KEGG   PATHWAY: pvir04146
Entry
pvir04146                   Pathway                                
Name
Peroxisome - Panicum virgatum (switchgrass)
Description
Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
Class
Cellular Processes; Transport and catabolism
Pathway map
pvir04146  Peroxisome
pvir04146

Other DBs
GO: 0005777
Organism
Panicum virgatum (switchgrass) [GN:pvir]
Gene
120645491  peroxisome biogenesis protein 16-like [KO:K13335]
120706676  peroxisome biogenesis protein 16-like [KO:K13335]
120654499  peroxisome biogenesis protein 16-like isoform X1 [KO:K13335]
120660322  peroxisome biogenesis protein 3-2-like [KO:K13336]
120675522  peroxisome biogenesis protein 3-2-like [KO:K13336]
120656702  peroxisome biogenesis protein 19-1-like isoform X1 [KO:K13337]
120711660  peroxisome biogenesis protein 19-1-like isoform X1 [KO:K13337]
120678315  peroxisome biogenesis protein 1-like [KO:K13338]
120679603  peroxisome biogenesis protein 1-like isoform X1 [KO:K13338]
120713820  peroxisome biogenesis protein 1-like [KO:K13338]
120641790  peroxisome biogenesis protein 6-like isoform X1 [KO:K13339]
120641791  peroxisome biogenesis protein 6-like [KO:K13339]
120680847  peroxisome biogenesis protein 6-like isoform X1 [KO:K13339]
120655241  peroxisome biogenesis protein 7-like [KO:K13341]
120695717  peroxisome biogenesis protein 7-like [KO:K13341]
120678382  peroxisome biogenesis protein 5-like isoform X1 [KO:K13342]
120700392  peroxisomal membrane protein PEX14-like isoform X1 [KO:K13343]
120674040  peroxisomal membrane protein PEX14-like isoform X1 [KO:K13343]
120664375  peroxisomal membrane protein PEX14-like isoform X1 [KO:K13343]
120687892  peroxisomal membrane protein 13-like [KO:K13344]
120659346  peroxisomal membrane protein 13-like [KO:K13344]
120661991  peroxisomal membrane protein 13-like isoform X1 [KO:K13344]
120649531  peroxisomal membrane protein 13-like [KO:K13344]
120690256  peroxisome biogenesis protein 12-like isoform X1 [KO:K13345]
120650830  peroxisome biogenesis protein 12 [KO:K13345]
120658564  peroxisome biogenesis factor 10-like [KO:K13346]
120658602  stress-response A/B barrel domain-containing protein UP3-like [KO:K13346]
120694458  stress-response A/B barrel domain-containing protein UP3-like [KO:K13346]
120678565  peroxisome biogenesis protein 2-like [KO:K06664]
120665942  peroxisome biogenesis protein 2-like [KO:K06664]
120655145  peroxisomal membrane protein PMP22-like [KO:K13347]
120685259  protein sym-1-like [KO:K13347]
120646068  protein sym-1-like [KO:K13347]
120661348  protein sym-1-like [KO:K13347]
120712559  peroxisomal membrane protein PMP22 [KO:K13347]
120699587  PXMP2/4 family protein 4-like [KO:K13348]
120672812  protein Mpv17-like [KO:K13348]
120672824  mpv17-like protein [KO:K13348]
120688526  uncharacterized protein LOC120688526 [KO:K13348]
120673910  uncharacterized protein LOC120673910 isoform X1 [KO:K13348]
120705511  protein Mpv17 isoform X1 [KO:K13348]
120707929  protein Mpv17-like [KO:K13348]
120650464  uncharacterized protein LOC120650464 [KO:K13348]
120666299  PXMP2/4 family protein 4-like [KO:K13348]
120666605  uncharacterized protein LOC120666605 isoform X1 [KO:K13348]
120688574  peroxisomal nicotinamide adenine dinucleotide carrier-like [KO:K13354]
120646800  peroxisomal nicotinamide adenine dinucleotide carrier-like [KO:K13354]
120693208  peroxisomal nicotinamide adenine dinucleotide carrier-like isoform X1 [KO:K13354]
120652914  peroxisomal nicotinamide adenine dinucleotide carrier-like [KO:K13354]
120672655  2-hydroxyacyl-CoA lyase [KO:K12261] [EC:4.1.2.63]
120705520  2-hydroxyacyl-CoA lyase-like [KO:K12261] [EC:4.1.2.63]
120690913  phytanoyl-CoA dioxygenase 1-like [KO:K00477] [EC:1.14.11.18]
120650038  phytanoyl-CoA dioxygenase 1-like [KO:K00477] [EC:1.14.11.18]
120650040  phytanoyl-CoA dioxygenase 1-like [KO:K00477] [EC:1.14.11.18]
120654008  phytanoyl-CoA dioxygenase 2-like [KO:K00477] [EC:1.14.11.18]
120698518  phytanoyl-CoA dioxygenase 1-like isoform X1 [KO:K00477] [EC:1.14.11.18]
120669843  peroxisomal acyl-coenzyme A oxidase 1-like isoform X1 [KO:K00232] [EC:1.3.3.6]
120702698  peroxisomal acyl-coenzyme A oxidase 1-like [KO:K00232] [EC:1.3.3.6]
120703671  acyl-coenzyme A oxidase 3, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120703685  acyl-coenzyme A oxidase 3, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120704807  acyl-coenzyme A oxidase 4, peroxisomal-like isoform X1 [KO:K00232] [EC:1.3.3.6]
120705913  acyl-coenzyme A oxidase 4, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120675654  acyl-coenzyme A oxidase 4, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120697535  acyl-coenzyme A oxidase 4, peroxisomal-like isoform X1 [KO:K00232] [EC:1.3.3.6]
120667303  acyl-coenzyme A oxidase 4, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120667306  acyl-coenzyme A oxidase 4, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120684567  acyl-coenzyme A oxidase 2, peroxisomal-like [KO:K00232] [EC:1.3.3.6]
120657619  3-ketoacyl-CoA thiolase 2, peroxisomal-like [KO:K07513] [EC:2.3.1.16]
120646600  3-ketoacyl-CoA thiolase 2, peroxisomal-like [KO:K07513] [EC:2.3.1.16]
120691124  3-ketoacyl-CoA thiolase 2, peroxisomal-like [KO:K07513] [EC:2.3.1.16]
120650871  3-ketoacyl-CoA thiolase 2, peroxisomal-like [KO:K07513] [EC:2.3.1.16]
120641762  peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]-like [KO:K13237] [EC:1.3.1.124]
120641763  peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]-like [KO:K13237] [EC:1.3.1.124]
120682056  peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]-like isoform X1 [KO:K13237] [EC:1.3.1.124]
120682057  peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]-like [KO:K13237] [EC:1.3.1.124]
120709121  delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal-like [KO:K12663] [EC:5.3.3.21]
120709123  delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal-like [KO:K12663] [EC:5.3.3.21]
120672413  ABC transporter D family member 1-like [KO:K25819] [EC:7.6.2.4]
120709346  ABC transporter D family member 1-like [KO:K25819] [EC:7.6.2.4]
120697164  ABC transporter D family member 1-like isoform X1 [KO:K25819] [EC:7.6.2.4]
120667118  ABC transporter D family member 1-like isoform X1 [KO:K25819] [EC:7.6.2.4]
120686579  ABC transporter D family member 1-like isoform X1 [KO:K25819] [EC:7.6.2.4]
120658266  ABC transporter D family member 1-like [KO:K25819] [EC:7.6.2.4]
120685775  long chain acyl-CoA synthetase 2-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120686031  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
120686553  long chain acyl-CoA synthetase 6, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
120687465  probable acyl-activating enzyme 16, chloroplastic isoform X1 [KO:K01897] [EC:6.2.1.3]
120702677  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
120672425  long chain acyl-CoA synthetase 4-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120643541  long chain acyl-CoA synthetase 6, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
120643716  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
120643734  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
120673387  long chain acyl-CoA synthetase 8-like [KO:K01897] [EC:6.2.1.3]
120644688  long chain acyl-CoA synthetase 2-like [KO:K01897] [EC:6.2.1.3]
120660126  long chain acyl-CoA synthetase 8-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120675264  long chain acyl-CoA synthetase 4-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120707622  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
120649120  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
120663548  long chain acyl-CoA synthetase 6, peroxisomal-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120663695  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
120664160  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
120710034  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
120696687  long chain acyl-CoA synthetase 6, peroxisomal-like isoform X1 [KO:K01897] [EC:6.2.1.3]
120696816  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
120697358  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
120669597  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
120670671  nudix hydrolase 19, chloroplastic-like [KO:K03426] [EC:3.6.1.22]
120702555  nudix hydrolase 19, chloroplastic-like [KO:K03426] [EC:3.6.1.22]
120660589  malonyl-CoA decarboxylase, mitochondrial-like isoform X1 [KO:K01578] [EC:4.1.1.9]
120678835  malonyl-CoA decarboxylase, mitochondrial-like isoform X1 [KO:K01578] [EC:4.1.1.9]
120671250  probable fatty acyl-CoA reductase 4 [KO:K13356] [EC:1.2.1.84]
120658335  alcohol-forming fatty acyl-CoA reductase-like [KO:K13356] [EC:1.2.1.84]
120688607  fatty acyl-CoA reductase 2, chloroplastic-like [KO:K13356] [EC:1.2.1.84]
120659997  fatty acyl-CoA reductase 1-like [KO:K13356] [EC:1.2.1.84]
120647189  fatty acyl-CoA reductase 2, chloroplastic-like [KO:K13356] [EC:1.2.1.84]
120678999  fatty acyl-CoA reductase 1-like [KO:K13356] [EC:1.2.1.84]
120679708  fatty acyl-CoA reductase 1-like [KO:K13356] [EC:1.2.1.84]
120682192  fatty acyl-CoA reductase 1-like isoform X1 [KO:K13356] [EC:1.2.1.84]
120713082  fatty acyl-CoA reductase 1-like [KO:K13356] [EC:1.2.1.84]
120713083  fatty acyl-CoA reductase 1-like [KO:K13356] [EC:1.2.1.84]
120673356  mevalonate kinase-like [KO:K00869] [EC:2.7.1.36]
120706983  mevalonate kinase-like isoform X1 [KO:K00869] [EC:2.7.1.36]
120665799  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
120699049  serine--glyoxylate aminotransferase-like [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
120642438  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120672888  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120664571  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
120710029  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120681318  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120681850  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120697781  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120661131  probable sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
120706745  probable sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
120676633  probable sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
120695742  probable sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
120710571  probable sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
120685503  hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [KO:K01640] [EC:4.1.3.4]
120643495  hydroxymethylglutaryl-CoA lyase, mitochondrial-like [KO:K01640] [EC:4.1.3.4]
120673945  hydroxymethylglutaryl-CoA lyase, mitochondrial-like [KO:K01640] [EC:4.1.3.4]
120706487  hydroxymethylglutaryl-CoA lyase, mitochondrial-like [KO:K01640] [EC:4.1.3.4]
120663498  hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [KO:K01640] [EC:4.1.3.4]
120696643  hydroxymethylglutaryl-CoA lyase, mitochondrial-like [KO:K01640] [EC:4.1.3.4]
120641829  peroxisomal (S)-2-hydroxy-acid oxidase GLO3-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120641832  peroxisomal (S)-2-hydroxy-acid oxidase GLO2-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120641833  peroxisomal (S)-2-hydroxy-acid oxidase GLO2-like [KO:K11517] [EC:1.1.3.15]
120687891  peroxisomal (S)-2-hydroxy-acid oxidase GLO1-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120659345  peroxisomal (S)-2-hydroxy-acid oxidase GLO5-like [KO:K11517] [EC:1.1.3.15]
120661833  peroxisomal (S)-2-hydroxy-acid oxidase GLO4 isoform X1 [KO:K11517] [EC:1.1.3.15]
120661978  peroxisomal (S)-2-hydroxy-acid oxidase GLO5 [KO:K11517] [EC:1.1.3.15]
120649530  peroxisomal (S)-2-hydroxy-acid oxidase GLO1 [KO:K11517] [EC:1.1.3.15]
120694486  peroxisomal (S)-2-hydroxy-acid oxidase GLO4-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120682637  peroxisomal (S)-2-hydroxy-acid oxidase GLO3-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120683864  peroxisomal (S)-2-hydroxy-acid oxidase GLO3 [KO:K11517] [EC:1.1.3.15]
120684053  peroxisomal (S)-2-hydroxy-acid oxidase GLO2-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120689712  catalase isozyme C [KO:K03781] [EC:1.11.1.6]
120704548  catalase isozyme B [KO:K03781] [EC:1.11.1.6]
120647421  catalase isozyme C-like [KO:K03781] [EC:1.11.1.6]
120697493  catalase isozyme 3-like [KO:K03781] [EC:1.11.1.6]
120654421  catalase isozyme 3 [KO:K03781] [EC:1.11.1.6]
120668897  catalase isozyme B-like [KO:K03781] [EC:1.11.1.6]
120689703  superoxide dismutase [Cu-Zn] 4A-like [KO:K04565] [EC:1.15.1.1]
120691064  superoxide dismutase [Cu-Zn] 2-like isoform X1 [KO:K04565] [EC:1.15.1.1]
120646835  superoxide dismutase [Cu-Zn] 2-like isoform X1 [KO:K04565] [EC:1.15.1.1]
120662108  superoxide dismutase [Cu-Zn] 2-like isoform X1 [KO:K04565] [EC:1.15.1.1]
120679092  superoxide dismutase [Cu-Zn], chloroplastic [KO:K04565] [EC:1.15.1.1]
120694780  superoxide dismutase [Cu-Zn] 2 [KO:K04565] [EC:1.15.1.1]
120652356  superoxide dismutase [Cu-Zn] 4A [KO:K04565] [EC:1.15.1.1]
120713114  superoxide dismutase [Cu-Zn], chloroplastic-like isoform X1 [KO:K04565] [EC:1.15.1.1]
120669918  superoxide dismutase [Fe] 1, chloroplastic-like [KO:K04564] [EC:1.15.1.1]
120702403  superoxide dismutase [Fe] 1, chloroplastic-like [KO:K04564] [EC:1.15.1.1]
120679332  superoxide dismutase [Fe] 2, chloroplastic-like [KO:K04564] [EC:1.15.1.1]
120665901  superoxide dismutase [Mn] 3.4, mitochondrial isoform X1 [KO:K04564] [EC:1.15.1.1]
120712869  superoxide dismutase [Fe] 2, chloroplastic-like isoform X1 [KO:K04564] [EC:1.15.1.1]
120699121  superoxide dismutase [Mn] 3.4, mitochondrial-like [KO:K04564] [EC:1.15.1.1]
120690993  xanthine dehydrogenase-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
120699319  tropinone reductase-like 3 [KO:K11147] [EC:1.1.-.-]
120666065  tropinone reductase-like 3 [KO:K11147] [EC:1.1.-.-]
Reference
PMID:17055078
  Authors
Wanders RJ, Waterham HR
  Title
Peroxisomal disorders: the single peroxisomal enzyme deficiencies.
  Journal
Biochim Biophys Acta 1763:1707-20 (2006)
DOI:10.1016/j.bbamcr.2006.08.010
Reference
PMID:17055079
  Authors
Steinberg SJ, Dodt G, Raymond GV, Braverman NE, Moser AB, Moser HW
  Title
Peroxisome biogenesis disorders.
  Journal
Biochim Biophys Acta 1763:1733-48 (2006)
DOI:10.1016/j.bbamcr.2006.09.010
Reference
PMID:17010456
  Authors
Rottensteiner H, Theodoulou FL
  Title
The ins and outs of peroxisomes: co-ordination of membrane transport and peroxisomal metabolism.
  Journal
Biochim Biophys Acta 1763:1527-40 (2006)
DOI:10.1016/j.bbamcr.2006.08.012
Reference
PMID:16631601
  Authors
Iida R, Yasuda T, Tsubota E, Takatsuka H, Matsuki T, Kishi K
  Title
Human Mpv17-like protein is localized in peroxisomes and regulates expression of antioxidant enzymes.
  Journal
Biochem Biophys Res Commun 344:948-54 (2006)
DOI:10.1016/j.bbrc.2006.04.008
Related
pathway
pvir00071  Fatty acid degradation
pvir00230  Purine metabolism
pvir00564  Glycerophospholipid metabolism
pvir00565  Ether lipid metabolism
pvir00900  Terpenoid backbone biosynthesis
KO pathway
ko04146   
LinkDB

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