KEGG   PATHWAY: gsj03013
Entry
gsj03013                    Pathway                                
Name
Nucleocytoplasmic transport - Glycine soja (wild soybean)
Description
The exchange of molecules between the nucleus and cytoplasm is mediated through nuclear pore complexes (NPCs) embedded in the nuclear envelope. The NPC is composed of highly conserved, distinct structural modules: the inner pore ring, the cytoplasmic and nuclear rings as well as the cytoplasmic filaments and the nuclear basket. Nuclear transport receptors (e.g. importins and exportins) mediate translocation of cargos through the NPC. Cargo proteins harbouring a nuclear export signal (NES) bind to exportins and Ran-GTP to form an export complex in the nucleoplasm. Nuclear export of bulk mRNA is provided by the non-karyopherin transport proteins TAP-p15 in a Ran-GTP-independent manner. Several EJC factors are known to function in mRNA export.
Class
Genetic Information Processing; Translation
Pathway map
gsj03013  Nucleocytoplasmic transport
gsj03013

Other DBs
GO: 0050658
Organism
Glycine soja (wild soybean) [GN:gsj]
Gene
114406579  aladin-like isoform X1 [KO:K14320]
114398373  aladin-like [KO:K14320]
114380480  zinc finger CCCH domain-containing protein 16-like isoform X1 [KO:K14321]
114377675  zinc finger CCCH domain-containing protein 16-like isoform X1 [KO:K14321]
114381828  protein GLE1 isoform X1 [KO:K18723]
114397682  DEAD-box ATP-dependent RNA helicase 38-like [KO:K18655] [EC:5.6.2.7]
114400165  DEAD-box ATP-dependent RNA helicase 38-like isoform X1 [KO:K18655] [EC:5.6.2.7]
114422204  protein RAE1-like [KO:K14298]
114412583  protein RAE1-like [KO:K14298]
114387960  protein RAE1-like [KO:K14298]
114387984  protein RAE1 [KO:K14298]
114377365  nuclear pore complex protein NUP98A-like [KO:K14297]
114378229  nuclear pore complex protein NUP98A-like [KO:K14297]
114384269  nuclear pore complex protein NUP96 [KO:K14297]
114416850  nuclear pore complex protein NUP214-like [KO:K14317]
114394444  nuclear pore complex protein NUP214-like [KO:K14317]
114382518  nuclear pore complex protein NUP88-like [KO:K14318]
114403211  RAN GTPase-activating protein 2-like [KO:K14319]
114372228  RAN GTPase-activating protein 1-like [KO:K14319]
114390105  RAN GTPase-activating protein 1-like [KO:K14319]
114371888  RAN GTPase-activating protein 2-like [KO:K14319]
114412397  SUMO-conjugating enzyme SCE1-like [KO:K10577]
114421937  SUMO-conjugating enzyme SCE1 [KO:K10577]
114376926  SUMO-conjugating enzyme SCE1-like [KO:K10577]
114391884  SUMO-conjugating enzyme SCE1-like [KO:K10577]
114381915  nuclear pore complex protein NUP160-like isoform X1 [KO:K14303]
114392629  nuclear pore complex protein NUP85 [KO:K14304]
114423443  protein transport protein SEC13 homolog B-like [KO:K14004]
114423458  protein transport protein SEC13 homolog B-like [KO:K14004]
114396733  protein transport protein SEC13 homolog B [KO:K14004]
114396635  protein transport protein SEC13 homolog B-like [KO:K14004]
114418197  nuclear pore complex protein NUP107 [KO:K14301]
114403537  nuclear pore complex protein NUP133-like [KO:K14300]
114384200  nuclear pore complex protein NUP133-like [KO:K14300]
114425356  protein SEH1-like [KO:K14299]
114374077  protein SEH1-like [KO:K14299]
114392144  nuclear pore complex protein NUP43 [KO:K14305]
114394688  nuclear pore complex protein NUP43-like [KO:K14305]
114412929  nuclear pore complex protein NUP62-like [KO:K14306]
114375873  nuclear pore complex protein NUP62-like [KO:K14306]
114421282  nuclear pore complex protein NUP58-like [KO:K14307]
114377148  nuclear pore complex protein NUP58-like [KO:K14307]
114381314  nuclear pore complex protein NUP54-like [KO:K14308]
114394870  nuclear pore complex protein NUP54 [KO:K14308]
114416744  nuclear pore complex protein NUP205 [KO:K14310]
114379619  nucleoporin NUP188 homolog [KO:K14311]
114413665  nuclear pore complex protein NUP155-like [KO:K14312]
114421220  nuclear pore complex protein NUP155-like [KO:K14312]
114388087  nuclear pore complex protein NUP93A-like [KO:K14309]
114376191  nuclear pore complex protein NUP93A-like [KO:K14309]
114377253  nuclear pore complex protein NUP35-like [KO:K14313]
114385761  nuclear pore complex protein NUP35-like [KO:K14313]
114377243  uncharacterized protein LOC114377243 isoform X1 [KO:K14315]
114385733  uncharacterized protein LOC114385733 [KO:K14315]
114411646  nuclear pore complex protein GP210 [KO:K14314]
114400845  uncharacterized protein LOC114400845 [KO:K20724]
114382736  uncharacterized protein LOC114382736 isoform X1 [KO:K20724]
114422051  nuclear-pore anchor-like isoform X1 [KO:K09291]
114387666  nuclear-pore anchor-like [KO:K09291]
114424355  uncharacterized protein LOC114424355 isoform X1 [KO:K14295]
114373936  uncharacterized protein LOC114373936 [KO:K14295]
114394674  importin subunit alpha-4-like [KO:K15042]
114394676  importin subunit alpha-4-like [KO:K15042]
114387959  importin subunit alpha-2 [KO:K15042]
114370905  importin subunit alpha-2-like [KO:K15042]
114393867  importin subunit alpha-2-like [KO:K15042]
114419993  importin subunit alpha-2-like [KO:K15042]
114398895  importin subunit alpha-4-like [KO:K15042]
114400211  importin subunit alpha-2-like [KO:K15042]
114407558  importin subunit alpha-2-like [KO:K15042]
114405329  importin subunit alpha-4-like [KO:K15042]
114403121  importin subunit alpha-2-like [KO:K15042]
114398281  importin subunit alpha-4-like isoform X1 [KO:K15042]
114396989  importin subunit alpha-1a-like [KO:K15042]
114367661  importin subunit alpha-2-like [KO:K15042]
114382729  importin subunit alpha-9 [KO:K15042]
114415572  importin subunit beta-1-like [KO:K14293]
114421094  importin subunit beta-1-like [KO:K14293]
114410276  importin subunit beta-1-like [KO:K14293]
114413478  importin subunit beta-1-like [KO:K14293]
114401529  transportin-1-like [KO:K18752]
114370346  transportin-1-like [KO:K18752]
114392345  transportin MOS14-like [KO:K15436]
114398109  transportin MOS14-like isoform X1 [KO:K15436]
114411909  transportin MOS14-like [KO:K15436]
114390203  transportin MOS14-like [KO:K15436]
114387862  importin-4-like [KO:K20221]
114422258  importin-4-like [KO:K20221]
114382313  uncharacterized protein LOC114382313 [KO:K20222]
114412922  importin-5-like [KO:K20222]
114421703  importin-5-like [KO:K20222]
114399345  importin-5-like [KO:K20222]
114389435  importin-5-like [KO:K20222]
114395406  importin beta-like SAD2 [KO:K20223]
114422826  importin beta-like SAD2 [KO:K20223]
114370512  importin beta-like SAD2 [KO:K20223]
114414385  importin-9-like [KO:K20224]
114388315  importin-9-like [KO:K20224]
114395823  importin-11-like isoform X1 [KO:K25201]
114419091  importin-11-like isoform X1 [KO:K25201]
114416208  snurportin-1 [KO:K13151]
114409942  snurportin-1-like isoform X1 [KO:K13151]
114376017  protein EXPORTIN 1A-like [KO:K14290]
114425833  protein EXPORTIN 1A-like [KO:K14290]
114375522  protein EXPORTIN 1A-like [KO:K14290]
114379282  protein EXPORTIN 1A isoform X1 [KO:K14290]
114418302  exportin-2-like [KO:K18423]
114389367  exportin-2 [KO:K18423]
114400204  exportin-T-like [KO:K14288]
114407871  exportin-T-like isoform X1 [KO:K14288]
114407740  exportin-4-like [KO:K25203]
114399442  exportin-4-like [KO:K25203]
114400309  protein HASTY 1-like [KO:K14289]
114407663  protein HASTY 1-like [KO:K14289]
114370133  exportin-7-A-like isoform X1 [KO:K18460]
114414414  exportin-7-B-like isoform X1 [KO:K18460]
114408388  exportin-7-B-like isoform X1 [KO:K18460]
114411709  GTP-binding nuclear protein Ran-1-like [KO:K07936]
114415003  GTP-binding nuclear protein Ran-3-like [KO:K07936]
114415004  GTP-binding nuclear protein Ran-3 [KO:K07936]
114415005  GTP-binding nuclear protein Ran-3-like [KO:K07936]
114408988  GTP-binding nuclear protein Ran-3-like [KO:K07936]
114408989  GTP-binding nuclear protein Ran-3-like [KO:K07936]
114408990  GTP-binding nuclear protein Ran-3-like [KO:K07936]
114412548  elongation factor 1-alpha-like [KO:K03231]
114400678  elongation factor 1-alpha [KO:K03231]
114412347  elongation factor 1-alpha-like [KO:K03231]
114393354  elongation factor 1-alpha [KO:K03231]
114370013  elongation factor 1-alpha-like isoform X1 [KO:K03231]
114390599  elongation factor 1-alpha-like [KO:K03231]
114414806  uncharacterized protein LOC114414806 [KO:K14291]
114408806  uncharacterized protein LOC114408806 [KO:K14291]
114383324  uncharacterized protein LOC114383324 [KO:K14291]
114400354  nuclear cap-binding protein subunit 1-like [KO:K12882]
114390309  nuclear cap-binding protein subunit 1-like [KO:K12882]
114379214  nuclear cap-binding protein subunit 2-like [KO:K12883]
114374773  nuclear cap-binding protein subunit 2-like [KO:K12883]
114396760  60S ribosomal export protein NMD3-like [KO:K07562]
114382314  60S ribosomal export protein NMD3-like [KO:K07562]
114425643  RNA-binding protein Y14-like [KO:K12876]
114377433  RNA-binding protein Y14-like [KO:K12876]
114373282  RNA-binding protein Y14-like [KO:K12876]
114418780  protein mago nashi homolog [KO:K12877]
114406496  protein mago nashi homolog [KO:K12877]
114386553  protein mago nashi homolog 2-like [KO:K12877]
114388065  eukaryotic initiation factor 4A-3 [KO:K13025] [EC:5.6.2.7]
114367890  eukaryotic initiation factor 4A-3-like [KO:K13025] [EC:5.6.2.7]
114397730  apoptotic chromatin condensation inducer in the nucleus-like [KO:K12875]
114382681  apoptotic chromatin condensation inducer in the nucleus-like isoform X1 [KO:K12875]
114405823  histone deacetylase complex subunit SAP18 [KO:K14324]
114402160  histone deacetylase complex subunit SAP18-like [KO:K14324]
114422117  serine/arginine-rich splicing factor SR45-like [KO:K14325]
114388512  serine/arginine-rich splicing factor SR45 [KO:K14325]
114422229  pinin-like [KO:K13114]
114388318  pinin-like [KO:K13114]
114395541  THO complex subunit 4D-like [KO:K12881]
114382087  THO complex subunit 4D-like [KO:K12881]
114377648  THO complex subunit 4A-like [KO:K12881]
114380373  THO complex subunit 4A-like [KO:K12881]
114385300  THO complex subunit 4B-like isoform X1 [KO:K12881]
114368491  THO complex subunit 4A-like [KO:K12881]
114376061  THO complex subunit 4A-like [KO:K12881]
114386340  regulator of nonsense transcripts UPF2-like [KO:K14327]
114367817  regulator of nonsense transcripts UPF2-like [KO:K14327]
114410497  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
114417479  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
114379752  regulator of nonsense transcripts UPF3-like [KO:K14328]
114390471  regulator of nonsense transcripts UPF3-like [KO:K14328]
114418110  DEAD-box ATP-dependent RNA helicase 56-like [KO:K12812] [EC:5.6.2.7]
114414990  DEAD-box ATP-dependent RNA helicase 56 [KO:K12812] [EC:5.6.2.7]
114422449  DEAD-box ATP-dependent RNA helicase 56-like [KO:K12812] [EC:5.6.2.7]
114408972  DEAD-box ATP-dependent RNA helicase 56-like [KO:K12812] [EC:5.6.2.7]
114374905  serine/arginine repetitive matrix protein 1-like [KO:K13171]
114380527  serine/arginine repetitive matrix protein 1-like [KO:K13171]
114422947  partner of Y14 and mago-like [KO:K14294]
114413040  partner of Y14 and mago-like [KO:K14294]
114409476  THO complex subunit 1 [KO:K12878]
114421238  THO complex subunit 2-like isoform X1 [KO:K12879]
114413686  THO complex subunit 2-like isoform X1 [KO:K12879]
114414724  THO complex subunit 5A-like isoform X1 [KO:K13174]
114408707  THO complex subunit 5A-like isoform X1 [KO:K13174]
114393934  THO complex subunit 5B-like [KO:K13174]
114385315  THO complex subunit 5B-like isoform X1 [KO:K13174]
114373550  THO complex subunit 7A-like [KO:K13176]
114388695  THO complex subunit 7A-like [KO:K13176]
114423590  THO complex subunit 3 [KO:K12880]
114396798  THO complex subunit 3-like [KO:K12880]
Reference
PMID:16777596
  Authors
Tran EJ, Wente SR
  Title
Dynamic nuclear pore complexes: life on the edge.
  Journal
Cell 125:1041-53 (2006)
DOI:10.1016/j.cell.2006.05.027
Reference
PMID:15519698
  Authors
Rodriguez MS, Dargemont C, Stutz F
  Title
Nuclear export of RNA.
  Journal
Biol Cell 96:639-55 (2004)
DOI:10.1016/j.biolcel.2004.04.014
Reference
PMID:18313922
  Authors
Palancade B, Doye V
  Title
Sumoylating and desumoylating enzymes at nuclear pores: underpinning their unexpected duties?
  Journal
Trends Cell Biol 18:174-83 (2008)
DOI:10.1016/j.tcb.2008.02.001
Reference
PMID:15901496
  Authors
Reed R, Cheng H
  Title
TREX, SR proteins and export of mRNA.
  Journal
Curr Opin Cell Biol 17:269-73 (2005)
DOI:10.1016/j.ceb.2005.04.011
Reference
PMID:16314458
  Authors
Tange TO, Shibuya T, Jurica MS, Moore MJ
  Title
Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
  Journal
RNA 11:1869-83 (2005)
DOI:10.1261/rna.2155905
Reference
PMID:28673770
  Authors
Beck M, Schirmacher P, Singer S
  Title
Alterations of the nuclear transport system in hepatocellular carcinoma - New basis for therapeutic strategies.
  Journal
J Hepatol 67:1051-1061 (2017)
DOI:10.1016/j.jhep.2017.06.021
Related
pathway
gsj03015  mRNA surveillance pathway
KO pathway
ko03013   
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