KEGG   PATHWAY: sluc04081
Entry
sluc04081                   Pathway                                
Name
Hormone signaling - Sander lucioperca (pikeperch)
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
sluc04081  Hormone signaling
sluc04081

Organism
Sander lucioperca (pikeperch) [GN:sluc]
Gene
116034047  calca; calcitonin/calcitonin-related polypeptide, alpha isoform X1 [KO:K12332]
116034132  [KO:K05256]
116034333  smad1; mothers against decapentaplegic homolog 1 [KO:K04676]
116034736  ghrb; growth hormone receptor b isoform X1 [KO:K05080]
116034786  [KO:K12324] [EC:4.6.1.2]
116034793  pmchl; pro-melanin-concentrating hormone, like [KO:K05229]
116034858  adra1ab; alpha-1A adrenergic receptor [KO:K04135]
116034923  jak2a; tyrosine-protein kinase JAK2a isoform X1 [KO:K04447] [EC:2.7.10.2]
116034940  drd5a; D(1B) dopamine receptor [KO:K05840]
116034988  smad4a; mothers against decapentaplegic homolog 4a [KO:K04501]
116035056  bmpr1bb; bone morphogenetic protein receptor, type IBb isoform X1 [KO:K13578] [EC:2.7.11.30]
116035061  [KO:K04314]
116035212  crhr1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
116035303  ccka; cholecystokinin a [KO:K05226]
116035336  [KO:K23106]
116035337  [KO:K23106]
116035338  [KO:K23106]
116035345  [KO:K23106]
116035346  [KO:K23106]
116035358  trhra; thyrotropin-releasing hormone receptor [KO:K04282]
116035363  [KO:K23106]
116035364  [KO:K23106]
116035392  [KO:K05257]
116035426  [KO:K04203]
116035428  mc2r; adrenocorticotropic hormone receptor [KO:K04200]
116035468  [KO:K04280]
116035514  thrb; thyroid hormone receptor beta isoform X1 [KO:K08362]
116035628  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X2 [KO:K05858] [EC:3.1.4.11]
116035667  cga; glycoprotein hormones alpha chain isoform X1 [KO:K08522]
116035687  si:dkey-222b8.1; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
116035809  prlh2r; prolactin releasing hormone 2 receptor [KO:K04314]
116035861  oprd1a; opioid receptor, delta 1a [KO:K04213]
116036286  drd4a; dopamine receptor D4a [KO:K04147]
116036467  si:dkey-178o16.4; oxytocin receptor [KO:K04228]
116036484  smad5; mothers against decapentaplegic homolog 5 [KO:K16790]
116036599  agtr2; type-2 angiotensin II receptor [KO:K04167]
116036769  dio2; type II iodothyronine deiodinase [KO:K17904] [EC:1.21.99.4]
116036816  esr2b; estrogen receptor 2b [KO:K08551]
116037077  [KO:K04142]
116037092  drd1b; dopamine receptor D1b [KO:K04144]
116037129  smad9; mothers against decapentaplegic homolog 9 [KO:K16791]
116037213  [KO:K04351]
116037223  ghrh; somatoliberin [KO:K05260]
116037246  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
116037249  stk11; serine/threonine-protein kinase STK11 isoform X1 [KO:K07298] [EC:2.7.11.1]
116037616  adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
116037627  gnb5b; guanine nucleotide-binding protein subunit beta-5b [KO:K04539]
116037646  [KO:K04280]
116037863  prlh2; prolactin releasing hormone 2 [KO:K05269]
116037878  crhb; corticotropin releasing hormone b [KO:K05256]
116037971  drd3; D(3) dopamine receptor isoform X1 [KO:K04146]
116038031  vipr1b; vasoactive intestinal polypeptide receptor 1b [KO:K04589]
116038100  [KO:K00922] [EC:2.7.1.153]
116038115  ghrhrb; pituitary adenylate cyclase-activating polypeptide type I receptor [KO:K04589]
116038182  [KO:K08041] [EC:4.6.1.1]
116038421  [KO:K04513]
116038464  igf2b; insulin-like growth factor 2b [KO:K13769]
116038514  gnb5a; guanine nucleotide-binding protein subunit beta-5a [KO:K04539]
116038578  [KO:K05439]
116038619  [KO:K22608]
116038669  [KO:K08747]
116038725  avpr1aa; arginine vasopressin receptor 1Aa [KO:K04226]
116038779  gnrhr4; gonadotropin releasing hormone receptor 4 [KO:K04280]
116038947  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
116039135  lepr; leptin receptor [KO:K05062]
116039141  nppal; natriuretic peptide A-like [KO:K12336]
116039183  nppa; natriuretic peptides A [KO:K12334]
116039196  mpl; thrombopoietin receptor [KO:K05082]
116039203  avpr2aa; vasopressin V2 receptor [KO:K04228]
116039341  [KO:K08046] [EC:4.6.1.1]
116039692  adra2c; alpha-2C adrenergic receptor [KO:K04140]
116039786  avpr2l; arginine vasopressin receptor 2, like [KO:K04228]
116039890  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
116039916  gipr; gastric inhibitory polypeptide receptor [KO:K04580]
116040029  [KO:K04590]
116040068  mc4r; melanocortin receptor 4 [KO:K04202]
116040244  trhr2; thyrotropin releasing hormone receptor 2 [KO:K04282]
116040320  slc16a10; monocarboxylate transporter 10 [KO:K08187]
116040592  [KO:K04144]
116040638  gnas; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632]
116040653  gnb1a; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
116040726  [KO:K18832]
116040854  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
116040886  gnai3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
116040928  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
116041211  adcy2b; adenylate cyclase type 2b isoform X1 [KO:K08042] [EC:4.6.1.1]
116041265  cckb; cholecystokinin [KO:K05226]
116041479  [KO:K04249]
116041528  [KO:K04630]
116041618  [KO:K04513]
116041700  ghrl; ghrelin/obestatin prepropeptide [KO:K05254]
116041735  oxtr; oxytocin receptor [KO:K04229]
116041737  [KO:K04228]
116041828  [KO:K04139]
116041939  [KO:K05858] [EC:3.1.4.11]
116041966  tshr; thyrotropin receptor [KO:K04249]
116042077  prl2; prolactin 2 [KO:K05439]
116042304  epoa; erythropoietin isoform X1 [KO:K05437]
116042587  si:ch211-286b5.5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04545]
116042660  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
116042778  mchr1a; melanin-concentrating hormone receptor 1 [KO:K04320]
116042792  adcy9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
116042805  gcgrb; glucagon receptor [KO:K04583]
116042812  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
116042866  [KO:K04219]
116042894  adra2a; alpha-2A adrenergic receptor [KO:K04138]
116042980  [KO:K05226]
116043067  [KO:K04221]
116043145  slc40a1; solute carrier family 40 member 1 [KO:K14685]
116043272  cckar; cholecystokinin receptor type A [KO:K04194]
116043388  fshb; gonadotropin subunit beta-1 [KO:K05251]
116043636  [KO:K04282]
116043666  src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
116043746  rapgef3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
116043858  sstr1b; somatostatin receptor type 1 [KO:K04217]
116043900  smtla; somatolactin alpha [KO:K05438]
116043983  vipr2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
116044348  [KO:K04246]
116044469  ramp1; receptor activity-modifying protein 1 isoform X1 [KO:K08447]
116044513  [KO:K05259]
116044568  irs2a; insulin receptor substrate 2a isoform X1 [KO:K07187]
116044583  si:dkey-1h24.2; cholecystokinin receptor isoform X1 [KO:K04194]
116044740  adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
116044757  [KO:K05228]
116044846  [KO:K05080]
116044861  [KO:K08447]
116045102  gna13b; guanine nucleotide-binding protein subunit alpha-13b [KO:K04639]
116045350  [KO:K04214]
116045678  igf1ra; insulin-like growth factor 1a receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
116045807  [KO:K02649]
116045912  insra; insulin receptor a [KO:K04527] [EC:2.7.10.1]
116045955  oprk1; kappa-type opioid receptor [KO:K04214]
116045964  pth1r; parathyroid hormone/parathyroid hormone-related peptide receptor [KO:K04585]
116046015  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b isoform X1 [KO:K04345] [EC:2.7.11.11]
116046040  [KO:K08041] [EC:4.6.1.1]
116046091  thpo; thrombopoietin isoform X1 [KO:K06854]
116046126  [KO:K00922] [EC:2.7.1.153]
116046225  [KO:K04579]
116046247  [KO:K04542]
116046249  [KO:K04589]
116046302  [KO:K08449]
116046416  gnb3b; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3b [KO:K07825]
116046502  gnao1a; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a isoform X1 [KO:K04534]
116046614  itgav; integrin alpha-V [KO:K06487]
116046773  epor; erythropoietin receptor [KO:K05079]
116046825  [KO:K12332]
116046847  irs2b; insulin receptor substrate 2 [KO:K07187]
116046897  [KO:K04194]
116046901  sstr2a; somatostatin receptor type 2 [KO:K04218]
116046909  [KO:K04218]
116046997  pnocb; prepronociceptin b [KO:K25696]
116047147  trhrb; thyrotropin-releasing hormone receptor b [KO:K04282]
116047629  [KO:K08447]
116047749  si:dkey-202l22.3; 7 transmembrane receptor domain-containing protein [KO:K04314]
116047825  pth4; parathyroid hormone 4 [KO:K22608]
116047909  [KO:K04226]
116047966  drd2a; dopamine receptor D2a [KO:K04145]
116048288  [KO:K08747]
116048428  rapgef4a; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
116048511  mlnr; growth hormone secretagogue receptor type 1 [KO:K05266]
116048739  si:ch73-139e5.4; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
116048784  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
116048982  si:ch73-335l21.1; insulin receptor substrate 1-B [KO:K16172]
116049034  [KO:K04140]
116049057  sst5; somatostatin-1A [KO:K05237]
116049201  adcy2a; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
116049286  oprd1b; opioid receptor, delta 1b [KO:K04213]
116049304  [KO:K04675] [EC:2.7.11.30]
116049381  si:ch211-254p10.2; solute carrier family 40 member 1 [KO:K14685]
116049699  wu:fj39g12; C-type natriuretic peptide 1 [KO:K12336]
116049728  gnb3a; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3a [KO:K07825]
116050373  [KO:K19477] [EC:2.7.11.12]
116050439  npr3; atrial natriuretic peptide receptor 3 [KO:K12325]
116050910  hcrtr2; orexin receptor type 2 [KO:K04239]
116051144  appl1; DCC-interacting protein 13-alpha [KO:K08733]
116051173  [KO:K04541]
116051206  [KO:K23106]
116051223  si:ch211-220m17.5; guanylin family protein [KO:K25556]
116051241  gnai2b; guanine nucleotide-binding protein G(i) subunit alpha-2b isoform X1 [KO:K04630]
116051270  gnb1b; guanine nucleotide binding protein (G protein), beta polypeptide 1b [KO:K04536]
116051389  [KO:K04632]
116051428  [KO:K05704] [EC:2.7.10.2]
116051439  rhoca; ras homolog family member Ca isoform X1 [KO:K04513]
116051490  [KO:K25556]
116051571  oxtrl; oxytocin receptor like [KO:K04229]
116051618  tshba; thyroid stimulating hormone subunit beta a [KO:K05251]
116052062  insb; preproinsulin b [KO:K04526]
116052070  adrb2a; adrenoceptor beta 2, surface a [KO:K04142]
116052122  lhcgr; lutropin-choriogonadotropic hormone receptor isoform X2 [KO:K04248]
116052234  adra1d; alpha-1D adrenergic receptor [KO:K04137]
116052385  slc16a2; monocarboxylate transporter 8 [KO:K08231]
116052925  [KO:K05547]
116052940  prl; prolactin [KO:K05439]
116053059  [KO:K02649]
116053173  [KO:K07187]
116053756  agtr1b; type-1 angiotensin II receptor [KO:K04166]
116053894  adrb3a; adrenoceptor beta 3a [KO:K04143]
116053915  prlhr2a; prolactin releasing hormone receptor 2a [KO:K04314]
116053970  oxt; oxytocin-neurophysin 1 isoform X1 [KO:K05243]
116053972  [KO:K05242]
116053979  adra2b; alpha-2B adrenergic receptor [KO:K04139]
116054059  jak2b; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
116054106  prkg2; cGMP-dependent protein kinase 2 isoform X1 [KO:K19477] [EC:2.7.11.12]
116054158  nos1; nitric oxide synthase, brain isoform X2 [KO:K13240] [EC:1.14.13.39]
116054165  adra1aa; adrenoceptor alpha 1Aa [KO:K04135]
116054378  ghra; growth hormone receptor a [KO:K05080]
116054582  [KO:K08747]
116054583  [KO:K08747]
116054584  [KO:K08039]
116055114  [KO:K04589]
116055147  [KO:K07376] [EC:2.7.11.12]
116055182  [KO:K12324] [EC:4.6.1.2]
116055274  insrb; insulin receptor b [KO:K04527] [EC:2.7.10.1]
116055283  [KO:K04538]
116055305  [KO:K04542]
116055353  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
116055356  [KO:K04138]
116055360  nppc; C-type natriuretic peptide [KO:K12336]
116055393  [KO:K04637]
116055441  [KO:K04635]
116055457  gnrh3; gonadotropin-releasing hormone 3 [KO:K05252]
116055549  sst1.1; somatostatin 1, tandem duplicate 1 [KO:K05237]
116055552  sst1.2; somatostatin 1.2 [KO:K05237]
116055658  [KO:K05228]
116055721  agt; angiotensinogen [KO:K09821]
116055914  [KO:K04136]
116056237  [KO:K04673] [EC:2.7.11.30]
116056253  oprm1; mu-type opioid receptor isoform X1 [KO:K04215]
116056393  [KO:K05840]
116056563  gna14a; guanine nucleotide-binding protein subunit alpha-14 [KO:K04636]
116056574  [KO:K04634]
116056635  [KO:K02649]
116056716  bmpr1ba; bone morphogenetic protein receptor type-1B [KO:K13578] [EC:2.7.11.30]
116056835  [KO:K04501]
116056966  pthlha; parathyroid hormone-like hormone a [KO:K22608]
116056995  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X2 [KO:K02649]
116057032  [KO:K04280]
116057111  pnoca; prepronociceptin [KO:K25696]
116057222  gng13a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13a [KO:K04547]
116057296  [KO:K05087] [EC:2.7.10.1]
116057356  gna11b; guanine nucleotide-binding protein subunit alpha-11b isoform X1 [KO:K04635]
116057395  gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
116057550  acvr1l; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
116057568  [KO:K07826]
116057716  ghsra; growth hormone secretagogue receptor a [KO:K04284]
116057948  [KO:K05858] [EC:3.1.4.11]
116058272  gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
116058511  [KO:K04280]
116058689  pdyn; proenkephalin-B [KO:K15840]
116058699  igf3; insulin-like growth factor 3 [KO:K05459]
116058705  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
116059061  oprl1; nociceptin receptor [KO:K04216]
116059342  [KO:K08049] [EC:4.6.1.1]
116059357  [KO:K04228]
116059411  gper1; G-protein coupled estrogen receptor 1 [KO:K04246]
116059418  [KO:K04218]
116059452  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1 [KO:K04345] [EC:2.7.11.11]
116059523  gcgra; glucagon receptor [KO:K04583]
116059575  hcrt; orexin [KO:K05246]
116059590  [KO:K04221]
116059592  [KO:K04347]
116059636  stat5a; signal transducer and activator of transcription 5A isoform X1 [KO:K11224]
116059637  stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
116059674  ramp2; receptor activity-modifying protein 2 isoform X1 [KO:K08448]
116060027  adipor2; adiponectin receptor protein 2 [KO:K07297]
116060043  gnai1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
116060060  igf1; insulin-like growth factor I [KO:K05459]
116060134  pmch; pro-MCH isoform X1 [KO:K05229]
116060211  ucn3l; urocortin 3, like [KO:K05257]
116060276  si:ch73-265d7.2; C-type natriuretic peptide 2 [KO:K12336]
116060326  uts1; urotensin 1 [KO:K23142]
116060396  [KO:K04526]
116060489  drd2l; dopamine receptor D2 like isoform X2 [KO:K04145]
116060593  mc1r; melanocyte-stimulating hormone receptor [KO:K04199]
116060601  [KO:K23106]
116060644  gnao1b; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b [KO:K04534]
116060931  gngt2b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2b [KO:K04549]
116061025  thrab; thyroid hormone receptor alpha isoform X1 [KO:K05547]
116061103  [KO:K04639]
116061138  [KO:K05840]
116061196  fshr; follicle-stimulating hormone receptor [KO:K04247]
116061340  [KO:K08447]
116061369  [KO:K06493]
116061374  pth3r; parathyroid hormone 3 receptor [KO:K04585]
116061376  [KO:K04578]
116061397  adrb1; beta-1 adrenergic receptor [KO:K04141]
116061694  lhb; gonadotropin subunit beta-2 [KO:K08521]
116061747  [KO:K05858] [EC:3.1.4.11]
116061787  [KO:K05264]
116061955  ins; insulin [KO:K04526]
116062017  trh; pro-thyrotropin-releasing hormone [KO:K05253]
116062021  [KO:K04145]
116062135  [KO:K05251]
116062169  [KO:K08046] [EC:4.6.1.1]
116062773  [KO:K04634]
116062796  prlra; prolactin receptor a isoform X1 [KO:K05081]
116062801  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
116063044  gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
116063082  [KO:K04630]
116063320  si:dkey-204f11.64; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
116063453  amh; muellerian-inhibiting factor isoform X1 [KO:K04665]
116063484  dio1; type I iodothyronine deiodinase [KO:K01562] [EC:1.21.99.4]
116063486  ghrhrl; growth hormone releasing hormone receptor, like [KO:K04584]
116063513  si:dkey-44g17.6; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
116063544  gh1; somatotropin [KO:K05438]
116063796  gng13b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13b [KO:K04547]
116063920  itgb3a; integrin beta-3a [KO:K06493]
116063931  [KO:K05266]
116064015  sstr3; somatostatin receptor type 5 [KO:K04219]
116064328  adra2db; alpha-2Db adrenergic receptor [KO:K04140]
116064450  drd1a; D(1) dopamine receptor [KO:K04144]
116064454  [KO:K04136]
116064503  [KO:K05054]
116064516  [KO:K12324] [EC:4.6.1.2]
116064632  [KO:K12323] [EC:4.6.1.2]
116064881  [KO:K14735] [EC:1.16.3.1]
116064885  [KO:K14735] [EC:1.16.3.1]
116064894  gng8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
116064954  si:ch211-284e13.4; insulin receptor substrate 1-B [KO:K16172]
116064964  gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
116065327  gnrh2; progonadoliberin-2 [KO:K05252]
116065356  gucy2c; heat-stable enterotoxin receptor isoform X2 [KO:K12320] [EC:4.6.1.2]
116065462  mchr1b; melanin-concentrating hormone receptor 1 [KO:K04320]
116065893  drd4-rs; dopamine receptor D4 related sequence [KO:K04147]
116066218  esr1; estrogen receptor isoform X1 [KO:K08550]
116066254  [KO:K08043] [EC:4.6.1.1]
116066255  si:dkey-206f10.1; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
116066258  gcgb; glucagon b [KO:K05259]
116066262  [KO:K05228]
116066349  esr2a; estrogen receptor 2a isoform X1 [KO:K08551]
116066422  adipor1a; adiponectin receptor protein 1a [KO:K07297]
116066486  prkg3; cGMP-dependent protein kinase 2 [KO:K19477] [EC:2.7.11.12]
116066597  [KO:K08043] [EC:4.6.1.1]
116066910  gngt1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
116066985  calcr; calcitonin gene-related peptide type 1 receptor [KO:K04576]
116067017  adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
116067149  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
116067281  [KO:K04140]
116067285  drd4b; dopamine receptor D4b [KO:K04147]
116067487  [KO:K11224]
118493193  [KO:K08521]
118494100  [KO:K04135]
118494309  [KO:K05258]
Compound
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00788  L-Adrenaline
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01829  Thyroxine
C02017  Corticotropin
C02210  beta-Endorphin
C02465  Triiodothyronine
C02758  alpha-Melanotropin
C03758  Dopamine
C14818  Fe2+
C14819  Fe3+
C16000  Urodilatin
C16048  Glucagon-like peptide 1
C16125  Calcitonin gene-related peptide 1
C16126  Calcitonin gene-related peptide 2
C16136  beta-Melanotropin
C16137  gamma-Melanotropin
Reference
  Authors
Trubacova R, Drastichova Z, Novotny J
  Title
Biochemical and physiological insights into TRH receptor-mediated signaling.
  Journal
Front Cell Dev Biol 10:981452 (2022)
DOI:10.3389/fcell.2022.981452
Reference
  Authors
Velez EJ, Unniappan S
  Title
A Comparative Update on the Neuroendocrine Regulation of Growth Hormone in Vertebrates.
  Journal
Front Endocrinol (Lausanne) 11:614981 (2020)
DOI:10.3389/fendo.2020.614981
Reference
  Authors
Kumar U
  Title
Somatostatin and Somatostatin Receptors in Tumour Biology.
  Journal
Int J Mol Sci 25:ijms25010436 (2023)
DOI:10.3390/ijms25010436
Reference
  Authors
Kahnamouyi S, Nouri M, Farzadi L, Darabi M, Hosseini V, Mehdizadeh A
  Title
The role of mitogen-activated protein kinase-extracellular receptor kinase pathway in female fertility outcomes: a focus on pituitary gonadotropins  regulation.
  Journal
Ther Adv Endocrinol Metab 9:209-215 (2018)
DOI:10.1177/2042018818772775
Reference
  Authors
Deussing JM, Chen A
  Title
The Corticotropin-Releasing Factor Family: Physiology of the Stress Response.
  Journal
Physiol Rev 98:2225-2286 (2018)
DOI:10.1152/physrev.00042.2017
Reference
  Authors
Li Y, Yuan Q, He X, Zhang Y, You C, Wu C, Li J, Xu HE, Zhao LH
  Title
Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
  Journal
Cell Discov 10:91 (2024)
DOI:10.1038/s41421-024-00724-6
Reference
  Authors
Wang C, Wang Q, Ji B, Pan Y, Xu C, Cheng B, Bai B, Chen J
  Title
The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.
  Journal
Front Mol Neurosci 11:220 (2018)
DOI:10.3389/fnmol.2018.00220
Reference
  Authors
Bencze J, Pocsai K, Murnyak B, Gergely PA, Juhasz B, Szilvassy Z, Hortobagyi T
  Title
The Melanin-concentrating Hormone System in Human, Rodent and Avian Brain.
  Journal
Open Med (Wars) 13:264-269 (2018)
DOI:10.1515/med-2018-0040
Reference
  Authors
Lin YT, Hsu KS
  Title
Oxytocin receptor signaling in the hippocampus: Role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social  memory.
  Journal
Prog Neurobiol 171:1-14 (2018)
DOI:10.1016/j.pneurobio.2018.10.003
Reference
  Authors
Perisic M, Woolcock K, Hering A, Mendel H, Muttenthaler M
  Title
Oxytocin and vasopressin signaling in health and disease.
  Journal
Trends Biochem Sci 49:361-377 (2024)
DOI:10.1016/j.tibs.2024.01.010
Reference
  Authors
Che T, Roth BL
  Title
Molecular basis of opioid receptor signaling.
  Journal
Cell 186:5203-5219 (2023)
DOI:10.1016/j.cell.2023.10.029
Reference
  Authors
Jing L, Zhang Q
  Title
Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion.
  Journal
Front Endocrinol (Lausanne) 13:992883 (2022)
DOI:10.3389/fendo.2022.992883
Reference
  Authors
Hu B, Li H, Zhang X
  Title
A Balanced Act: The Effects of GH-GHR-IGF1 Axis on Mitochondrial Function.
  Journal
Front Cell Dev Biol 9:630248 (2021)
DOI:10.3389/fcell.2021.630248
Reference
  Authors
Gloaguen P, Crepieux P, Heitzler D, Poupon A, Reiter E
  Title
Mapping the follicle-stimulating hormone-induced signaling networks.
  Journal
Front Endocrinol (Lausanne) 2:45 (2011)
DOI:10.3389/fendo.2011.00045
Reference
  Authors
Johnson GP, Jonas KC
  Title
Mechanistic insight into how gonadotropin hormone receptor complexes direct signalingdagger.
  Journal
Biol Reprod 102:773-783 (2020)
DOI:10.1093/biolre/ioz228
Reference
  Authors
Wu CS, Cioanca AV, Gelmi MC, Wen L, Di Girolamo N, Zhu L, Natoli R, Conway RM, Petsoglou C, Jager MJ, McCluskey PJ, Madigan MC
  Title
The multifunctional human ocular melanocortin system.
  Journal
Prog Retin Eye Res 95:101187 (2023)
DOI:10.1016/j.preteyeres.2023.101187
Reference
  Authors
Standing D, Dandawate P, Anant S
  Title
Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies.
  Journal
Front Endocrinol (Lausanne) 13:1112987 (2022)
DOI:10.3389/fendo.2022.1112987
Reference
  Authors
Mendoza A, Hollenberg AN
  Title
New insights into thyroid hormone action.
  Journal
Pharmacol Ther 173:135-145 (2017)
DOI:10.1016/j.pharmthera.2017.02.012
Reference
  Authors
Gupta P, Furness SGB, Bittencourt L, Hare DL, Wookey PJ
  Title
Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma.
  Journal
Ther Adv Med Oncol 12:1758835920978110 (2020)
DOI:10.1177/1758835920978110
Reference
  Authors
Lombardi G, Ziemann E, Banfi G, Corbetta S
  Title
Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.
  Journal
Int J Mol Sci 21:ijms21155388 (2020)
DOI:10.3390/ijms21155388
Reference
  Authors
Mani I, Pandey KN
  Title
Emerging concepts of receptor endocytosis and concurrent intracellular signaling: Mechanisms of guanylyl cyclase/natriuretic peptide receptor-A activation and  trafficking.
  Journal
Cell Signal 60:17-30 (2019)
DOI:10.1016/j.cellsig.2019.03.022
Reference
  Authors
Perez DM
  Title
alpha(1)-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition.
  Journal
Front Pharmacol 11:581098 (2020)
DOI:10.3389/fphar.2020.581098
Reference
  Authors
Feng Y, Lu Y
  Title
Immunomodulatory Effects of Dopamine in Inflammatory Diseases.
  Journal
Front Immunol 12:663102 (2021)
DOI:10.3389/fimmu.2021.663102
Reference
  Authors
Colin M, Delaitre C, Foulquier S, Dupuis F
  Title
The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System.
  Journal
Molecules 28:molecules28145481 (2023)
DOI:10.3390/molecules28145481
Reference
  Authors
Bogdan AR, Miyazawa M, Hashimoto K, Tsuji Y
  Title
Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.
  Journal
Trends Biochem Sci 41:274-86 (2016)
DOI:10.1016/j.tibs.2015.11.012
Reference
  Authors
Rajoria B, Zhang X, Yee D
  Title
IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells.
  Journal
Int J Mol Sci 24:ijms241210209 (2023)
DOI:10.3390/ijms241210209
Reference
  Authors
Arneth B, Arneth R, Shams M
  Title
Metabolomics of Type 1 and Type 2 Diabetes.
  Journal
Int J Mol Sci 20:ijms20102467 (2019)
DOI:10.3390/ijms20102467
Reference
  Authors
Kajani S, Laker RC, Ratkova E, Will S, Rhodes CJ
  Title
Hepatic glucagon action: beyond glucose mobilization.
  Journal
Physiol Rev 104:1021-1060 (2024)
DOI:10.1152/physrev.00028.2023
Reference
  Authors
Silvestro M, Iannone LF, Orologio I, Tessitore A, Tedeschi G, Geppetti P, Russo A
  Title
Migraine Treatment: Towards New Pharmacological Targets.
  Journal
Int J Mol Sci 24:ijms241512268 (2023)
DOI:10.3390/ijms241512268
Reference
  Authors
Elliott S, Sinclair A, Collins H, Rice L, Jelkmann W
  Title
Progress in detecting cell-surface protein receptors: the erythropoietin receptor example.
  Journal
Ann Hematol 93:181-92 (2014)
DOI:10.1007/s00277-013-1947-2
Reference
  Authors
van Loenen MR, Geenen B, Arnoldussen IAC, Kiliaan AJ
  Title
Ghrelin as a prominent endocrine factor in stress-induced obesity.
  Journal
Nutr Neurosci 25:1413-1424 (2022)
DOI:10.1080/1028415X.2020.1863740
Reference
  Authors
Zeng Q, Ou L, Wang W, Guo DY
  Title
Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes.
  Journal
Front Endocrinol (Lausanne) 11:112 (2020)
DOI:10.3389/fendo.2020.00112
Reference
  Authors
Takei Y
  Title
Evolution of the membrane/particulate guanylyl cyclase: From physicochemical sensors to hormone receptors.
  Journal
Gen Comp Endocrinol 315:113797 (2022)
DOI:10.1016/j.ygcen.2021.113797
Reference
  Authors
Seino Y, Fukushima M, Yabe D
  Title
GIP and GLP-1, the two incretin hormones: Similarities and differences.
  Journal
J Diabetes Investig 1:8-23 (2010)
DOI:10.1111/j.2040-1124.2010.00022.x
Reference
  Authors
Langer I, Jeandriens J, Couvineau A, Sanmukh S, Latek D
  Title
Signal Transduction by VIP and PACAP Receptors.
  Journal
Biomedicines 10:406 (2022)
DOI:10.3390/biomedicines10020406
Reference
  Authors
Kitazawa T, Kaiya H
  Title
Motilin Comparative Study: Structure, Distribution, Receptors, and Gastrointestinal Motility.
  Journal
Front Endocrinol (Lausanne) 12:700884 (2021)
DOI:10.3389/fendo.2021.700884
Reference
  Authors
Cate RL
  Title
Anti-Mullerian Hormone Signal Transduction involved in Mullerian Duct Regression.
  Journal
Front Endocrinol (Lausanne) 13:905324 (2022)
DOI:10.3389/fendo.2022.905324
Reference
  Authors
Rettberg JR, Yao J, Brinton RD
  Title
Estrogen: a master regulator of bioenergetic systems in the brain and body.
  Journal
Front Neuroendocrinol 35:8-30 (2014)
DOI:10.1016/j.yfrne.2013.08.001
Reference
  Authors
Prossnitz ER, Barton M
  Title
The G protein-coupled oestrogen receptor GPER in health and disease: an update.
  Journal
Nat Rev Endocrinol 19:407-424 (2023)
DOI:10.1038/s41574-023-00822-7
Reference
  Authors
Roy B, Palaniyandi SS
  Title
Tissue-specific role and associated downstream signaling pathways of adiponectin.
  Journal
Cell Biosci 11:77 (2021)
DOI:10.1186/s13578-021-00587-4
Reference
  Authors
Liu J, Lai F, Hou Y, Zheng R
  Title
Leptin signaling and leptin resistance.
  Journal
Med Rev (2021) 2:363-384 (2022)
DOI:10.1515/mr-2022-0017
Reference
  Authors
Kuter DJ
  Title
Treatment of chemotherapy-induced thrombocytopenia in patients with non-hematologic malignancies.
  Journal
Haematologica 107:1243-1263 (2022)
DOI:10.3324/haematol.2021.279512
Related
pathway
sluc04020  Calcium signaling pathway
KO pathway
ko04081   

DBGET integrated database retrieval system