KEGG   PATHWAY: lav04060
Entry
lav04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Loxodonta africana (African savanna elephant)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
lav04060  Cytokine-cytokine receptor interaction
lav04060

Organism
Loxodonta africana (African savanna elephant) [GN:lav]
Gene
100169649  CCR5; chemokine (C-C motif) receptor 5 [KO:K04180]
100653529  GDF11; LOW QUALITY PROTEIN: growth/differentiation factor 11 [KO:K22679]
100653621  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
100653832  TGFB3; transforming growth factor beta-3 isoform X1 [KO:K13377]
100653995  ACVRL1; serine/threonine-protein kinase receptor R3 [KO:K13594] [EC:2.7.11.30]
100654115  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
100654129  IL23R; interleukin-23 receptor [KO:K05065]
100654245  IL9R; interleukin-9 receptor isoform X1 [KO:K05073]
100654281  ACVR1B; activin receptor type-1B isoform X1 [KO:K13567] [EC:2.7.11.30]
100654327  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
100654399  IL31RA; interleukin-31 receptor subunit alpha [KO:K22630]
100654499  NGF; beta-nerve growth factor [KO:K02582]
100654812  PRL; prolactin [KO:K05439]
100654822  IL4R; interleukin-4 receptor subunit alpha [KO:K05071]
100654870  NODAL; nodal homolog [KO:K04666]
100654878  BMP2; bone morphogenetic protein 2 [KO:K21283]
100654892  [KO:K21092]
100655062  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
100655109  IL21R; LOW QUALITY PROTEIN: interleukin-21 receptor [KO:K05075]
100655202  [KO:K05419]
100655361  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
100655463  [KO:K05408]
100655626  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
100655634  [KO:K16062]
100655653  EDAR; tumor necrosis factor receptor superfamily member EDAR [KO:K05162]
100655749  [KO:K05408]
100655766  ACKR3; atypical chemokine receptor 3 [KO:K04304]
100655906  IL11RA; LOW QUALITY PROTEIN: interleukin-11 receptor subunit alpha [KO:K05056]
100655908  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
100655923  IL15RA; interleukin-15 receptor subunit alpha [KO:K05074]
100656085  IL23A; interleukin-23 subunit alpha [KO:K05426]
100656112  GDF3; growth/differentiation factor 3 [KO:K22672]
100656286  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
100656395  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
100656398  IL2; interleukin-2 [KO:K05429]
100656534  TGFB2; transforming growth factor beta-2 isoform X2 [KO:K13376]
100656684  IL21; interleukin-21 [KO:K05434]
100656930  RELL2; RELT-like protein 2 isoform X2 [KO:K26541]
100657097  IL27; interleukin-27 subunit alpha [KO:K22629]
100657211  IL12B; interleukin-12 subunit beta [KO:K05425]
100657422  [KO:K05440]
100657454  BMP3; bone morphogenetic protein 3 [KO:K05496]
100657514  [KO:K05440]
100657564  IL15; interleukin-15 [KO:K05433]
100657655  CSF3; granulocyte colony-stimulating factor isoform X6 [KO:K05423]
100657709  INHBA; inhibin beta A chain [KO:K04667]
100657715  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
100657834  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
100658031  ACVR2B; LOW QUALITY PROTEIN: activin receptor type-2B [KO:K13596] [EC:2.7.11.30]
100658123  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
100658284  IL7; interleukin-7 [KO:K05431]
100658408  IL18RAP; interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
100658487  IL19; interleukin-19 [KO:K05444]
100658503  CCR7; C-C chemokine receptor type 7 isoform X2 [KO:K04182]
100658560  LIFR; LOW QUALITY PROTEIN: leukemia inhibitory factor receptor [KO:K05058]
100658768  IL20; interleukin-20 isoform X1 [KO:K22667]
100658874  BMP8A; bone morphogenetic protein 8A [KO:K16622]
100659000  CD40LG; CD40 ligand [KO:K03161]
100659053  IL24; interleukin-24 [KO:K22668]
100659089  LIF; leukemia inhibitory factor [KO:K05419]
100659421  IL17RB; interleukin-17 receptor B [KO:K05165]
100659658  CTF1; cardiotrophin-1 isoform X1 [KO:K05422]
100659699  IFNE; interferon epsilon [KO:K05442]
100659733  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
100659737  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
100659836  CXCL11; C-X-C motif chemokine 11 [KO:K12672]
100659865  [KO:K22669]
100659923  TNFRSF4; tumor necrosis factor receptor superfamily member 4 [KO:K05142]
100659942  [KO:K24382]
100659984  [KO:K05414]
100660007  TNFRSF8; tumor necrosis factor receptor superfamily member 8 [KO:K05145]
100660010  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
100660116  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
100660146  [KO:K22669]
100660192  [KO:K04177]
100660194  BMPR1B; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
100660206  TNFRSF18; tumor necrosis factor receptor superfamily member 18 isoform X1 [KO:K05154]
100660270  [KO:K05414]
100660403  IL17D; LOW QUALITY PROTEIN: interleukin-17D [KO:K05492]
100660404  CXCL9; C-X-C motif chemokine 9 [KO:K05416]
100660429  [KO:K22669]
100660478  [KO:K04178]
100660554  [KO:K05414]
100660616  OSM; oncostatin-M isoform X3 [KO:K05418]
100660744  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
100660760  GHR; growth hormone receptor [KO:K05080]
100660846  IL6; interleukin-6 [KO:K05405]
100660848  [KO:K05440]
100660906  [KO:K05419]
100660966  IL17RE; interleukin-17 receptor E [KO:K05168]
100661057  CCR9; C-C chemokine receptor type 9 isoform X1 [KO:K04184]
100661135  [KO:K05414]
100661208  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
100661365  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
100661419  [KO:K05440]
100661481  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
100661600  BMPR2; LOW QUALITY PROTEIN: bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
100661776  CD70; CD70 antigen [KO:K05470]
100661891  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
100661986  [KO:K05414]
100662052  RELT; tumor necrosis factor receptor superfamily member 19L isoform X3 [KO:K05156]
100662131  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
100662146  CNTF; ciliary neurotrophic factor [KO:K05420]
100662380  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
100662586  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
100662597  [KO:K05474]
100662689  CCL20; C-C motif chemokine 20 isoform X3 [KO:K14625]
100662713  GDF9; growth/differentiation factor 9 isoform X2 [KO:K22673]
100662737  IFNK; interferon kappa [KO:K05441]
100662800  ACKR4; atypical chemokine receptor 4 [KO:K04186]
100662817  AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 [KO:K04672] [EC:2.7.11.30]
100662831  [KO:K05414]
100662962  [KO:K05438]
100663041  IL17RA; interleukin-17 receptor A isoform X1 [KO:K05164]
100663051  THPO; LOW QUALITY PROTEIN: thrombopoietin [KO:K06854]
100663082  [KO:K05419]
100663246  [KO:K05407]
100663285  IFNG; interferon gamma [KO:K04687]
100663365  [KO:K05419]
100663523  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
100663528  PPBP; platelet basic protein [KO:K10029]
100663565  IL5; interleukin-5 [KO:K05428]
100663567  [KO:K05445]
100663685  [KO:K05414]
100663800  CCR1; C-C chemokine receptor type 1 [KO:K04176]
100663814  [KO:K05506]
100663851  [KO:K05078]
100663852  [KO:K05445]
100663871  LEP; leptin [KO:K05424]
100663910  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
100664082  XCR1; chemokine XC receptor 1 [KO:K04193]
100664099  CXCL8; interleukin-8 [KO:K10030]
100664139  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1 [KO:K05066]
100664140  [KO:K05445]
100664198  IL6R; interleukin-6 receptor subunit alpha [KO:K05055]
100664366  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
100664424  [KO:K05445]
100664727  PRLR; prolactin receptor [KO:K05081]
100664834  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
100665125  TNFRSF9; tumor necrosis factor receptor superfamily member 9 isoform X4 [KO:K05146]
100665129  [KO:K05505]
100665137  IL12A; interleukin-12 subunit alpha [KO:K05406]
100665172  IFNGR1; interferon gamma receptor 1 [KO:K05132]
100665300  [KO:K05440]
100665398  IL10; interleukin-10 isoform X2 [KO:K05443]
100665401  GDF7; LOW QUALITY PROTEIN: growth/differentiation factor 7 [KO:K20013]
100665573  [KO:K05050]
100665583  [KO:K05414]
100665693  CXCR3; C-X-C chemokine receptor type 3 isoform X1 [KO:K04188]
100665706  CSF3R; LOW QUALITY PROTEIN: granulocyte colony-stimulating factor receptor [KO:K05061]
100665796  LEPR; leptin receptor isoform X1 [KO:K05062]
100665867  [KO:K05440]
100666028  IL20RA; interleukin-20 receptor subunit alpha [KO:K05136]
100666130  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
100666154  [KO:K05440]
100666176  IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
100666178  CD40; tumor necrosis factor receptor superfamily member 5 [KO:K03160]
100666267  EPOR; LOW QUALITY PROTEIN: erythropoietin receptor [KO:K05079]
100666284  [KO:K05481]
100666438  IFNB1; interferon beta [KO:K05415]
100666495  BMP7; bone morphogenetic protein 7 [KO:K16621]
100666568  [KO:K05483]
100666654  IL1RAP; interleukin-1 receptor accessory protein isoform X2 [KO:K04723]
100666666  CCR8; C-C chemokine receptor type 8 [KO:K04183]
100666676  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
100666694  BMP5; bone morphogenetic protein 5 [KO:K04663]
100666698  IL9; interleukin-9 [KO:K05432]
100666724  OSMR; oncostatin-M-specific receptor subunit beta [KO:K05057]
100666834  EDA; LOW QUALITY PROTEIN: ectodysplasin-A [KO:K05480]
100666858  IL17C; LOW QUALITY PROTEIN: interleukin-17C [KO:K05491]
100666899  ACVR1; activin receptor type-1 isoform X2 [KO:K04675] [EC:2.7.11.30]
100666949  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
100667054  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A isoform X2 [KO:K05149]
100667125  IL1R2; interleukin-1 receptor type 2 isoform X2 [KO:K04387]
100667186  ACVR1C; activin receptor type-1C isoform X2 [KO:K13568] [EC:2.7.11.30]
100667304  IFNGR2; interferon gamma receptor 2 isoform X1 [KO:K05133]
100667317  GDF1; LOW QUALITY PROTEIN: embryonic growth/differentiation factor 1 [KO:K05495]
100667327  MPL; LOW QUALITY PROTEIN: thrombopoietin receptor [KO:K05082]
100667586  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
100667634  TGFB1; transforming growth factor beta-1 [KO:K13375]
100667692  IL1RL2; interleukin-1 receptor-like 2 [KO:K05172]
100667872  IL10RB; interleukin-10 receptor subunit beta isoform X2 [KO:K05135]
100667977  IL1RL1; interleukin-1 receptor-like 1 isoform X2 [KO:K05171]
100668255  GDF5; growth/differentiation factor 5 [KO:K04664]
100668369  IL18; interleukin-18 isoform X1 [KO:K05482]
100668466  [KO:K16597]
100668516  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
100668578  CCR6; C-C chemokine receptor type 6 [KO:K04181]
100668655  CCL24; C-C motif chemokine 24 isoform X2 [KO:K21097]
100668743  [KO:K16596]
100668777  IL17B; interleukin-17B [KO:K05490]
100668887  IL26; LOW QUALITY PROTEIN: interleukin-26 [KO:K05446]
100668936  IL34; interleukin-34 isoform X1 [KO:K22633]
100669119  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
100669139  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
100669282  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
100669402  IFNLR1; interferon lambda receptor 1 isoform X1 [KO:K05140]
100669515  IL25; interleukin-25 [KO:K05493]
100669544  MSTN; growth/differentiation factor 8 [KO:K05497]
100669556  IL6ST; interleukin-6 receptor subunit beta isoform X2 [KO:K05060]
100669652  GDF6; growth/differentiation factor 6 [KO:K20012]
100669996  [KO:K05136]
100670281  [KO:K04738]
100670325  CXCL12; stromal cell-derived factor 1 [KO:K10031]
100670441  GDF15; growth/differentiation factor 15 [KO:K05504]
100670489  INHA; inhibin alpha chain [KO:K05500]
100670539  [KO:K16622]
100670665  TNFRSF6B; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 6B [KO:K05143]
100670704  CSF1; macrophage colony-stimulating factor 1 isoform X3 [KO:K05453]
100670763  TSLP; LOW QUALITY PROTEIN: thymic stromal lymphopoietin [KO:K05436]
100670804  RELL1; RELT-like protein 1 [KO:K26541]
100670956  CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
100671102  NGFR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16 [KO:K02583]
100671108  CCR4; C-C chemokine receptor type 4 [KO:K04179]
100671266  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
100671328  EBI3; interleukin-27 subunit beta isoform X2 [KO:K24476]
100671359  CCL21; C-C motif chemokine 21 [KO:K16062]
100671392  TGFBR2; TGF-beta receptor type-2 isoform X2 [KO:K04388] [EC:2.7.11.30]
100671397  INHBB; inhibin beta B chain [KO:K22687]
100671503  [KO:K04738]
100671599  CLCF1; LOW QUALITY PROTEIN: cardiotrophin-like cytokine factor 1 [KO:K05421]
100671643  CCL19; C-C motif chemokine 19 [KO:K05512]
100671773  CCL17; C-C motif chemokine 17 [KO:K21083]
100671927  CCL27; LOW QUALITY PROTEIN: C-C motif chemokine 27 [KO:K16598]
100672055  BMP10; bone morphogenetic protein 10 [KO:K22670]
100672064  CCL22; C-C motif chemokine 22 [KO:K21095]
100672132  CCL28; C-C motif chemokine 28 [KO:K05513]
100672143  TNFRSF1A; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 1A [KO:K03158]
100672302  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
100672413  IL11; interleukin-11 [KO:K05417]
100672530  EDA2R; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 27 [KO:K05163]
100672636  CCL5; C-C motif chemokine 5 [KO:K12499]
100672715  LTBR; tumor necrosis factor receptor superfamily member 3 [KO:K03159]
100672726  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
100672839  BMP6; LOW QUALITY PROTEIN: bone morphogenetic protein 6 [KO:K16620]
100672898  IFNAR2; interferon alpha/beta receptor 2 isoform X2 [KO:K05131]
100672999  CD27; CD27 antigen isoform X2 [KO:K05144]
100673105  CCR10; C-C chemokine receptor type 10 [KO:K04185]
100673204  [KO:K12964]
100673493  [KO:K12964]
100673654  CNTFR; ciliary neurotrophic factor receptor subunit alpha [KO:K05059]
100673788  [KO:K12964]
100673830  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
100674106  CCL25; C-C motif chemokine 25 [KO:K13072]
100674484  IL4; interleukin-4 [KO:K05430]
100674711  GDF10; growth/differentiation factor 10 [KO:K22674]
100674746  IL1B; interleukin-1 beta [KO:K04519]
100674770  IL13; interleukin-13 [KO:K05435]
100674796  IL33; interleukin-33 [KO:K12967]
100674816  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
100674920  TNFRSF19; tumor necrosis factor receptor superfamily member 19 [KO:K05155]
100674935  IL1F10; interleukin-1 family member 10 [KO:K05488]
100675000  GDF2; growth/differentiation factor 2 [KO:K05503]
100675007  CD4; LOW QUALITY PROTEIN: T-cell surface glycoprotein CD4 [KO:K06454]
100675032  IL1A; interleukin-1 alpha [KO:K04383]
100675222  [KO:K05481]
100675335  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
100675426  IL17F; interleukin-17F [KO:K05494]
100675489  [KO:K14624]
100675503  [KO:K05484]
100675615  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
100675709  IL17A; interleukin-17A [KO:K05489]
100675774  [KO:K16596]
100675786  [KO:K05487]
100675861  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
100676177  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
100676668  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
100677087  XCL1; lymphotactin [KO:K05507]
100677125  TNF; tumor necrosis factor isoform X2 [KO:K03156]
100677201  CX3CL1; fractalkine isoform X2 [KO:K05508]
100677387  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
100677409  LTA; lymphotoxin-alpha [KO:K05468]
100677416  INHBC; inhibin beta C chain [KO:K22688]
100677702  INHBE; inhibin beta E chain [KO:K22689]
104845437  TNFSF13; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 13 [KO:K05475]
104846102  [KO:K04722]
104846103  [KO:K04722]
104846191  [KO:K05504]
104846264  CXCL1; growth-regulated alpha protein [KO:K05505]
104846292  CCL1; C-C motif chemokine 1 [KO:K05514]
104846894  IL31; interleukin-31 [KO:K22631]
104847204  IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
111749385  [KO:K05066]
111749846  [KO:K16598]
111750521  [KO:K04736]
111751623  [KO:K22628]
111751758  [KO:K05511]
Reference
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
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