr2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
137034409  ins; insulin [KO:K04526]
137034657  npr1b; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
137034677  smad10b; mothers against decapentaplegic homolog 4 [KO:K04501]
137034977  agtr2; type-2 angiotensin II receptor [KO:K04167]
137035124  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
137035134  jak2b; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
137035338  itgav; integrin alpha-V [KO:K06487]
137035371  [KO:K04675] [EC:2.7.11.30]
137035387  adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
137035568  rapgef4a; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
137035666  prlh; prolactin-releasing peptide [KO:K05269]
137035921  slc40a1; solute carrier family 40 member 1 isoform X1 [KO:K14685]
137036010  ramp1; receptor activity-modifying protein 1 [KO:K08447]
137036037  gcgb; glucagon b [KO:K05259]
137036051  cckbrb; cholecystokinin receptor [KO:K04194]
137036496  irs2b; insulin receptor substrate 2 [KO:K07187]
137037247  smad10a; mothers against decapentaplegic homolog 4 [KO:K04501]
137037312  gnrhr1; gonadotropin releasing hormone receptor 1 [KO:K04280]
137037442  mc5ra; melanocortin 5a receptor [KO:K04203]
137037556  oprd1a; opioid receptor, delta 1a [KO:K04213]
137037621  calcr; calcitonin gene-related peptide type 1 receptor [KO:K04576]
137037626  npr1a; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
137037709  adcy2b; adenylate cyclase type 2b isoform X1 [KO:K08042] [EC:4.6.1.1]
137037714  hamp; hepcidin-1 isoform X1 [KO:K23106]
137037762  cckb; cholecystokinin [KO:K05226]
137037809  trhrb; thyrotropin-releasing hormone receptor b [KO:K04282]
Compound
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00788  L-Adrenaline
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01829  Thyroxine
C02017  Corticotropin
C02210  beta-Endorphin
C02465  Triiodothyronine
C02758  alpha-Melanotropin
C03758  Dopamine
C14818  Fe2+
C14819  Fe3+
C16000  Urodilatin
C16048  Glucagon-like peptide 1
C16125  Calcitonin gene-related peptide 1
C16126  Calcitonin gene-related peptide 2
C16136  beta-Melanotropin
C16137  gamma-Melanotropin
Reference
  Authors
Trubacova R, Drastichova Z, Novotny J
  Title
Biochemical and physiological insights into TRH receptor-mediated signaling.
  Journal
Front Cell Dev Biol 10:981452 (2022)
DOI:10.3389/fcell.2022.981452
Reference
  Authors
Velez EJ, Unniappan S
  Title
A Comparative Update on the Neuroendocrine Regulation of Growth Hormone in Vertebrates.
  Journal
Front Endocrinol (Lausanne) 11:614981 (2020)
DOI:10.3389/fendo.2020.614981
Reference
  Authors
Kumar U
  Title
Somatostatin and Somatostatin Receptors in Tumour Biology.
  Journal
Int J Mol Sci 25:ijms25010436 (2023)
DOI:10.3390/ijms25010436
Reference
  Authors
Kahnamouyi S, Nouri M, Farzadi L, Darabi M, Hosseini V, Mehdizadeh A
  Title
The role of mitogen-activated protein kinase-extracellular receptor kinase pathway in female fertility outcomes: a focus on pituitary gonadotropins  regulation.
  Journal
Ther Adv Endocrinol Metab 9:209-215 (2018)
DOI:10.1177/2042018818772775
Reference
  Authors
Deussing JM, Chen A
  Title
The Corticotropin-Releasing Factor Family: Physiology of the Stress Response.
  Journal
Physiol Rev 98:2225-2286 (2018)
DOI:10.1152/physrev.00042.2017
Reference
  Authors
Li Y, Yuan Q, He X, Zhang Y, You C, Wu C, Li J, Xu HE, Zhao LH
  Title
Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
  Journal
Cell Discov 10:91 (2024)
DOI:10.1038/s41421-024-00724-6
Reference
  Authors
Wang C, Wang Q, Ji B, Pan Y, Xu C, Cheng B, Bai B, Chen J
  Title
The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.
  Journal
Front Mol Neurosci 11:220 (2018)
DOI:10.3389/fnmol.2018.00220
Reference
  Authors
Bencze J, Pocsai K, Murnyak B, Gergely PA, Juhasz B, Szilvassy Z, Hortobagyi T
  Title
The Melanin-concentrating Hormone System in Human, Rodent and Avian Brain.
  Journal
Open Med (Wars) 13:264-269 (2018)
DOI:10.1515/med-2018-0040
Reference
  Authors
Lin YT, Hsu KS
  Title
Oxytocin receptor signaling in the hippocampus: Role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social  memory.
  Journal
Prog Neurobiol 171:1-14 (2018)
DOI:10.1016/j.pneurobio.2018.10.003
Reference
  Authors
Perisic M, Woolcock K, Hering A, Mendel H, Muttenthaler M
  Title
Oxytocin and vasopressin signaling in health and disease.
  Journal
Trends Biochem Sci 49:361-377 (2024)
DOI:10.1016/j.tibs.2024.01.010
Reference
  Authors
Che T, Roth BL
  Title
Molecular basis of opioid receptor signaling.
  Journal
Cell 186:5203-5219 (2023)
DOI:10.1016/j.cell.2023.10.029
Reference
  Authors
Jing L, Zhang Q
  Title
Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion.
  Journal
Front Endocrinol (Lausanne) 13:992883 (2022)
DOI:10.3389/fendo.2022.992883
Reference
  Authors
Hu B, Li H, Zhang X
  Title
A Balanced Act: The Effects of GH-GHR-IGF1 Axis on Mitochondrial Function.
  Journal
Front Cell Dev Biol 9:630248 (2021)
DOI:10.3389/fcell.2021.630248
Reference
  Authors
Gloaguen P, Crepieux P, Heitzler D, Poupon A, Reiter E
  Title
Mapping the follicle-stimulating hormone-induced signaling networks.
  Journal
Front Endocrinol (Lausanne) 2:45 (2011)
DOI:10.3389/fendo.2011.00045
Reference
  Authors
Johnson GP, Jonas KC
  Title
Mechanistic insight into how gonadotropin hormone receptor complexes direct signalingdagger.
  Journal
Biol Reprod 102:773-783 (2020)
DOI:10.1093/biolre/ioz228
Reference
  Authors
Wu CS, Cioanca AV, Gelmi MC, Wen L, Di Girolamo N, Zhu L, Natoli R, Conway RM, Petsoglou C, Jager MJ, McCluskey PJ, Madigan MC
  Title
The multifunctional human ocular melanocortin system.
  Journal
Prog Retin Eye Res 95:101187 (2023)
DOI:10.1016/j.preteyeres.2023.101187
Reference
  Authors
Standing D, Dandawate P, Anant S
  Title
Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies.
  Journal
Front Endocrinol (Lausanne) 13:1112987 (2022)
DOI:10.3389/fendo.2022.1112987
Reference
  Authors
Mendoza A, Hollenberg AN
  Title
New insights into thyroid hormone action.
  Journal
Pharmacol Ther 173:135-145 (2017)
DOI:10.1016/j.pharmthera.2017.02.012
Reference
  Authors
Gupta P, Furness SGB, Bittencourt L, Hare DL, Wookey PJ
  Title
Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma.
  Journal
Ther Adv Med Oncol 12:1758835920978110 (2020)
DOI:10.1177/1758835920978110
Reference
  Authors
Lombardi G, Ziemann E, Banfi G, Corbetta S
  Title
Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.
  Journal
Int J Mol Sci 21:ijms21155388 (2020)
DOI:10.3390/ijms21155388
Reference
  Authors
Mani I, Pandey KN
  Title
Emerging concepts of receptor endocytosis and concurrent intracellular signaling: Mechanisms of guanylyl cyclase/natriuretic peptide receptor-A activation and  trafficking.
  Journal
Cell Signal 60:17-30 (2019)
DOI:10.1016/j.cellsig.2019.03.022
Reference
  Authors
Perez DM
  Title
alpha(1)-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition.
  Journal
Front Pharmacol 11:581098 (2020)
DOI:10.3389/fphar.2020.581098
Reference
  Authors
Feng Y, Lu Y
  Title
Immunomodulatory Effects of Dopamine in Inflammatory Diseases.
  Journal
Front Immunol 12:663102 (2021)
DOI:10.3389/fimmu.2021.663102
Reference
  Authors
Colin M, Delaitre C, Foulquier S, Dupuis F
  Title
The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System.
  Journal
Molecules 28:molecules28145481 (2023)
DOI:10.3390/molecules28145481
Reference
  Authors
Bogdan AR, Miyazawa M, Hashimoto K, Tsuji Y
  Title
Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.
  Journal
Trends Biochem Sci 41:274-86 (2016)
DOI:10.1016/j.tibs.2015.11.012
Reference
  Authors
Rajoria B, Zhang X, Yee D
  Title
IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells.
  Journal
Int J Mol Sci 24:ijms241210209 (2023)
DOI:10.3390/ijms241210209
Reference
  Authors
Arneth B, Arneth R, Shams M
  Title
Metabolomics of Type 1 and Type 2 Diabetes.
  Journal
Int J Mol Sci 20:ijms20102467 (2019)
DOI:10.3390/ijms20102467
Reference
  Authors
Kajani S, Laker RC, Ratkova E, Will S, Rhodes CJ
  Title
Hepatic glucagon action: beyond glucose mobilization.
  Journal
Physiol Rev 104:1021-1060 (2024)
DOI:10.1152/physrev.00028.2023
Reference
  Authors
Silvestro M, Iannone LF, Orologio I, Tessitore A, Tedeschi G, Geppetti P, Russo A
  Title
Migraine Treatment: Towards New Pharmacological Targets.
  Journal
Int J Mol Sci 24:ijms241512268 (2023)
DOI:10.3390/ijms241512268
Reference
  Authors
Elliott S, Sinclair A, Collins H, Rice L, Jelkmann W
  Title
Progress in detecting cell-surface protein receptors: the erythropoietin receptor example.
  Journal
Ann Hematol 93:181-92 (2014)
DOI:10.1007/s00277-013-1947-2
Reference
  Authors
van Loenen MR, Geenen B, Arnoldussen IAC, Kiliaan AJ
  Title
Ghrelin as a prominent endocrine factor in stress-induced obesity.
  Journal
Nutr Neurosci 25:1413-1424 (2022)
DOI:10.1080/1028415X.2020.1863740
Reference
  Authors
Zeng Q, Ou L, Wang W, Guo DY
  Title
Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes.
  Journal
Front Endocrinol (Lausanne) 11:112 (2020)
DOI:10.3389/fendo.2020.00112
Reference
  Authors
Takei Y
  Title
Evolution of the membrane/particulate guanylyl cyclase: From physicochemical sensors to hormone receptors.
  Journal
Gen Comp Endocrinol 315:113797 (2022)
DOI:10.1016/j.ygcen.2021.113797
Reference
  Authors
Seino Y, Fukushima M, Yabe D
  Title
GIP and GLP-1, the two incretin hormones: Similarities and differences.
  Journal
J Diabetes Investig 1:8-23 (2010)
DOI:10.1111/j.2040-1124.2010.00022.x
Reference
  Authors
Langer I, Jeandriens J, Couvineau A, Sanmukh S, Latek D
  Title
Signal Transduction by VIP and PACAP Receptors.
  Journal
Biomedicines 10:biomedicines10020406 (2022)
DOI:10.3390/biomedicines10020406
Reference
  Authors
Kitazawa T, Kaiya H
  Title
Motilin Comparative Study: Structure, Distribution, Receptors, and Gastrointestinal Motility.
  Journal
Front Endocrinol (Lausanne) 12:700884 (2021)
DOI:10.3389/fendo.2021.700884
Reference
  Authors
Cate RL
  Title
Anti-Mullerian Hormone Signal Transduction involved in Mullerian Duct Regression.
  Journal
Front Endocrinol (Lausanne) 13:905324 (2022)
DOI:10.3389/fendo.2022.905324
Reference
  Authors
Rettberg JR, Yao J, Brinton RD
  Title
Estrogen: a master regulator of bioenergetic systems in the brain and body.
  Journal
Front Neuroendocrinol 35:8-30 (2014)
DOI:10.1016/j.yfrne.2013.08.001
Reference
  Authors
Prossnitz ER, Barton M
  Title
The G protein-coupled oestrogen receptor GPER in health and disease: an update.
  Journal
Nat Rev Endocrinol 19:407-424 (2023)
DOI:10.1038/s41574-023-00822-7
Reference
  Authors
Roy B, Palaniyandi SS
  Title
Tissue-specific role and associated downstream signaling pathways of adiponectin.
  Journal
Cell Biosci 11:77 (2021)
DOI:10.1186/s13578-021-00587-4
Reference
  Authors
Liu J, Lai F, Hou Y, Zheng R
  Title
Leptin signaling and leptin resistance.
  Journal
Med Rev (2021) 2:363-384 (2022)
DOI:10.1515/mr-2022-0017
Reference
  Authors
Kuter DJ
  Title
Treatment of chemotherapy-induced thrombocytopenia in patients with non-hematologic malignancies.
  Journal
Haematologica 107:1243-1263 (2022)
DOI:10.3324/haematol.2021.279512
Related
pathway
cery04020  Calcium signaling pathway
KO pathway
ko04081   

DBGET integrated database retrieval system