Network variation - IgSF CAM signaling
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Network variation - IgSF CAM signaling
|
| ENTRY | nt06546 |
| Name | IgSF CAM signaling |
| Category | Pathway view; Cellular process |
| Pathway | hsa04517 IgSF CAM signaling hsa04514 Cell adhesion molecules hsa04360 Axon guidance hsa04520 Adherens junction hsa04530 Tight junction |
| Display | drug-target relation disease type |
| Disease name | Disease category | ||
| LCCS11 | H00865 | Lethal congenital contractural syndrome | Congenital malformation |
| NEDNMS | H02397 | Neurodevelopmental disorder with movement abnormalities or hypotonia | Congenital malformation |
| SPG1/MASA/HSAS | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| H01034 | L1 syndrome | Congenital malformation | |
| H02178 | MASA syndrome | Nervous system disease | |
| H02458 | Hydrocephalus due to congenital stenosis of aqueduct of Sylvius | Congenital malformation | |
| NEDCPMD | H02459 | Syndromic neurodevelopmental disorder | Congenital malformation |
| LQT4 | H00720 | Long QT syndrome | Cardiovascular disease |
| MRT37 | H00768 | Autosomal recessive intellectual developmental disorder | Mental and behavioural disorder |
| SPG91/DEE5/HMND11/DEVEP | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| H00606 | Early infantile epileptic encephalopathy | Nervous system disease | |
| H00856 | Distal hereditary motor neuropathies | Nervous system disease | |
| H02989 | Developmental delay with or without epilepsy | Nervous system disease | |
| DDISBA | H02685 | Developmental delay with neuropsychiatric disorders | Congenital malformation |
| SCA5/SCAR14 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| H01891 | Autosomal recessive spinocerebellar ataxias | Neurodegenerative disease | |
| CMND | H01810 | Congenital myopathy | Nervous system disease |
| DEE7/BFNS1 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| H00806 | Benign familial neonatal seizure | Nervous system disease | |
| BFNS2 | H00806 | Benign familial neonatal seizure | Nervous system disease |
| BFIS5/MYOCL2/CIAT | H02362 | Benign familial infantile seizure | Nervous system disease |
| H02789 | Familial myoclonus | Nervous system disease | |
| H02980 | Cognitive impairment with or without cerebellar ataxia | Nervous system disease | |
| DEE13 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| AD1/CAA | H00056 | Alzheimer disease | Neurodegenerative disease |
| H01185 | Cerebral amyloid angiopathy | Neurodegenerative disease | |
| CMYO12 | H01810 | Congenital myopathy | Nervous system disease |
| LCCS7/CHN3 | H00865 | Lethal congenital contractural syndrome | Congenital malformation |
| H02357 | Congenital hypomyelinating neuropathy | Nervous system disease | |
| FAME5 | H02213 | Familial adult myoclonic epilepsy | Nervous system disease |
| PTHSL1/AUTS15 | H00756 | Pitt-Hopkins syndrome | Congenital malformation |
| H02111 | Autism | Mental and behavioural disorder | |
| EA1 | H00749 | Episodic ataxias | Nervous system disease |
| DEE32 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| MCIDDS | H02132 | Microcephaly syndrome | Congenital malformation |
| CMT1B/2I/2J/4E/RLS/CHN2/DSD | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| H01155 | Roussy-Levy syndrome | Nervous system disease | |
| H02357 | Congenital hypomyelinating neuropathy | Nervous system disease | |
| H02359 | Dejerine-Sottas disease | Nervous system disease | |
| CMT1B | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| CMT1E/RLS/HNPP/GBS/DSD | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| H01155 | Roussy-Levy syndrome | Nervous system disease | |
| H01296 | Hereditary neuropathy with liability to pressure palsies | Nervous system disease | |
| H01436 | Guillain-Barre syndrome | Nervous system disease | |
| H02359 | Dejerine-Sottas disease | Nervous system disease | |
| CMT1A | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| CMT1G | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| SPG75 | H00266 | Hereditary spastic paraplegia | Nervous system disease |
| MRMV4 | H01287 | Congenital mirror movements | Nervous system disease |
| ESCC/CRC/MRMV1/HGPPS2 | H00017 | Esophageal cancer | Cancer |
| H00020 | Colorectal cancer | Cancer | |
| H01287 | Congenital mirror movements | Nervous system disease | |
| H02450 | Horizontal gaze palsy with progressive scoliosis | Nervous system disease | |
| NS1/JMML/LPRD1 | H01738 | Noonan syndrome | Congenital malformation |
| H02541 | Juvenile myelomonocytic leukemia | Cancer | |
| H01984 | Leopard syndrome | Congenital malformation | |
| NYS8/CPHD8/NORS | H00776 | Congenital motor nystagmus (CMN) | Nervous system disease |
| H02036 | Combined pituitary hormone deficiency | Endocrine and metabolic disease | |
| H02981 | Neurooculorenal syndrome | Congenital malformation | |
| VUR2 | H01037 | Vesicoureteral reflux | Urinary system disease |
| AOVD3 | H00554 | Aortic valve disease | Congenital malformation |
| NMTC2 | H00032 | Thyroid cancer | Cancer |
| CHDSKM | H02982 | Congenital heart defects and skeletal malformations syndrome | Congenital malformation |
| TKS | H02667 | Takenouchi-Kosaki syndrome | Congenital malformation |
| IDDMSSD | H02463 | Syndromic intellectual developmental disorder | Mental and behavioural disorder |
| KNO2 | H02074 | Knobloch syndrome | Congenital malformation |
| XLID30 | H00480 | X-linked intellectual developmental disorder | Mental and behavioural disorder |
| MATINS/DFNA17 | H00233 | MYH9-related disease | Cardiovascular disease |
| H00604 | Deafness, autosomal dominant | Nervous system disease | |
| DFNA4A/PNMHH | H00604 | Deafness, autosomal dominant | Nervous system disease |
| H02817 | Peripheral neuropathy, myopathy, hoarseness, and hearing loss | Nervous system disease | |
| MMIHS4 | H01869 | Megacystis microcolon intestinal hypoperistalsis syndrome | Congenital malformation |
| NPHS1 | H01657 | Nephrotic syndrome | Urinary system disease |
| NPHS23 | H01657 | Nephrotic syndrome | Urinary system disease |
| NPHS2 | H01657 | Nephrotic syndrome | Urinary system disease |
| FSGS3 | H00626 | Focal segmental glomerulosclerosis | Urinary system disease |
| FSGS2 | H00626 | Focal segmental glomerulosclerosis | Urinary system disease |
| Afibrinogenemia/Amyloidosis/AMYLD2 | H00222 | Congenital fibrinogen deficiency | Hematologic disease |
| H00845 | Familial amyloidosis | Nervous system disease | |
| Afibrinogenemia | H00222 | Congenital fibrinogen deficiency | Hematologic disease |
| TB/HIV susceptibility | H00342 | Tuberculosis | Bacterial infectious disease |
| H01563 | HIV infection | Viral infectious disease | |
| Malaria susceptibility | H00361 | Malaria | Parasitic infectious disease |
| DFNB24 | H00605 | Deafness, autosomal recessive | Nervous system disease |
| IMD50 | H00093 | Combined immunodeficiency | Primary immunodeficiency |
| BDPLT15 | H01235 | Bleeding disorder platelet-type | Hematologic disease |
| CMD1AA/CMH23/MPD6/CMYO8 | H00292 | Hypertrophic cardiomyopathy | Cardiovascular disease |
| H00294 | Dilated cardiomyopathy | Cardiovascular disease | |
| H00594 | Distal myopathy | Nervous system disease | |
| H01810 | Congenital myopathy | Nervous system disease | |
| FSGS1 | H00626 | Focal segmental glomerulosclerosis | Urinary system disease |
| RA | H00630 | Rheumatoid arthritis | Immune system disease |
| XLP1 | H01969 | X-linked lymphoproliferative syndrome | Primary immunodeficiency |
| OPS | H01828 | Opsismodysplasia | Congenital malformation |
| BCC1/CMAVM1 | H00039 | Basal cell carcinoma | Cancer |
| H02043 | Capillary malformation-arteriovenous malformation | Congenital malformation | |
| GT2 | H00226 | Glanzmann thrombasthenia | Hematologic disease |
| BDPLT24 | H01235 | Bleeding disorder platelet-type | Hematologic disease |
| LAD1 | H00099 | Leukocyte adhesion deficiency | Primary immunodeficiency |
| IBGC8 | H01574 | Familial idiopathic basal ganglia calcification | Nervous system disease |
| HDBSCC | H01301 | Hemorrhagic destruction of the brain, subependymal calcification, and cataracts | Nervous system disease |
| NEDIHSS | H02988 | Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity | Congenital malformation |
| CSBS | H01477 | Congenital short bowel syndrome | Congenital malformation |
| PFIC4/FHCA1 | H00624 | Progressive familial intrahepatic cholestasis | Inherited metabolic disorder |
| H01935 | Familial hypercholanemia | Inherited metabolic disorder | |
| SGBS1 | H01215 | Simpson-Golabi-Behmel syndrome | Congenital malformation |
| KPTS | H02326 | Keipert syndrome | Congenital malformation |
| OMOD1 | H02154 | Omodysplasia | Congenital malformation |
| SJS/DDSH | H01777 | Schwartz-Jampel syndrome | Nervous system disease |
| H02155 | Dyssegmental dysplasia | Congenital malformation | |
| TS/TTM | H00862 | Tourette syndrome | Mental and behavioural disorder |
| H00864 | Trichotillomania | Mental and behavioural disorder | |
| XLID111 | H00480 | X-linked intellectual developmental disorder | Mental and behavioural disorder |
| DFNMYP | H02355 | Deafness and myopia | Nervous system disease |
| XLID21 | H00480 | X-linked intellectual developmental disorder | Mental and behavioural disorder |
| AS/AUTSX1 | H01882 | Asperger syndrome | Mental and behavioural disorder |
| H02111 | Autism | Mental and behavioural disorder | |
| BNAH | H02811 | Aplasia or hypoplasia of the breasts and/or nipples | Congenital malformation |
| NEDPACH | H02911 | Paul-Chao neurodevelopmental syndrome | Congenital malformation |
| FGS4/MICPCH | H00894 | FG syndrome | Congenital malformation |
| H01921 | MICPCH syndrome | Congenital malformation | |
| MRD44 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRD63 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| OFC7/CLPED1 | H00516 | Cleft lip and/or cleft palate | Congenital malformation |
| H02456 | Ectodermal dysplasia | Congenital malformation | |
| EDSS | H00647 | Ectodermal dysplasia-syndactyly syndrome | Congenital malformation |
| CMT2FF | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| C Syndrome | H01008 | C syndrome | Congenital malformation |
| MRD11 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |