KEGG   PATHWAY: pmav04820
Entry
pmav04820                   Pathway                                
Name
Cytoskeleton in muscle cells - Peromyscus maniculatus bairdii (prairie deer mouse)
Class
Cellular Processes; Cell motility
Pathway map
pmav04820  Cytoskeleton in muscle cells
pmav04820

Organism
Peromyscus maniculatus bairdii (prairie deer mouse) [GN:pmav]
Gene
102902782  Lmna; lamin isoform X1 [KO:K12641]
102902808  Ampd1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
102902904  Ampd2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
102903090  Sdc2; syndecan-2 isoform X1 [KO:K16336]
102903187  Zyx; zyxin isoform X1 [KO:K06273]
102903779  Col9a2; collagen alpha-2(IX) chain isoform X1 [KO:K08131]
102903867  Mypn; myopalladin isoform X1 [KO:K22028]
102903976  Myom1; myomesin-1 isoform X2 [KO:K24495]
102904313  Myom2; myomesin-2 [KO:K24495]
102904316  Trim55; tripartite motif-containing protein 55 isoform X1 [KO:K10654]
102904591  Atp1a2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
102905010  Col6a1; collagen alpha-1(VI) chain [KO:K06238]
102905089  Atp1a4; sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
102905106  Itga6; integrin alpha-6 isoform X2 [KO:K06485]
102905299  Myh14; myosin-14 isoform X3 [KO:K10352]
102905328  Col6a2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
102905486  Fbln1; fibulin-1 isoform X1 [KO:K17307]
102905522  Itgb3; integrin beta-3 [KO:K06493]
102905830  Myl4; myosin light chain 4 [KO:K12750]
102905887  Capn3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
102906559  Pdlim3; PDZ and LIM domain protein 3 isoform X1 [KO:K23353]
102906845  Pdlim2; PDZ and LIM domain protein 2 isoform X2 [KO:K23353]
102907170  Sun1; SUN domain-containing protein 1 isoform X3 [KO:K19347]
102907397  Fmn2; formin-2 [KO:K02184]
102907445  Sptan1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
102907449  Mybpc3; myosin-binding protein C, cardiac-type [KO:K12568]
102907500  Eno3; beta-enolase isoform X1 [KO:K01689] [EC:4.2.1.11]
102907626  Syne3; nesprin-3 isoform X2 [KO:K21761]
102907670  Myl9; myosin regulatory light polypeptide 9 [KO:K12755]
102907808  Col3a1; collagen alpha-1(III) chain [KO:K19720]
102907890  Bgn; biglycan [KO:K08118]
102907898  Myh10; myosin-10 isoform X1 [KO:K10352]
102908104  Col5a2; collagen alpha-2(V) chain isoform X1 [KO:K19721]
102908341  Fhl3; four and a half LIM domains protein 3 [KO:K24414]
102908355  Itgb6; integrin beta-6 isoform X1 [KO:K06589]
102908690  Plec; plectin isoform X2 [KO:K10388]
102908880  Tnnc1; troponin C, slow skeletal and cardiac muscles [KO:K05865]
102909036  Itgb4; integrin beta-4 isoform X2 [KO:K06525]
102909144  Sgcz; zeta-sarcoglycan [KO:K27062]
102909425  Col4a3; collagen alpha-3(IV) chain [KO:K06237]
102909666  Csrp2; cysteine and glycine-rich protein 2 [KO:K09377]
102909714  Itga10; integrin alpha-10 isoform X1 [KO:K06586]
102909746  Col4a4; collagen alpha-4(IV) chain isoform X2 [KO:K06237]
102909993  Diaph3; protein diaphanous homolog 3 isoform X1 [KO:K05745]
102910268  Fhl2; four and a half LIM domains protein 2 isoform X1 [KO:K14380]
102910410  Tcap; telethonin [KO:K19879]
102910546  C9H10orf71; cardiac-enriched FHL2-interacting protein [KO:K28413]
102910683  Actc1; actin, alpha cardiac muscle 1 [KO:K12314]
102910688  Myoz3; myozenin-3 [KO:K26050]
102910876  Capzb; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
102910944  Col6a5; collagen alpha-5(VI) chain [KO:K06238]
102911025  Tpm4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
102911222  Sgce; epsilon-sarcoglycan isoform X9 [KO:K27061]
102911248  Col6a6; collagen alpha-6(VI) chain [KO:K06238]
102911356  Actg2; actin, gamma-enteric smooth muscle [KO:K12315]
102911634  Col4a5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
102911716  Tnnt2; troponin T, cardiac muscle isoform X1 [KO:K12045]
102911717  Itgb1; integrin beta-1 isoform X1 [KO:K05719]
102911819  Sdc1; syndecan-1 isoform X1 [KO:K06257]
102911965  Col4a6; collagen alpha-6(IV) chain [KO:K06237]
102911968  Col1a2; collagen alpha-2(I) chain isoform X1 [KO:K06236]
102912189  Itga3; integrin alpha-3 isoform X1 [KO:K06482]
102912255  Mybpc1; myosin-binding protein C, slow-type isoform X5 [KO:K12557]
102912339  Capza3; F-actin-capping protein subunit alpha-3 isoform X5 [KO:K10364]
102912369  Tnni1; troponin I, slow skeletal muscle [KO:K10371]
102912549  Myl11; myosin regulatory light chain 11 [KO:K12758]
102912562  Nid2; nidogen-2 [KO:K06826]
102912634  [KO:K24220]
102912643  Itgb5; integrin beta-5 isoform X1 [KO:K06588]
102912724  Pkp2; plakophilin-2 [KO:K12642]
102912812  Dsg2; desmoglein-2 [KO:K07597]
102912909  Lama2; laminin subunit alpha-2 [KO:K05637]
102912943  Tmod2; tropomodulin-2 [KO:K10370]
102913012  Inf2; inverted formin-2 isoform X3 [KO:K23958]
102913032  Fbln2; fibulin-2 isoform X1 [KO:K17307]
102913146  Myh13; myosin-13 [KO:K24220]
102913161  Trim63; E3 ubiquitin-protein ligase TRIM63 [KO:K10655] [EC:2.3.2.27]
102913466  [KO:K24220]
102913570  Atp1b1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
102913606  Itga1; integrin alpha-1 [KO:K06480]
102913618  Csrp1; cysteine and glycine-rich protein 1 isoform X2 [KO:K09377]
102913633  Col5a3; collagen alpha-3(V) chain isoform X1 [KO:K19721]
102913671  Tmod3; tropomodulin-3 [KO:K10370]
102913838  Pdlim1; PDZ and LIM domain protein 1 [KO:K23353]
102913923  Itga2; integrin alpha-2 [KO:K06481]
102913972  Fmnl1; formin-like protein 1 isoform X4 [KO:K23957]
102913980  Sgca; alpha-sarcoglycan [KO:K12565]
102914264  Ank2; ankyrin-2 isoform X1 [KO:K09255]
102914275  Col1a1; collagen alpha-1(I) chain [KO:K06236]
102914287  [KO:K24220]
102914355  Sgcg; gamma-sarcoglycan isoform X2 [KO:K12564]
102914386  Myoz2; myozenin-2 [KO:K26050]
102914469  Sspn; sarcospan isoform X1 [KO:K22194]
102914500  Tmem43; transmembrane protein 43 [KO:K27488]
102914521  Itgav; integrin alpha-V isoform X1 [KO:K06487]
102914597  Myh1; myosin-1 [KO:K24220]
102914689  Synpo2; synaptopodin-2 isoform X1 [KO:K24066]
102914787  Itga11; integrin alpha-11 [KO:K06587]
102914855  Itgb7; integrin beta-7 [KO:K06590]
102914862  Myh11; myosin-11 isoform X1 [KO:K10352]
102914983  Comp; cartilage oligomeric matrix protein isoform X1 [KO:K04659]
102915174  Lmod1; leiomodin-1 [KO:K22030]
102915175  Tmod4; tropomodulin-4 [KO:K10370]
102915193  Atp1a3; sodium/potassium-transporting ATPase subunit alpha-3 isoform X2 [KO:K01539] [EC:7.2.2.13]
102915493  Capza1; F-actin-capping protein subunit alpha-1 [KO:K10364]
102915549  Col11a2; collagen alpha-2(XI) chain isoform X1 [KO:K19721]
102915929  Col9a1; collagen alpha-1(IX) chain [KO:K08131]
102916016  Myh7b; myosin-7B isoform X1 [KO:K24220]
102916289  Col9a3; collagen alpha-3(IX) chain [KO:K08131]
102916674  Agrn; agrin isoform X5 [KO:K06254]
102917488  Ankrd2; ankyrin repeat domain-containing protein 2 [KO:K21434]
102917563  Tpm2; tropomyosin beta chain isoform X2 [KO:K10374]
102917598  Xirp2; xin actin-binding repeat-containing protein 2 isoform X2 [KO:K27381]
102917647  Sptbn2; spectrin beta chain, non-erythrocytic 2 isoform X2 [KO:K23932]
102917798  Lmod2; leiomodin-2 [KO:K22030]
102917987  Ankrd1; ankyrin repeat domain-containing protein 1 [KO:K21433]
102918704  Tln1; talin-1 isoform X2 [KO:K06271]
102918870  Col11a1; collagen alpha-1(XI) chain [KO:K19721]
102918881  Nid1; nidogen-1 isoform X2 [KO:K06826]
102918900  Col24a1; collagen alpha-1(XXIV) chain [KO:K19721]
102918938  Dsp; desmoplakin isoform X1 [KO:K10381]
102918970  Tnni2; troponin I, fast skeletal muscle [KO:K12043]
102919166  Csrp3; cysteine and glycine-rich protein 3 isoform X1 [KO:K09377]
102919194  [KO:K05692]
102919256  Thbs3; thrombospondin-3 isoform X1 [KO:K04659]
102919398  Actn3; alpha-actinin-3 [KO:K21073]
102919510  Diaph2; protein diaphanous homolog 2 isoform X1 [KO:K05741]
102919622  Atp1a1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
102919636  Tnnc2; troponin C, skeletal muscle [KO:K12042]
102919832  Myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
102919886  Snta1; alpha-1-syntrophin [KO:K24063]
102919977  Sptbn4; spectrin beta chain, non-erythrocytic 4 isoform X1 [KO:K06115]
102920013  Thbs4; thrombospondin-4 [KO:K04659]
102920131  Itga8; integrin alpha-8 isoform X1 [KO:K06584]
102920154  Sdc4; syndecan-4 [KO:K16338]
102920279  Jup; junction plakoglobin [KO:K10056]
102920524  Tln2; talin-2 isoform X2 [KO:K06271]
102920697  Thbs2; thrombospondin-2 [KO:K04659]
102920710  Lmnb2; lamin-B2 isoform X1 [KO:K07611]
102920809  Myot; myotilin isoform X1 [KO:K19875]
102920897  Fmnl2; formin-like protein 2 isoform X1 [KO:K23957]
102920922  Tnnt3; troponin T, fast skeletal muscle isoform X9 [KO:K12046]
102920941  Actn2; alpha-actinin-2 [KO:K21073]
102921157  Sntb1; beta-1-syntrophin [KO:K24064]
102921221  Myom3; myomesin-3 [KO:K24495]
102921258  Fbn2; fibrillin-2 [KO:K23342]
102921398  Ckm; creatine kinase M-type [KO:K27382]
102921581  Fhl1; four and a half LIM domains protein 1 isoform X3 [KO:K14365]
102921702  Atp1b2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
102921785  Actg1; actin, cytoplasmic 2 [KO:K05692]
102922102  Acta1; actin, alpha skeletal muscle [KO:K10354]
102922104  Itga2b; integrin alpha-IIb isoform X1 [KO:K06476]
102922400  Vim; vimentin [KO:K07606]
102922522  Col5a1; collagen alpha-1(V) chain isoform X1 [KO:K19721]
102922603  Sgcd; delta-sarcoglycan [KO:K12563]
102922682  Dag1; dystroglycan 1 [KO:K06265]
102922694  Sgcb; beta-sarcoglycan [KO:K12566]
102922805  Col6a3; collagen alpha-3(VI) chain isoform X4 [KO:K06238]
102923155  Neb; nebulin isoform X2 [KO:K18267]
102923190  Thbs1; thrombospondin-1 [KO:K16857]
102923204  Hspg2; basement membrane-specific heparan sulfate proteoglycan core protein isoform X4 [KO:K06255]
102923255  Eno2; gamma-enolase [KO:K01689] [EC:4.2.1.11]
102923511  Col27a1; collagen alpha-1(XXVII) chain isoform X1 [KO:K19721]
102923782  Tmod1; tropomodulin-1 isoform X1 [KO:K10370]
102923877  Emd; emerin isoform X1 [KO:K12569]
102923929  Flnc; filamin-C isoform X1 [KO:K27393]
102923961  Myh15; myosin-15 [KO:K24220]
102924023  Mybph; myosin-binding protein H isoform X2 [KO:K24494]
102924025  Lmnb1; lamin-B1 [KO:K07611]
102924337  Pdlim4; PDZ and LIM domain protein 4 isoform X3 [KO:K23353]
102924375  Capza2; F-actin-capping protein subunit alpha-2 [KO:K10364]
102924408  Trim54; tripartite motif-containing protein 54 [KO:K10653]
102924491  Myh9; myosin-9 [KO:K10352]
102924496  Fn1; fibronectin isoform X8 [KO:K05717]
102924640  Col4a2; collagen alpha-2(IV) chain [KO:K06237]
102924692  Lama1; laminin subunit alpha-1 [KO:K05637]
102924704  Lmod3; leiomodin-3 [KO:K22030]
102924835  Sdc3; syndecan-3 isoform X1 [KO:K16337]
102925176  Col4a1; collagen alpha-1(IV) chain [KO:K06237]
102925202  Dcn; decorin [KO:K04660]
102925384  Atp1b4; protein ATP1B4 [KO:K01540]
102925485  [KO:K07601]
102925676  Syne1; nesprin-1 isoform X4 [KO:K19326]
102925682  Sun2; SUN domain-containing protein 2 isoform X1 [KO:K19347]
102925722  Daam1; disheveled-associated activator of morphogenesis 1 isoform X2 [KO:K04512]
102925754  Syne2; nesprin-2 isoform X3 [KO:K19346]
102925760  Sntb2; beta-2-syntrophin isoform X1 [KO:K24064]
102925798  Itga5; integrin alpha-5 [KO:K06484]
102925992  Ampd3; AMP deaminase 3 isoform X3 [KO:K01490] [EC:3.5.4.6]
102926060  Des; desmin [KO:K07610]
102926086  Obscn; obscurin isoform X1 [KO:K17531] [EC:2.7.11.1]
102926207  Mybphl; myosin-binding protein H-like [KO:K24494]
102926584  Myl1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
102926680  Myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
102926746  Itga7; integrin alpha-7 isoform X2 [KO:K06583]
102926961  Eln; elastin [KO:K14211]
102927051  Itgb8; integrin beta-8 isoform X1 [KO:K06591]
102927136  Vcl; vinculin isoform X1 [KO:K05700]
102927145  Itga9; integrin alpha-9 isoform X2 [KO:K06585]
102927393  Tnnt1; troponin T, slow skeletal muscle isoform X1 [KO:K10372]
102927451  [KO:K17751]
102927578  Actb; actin, cytoplasmic 1 [KO:K05692]
102927717  Nrap; nebulin-related-anchoring protein isoform X2 [KO:K24421]
102927752  Myh6; myosin-6 isoform X1 [KO:K17751]
102927753  Lbr; delta(14)-sterol reductase LBR [KO:K19532] [EC:1.3.1.70]
102927883  Sptbn1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
102927887  Fbn1; fibrillin-1 isoform X1 [KO:K06825]
102927990  Daam2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
102927999  Myl3; myosin light chain 3 [KO:K12749]
102928096  Tnni3; troponin I, cardiac muscle isoform X2 [KO:K12044]
102928103  Ldb3; LIM domain-binding protein 3 isoform X5 [KO:K19867]
102928481  Fmnl3; formin-like protein 3 isoform X1 [KO:K23957]
102928663  Itga4; integrin alpha-4 [KO:K06483]
102929150  Mybpc2; myosin-binding protein C, fast-type isoform X2 [KO:K12558]
121826775  [KO:K24220]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
pmav04512  ECM-receptor interaction
pmav04814  Motor proteins
KO pathway
ko04820   

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