KEGG   PATHWAY: pleu04519
Entry
pleu04519                   Pathway                                
Name
Cadherin signaling - Peromyscus leucopus (white-footed mouse)
Description
Cadherins constitute a large superfamily of calcium-dependent cell-cell adhesion proteins that serve as critical determinants of the timing and specificity of cell interactions, migration, and morphogenetic processes. Many cadherins mediate mechanical coupling between adjacent cells by organizing highly ordered junctional complexes. Beyond their adhesive roles, cadherins act as signaling platforms that influence cell motility, proliferation, and gene expression.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
pleu04519  Cadherin signaling
pleu04519

Organism
Peromyscus leucopus (white-footed mouse) [GN:pleu]
Gene
114680598  Actg1; LOW QUALITY PROTEIN: actin, cytoplasmic 2 [KO:K05692]
114680645  Rac3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
114680660  Pcdh11x; protocadherin-11 X-linked isoform X1 [KO:K16498]
114681270  Ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
114681319  Wnt7a; protein Wnt-7a [KO:K00572]
114681320  Myo1h; unconventional myosin-Ih [KO:K10356]
114681341  Fgfr1; fibroblast growth factor receptor 1 isoform X4 [KO:K04362] [EC:2.7.10.1]
114681429  Arhgap35; rho GTPase-activating protein 35 [KO:K05732]
114681455  Cdh19; cadherin-19 isoform X1 [KO:K06806]
114681497  Flt4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
114681520  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
114681536  Prickle2; prickle-like protein 2 isoform X1 [KO:K04511]
114681591  Tcf7l1; transcription factor 7-like 1 isoform X1 [KO:K04490]
114681660  Psenen; gamma-secretase subunit PEN-2 [KO:K06170]
114681872  Fat4; protocadherin Fat 4 [KO:K16669]
114682099  Rela; transcription factor p65 [KO:K04735]
114682377  Aph1a; gamma-secretase subunit APH-1A [KO:K06172]
114682488  Abi2; abl interactor 2 isoform X1 [KO:K05751]
114682497  Scn5a; LOW QUALITY PROTEIN: sodium channel protein type 5 subunit alpha [KO:K04838]
114682732  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
114682779  Arpc5l; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
114682816  Lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
114682946  Dchs2; LOW QUALITY PROTEIN: protocadherin-23 [KO:K16507]
114682971  Wnt3a; protein Wnt-3a [KO:K00312]
114683006  Wnt9a; protein Wnt-9a [KO:K01064]
114683055  Tcf7; transcription factor 7 isoform X2 [KO:K02620]
114683107  Cdh26; LOW QUALITY PROTEIN: cadherin-like protein 26 [KO:K22658]
114683205  Nfkb1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
114683276  Map2k3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
114683308  Dvl3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
114683430  Cdh3; cadherin-3 isoform X1 [KO:K06796]
114683440  [KO:K05689]
114683507  Kdr; vascular endothelial growth factor receptor 2 [KO:K05098] [EC:2.7.10.1]
114683759  Pdgfra; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
114683810  Dchs1; LOW QUALITY PROTEIN: protocadherin-16 [KO:K16507]
114683949  Daam1; disheveled-associated activator of morphogenesis 1 isoform X1 [KO:K04512]
114683953  [KO:K06269] [EC:3.1.3.16]
114684081  Apc2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085]
114684143  Sav1; protein salvador homolog 1 isoform X1 [KO:K16686]
114684216  Vav2; guanine nucleotide exchange factor VAV2 isoform X4 [KO:K05730]
114684256  [KO:K05692]
114684426  Enah; protein enabled homolog isoform X1 [KO:K05746]
114684440  Cdh7; LOW QUALITY PROTEIN: cadherin-7 [KO:K06799]
114684682  Actn4; alpha-actinin-4 isoform X3 [KO:K05699]
114685002  Amotl1; angiomotin-like protein 1 isoform X2 [KO:K06104]
114685127  [KO:K02833]
114685321  Myo1f; unconventional myosin-If [KO:K10356]
114685381  Tmie; transmembrane inner ear expressed protein isoform X2 [KO:K23907]
114685753  Fzd7; frizzled-7 [KO:K02432]
114685987  Ppp1ca; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
114686016  Fzd9; frizzled-9 [KO:K02842]
114686155  [KO:K16493]
114686156  [KO:K16493]
114686158  [KO:K16493]
114686160  [KO:K16493]
114686161  [KO:K16493]
114686163  [KO:K16494]
114686164  [KO:K16494]
114686165  [KO:K16494]
114686166  [KO:K16494]
114686168  [KO:K16493]
114686171  [KO:K16493]
114686172  [KO:K16494]
114686173  Pcdhb2; LOW QUALITY PROTEIN: protocadherin beta-2 [KO:K16494]
114686174  [KO:K16494]
114686176  [KO:K16494]
114686177  [KO:K16494]
114686182  [KO:K16494]
114686184  [KO:K16494]
114686185  [KO:K16494]
114686186  Pcdhb1; LOW QUALITY PROTEIN: protocadherin beta-1 [KO:K16494]
114686187  [KO:K16494]
114686321  Lats1; serine/threonine-protein kinase LATS1 isoform X1 [KO:K08791] [EC:2.7.11.1]
114686543  Vav1; proto-oncogene vav [KO:K05730]
114687010  Gabra4; gamma-aminobutyric acid receptor subunit alpha-4 isoform X1 [KO:K05175]
114687119  [KO:K16495]
114687120  [KO:K16495]
114687121  [KO:K16496]
114687123  [KO:K16496]
114687124  [KO:K16495]
114687125  [KO:K16495]
114687126  [KO:K16495]
114687127  [KO:K16496]
114687128  Pcdhgc3; protocadherin gamma-C3 [KO:K16497]
114687129  [KO:K16495]
114687131  [KO:K16496]
114687132  Pcdhga12; protocadherin gamma-A12 [KO:K16495]
114687133  [KO:K16496]
114687135  Pcdhb15; protocadherin beta-15 [KO:K16494]
114687136  [KO:K16494]
114687138  [KO:K16494]
114687139  [KO:K16494]
114687140  [KO:K16494]
114687141  [KO:K16494]
114687142  [KO:K16494]
114687143  [KO:K16494]
114687146  [KO:K16495]
114687147  [KO:K16495]
114687148  [KO:K16496]
114687149  Pcdhga5; protocadherin gamma-A5 [KO:K16495]
114687150  [KO:K16495]
114687151  [KO:K16495]
114687153  [KO:K16496]
114687170  Tead2; transcriptional enhancer factor TEF-4 isoform X1 [KO:K09448]
114687180  Rras; ras-related protein R-Ras isoform X1 [KO:K07829]
114687296  Gabrb1; gamma-aminobutyric acid receptor subunit beta-1 [KO:K05181]
114687433  Gabra3; gamma-aminobutyric acid receptor subunit alpha-3 [KO:K05175]
114687634  Gabra2; gamma-aminobutyric acid receptor subunit alpha-2 isoform X1 [KO:K05175]
114687697  [KO:K10056]
114687896  Gabrg1; gamma-aminobutyric acid receptor subunit gamma-1 [KO:K05186]
114687963  Fzd1; frizzled-1 [KO:K02432]
114688100  [KO:K05128] [EC:2.7.10.1]
114688121  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
114688173  Gabrq; gamma-aminobutyric acid receptor subunit theta isoform X1 [KO:K05192]
114688431  Tmc4; transmembrane channel-like protein 4 [KO:K21988]
114688488  [KO:K02833]
114689127  [KO:K16669]
114689530  Gabre; gamma-aminobutyric acid receptor subunit epsilon [KO:K05185]
114689596  Lhfpl4; LHFPL tetraspan subfamily member 4 protein [KO:K23893]
114689606  Arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
114689615  Brk1; protein BRICK1 isoform X2 [KO:K05752]
114689636  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
114689819  Cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X2 [KO:K05749]
114689842  Gabrb2; gamma-aminobutyric acid receptor subunit beta-2 isoform X1 [KO:K05181]
114689843  Gabra6; gamma-aminobutyric acid receptor subunit alpha-6 isoform X1 [KO:K05175]
114689844  Gabra1; gamma-aminobutyric acid receptor subunit alpha-1 isoform X1 [KO:K05175]
114689845  Gabrg2; gamma-aminobutyric acid receptor subunit gamma-2 isoform X1 [KO:K05186]
114689852  Wwc1; protein KIBRA isoform X2 [KO:K16685]
114690292  Cib2; calcium and integrin-binding family member 2 isoform X1 [KO:K23837]
114690442  Axin2; axin-2 [KO:K04385]
114690634  Psen2; presenilin-2 isoform X1 [KO:K04522] [EC:3.4.23.-]
114690700  Ncstn; nicastrin [KO:K06171]
114690702  Vangl2; vang-like protein 2 [KO:K04510]
114690776  Adam10; disintegrin and metalloproteinase domain-containing protein 10 [KO:K06704] [EC:3.4.24.81]
114690849  Myo1e; unconventional myosin-Ie [KO:K10356]
114691045  [KO:K06172]
114691055  [KO:K06172]
114691129  Scn3b; sodium channel subunit beta-3 isoform X2 [KO:K04847]
114691196  Scn2b; sodium channel subunit beta-2 [KO:K04846]
114691197  Scn4b; sodium channel subunit beta-4 [KO:K04848]
114691309  [KO:K04393]
114691342  Afdn; afadin isoform X1 [KO:K05702]
114691439  Myo1c; unconventional myosin-Ic isoform X1 [KO:K10356]
114691442  Ywhae; 14-3-3 protein epsilon isoform X1 [KO:K06630]
114691474  Taok1; serine/threonine-protein kinase TAO1 isoform X1 [KO:K04429] [EC:2.7.11.1]
114691497  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [KO:K04368] [EC:2.7.12.2]
114691545  Myo1d; unconventional myosin-Id isoform X1 [KO:K10356]
114691777  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
114692144  Tmc7; transmembrane channel-like protein 7 [KO:K21988]
114692235  Tmc5; transmembrane channel-like protein 5 isoform X2 [KO:K21988]
114692419  Pcdh7; protocadherin-7 isoform X1 [KO:K16498]
114692455  Cdh18; cadherin-18 isoform X1 [KO:K06805]
114692457  Cdh12; cadherin-12 [KO:K06804]
114692552  Gja1; gap junction alpha-1 protein [KO:K07372]
114692606  Ywhab; 14-3-3 protein beta/alpha [KO:K16197]
114692639  Cdh22; cadherin-22 [KO:K06812]
114693019  Mapk12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
114693020  Mapk11; mitogen-activated protein kinase 11 isoform X5 [KO:K04441] [EC:2.7.11.24]
114693063  Prickle1; prickle-like protein 1 [KO:K04511]
114693209  Dvl2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
114693378  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
114693493  [KO:K02833]
114693522  Pkp3; plakophilin-3 [KO:K28841]
114693532  Ryk; LOW QUALITY PROTEIN: tyrosine-protein kinase RYK [KO:K05128] [EC:2.7.10.1]
114693534  Amotl2; LOW QUALITY PROTEIN: angiomotin-like protein 2 [KO:K06104]
114693556  Mras; ras-related protein M-Ras isoform X2 [KO:K07831]
114693595  Hras; GTPase HRas isoform X1 [KO:K02833]
114693690  Fzd10; frizzled-10 [KO:K02842]
114693850  Lats2; serine/threonine-protein kinase LATS2 isoform X1 [KO:K08791] [EC:2.7.11.1]
114693939  Vim; vimentin [KO:K07606]
114693968  Myo1g; unconventional myosin-Ig [KO:K10356]
114694003  Nf2; merlin isoform X1 [KO:K16684]
114694046  Ywhah; 14-3-3 protein eta [KO:K16198]
114694231  Rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
114694299  Ep300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
114694411  Mob1a; MOB kinase activator 1A [KO:K06685]
114694443  Ctnna2; LOW QUALITY PROTEIN: catenin alpha-2 [KO:K05691]
114694590  Lrp5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068]
114694610  Cdh17; cadherin-17 [KO:K06811]
114694636  Lhfpl2; LHFPL tetraspan subfamily member 2 protein [KO:K23893]
114694717  Wnt2; protein Wnt-2 [KO:K00182]
114694721  Met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
114695427  Ankrd6; ankyrin repeat domain-containing protein 6 isoform X1 [KO:K21435]
114695430  Gabrr1; gamma-aminobutyric acid receptor subunit rho-1 [KO:K05190]
114695452  Gabrr2; gamma-aminobutyric acid receptor subunit rho-2 [KO:K05190]
114695462  Igf1r; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
114695488  Tjp1; tight junction protein ZO-1 isoform X1 [KO:K05701]
114695609  Wnt16; protein Wnt-16 [KO:K01558]
114695763  Fzd8; frizzled-8 [KO:K02375]
114695836  Mpdz; multiple PDZ domain protein isoform X16 [KO:K06095]
114695861  Lhfpl6; LHFPL tetraspan subfamily member 6 protein [KO:K23893]
114695893  Pcdh18; protocadherin-18 isoform X1 [KO:K16499]
114696227  Tmc3; LOW QUALITY PROTEIN: transmembrane channel-like protein 3 [KO:K21988]
114696284  Ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
114696366  Fat3; protocadherin Fat 3 isoform X1 [KO:K16506]
114696474  Pcdh15; protocadherin-15 isoform X1 [KO:K16500]
114696542  [KO:K07605]
114696544  [KO:K07605]
114696553  [KO:K02833]
114696565  Krt18; keratin, type I cytoskeletal 18 [KO:K07604]
114696566  [KO:K07605]
114696567  Krt79; keratin, type II cytoskeletal 79 [KO:K07605]
114696568  Krt4; keratin, type II cytoskeletal 4 [KO:K07605]
114696569  Krt1; keratin, type II cytoskeletal 1 isoform X1 [KO:K07605]
114696570  Krt2; keratin, type II cytoskeletal 2 epidermal [KO:K07605]
114696571  [KO:K07605]
114696572  Krt72; keratin, type II cytoskeletal 72 [KO:K07605]
114696573  Krt71; keratin, type II cytoskeletal 71 [KO:K07605]
114696575  Krt5; keratin, type II cytoskeletal 5 [KO:K07605]
114696576  Krt6a; keratin, type II cytoskeletal 6A isoform X1 [KO:K07605]
114696577  [KO:K07605]
114696578  [KO:K07605]
114696580  [KO:K07605]
114696581  [KO:K07605]
114696583  [KO:K07605]
114696584  Krt80; keratin, type II cytoskeletal 80 isoform X1 [KO:K07605]
114696601  Nckap1l; nck-associated protein 1-like [KO:K05750]
114696641  Krt8; keratin, type II cytoskeletal 8 [KO:K07605]
114696642  Krt77; keratin, type II cytoskeletal 1b [KO:K07605]
114696643  [KO:K07605]
114696644  Krt74; keratin, type II cytoskeletal 74 [KO:K07605]
114696645  Krt84; keratin, type II cuticular Hb4 [KO:K07605]
114696646  Krt75; keratin, type II cytoskeletal 75 [KO:K07605]
114696647  [KO:K07605]
114696648  Krt82; keratin, type II cuticular Hb2 [KO:K07605]
114696650  [KO:K07605]
114696651  [KO:K07605]
114696653  Krt7; keratin, type II cytoskeletal 7 isoform X2 [KO:K07605]
114696679  Lima1; LIM domain and actin-binding protein 1 [KO:K23026]
114696943  Actr3; actin-related protein 3 [KO:K18584]
114697001  Pcdh19; protocadherin-19 isoform X1 [KO:K28837]
114697050  Shoc2; leucine-rich repeat protein SHOC-2 [KO:K19613]
114697060  Tcf7l2; transcription factor 7-like 2 isoform X1 [KO:K04491]
114697206  Cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
114697207  Wnt4; protein Wnt-4 [KO:K00408]
114697461  Cdh13; cadherin-13 isoform X1 [KO:K06808]
114697497  [KO:K10367]
114697594  Tead1; transcriptional enhancer factor TEF-1 isoform X1 [KO:K09448]
114697601  Rras2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
114697765  Mpp5; MAGUK p55 subfamily member 5 isoform X2 [KO:K06091]
114697781  Actn1; alpha-actinin-1 isoform X1 [KO:K05699]
114697804  [KO:K06802]
114697810  Cdh9; cadherin-9 [KO:K06801]
114697939  [KO:K05750]
114698051  Pkp1; LOW QUALITY PROTEIN: plakophilin-1 [KO:K10387]
114698172  Rock1; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.39]
114698313  Lhfpl1; LHFPL tetraspan subfamily member 1 protein [KO:K23893]
114698444  Psen1; presenilin-1 [KO:K04505] [EC:3.4.23.-]
114698576  Vangl1; vang-like protein 1 isoform X1 [KO:K04510]
114698582  Nras; GTPase NRas [KO:K07828]
114698680  Myo7a; LOW QUALITY PROTEIN: unconventional myosin-VIIa [KO:K10359]
114698691  Wnt11; protein Wnt-11 isoform X1 [KO:K01384]
114698838  Rock2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
114698856  Ywhaq; 14-3-3 protein theta [KO:K16197]
114698923  [KO:K16682]
114698927  Scn1b; sodium channel subunit beta-1 [KO:K04845]
114699199  Wnt7b; protein Wnt-7b isoform X1 [KO:K00572]
114699208  Celsr1; cadherin EGF LAG seven-pass G-type receptor 1 isoform X1 [KO:K04600]
114699348  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
114699476  Tmc2; LOW QUALITY PROTEIN: transmembrane channel-like protein 2 [KO:K21988]
114699656  Taok3; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
114699668  Pcdh8; protocadherin-8 isoform X1 [KO:K28835]
114699689  Pcdh17; protocadherin-17 isoform X1 [KO:K16499]
114699769  Pcdh20; protocadherin-20 [KO:K16498]
114699911  Fzd6; frizzled-6 [KO:K02376]
114699957  Vav3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
114699974  Celsr2; cadherin EGF LAG seven-pass G-type receptor 2 isoform X1 [KO:K04601]
114700027  Gabrr3; gamma-aminobutyric acid receptor subunit rho-3 [KO:K05190]
114700059  Actr3b; actin-related protein 3B isoform X1 [KO:K18584]
114700210  Vcl; vinculin isoform X1 [KO:K05700]
114700411  Fat2; protocadherin Fat 2 [KO:K28839]
114700533  Ush1c; harmonin isoform X1 [KO:K21877]
114700757  Wnt5b; protein Wnt-5b [KO:K00444]
114700910  [KO:K04513]
114700983  Cdh15; cadherin-15 [KO:K06809]
114701114  Ctnna3; catenin alpha-3 isoform X2 [KO:K05691]
114701162  Fat1; protocadherin Fat 1 isoform X1 [KO:K16506]
114701275  [KO:K04393]
114701284  Prickle3; prickle planar cell polarity protein 3 [KO:K04511]
114701432  Tead4; transcriptional enhancer factor TEF-3 isoform X1 [KO:K09448]
114701479  Gsk3b; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
114701847  Ctnnd2; LOW QUALITY PROTEIN: catenin delta-2 [KO:K23491]
114701908  Evl; ena/VASP-like protein isoform X1 [KO:K23487]
114701947  Wwtr1; WW domain-containing transcription regulator protein 1 isoform X1 [KO:K16820]
114702120  Wnt5a; protein Wnt-5a isoform X1 [KO:K00444]
114702169  Daam2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
114702202  Wnt9b; protein Wnt-9b [KO:K01064]
114702239  Fzd2; frizzled-2 [KO:K02235]
114702271  Wnt3; proto-oncogene Wnt-3 [KO:K00312]
114702554  Pcdh9; protocadherin-9 isoform X1 [KO:K16498]
114702641  Rere; LOW QUALITY PROTEIN: arginine-glutamic acid dipeptide repeats protein [KO:K05628]
114702820  Cdh20; cadherin-20 isoform X1 [KO:K06807]
114703063  Erbin; erbin isoform X1 [KO:K12796]
114703534  Cdh11; LOW QUALITY PROTEIN: cadherin-11 [KO:K06803]
114703536  Cdh5; LOW QUALITY PROTEIN: cadherin-5 [KO:K06533]
114703547  Cdh16; cadherin-16 isoform X1 [KO:K06810]
114703557  Cdh6; cadherin-6 isoform X1 [KO:K06798]
114703607  Nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
114703630  Stk3; serine/threonine-protein kinase 3 isoform X1 [KO:K04412]
114703643  Ywhaz; 14-3-3 protein zeta/delta [KO:K16197]
114703682  Actr2; actin-related protein 2 isoform X3 [KO:K17260]
114704218  Cdh4; cadherin-4 [KO:K06797]
114704332  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
114704341  Taok2; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
114704562  Arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
114704570  Ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
114704659  Ptk2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
114704735  Cdh23; cadherin-23 [KO:K06813]
114704787  Myo1a; unconventional myosin-Ia [KO:K10356]
114704983  [KO:K07602]
114704984  [KO:K07601]
114704985  Dsg2; desmoglein-2 [KO:K07597]
114704995  Dsg1; desmoglein-1 [KO:K07596]
114704997  Dsg3; desmoglein-3 isoform X1 [KO:K07598]
114704998  Dsc1; desmocollin-1 isoform X2 [KO:K07600]
114704999  Dsg4; desmoglein-4 [KO:K07599]
114705008  Myo1b; unconventional myosin-Ib isoform X2 [KO:K10356]
114705069  Fzd5; frizzled-5 [KO:K02375]
114705104  Ctnna1; catenin alpha-1 isoform X1 [KO:K05691]
114705120  Apc; adenomatous polyposis coli protein isoform X1 [KO:K02085]
114705144  Wnt8a; protein Wnt-8a [KO:K00714]
114705196  Celsr3; cadherin EGF LAG seven-pass G-type receptor 3 isoform X1 [KO:K04602]
114705216  Rhoa; transforming protein RhoA [KO:K04513]
114705328  Prickle4; prickle-like protein 4 isoform X1 [KO:K04511]
114705499  Actb; actin, cytoplasmic 1 [KO:K05692]
114705532  Egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
114705738  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
114706150  Tead3; transcriptional enhancer factor TEF-5 [KO:K09448]
114706152  Lhfpl5; LHFPL tetraspan subfamily member 5 protein [KO:K23893]
114706162  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
114706165  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
114706175  Ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
114706431  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
114706749  Mob1b; MOB kinase activator 1B [KO:K06685]
114706907  Ppp1r1b; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
114706915  Krt35; keratin, type I cuticular Ha5 [KO:K07604]
114706917  [KO:K07604]
114706922  [KO:K07604]
114706925  [KO:K07604]
114706930  [KO:K07604]
114706932  Krt24; keratin, type I cytoskeletal 24 [KO:K07604]
114706933  Krt25; keratin, type I cytoskeletal 25 [KO:K07604]
114706935  Krt15; keratin, type I cytoskeletal 15 [KO:K07604]
114706937  Krt20; keratin, type I cytoskeletal 20 [KO:K07604]
114706938  Krt28; keratin, type I cytoskeletal 28 [KO:K07604]
114706940  Erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
114706941  [KO:K07604]
114706942  [KO:K07604]
114706945  Krt13; keratin, type I cytoskeletal 13 [KO:K07604]
114706948  Krt34; keratin, type I cuticular Ha4 [KO:K07604]
114706949  [KO:K07604]
114706950  Krt23; keratin, type I cytoskeletal 23 [KO:K07604]
114706951  [KO:K07604]
114706953  Krt12; LOW QUALITY PROTEIN: keratin, type I cytoskeletal 12 [KO:K07604]
114706955  Krt27; keratin, type I cytoskeletal 27 [KO:K07604]
114706958  Krt40; keratin, type I cytoskeletal 40 [KO:K07604]
114706970  Krt26; keratin, type I cytoskeletal 26 [KO:K07604]
114706971  Krt39; keratin, type I cytoskeletal 39 [KO:K07604]
114706977  Krt9; keratin, type I cytoskeletal 9 [KO:K07604]
114706978  [KO:K07604]
114706979  Krt19; keratin, type I cytoskeletal 19 [KO:K07604]
114707007  Krt10; keratin, type I cytoskeletal 10 isoform X2 [KO:K07604]
114707105  Ush1g; Usher syndrome type-1G protein isoform X1 [KO:K21878]
114707263  Wnt2b; protein Wnt-2b [KO:K00182]
114707293  Fzd3; frizzled-3 isoform X1 [KO:K02329]
114707316  Ptk2b; protein-tyrosine kinase 2-beta isoform X1 [KO:K05871] [EC:2.7.10.2]
114707365  Pdgfrb; LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
114707394  Csnk1a1; casein kinase I isoform X2 [KO:K08957] [EC:2.7.11.1]
114707445  Cdh8; cadherin-8 isoform X1 [KO:K06800]
114707507  Wasf1; wiskott-Aldrich syndrome protein family member 1 isoform X1 [KO:K05753]
114707535  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
114707541  Arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
114707564  Arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
114707644  Limd1; LIM domain-containing protein 1 [KO:K16682]
114707979  Lhfpl3; LHFPL tetraspan subfamily member 3 protein [KO:K23893]
114707997  Yap1; transcriptional coactivator YAP1 isoform X1 [KO:K16687]
114708149  Wnt8b; protein Wnt-8b [KO:K00714]
114708251  Dvl1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353]
114708256  Gabrd; gamma-aminobutyric acid receptor subunit delta [KO:K05184]
114708477  Kras; GTPase KRas isoform X2 [KO:K07827]
114708546  Wnt10b; protein Wnt-10b [KO:K01357]
114708572  Wnt1; proto-oncogene Wnt-1 [KO:K03209]
114708629  Cdh2; cadherin-2 [KO:K06736]
114708721  Ajuba; LIM domain-containing protein ajuba [KO:K16682]
114708742  Cdh24; cadherin-24 [KO:K06814]
114708784  Atn1; LOW QUALITY PROTEIN: atrophin-1 [KO:K05626]
114708954  Tmc6; transmembrane channel-like protein 6 isoform X1 [KO:K21988]
114708970  Tmc8; transmembrane channel-like protein 8 isoform X5 [KO:K21988]
114708979  Cyfip1; LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1 [KO:K05749]
114709280  Arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
114709307  Wnt10a; LOW QUALITY PROTEIN: protein Wnt-10a [KO:K01357]
114709309  Des; desmin [KO:K07610]
114709311  Wnt6; protein Wnt-6 [KO:K00445]
114709466  Axin1; axin-1 isoform X1 [KO:K02157]
114709870  [KO:K06274]
114710101  Ctnnd1; catenin delta-1 isoform X5 [KO:K05690]
114710288  Pcdh10; protocadherin-10 isoform X1 [KO:K28836]
114710296  Ywhag; 14-3-3 protein gamma [KO:K16198]
114710353  Lrp6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
114710495  Gabra5; gamma-aminobutyric acid receptor subunit alpha-5 [KO:K05175]
114710496  Gabrg3; gamma-aminobutyric acid receptor subunit gamma-3 [KO:K05186]
114710497  Gabrb3; gamma-aminobutyric acid receptor subunit beta-3 isoform X1 [KO:K05181]
114710523  [KO:K04371] [EC:2.7.11.24]
114710536  Pkp2; plakophilin-2 [KO:K12642]
114710563  [KO:K10381]
114710614  [KO:K04498] [EC:2.3.1.48]
114710654  [KO:K05189]
114710708  Fzd4; frizzled-4 [KO:K02354]
114710930  Tmc1; transmembrane channel-like protein 1 [KO:K21988]
119086109  [KO:K16493]
119086255  [KO:K16493]
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  Authors
Lin WH, Cooper LM, Anastasiadis PZ
  Title
Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment.
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Front Cell Dev Biol 11:1137013 (2023)
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Biochem Soc Trans 51:2103-2115 (2023)
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Nat Rev Cardiol 16:519-537 (2019)
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Biophys Rev 13:697-706 (2021)
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Front Mol Neurosci 13:117 (2020)
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Mechanisms in cochlear hair cell mechano-electrical transduction for acquisition of sound frequency and intensity.
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Pharmacol Res 130:25-35 (2018)
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Semin Cell Dev Biol 69:91-101 (2017)
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Related
pathway
pleu04010  MAPK signaling pathway
pleu04064  NF-kappa B signaling pathway
pleu04151  PI3K-Akt signaling pathway
pleu04310  Wnt signaling pathway
pleu04390  Hippo signaling pathway
pleu04520  Adherens junction
pleu04630  JAK-STAT signaling pathway
pleu04810  Regulation of actin cytoskeleton
KO pathway
ko04519   

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