KEGG   PATHWAY: rro05168
Entry
rro05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Rhinopithecus roxellana (golden snub-nosed monkey)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
rro05168  Herpes simplex virus 1 infection
rro05168

Organism
Rhinopithecus roxellana (golden snub-nosed monkey) [GN:rro]
Gene
104661912  LTA; lymphotoxin-alpha [KO:K05468]
104665362  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
104664579  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
104669650  TRAF2; TNF receptor-associated factor 2 isoform X2 [KO:K03173] [EC:2.3.2.27]
104669508  TRAF5; TNF receptor-associated factor 5 [KO:K09849]
104666046  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 [KO:K07209] [EC:2.7.11.10]
104656469  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
104667046  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
104679802  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
104662315  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
104664815  RELA; transcription factor p65 [KO:K04735]
104674657  BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
104674658  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X2 [KO:K16060]
104657223  NECTIN1; nectin-1 [KO:K06081]
104673464  NECTIN2; nectin-2 [KO:K06531]
104673605  PILRB; paired immunoglobulin-like type 2 receptor beta isoform X8 [KO:K15411]
104673606  PILRA; paired immunoglobulin-like type 2 receptor alpha isoform X1 [KO:K15411]
104674419  PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X2 [KO:K07293] [EC:3.1.3.48]
104670562  ITGA5; integrin alpha-5 [KO:K06484]
104662513  ITGB3; integrin beta-3 isoform X1 [KO:K06493]
104655840  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
115895854  proto-oncogene tyrosine-protein kinase Src-like [KO:K05704] [EC:2.7.10.2]
104662008  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
104669676  CARD9; caspase recruitment domain-containing protein 9 [KO:K12794]
104667206  IRF3; interferon regulatory factor 3 isoform X2 [KO:K05411]
104670295  IFNB1; interferon beta [KO:K05415]
104661662  TP53; cellular tumor antigen p53 [KO:K04451]
104665361  C3; complement C3 [KO:K03990]
104655862  C5; complement C5 isoform X1 [KO:K03994]
104664594  CFP; properdin [KO:K15412]
104677747  TLR2; toll-like receptor 2 [KO:K10159]
104657448  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
104682894  IRF7; interferon regulatory factor 7 isoform X2 [KO:K09447]
104673812  TLR3; toll-like receptor 3 isoform X2 [KO:K05401]
104665406  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
104677388  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
104662981  IRAK1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
104658364  TRAF6; LOW QUALITY PROTEIN: TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
104657888  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
104682560  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
104676257  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
115899261  LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2-like [KO:K04404]
104672547  IL1B; interleukin-1 beta [KO:K04519]
104679596  CCL5; C-C motif chemokine 5 [KO:K12499]
104675233  IL6; interleukin-6 isoform X1 [KO:K05405]
104661913  TNF; tumor necrosis factor isoform X1 [KO:K03156]
104665012  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
104669104  IL12B; interleukin-12 subunit beta [KO:K05425]
104655060  DDX58; probable ATP-dependent RNA helicase DDX58 [KO:K12646] [EC:5.6.2.6]
104661275  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
104674592  MAVS; mitochondrial antiviral-signaling protein [KO:K12648]
104654431  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
104661734  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
104680828  TBK1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
104670273  interferon alpha-1/13 [KO:K05414]
104670275  IFNA8; interferon alpha-8 [KO:K05414]
104670276  interferon alpha-1/13-like [KO:K05414]
104670278  IFNA6; interferon alpha-6 [KO:K05414]
104670280  interferon alpha-14 [KO:K05414]
104670290  interferon alpha-4 [KO:K05414]
104670292  interferon alpha-10-like [KO:K05414]
104680728  interferon alpha-10 [KO:K05414]
115893964  interferon alpha-4 [KO:K05414]
115893973  interferon alpha-10-like [KO:K05414]
104669277  CGAS; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
104681744  STING1; stimulator of interferon genes protein isoform X1 [KO:K12654]
104675136  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
104664823  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
104668466  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
104665816  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X3 [KO:K16194] [EC:2.7.11.1]
104669977  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
104674177  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [KO:K08860] [EC:2.7.11.1]
104659676  EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
104665027  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
104666328  EIF2B1; translation initiation factor eIF-2B subunit alpha [KO:K03239]
104677583  EIF2B2; translation initiation factor eIF-2B subunit beta [KO:K03754]
104678256  EIF2B3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
104678252  uncharacterized protein LOC104678252 [KO:K03241]
104668490  EIF2B4; translation initiation factor eIF-2B subunit delta isoform X2 [KO:K03680]
104664636  EIF2B5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
104666641  OAS1; 2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
104666642  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
104666645  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
104666789  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
104661167  HCFC1; host cell factor 1 isoform X3 [KO:K14966]
104657472  HCFC2; host cell factor 2 isoform X1 [KO:K27390]
104658824  POU2F2; POU domain, class 2, transcription factor 2 isoform X9 [KO:K09364]
104668980  POU2F1; POU domain, class 2, transcription factor 1 isoform X2 [KO:K09364]
104657225  POU2F3; POU domain, class 2, transcription factor 3 isoform X1 [KO:K09364]
104658750  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
104658748  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
104677022  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
104668074  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
104670479  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
104675282  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
104673676  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
104662694  IRF9; interferon regulatory factor 9 [KO:K04693]
115897716  interferon regulatory factor 9 [KO:K04693]
104682281  ZNF317; zinc finger protein 317 isoform X1 [KO:K09228]
104666129  RBAK; RB-associated KRAB zinc finger protein isoform X1 [KO:K09228]
104680887  ZNF606; zinc finger protein 606 isoform X1 [KO:K09228]
104658403  ZNF81; zinc finger protein 81 [KO:K09228]
104654894  ZFP69B; zinc finger protein 69 homolog B isoform X1 [KO:K09228]
104654897  ZNF684; zinc finger protein 684 isoform X4 [KO:K09228]
104655089  ZNF860; LOW QUALITY PROTEIN: zinc finger protein 860 [KO:K09228]
104654852  ZNF641; zinc finger protein 641 isoform X2 [KO:K09228]
104655592  ZFP90; zinc finger protein 90 homolog isoform X1 [KO:K09228]
104658186  ZNF510; zinc finger protein 510 isoform X1 [KO:K09228]
104656133  ZNF436; zinc finger protein 436 [KO:K09228]
104657267  LOW QUALITY PROTEIN: zinc finger protein 708-like [KO:K09228]
104676213  ZNF879; zinc finger protein 879 isoform X1 [KO:K09228]
104676214  ZNF354C; zinc finger protein 354C isoform X1 [KO:K09228]
104676215  zinc finger protein 454 [KO:K09228]
104676219  ZNF354B; zinc finger protein 354B [KO:K09228]
104676253  ZNF267; zinc finger protein 267 isoform X1 [KO:K09228]
104676125  ZNF780A; zinc finger protein 780A isoform X1 [KO:K09228]
104676127  zinc finger protein 780B isoform X1 [KO:K09228]
104676128  ZNF546; zinc finger protein 546 isoform X2 [KO:K09228]
104659567  ZNF302; zinc finger protein 302 isoform X2 [KO:K09228]
104659613  ZNF286A; zinc finger protein 286A isoform X3 [KO:K09228]
104676522  ZNF630; zinc finger protein 630 isoform X1 [KO:K09228]
104675958  ZNF248; zinc finger protein 248 isoform X2 [KO:K09228]
104675962  zinc finger protein 25 isoform X1 [KO:K09228]
104676035  ZNF331; zinc finger protein 331 isoform X3 [KO:K09228]
104676038  zinc finger protein 845-like [KO:K09228]
104676040  zinc finger protein 761 isoform X2 [KO:K09228]
104676042  zinc finger protein 761-like isoform X1 [KO:K09228]
104676769  ZFP57; zinc finger protein 57 homolog [KO:K09228]
104677118  ZNF195; zinc finger protein 195 isoform X2 [KO:K09228]
104679797  ZNF623; zinc finger protein 623 [KO:K09228]
104679913  ZNF529; zinc finger protein 529 isoform X2 [KO:K09228]
104679914  ZNF382; zinc finger protein 382 isoform X2 [KO:K09228]
104679915  ZNF461; zinc finger protein 461 isoform X1 [KO:K09228]
104679918  ZNF567; zinc finger protein 567 isoform X2 [KO:K09228]
104679919  ZNF850; zinc finger protein 850 [KO:K09228]
104679922  ZNF527; zinc finger protein 527 isoform X1 [KO:K09228]
104679923  ZNF875; zinc finger protein 875 isoform X1 [KO:K09228]
104679924  ZNF383; zinc finger protein 383 [KO:K09228]
104679926  ZNF585A; zinc finger protein 585A [KO:K09228]
104679928  ZNF420; zinc finger protein 420 isoform X1 [KO:K09228]
104679929  zinc finger protein 568 [KO:K09228]
104679930  ZNF829; zinc finger protein 829 [KO:K09228]
104679933  ZNF790; zinc finger protein 790 isoform X1 [KO:K09228]
104679937  ZNF570; zinc finger protein 570 isoform X4 [KO:K09228]
104679939  ZNF540; zinc finger protein 540 isoform X2 [KO:K09228]
104679946  ZNF607; zinc finger protein 607 isoform X2 [KO:K09228]
104679359  zinc finger protein 107 isoform X2 [KO:K09228]
104679414  zinc finger protein 273 [KO:K09228]
104679493  ZNF557; zinc finger protein 557 isoform X2 [KO:K09228]
104662636  zinc finger protein 257-like isoform X1 [KO:K09228]
104661482  zinc finger protein 501-like isoform X2 [KO:K09228]
104661536  ZNF764; zinc finger protein 764 isoform X1 [KO:K09228]
104661537  ZNF688; zinc finger protein 688 isoform X1 [KO:K09228]
104661539  ZNF785; LOW QUALITY PROTEIN: zinc finger protein 785 [KO:K09228]
104661540  ZNF689; zinc finger protein 689 [KO:K09228]
104661035  ZNF333; zinc finger protein 333 isoform X1 [KO:K09228]
104664001  ZNF430; zinc finger protein 430 isoform X1 [KO:K09228]
104664003  ZNF85; zinc finger protein 85 isoform X1 [KO:K09228]
104664007  LOW QUALITY PROTEIN: putative zinc finger protein 66 [KO:K09228]
104664589  ZNF157; zinc finger protein 157 [KO:K09228]
104664590  ZNF41; zinc finger protein 41 isoform X3 [KO:K09228]
104660984  ZNF337; zinc finger protein 337 isoform X1 [KO:K09228]
104661103  ZNF791; zinc finger protein 791 [KO:K09228]
104663447  ZNF214; zinc finger protein 214 isoform X1 [KO:K09228]
104659864  ZNF620; zinc finger protein 620 [KO:K09228]
104659865  ZNF621; zinc finger protein 621 isoform X2 [KO:K09228]
104661107  ZNF136; zinc finger protein 136 isoform X1 [KO:K09228]
104661111  zinc finger protein 20 isoform X2 [KO:K09228]
104661113  ZNF433; zinc finger protein 433 isoform X1 [KO:K09228]
104661114  ZNF700; zinc finger protein 700 isoform X1 [KO:K09228]
104661116  LOW QUALITY PROTEIN: zinc finger protein 440 [KO:K09228]
104661119  ZNF627; zinc finger protein 627 isoform X2 [KO:K09228]
104661152  zinc finger protein 878 [KO:K09228]
104661155  zinc finger protein 627-like [KO:K09228]
104661190  ZFP92; zinc finger protein 92 homolog [KO:K09228]
104661104  ZNF564; zinc finger protein 564 [KO:K09228]
104661437  zinc finger protein 736 [KO:K09228]
104661440  putative zinc finger protein 735 [KO:K09228]
104661443  ZNF514; zinc finger protein 514 isoform X1 [KO:K09228]
104661444  ZNF2; zinc finger protein 2 [KO:K09228]
104661105  ZNF563; zinc finger protein 563 isoform X2 [KO:K09228]
104661106  zinc finger protein 44 isoform X1 [KO:K09228]
104662189  ZNF596; zinc finger protein 596 isoform X2 [KO:K09228]
104662907  ZNF778; LOW QUALITY PROTEIN: zinc finger protein 778 [KO:K09228]
104678806  ZNF334; zinc finger protein 334 isoform X4 [KO:K09228]
104677836  ZFP1; zinc finger protein 1 homolog isoform X1 [KO:K09228]
104671711  ZNF721; LOW QUALITY PROTEIN: zinc finger protein 721 [KO:K09228]
104672666  zinc finger protein 28-like [KO:K09228]
104672668  zinc finger protein 611 [KO:K09228]
104672670  zinc finger protein 611 [KO:K09228]
104672675  ZNF83; zinc finger protein 83 isoform X1 [KO:K09228]
104672679  ZNF528; zinc finger protein 528 isoform X1 [KO:K09228]
104672682  ZNF610; zinc finger protein 610 isoform X2 [KO:K09228]
104672683  ZNF480; zinc finger protein 480 [KO:K09228]
104672687  ZNF616; zinc finger protein 616 isoform X2 [KO:K09228]
104672690  ZNF841; zinc finger protein 841 isoform X1 [KO:K09228]
104672691  ZNF432; zinc finger protein 432 [KO:K09228]
104672692  ZNF614; zinc finger protein 614 [KO:K09228]
104672693  ZNF615; zinc finger protein 615 [KO:K09228]
104672694  ZNF350; zinc finger protein 350 [KO:K09228]
104672695  ZNF613; zinc finger protein 613 [KO:K09228]
104672696  ZNF577; zinc finger protein 577 isoform X2 [KO:K09228]
104672705  ZNF175; zinc finger protein 175 isoform X1 [KO:K09228]
104672969  LOW QUALITY PROTEIN: zinc finger protein 737-like [KO:K09228]
104680870  LOW QUALITY PROTEIN: zinc finger protein 324A [KO:K09228]
104680871  ZNF324B; zinc finger protein 324B [KO:K09228]
104681611  ZNF747; KRAB domain-containing protein ZNF747 isoform X2 [KO:K09228]
104681620  ZNF768; zinc finger protein 768 [KO:K09228]
104682278  ZNF558; zinc finger protein 558 isoform X1 [KO:K09228]
104682287  ZNF699; zinc finger protein 699 isoform X1 [KO:K09228]
104680036  LOW QUALITY PROTEIN: zinc finger protein 658-like [KO:K09228]
115893967  ZNF484; zinc finger protein 484 isoform X1 [KO:K09228]
104680896  ZNF154; zinc finger protein 154 isoform X1 [KO:K09228]
104680897  ZNF551; zinc finger protein 551 isoform X1 [KO:K09228]
104680901  ZNF211; zinc finger protein 211 isoform X1 [KO:K09228]
104680903  ZNF530; zinc finger protein 530 isoform X1 [KO:K09228]
104680904  ZIK1; zinc finger protein interacting with ribonucleoprotein K isoform X1 [KO:K09228]
104680906  ZNF416; zinc finger protein 416 isoform X1 [KO:K09228]
104680907  ZNF550; zinc finger protein 550 [KO:K09228]
104680908  ZNF549; zinc finger protein 549 [KO:K09228]
104680912  zinc finger protein 17 isoform X1 [KO:K09228]
104680913  ZNF548; zinc finger protein 548 [KO:K09228]
104680916  ZNF547; zinc finger protein 547 isoform X2 [KO:K09228]
104680917  ZNF543; zinc finger protein 543 isoform X1 [KO:K09228]
104680918  ZNF304; zinc finger protein 304 [KO:K09228]
104680919  ZNF460; LOW QUALITY PROTEIN: zinc finger protein 460 [KO:K09228]
104680921  ZNF264; zinc finger protein 264 isoform X1 [KO:K09228]
104680939  ZNF582; zinc finger protein 582 isoform X1 [KO:K09228]
104680940  putative zinc finger protein 542 [KO:K09228]
104680923  ZIM3; zinc finger imprinted 3 [KO:K09228]
104680931  ZFP28; zinc finger protein 28 homolog [KO:K09228]
104680932  ZNF470; zinc finger protein 470 [KO:K09228]
104680935  ZNF471; zinc finger protein 471 isoform X2 [KO:K09228]
104680937  ZNF583; zinc finger protein 583 isoform X2 [KO:K09228]
104680938  ZNF667; zinc finger protein 667 isoform X1 [KO:K09228]
115892378  LOW QUALITY PROTEIN: zinc finger protein 729-like [KO:K09228]
104663107  zinc finger protein 492-like [KO:K09228]
115892381  zinc finger protein 566-like isoform X1 [KO:K09228]
115892698  LOW QUALITY PROTEIN: zinc finger protein 718-like [KO:K09228]
104670500  ZNF846; zinc finger protein 846 isoform X5 [KO:K09228]
104669903  zinc finger protein 141 isoform X1 [KO:K09228]
104673656  zinc finger protein 595 isoform X1 [KO:K09228]
104676220  ZNF354A; zinc finger protein 354A isoform X1 [KO:K09228]
104653868  zinc finger protein 91-like [KO:K09228]
104670976  ZNF184; zinc finger protein 184 isoform X1 [KO:K09228]
104673195  zinc finger protein OZF-like [KO:K09228]
104666686  ZNF565; zinc finger protein 565 isoform X3 [KO:K09228]
104666689  ZFP14; zinc finger protein 14 homolog isoform X2 [KO:K09228]
104666690  ZFP82; zinc finger protein 82 homolog isoform X2 [KO:K09228]
104667123  ZNF792; zinc finger protein 792 isoform X3 [KO:K09228]
104667129  ZNF599; zinc finger protein 599 [KO:K09228]
104667130  ZNF181; zinc finger protein 181 isoform X2 [KO:K09228]
104673591  ZNF3; zinc finger protein 3 isoform X2 [KO:K09228]
104673273  ZNF311; zinc finger protein 311 isoform X1 [KO:K09228]
104673473  ZNF180; zinc finger protein 180 isoform X1 [KO:K09228]
104673475  ZNF229; zinc finger protein 229 [KO:K09228]
104673476  ZNF285; zinc finger protein 285 isoform X1 [KO:K09228]
104669575  LOW QUALITY PROTEIN: zinc finger protein 100-like [KO:K09228]
104669470  ZNF283; zinc finger protein 283 isoform X2 [KO:K09228]
104669471  ZNF404; LOW QUALITY PROTEIN: zinc finger protein 404 [KO:K09228]
104669472  ZNF45; zinc finger protein 45 isoform X1 [KO:K09228]
104669473  ZNF221; zinc finger protein 221 [KO:K09228]
104669474  ZNF230; zinc finger protein 230 [KO:K09228]
104669476  ZNF155; zinc finger protein 155 isoform X1 [KO:K09228]
104669477  ZNF222; zinc finger protein 222 [KO:K09228]
104669479  ZNF284; zinc finger protein 284 [KO:K09228]
104669481  ZNF224; zinc finger protein 224 isoform X2 [KO:K09228]
104669482  ZNF225; zinc finger protein 225 [KO:K09228]
104669483  ZNF234; zinc finger protein 234 isoform X1 [KO:K09228]
104669485  ZNF226; zinc finger protein 226 [KO:K09228]
104669487  ZNF227; zinc finger protein 227 [KO:K09228]
104669488  ZNF235; zinc finger protein 235 isoform X1 [KO:K09228]
104669489  ZNF112; zinc finger protein 112 [KO:K09228]
104675895  zinc finger protein 713 isoform X1 [KO:K09228]
104665461  ZNF77; zinc finger protein 77 isoform X1 [KO:K09228]
104665463  ZNF555; zinc finger protein 555 isoform X1 [KO:K09228]
104665464  ZNF554; zinc finger protein 554 isoform X2 [KO:K09228]
104665829  ZNF12; zinc finger protein 12 [KO:K09228]
104666864  ZNF74; zinc finger protein 74 isoform X2 [KO:K09228]
104667221  ZNF473; zinc finger protein 473 isoform X1 [KO:K09228]
104669540  ZNF680; zinc finger protein 680 isoform X1 [KO:K09228]
104669310  LOW QUALITY PROTEIN: zinc finger protein 208 [KO:K09228]
104680885  ZNF135; zinc finger protein 135 isoform X1 [KO:K09228]
115892145  zinc finger protein 253 isoform X1 [KO:K09228]
104680390  ZNF682; zinc finger protein 682 isoform X1 [KO:K09228]
104679144  zinc finger protein 93 [KO:K09228]
104669300  LOW QUALITY PROTEIN: zinc finger protein 729 [KO:K09228]
104669315  zinc finger protein 429 [KO:K09228]
104669305  LOW QUALITY PROTEIN: zinc finger protein 100-like [KO:K09228]
104657295  LOW QUALITY PROTEIN: zinc finger protein 431 [KO:K09228]
115892068  zinc finger protein 98 isoform X1 [KO:K09228]
115892070  zinc finger protein 492-like [KO:K09228]
104680880  ZNF544; zinc finger protein 544 [KO:K09228]
104654760  ZNF23; zinc finger protein 23 isoform X1 [KO:K09228]
104680955  ZNF132; zinc finger protein 132 [KO:K09228]
104680959  ZNF814; zinc finger protein 814 [KO:K09228]
104680665  ZNF101; zinc finger protein 101 isoform X1 [KO:K09228]
104680666  ZNF14; zinc finger protein 14 isoform X2 [KO:K09228]
104681123  ZNF124; zinc finger protein 124 isoform X1 [KO:K09228]
104681125  ZNF670; zinc finger protein 670 isoform X3 [KO:K09228]
104681429  ZNF624; zinc finger protein 624 [KO:K09228]
104674313  ZNF605; zinc finger protein 605 isoform X1 [KO:K09228]
104674314  ZNF84; zinc finger protein 84 [KO:K09228]
104674317  ZNF891; zinc finger protein 891 isoform X2 [KO:K09228]
104674318  ZNF268; zinc finger protein 268 isoform X1 [KO:K09228]
104674319  ZNF10; zinc finger protein 10 isoform X1 [KO:K09228]
104667863  ZFP37; zinc finger protein 37 homolog isoform X1 [KO:K09228]
104667898  zinc finger protein 675 [KO:K09228]
104667580  ZNF658; zinc finger protein 658 [KO:K09228]
104680895  ZNF671; zinc finger protein 671 isoform X1 [KO:K09228]
115892929  LOW QUALITY PROTEIN: zinc finger protein 133-like [KO:K09228]
104681000  zinc finger protein 133 isoform X1 [KO:K09228]
104682125  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
104680872  ZNF584; zinc finger protein 584 isoform X1 [KO:K09228]
104680879  ZNF8; zinc finger protein 8 [KO:K09228]
104680890  ZNF256; zinc finger protein 256 [KO:K09228]
104680892  ZNF552; zinc finger protein 552 [KO:K09228]
104659884  ZNF782; zinc finger protein 782 isoform X1 [KO:K09228]
104679798  ZNF707; zinc finger protein 707 isoform X1 [KO:K09228]
104670439  ZNF300; zinc finger protein 300 isoform X1 [KO:K09228]
104674630  ZNF343; zinc finger protein 343 isoform X1 [KO:K09228]
104670503  zinc finger protein 561 isoform X1 [KO:K09228]
104670505  ZNF426; zinc finger protein 426 isoform X1 [KO:K09228]
104670502  ZNF562; zinc finger protein 562 [KO:K09228]
104670799  ZNF189; zinc finger protein 189 isoform X1 [KO:K09228]
104671605  ZNF169; zinc finger protein 169 isoform X1 [KO:K09228]
104671643  LOW QUALITY PROTEIN: zinc finger protein 252-like [KO:K09228]
104671647  ZNF250; zinc finger protein 250 isoform X2 [KO:K09228]
104671649  zinc finger protein 7 isoform X11 [KO:K09228]
104671651  ZNF517; zinc finger protein 517 isoform X2 [KO:K09228]
104671653  ZNF34; zinc finger protein 34 isoform X1 [KO:K09228]
104671654  ZNF251; zinc finger protein 251 isoform X1 [KO:K09228]
104672298  ZNF597; zinc finger protein 597 isoform X1 [KO:K09228]
104672300  ZSCAN32; zinc finger and SCAN domain-containing protein 32 [KO:K09228]
104672306  ZNF200; zinc finger protein 200 [KO:K09228]
104672312  ZNF205; zinc finger protein 205 isoform X1 [KO:K09228]
104672651  ZNF677; zinc finger protein 677 isoform X1 [KO:K09228]
104672655  ZNF347; zinc finger protein 347 isoform X3 [KO:K09228]
104672656  ZNF415; zinc finger protein 415 isoform X3 [KO:K09228]
104672657  ZNF160; zinc finger protein 160 isoform X1 [KO:K09228]
104672660  zinc finger protein 888-like [KO:K09228]
104672662  zinc finger protein 816 isoform X2 [KO:K09228]
104672663  zinc finger protein 320 [KO:K09228]
104672664  zinc finger protein 468 isoform X1 [KO:K09228]
104679936  ZNF569; zinc finger protein 569 isoform X1 [KO:K09228]
104660954  zinc finger protein 254 isoform X1 [KO:K09228]
104671910  LOW QUALITY PROTEIN: zinc finger protein 676-like [KO:K09228]
104666718  ZNF724; zinc finger protein 724 isoform X1 [KO:K09228]
115892354  LOW QUALITY PROTEIN: zinc finger protein 676-like [KO:K09228]
104679938  ZNF571; zinc finger protein 571 [KO:K09228]
104670511  ZNF559; zinc finger protein 559 [KO:K09228]
104670527  ZNF560; zinc finger protein 560 [KO:K09228]
104665887  ZNF79; LOW QUALITY PROTEIN: zinc finger protein 79 [KO:K09228]
104667004  protein ZNF783 isoform X1 [KO:K09228]
104667006  ZNF212; zinc finger protein 212 isoform X4 [KO:K09228]
104667007  ZNF398; zinc finger protein 398 [KO:K09228]
104667008  ZNF425; zinc finger protein 425 [KO:K09228]
104667009  ZNF786; zinc finger protein 786 [KO:K09228]
104665833  ZNF316; zinc finger protein 316 isoform X1 [KO:K09228]
104665832  ZNF853; zinc finger protein 853 isoform X1 [KO:K09228]
104661154  ZNF823; zinc finger protein 823 [KO:K09228]
104669478  zinc finger protein 223 isoform X1 [KO:K09228]
104654895  ZFP69; zinc finger protein 69 homolog isoform X1 [KO:K09228]
115900666  zinc finger protein 566 isoform X1 [KO:K09228]
104680963  ZNF805; zinc finger protein 805 isoform X1 [KO:K09228]
104672697  ZNF649; zinc finger protein 649 isoform X1 [KO:K09228]
104680668  zinc finger protein 506 [KO:K09228]
104672631  ZNF674; zinc finger protein 674 isoform X1 [KO:K09228]
104671344  ZNF589; LOW QUALITY PROTEIN: zinc finger protein 589 [KO:K09228]
115899190  zinc finger protein 799 isoform X1 [KO:K09228]
115892018  ZNF442; zinc finger protein 442 isoform X1 [KO:K09228]
115899197  ZNF556; zinc finger protein 556 [KO:K09228]
104661146  ZNF709; zinc finger protein 709 isoform X1 [KO:K09228]
104661144  ZNF490; zinc finger protein 490 isoform X1 [KO:K09228]
104661150  zinc finger protein 433-like [KO:K09228]
104667002  zinc finger protein 746 isoform X1 [KO:K09228]
104670512  zinc finger protein 177 [KO:K09228]
115891995  ZNF25; zinc finger protein 25 [KO:K09228]
104661198  ZNF275; zinc finger protein 275 isoform X1 [KO:K09228]
104665462  ZNF57; zinc finger protein 57 isoform X1 [KO:K09228]
104675969  ZNF37A; zinc finger protein 37A isoform X1 [KO:K09228]
115900440  zinc finger protein 33A [KO:K09228]
104659866  ZNF619; LOW QUALITY PROTEIN: zinc finger protein 619 [KO:K09228]
104681124  ZNF669; LOW QUALITY PROTEIN: zinc finger protein 669 [KO:K09228]
104674329  ZNF26; zinc finger protein 26 isoform X1 [KO:K09228]
115898280  LOW QUALITY PROTEIN: zinc finger protein 679-like [KO:K09228]
104661436  zinc finger protein 679 [KO:K09228]
104666403  putative zinc finger protein 735 [KO:K09228]
104680503  LOW QUALITY PROTEIN: zinc finger protein 484 [KO:K09228]
104667275  zinc finger protein 883 [KO:K09228]
104676054  zinc finger protein 845 [KO:K09228]
104672714  zinc finger protein 665-like isoform X1 [KO:K09228]
104676046  zinc finger protein 816-like isoform X1 [KO:K09228]
104672673  LOW QUALITY PROTEIN: zinc finger protein 813 [KO:K09228]
104676053  zinc finger protein 813 isoform X1 [KO:K09228]
104672684  ZNF766; zinc finger protein 766 isoform X1 [KO:K09228]
104672677  LOW QUALITY PROTEIN: zinc finger protein 701-like [KO:K09228]
104680891  ZNF587; zinc finger protein 587 isoform X1 [KO:K09228]
104675532  zinc finger protein 486-like [KO:K09228]
104669314  LOW QUALITY PROTEIN: zinc finger protein 100-like [KO:K09228]
104661149  ZNF788P; putative KRAB domain-containing protein ZNF788 [KO:K09228]
104674315  ZNF140; zinc finger protein 140 isoform X1 [KO:K09228]
104664164  LOW QUALITY PROTEIN: zinc finger protein 705A-like [KO:K09228]
104660369  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
104669486  ZNF233; LOW QUALITY PROTEIN: zinc finger protein 233 [KO:K09228]
104680910  ZNF419; zinc finger protein 419 isoform X1 [KO:K09228]
104680911  ZNF772; zinc finger protein 772 isoform X1 [KO:K09228]
104677759  zinc finger protein 93-like [KO:K09228]
115900785  LOW QUALITY PROTEIN: zinc finger protein 492-like [KO:K09228]
104673841  zinc finger protein 98-like [KO:K09228]
104666575  ZNF114; zinc finger protein 114 [KO:K09228]
104679941  ZFP30; zinc finger protein 30 homolog isoform X1 [KO:K09228]
104679925  ZNF585B; zinc finger protein 585B [KO:K09228]
104667894  zinc finger protein 726 [KO:K09228]
104662184  LOW QUALITY PROTEIN: zinc finger protein 91-like [KO:K09228]
104662638  LOW QUALITY PROTEIN: zinc finger protein 728-like [KO:K09228]
104666725  LOW QUALITY PROTEIN: zinc finger protein 254-like [KO:K09228]
115900746  zinc finger protein 91-like [KO:K09228]
104672654  zinc finger protein 665 [KO:K09228]
104676044  zinc finger protein 813-like [KO:K09228]
104680958  zinc finger protein 587 [KO:K09228]
104680957  ZNF418; zinc finger protein 418 [KO:K09228]
115900735  LOW QUALITY PROTEIN: zinc finger protein 99-like [KO:K09228]
115900736  zinc finger protein 723-like [KO:K09228]
115900740  LOW QUALITY PROTEIN: zinc finger protein 729-like [KO:K09228]
104658401  ZNF182; zinc finger protein 182 isoform X1 [KO:K09228]
115899170  LOW QUALITY PROTEIN: zinc finger protein 333-like [KO:K09228]
104667001  ZNF777; zinc finger protein 777 isoform X1 [KO:K09228]
104667019  ZNF282; zinc finger protein 282 [KO:K09228]
104654758  ZNF19; zinc finger protein 19 isoform X1 [KO:K09228]
104669905  ZNF732; zinc finger protein 732 [KO:K09228]
104670978  ZNF502; zinc finger protein 502 [KO:K09228]
104673649  ZNF92; zinc finger protein 92 isoform X1 [KO:K09228]
104665353  zinc finger protein 708 [KO:K09228]
104667896  zinc finger protein 681 isoform X1 [KO:K09228]
104664005  LOW QUALITY PROTEIN: zinc finger protein 626-like [KO:K09228]
104661110  ZNF625; zinc finger protein 625 [KO:K09228]
104661115  zinc finger protein 69 isoform X1 [KO:K09228]
104661117  ZNF441; LOW QUALITY PROTEIN: zinc finger protein 441 [KO:K09228]
104657308  ZNF738; protein ZNF738 isoform X1 [KO:K09228]
104680874  ZNF497; LOW QUALITY PROTEIN: zinc finger protein 497 [KO:K09228]
104670509  ZNF266; zinc finger protein 266 isoform X1 [KO:K09228]
104672665  zinc finger protein 28 [KO:K09228]
104679943  ZNF573; zinc finger protein 573 [KO:K09228]
104680894  ZNF776; zinc finger protein 776 isoform X1 [KO:K09228]
104681121  zinc finger protein 682-like isoform X1 [KO:K09228]
104677139  ZNF678; zinc finger protein 678 isoform X1 [KO:K09228]
104672676  zinc finger protein 611-like isoform X1 [KO:K09228]
104672728  LOW QUALITY PROTEIN: zinc finger protein 808 [KO:K09228]
104672661  zinc finger protein 888 [KO:K09228]
104672681  ZNF880; zinc finger protein 880 [KO:K09228]
115900722  LOW QUALITY PROTEIN: zinc finger protein 728-like [KO:K09228]
104679390  LOW QUALITY PROTEIN: zinc finger protein 117-like [KO:K09228]
104672354  ZNF485; LOW QUALITY PROTEIN: zinc finger protein 485 [KO:K09228]
104680893  ZNF586; zinc finger protein 586 isoform X1 [KO:K09228]
104660973  BST2; bone marrow stromal antigen 2 [KO:K06731]
104664085  IFNG; interferon gamma [KO:K04687]
104675021  IFNGR1; interferon gamma receptor 1 [KO:K05132]
104658778  IFNGR2; interferon gamma receptor 2 isoform X1 [KO:K05133]
104665700  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
104657969  DAXX; death domain-associated protein 6 isoform X1 [KO:K02308]
104656168  SP100; nuclear autoantigen Sp-100 isoform X1 [KO:K15413]
104678056  protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
115897517  LOW QUALITY PROTEIN: protein PML-like [KO:K10054] [EC:2.3.2.-]
115897528  LOW QUALITY PROTEIN: protein PML-like [KO:K10054] [EC:2.3.2.-]
115891998  protein PML-like [KO:K10054] [EC:2.3.2.-]
104666626  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
104666628  TAP2; antigen peptide transporter 2 isoform X1 [KO:K05654] [EC:7.4.2.14]
104657970  TAPBP; tapasin isoform X2 [KO:K08058]
104679628  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
104661079  CALR; calreticulin isoform X1 [KO:K08057]
104667845  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
104670209  patr class I histocompatibility antigen, B-2 alpha chain isoform X1 [KO:K06751]
104668193  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-42 alpha chain-like [KO:K06751]
104674706  LOW QUALITY PROTEIN: class I histocompatibility antigen, Gogo-B*0101 alpha chain-like [KO:K06751]
104661905  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
115897009  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
104676771  mamu class I histocompatibility antigen, alpha chain F [KO:K06751]
104678084  HLA class I histocompatibility antigen, B-38 alpha chain-like [KO:K06751]
104668434  HLA class I histocompatibility antigen, A-30 alpha chain isoform X1 [KO:K06751]
104677089  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like isoform X1 [KO:K06751]
104673193  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-14 alpha chain [KO:K06751]
104676774  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like [KO:K06751]
104666183  popy class I histocompatibility antigen, alpha chain E isoform X1 [KO:K06751]
104678248  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-67 alpha chain [KO:K06751]
104679609  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
104657986  HLA class II histocompatibility antigen, DP beta 1 chain [KO:K06752]
104657985  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
104673877  HLA class II histocompatibility antigen, DRB1-1 beta chain [KO:K06752]
104673884  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
104673840  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
104673850  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
104673860  HLA class II histocompatibility antigen, DQ alpha 1 chain [KO:K06752]
104673868  HLA class II histocompatibility antigen, DRB1-10 beta chain [KO:K06752]
104666619  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
104666621  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
104666623  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
104670416  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
104663050  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
104665061  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
104670605  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
104662124  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
104675620  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
104680672  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
104673041  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104676121  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
104654186  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
115893905  RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
104669743  TSC1; hamartin isoform X2 [KO:K07206]
104681538  TSC2; tuberin isoform X1 [KO:K07207]
104678707  RHEB; GTP-binding protein Rheb [KO:K07208]
104654362  MTOR; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
104679650  EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
104682865  SRPK1; SRSF protein kinase 1 isoform X1 [KO:K15409] [EC:2.7.11.1]
104669818  SRSF1; serine/arginine-rich splicing factor 1 [KO:K12890]
104658616  serine/arginine-rich splicing factor 8-like [KO:K12891]
104658617  serine/arginine-rich splicing factor 8 [KO:K12891]
104681260  SRSF2; serine/arginine-rich splicing factor 2 [KO:K12891]
104682878  SRSF3; serine/arginine-rich splicing factor 3 [KO:K12892]
104659643  SRSF5; serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
104675686  SRSF4; serine/arginine-rich splicing factor 4 [KO:K12893]
104678890  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 6 [KO:K12893]
115892771  SRSF6; serine/arginine-rich splicing factor 6 [KO:K12893]
115892788  serine/arginine-rich splicing factor 6 [KO:K12893]
104663017  SRSF7; serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
104666255  SRSF9; serine/arginine-rich splicing factor 9 [KO:K21123]
104664213  nuclear RNA export factor 2-like [KO:K14284]
104679330  NXF1; nuclear RNA export factor 1 [KO:K14284]
104678266  NXF3; nuclear RNA export factor 3 [KO:K14284]
104657745  nuclear RNA export factor 2 [KO:K14284]
115898698  LOW QUALITY PROTEIN: nuclear RNA export factor 2-like [KO:K14284]
104655016  ALYREF; THO complex subunit 4 [KO:K12881]
104669600  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
104675147  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
104680127  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
104655653  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2 [KO:K03171]
104677132  FADD; FAS-associated death domain protein [KO:K02373]
104671864  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
104676299  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
104666540  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
104658958  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
104673141  BAD; bcl2-associated agonist of cell death [KO:K02158]
104682248  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
104653720  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
104661761  cytochrome c-like [KO:K08738]
104679886  cytochrome c [KO:K08738]
104672188  cytochrome c [KO:K08738]
104681924  cytochrome c-like [KO:K08738]
115898126  cytochrome c-like [KO:K08738]
115894533  cytochrome c-like [KO:K08738]
115893266  cytochrome c-like [KO:K08738]
115893541  cytochrome c-like [KO:K08738]
115899152  cytochrome c-like [KO:K08738]
104656342  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
104677696  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
104666783  caspase-3-like [KO:K02187] [EC:3.4.22.56]
104673791  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
  Journal
Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
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J Virol 91:e00295-17 (2017)
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Related
pathway
rro03040  Spliceosome
rro03050  Proteasome
rro04115  p53 signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04210  Apoptosis
rro04610  Complement and coagulation cascades
rro04612  Antigen processing and presentation
rro04620  Toll-like receptor signaling pathway
rro04622  RIG-I-like receptor signaling pathway
rro04630  JAK-STAT signaling pathway
KO pathway
ko05168   
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