KEGG   PATHWAY: ocu04820
Entry
ocu04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Oryctolagus cuniculus (rabbit)
Class
Cellular Processes; Cell motility
Pathway map
ocu04820  Cytoskeleton in muscle cells
ocu04820

Organism
Oryctolagus cuniculus (rabbit) [GN:ocu]
Gene
100008570  TTN; titin isoform X1 [KO:K12567] [EC:2.7.11.1]
100008642  [KO:K06485]
100008663  BGN; biglycan precursor [KO:K08118]
100008666  [KO:K06793]
100008687  [KO:K24220]
100008714  SSPN; sarcospan [KO:K22194]
100008719  ANKRD1; ankyrin repeat domain-containing protein 1 [KO:K21433]
100008726  CAPN3; calpain-3 [KO:K08573] [EC:3.4.22.54]
100008734  ITGA2B; integrin alpha-IIb precursor [KO:K06476]
100008735  ITGB3; integrin beta-3 precursor [KO:K06493]
100008749  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
100008756  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
100008769  ENO3; beta-enolase [KO:K01689] [EC:4.2.1.11]
100008787  [KO:K19721]
100008788  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
100008822  [KO:K05692]
100008898  [KO:K05719]
100008924  [KO:K07606]
100008956  [KO:K06487]
100008997  COL1A2; collagen alpha-2(I) chain precursor [KO:K06236]
100009001  [KO:K10352]
100009002  [KO:K10352]
100009016  MYOZ1; myozenin-1 [KO:K26050]
100009141  ITGB8; integrin beta-8 precursor [KO:K06591]
100009145  MYH11; myosin-11 [KO:K10352]
100009171  DCN; decorin precursor [KO:K04660]
100009172  [KO:K06484]
100009177  [KO:K19720]
100009178  SGCA; alpha-sarcoglycan precursor [KO:K12565]
100009179  SNTA1; alpha-1-syntrophin [KO:K24063]
100009208  SGCB; beta-sarcoglycan [KO:K12566]
100009214  SGCG; gamma-sarcoglycan [KO:K12564]
100009272  ACTB; actin, cytoplasmic 1 [KO:K05692]
100009278  DAG1; dystroglycan 1 precursor [KO:K06265]
100009341  TNNC2; troponin C, skeletal muscle [KO:K12042]
100009400  MYL1; myosin light chain 1/3, skeletal muscle isoform [KO:K05738]
100009406  MYH3; myosin-3 [KO:K24220]
100009506  [KO:K10354]
100009542  MYL11; myosin regulatory light chain 2, skeletal muscle isoform type 2 [KO:K12758]
100009544  [KO:K21073]
100009548  [KO:K24220]
100009577  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
100101566  MYH7; myosin-7 [KO:K17751]
100101587  [KO:K06525]
100101621  [KO:K06481]
100125984  TPM2; tropomyosin beta chain [KO:K10374]
100125987  MYH6; myosin-6 [KO:K17751]
100125989  TPM1; tropomyosin alpha-1 chain [KO:K10373]
100125991  MYH4; myosin-4 [KO:K24220]
100126568  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
100302407  MYH13; myosin-13 [KO:K24220]
100302415  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
100303760  [KO:K24220]
100328572  NEB; nebulin isoform X1 [KO:K18267]
100328589  FN1; fibronectin isoform X1 [KO:K05717]
100328666  TMOD4; tropomodulin-4 [KO:K10370]
100328722  PDLIM4; PDZ and LIM domain protein 4 [KO:K23353]
100328755  EMD; emerin [KO:K12569]
100328890  DES; desmin [KO:K07610]
100337715  [KO:K23957]
100337828  [KO:K10371]
100337959  [KO:K14380]
100338081  [KO:K10370]
100338232  [KO:K06589]
100338437  [KO:K06237]
100338470  [KO:K06257]
100338720  [KO:K06115]
100338915  [KO:K08131]
100338925  [KO:K24494]
100339026  [KO:K24414]
100339422  [KO:K23957]
100339581  [KO:K10370]
100339625  [KO:K06585]
100339915  [KO:K06238]
100340248  [KO:K06586]
100340249  [KO:K01490] [EC:3.5.4.6]
100340334  [KO:K06255]
100340339  [KO:K12314]
100340402  [KO:K22030]
100340417  [KO:K06238]
100340474  [KO:K04512]
100340506  SDC3; syndecan-3 [KO:K16337]
100340750  [KO:K19721]
100340815  [KO:K08131]
100341020  [KO:K24494]
100341037  [KO:K05692]
100341289  [KO:K06115]
100341968  [KO:K28413]
100342024  [KO:K10654]
100342347  [KO:K06115]
100342711  [KO:K06480]
100343175  [KO:K10375]
100343234  [KO:K25865]
100343384  [KO:K12755]
100343541  [KO:K23353]
100343574  [KO:K12641]
100343769  [KO:K24495]
100343910  [KO:K04659]
100343947  [KO:K06238]
100344050  [KO:K19875]
100344251  [KO:K06587]
100344271  [KO:K14211]
100344490  [KO:K01490] [EC:3.5.4.6]
100344572  [KO:K07601]
100344809  [KO:K26050]
100344823  [KO:K05745]
100345014  [KO:K19532] [EC:1.3.1.70]
100345384  [KO:K19721]
100345621  [KO:K12750]
100345709  [KO:K10056]
100345952  [KO:K10365]
100346005  [KO:K06583]
100346020  [KO:K27488]
100346094  [KO:K07611]
100346103  [KO:K06483]
100346489  [KO:K19346]
100346596  [KO:K17531] [EC:2.7.11.1]
100346773  [KO:K12568]
100347054  [KO:K23957]
100347154  [KO:K24495]
100347164  [KO:K10655] [EC:2.3.2.27]
100347243  [KO:K04512]
100347379  [KO:K17307]
100347570  [KO:K05865]
100347598  [KO:K06236]
100347682  [KO:K06826]
100347738  [KO:K12642]
100347740  [KO:K12749]
100347806  [KO:K21438]
100347936  [KO:K05741]
100348062  [KO:K22030]
100348149  [KO:K07597]
100348317  [KO:K27381]
100348592  [KO:K22028]
100348594  [KO:K06482]
100348816  [KO:K09377]
100348821  [KO:K06273]
100348927  [KO:K19867]
100348989  [KO:K01689] [EC:4.2.1.11]
100349129  [KO:K10388]
100349216  [KO:K09377]
100349335  [KO:K10364]
100349382  [KO:K01539] [EC:7.2.2.13]
100349413  [KO:K19721]
100349537  [KO:K27062]
100349893  [KO:K09290]
100350113  [KO:K01540]
100350274  [KO:K21073]
100350318  [KO:K12315]
100350430  [KO:K16857]
100350500  [KO:K05637]
100350557  [KO:K06590]
100350566  [KO:K17307]
100350866  [KO:K06114]
100350931  [KO:K06825]
100351025  [KO:K06826]
100351181  [KO:K06584]
100351233  [KO:K12563]
100351412  [KO:K26998]
100351420  [KO:K09290]
100351728  [KO:K10653]
100351774  [KO:K19867]
100351873  [KO:K10364]
100351884  [KO:K01490] [EC:3.5.4.6]
100352283  [KO:K23353]
100352334  [KO:K27061]
100352426  [KO:K01689] [EC:4.2.1.11]
100352444  [KO:K21434]
100352455  [KO:K16338]
100352989  [KO:K21761]
100353069  [KO:K23353]
100353296  [KO:K09259]
100353304  [KO:K10351]
100353416  [KO:K12557]
100353546  [KO:K06588]
100353619  [KO:K24066]
100353671  [KO:K27393]
100353864  [KO:K26050]
100354169  [KO:K05740]
100354205  [KO:K09255]
100354375  [KO:K06271]
100354434  [KO:K10381]
100354450  [KO:K24220]
100354514  [KO:K24064]
100355265  [KO:K23932]
100355386  [KO:K19721]
100355526  [KO:K16336]
100355647  [KO:K19879]
100355653  [KO:K19721]
100355731  [KO:K10366]
100356178  [KO:K24220]
100356313  [KO:K02184]
100356474  [KO:K06238]
100356893  [KO:K24495]
100357126  [KO:K23342]
100357137  [KO:K04659]
100357160  [KO:K05700]
100357207  [KO:K12558]
100357263  [KO:K14365]
100357427  [KO:K06237]
100357482  [KO:K05637]
100357577  [KO:K27381]
100357898  [KO:K19867]
100357900  [KO:K06237]
100357972  [KO:K04659]
100358093  [KO:K10364]
100358220  [KO:K10370]
100358256  [KO:K06237]
100358269  [KO:K01539] [EC:7.2.2.13]
100358282  [KO:K22030]
100358522  [KO:K06237]
100358638  [KO:K24421]
100358920  [KO:K06271]
100358973  [KO:K09377]
100359303  [KO:K10370]
100359336  [KO:K23342]
103345754  [KO:K06238]
103347091  [KO:K19347]
103347121  [KO:K06254]
103348163  [KO:K10365]
103348391  [KO:K19347]
103348511  [KO:K24064]
103349793  [KO:K08131]
103350383  [KO:K06585]
103351027  [KO:K23958]
108176892  [KO:K06237]
108177489  [KO:K19326]
127487418  [KO:K06583]
127492634  [KO:K12754]
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
ocu04512  ECM-receptor interaction
ocu04814  Motor proteins
KO pathway
ko04820   

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