KEGG   PATHWAY: psom04120
Entry
psom04120                   Pathway                                
Name
Ubiquitin mediated proteolysis - Papaver somniferum (opium poppy)
Description
Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
psom04120  Ubiquitin mediated proteolysis
psom04120

Other DBs
GO: 0016567
Organism
Papaver somniferum (opium poppy) [GN:psom]
Gene
113344796  polyubiquitin-like [KO:K08770]
113326050  polyubiquitin-like [KO:K08770]
113349274  polyubiquitin-like [KO:K08770]
113286704  polyubiquitin-like [KO:K08770]
113348636  polyubiquitin-like [KO:K08770]
113290182  polyubiquitin 4-like [KO:K08770]
113318445  polyubiquitin 4 [KO:K08770]
113317349  polyubiquitin-like [KO:K08770]
113311590  polyubiquitin isoform X1 [KO:K08770]
113290178  polyubiquitin [KO:K08770]
113301572  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113340165  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113297672  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113323097  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113338281  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113308005  ubiquitin-60S ribosomal protein L40 [KO:K02927]
113347000  ubiquitin-40S ribosomal protein S27a [KO:K02977]
113333123  ubiquitin-40S ribosomal protein S27a [KO:K02977]
113282444  ubiquitin-40S ribosomal protein S27a [KO:K02977]
113276475  ubiquitin-40S ribosomal protein S27a-like [KO:K02977]
113284179  ubiquitin-activating enzyme E1 1-like isoform X1 [KO:K03178] [EC:6.2.1.45]
113310918  ubiquitin-activating enzyme E1 1-like isoform X1 [KO:K03178] [EC:6.2.1.45]
113339091  ubiquitin-activating enzyme E1 1-like [KO:K03178] [EC:6.2.1.45]
113355413  ubiquitin-activating enzyme E1 1-like isoform X1 [KO:K03178] [EC:6.2.1.45]
113271650  SUMO-activating enzyme subunit 1B-1-like [KO:K10684] [EC:6.2.1.45]
113281027  SUMO-activating enzyme subunit 1B-1-like [KO:K10684] [EC:6.2.1.45]
113333666  SUMO-activating enzyme subunit 2-like [KO:K10685] [EC:6.2.1.45]
113342227  SUMO-activating enzyme subunit 2-like [KO:K10685] [EC:6.2.1.45]
113336889  NEDD8-activating enzyme E1 catalytic subunit-like [KO:K10686] [EC:6.2.1.64]
113357346  NEDD8-activating enzyme E1 catalytic subunit-like [KO:K10686] [EC:6.2.1.64]
113321536  ubiquitin-conjugating enzyme E2 2 [KO:K10573] [EC:2.3.2.23]
113314241  ubiquitin-conjugating enzyme E2 2-like [KO:K10573] [EC:2.3.2.23]
113331131  ubiquitin-conjugating enzyme E2 2 [KO:K10573] [EC:2.3.2.23]
113319687  ubiquitin-conjugating enzyme E2 2 [KO:K10573] [EC:2.3.2.23]
113310299  ubiquitin-conjugating enzyme E2 2 [KO:K10573] [EC:2.3.2.23]
113276002  ubiquitin-conjugating enzyme E2 2-like [KO:K10573] [EC:2.3.2.23]
113285917  ubiquitin-conjugating enzyme E2 1-like [KO:K10573] [EC:2.3.2.23]
113286787  ubiquitin-conjugating enzyme E2 1-like [KO:K10573] [EC:2.3.2.23]
113281607  ubiquitin-conjugating enzyme E2 2-like [KO:K10573] [EC:2.3.2.23]
113313291  probable ubiquitin-conjugating enzyme E2 C [KO:K06688] [EC:2.3.2.23]
113298504  probable ubiquitin-conjugating enzyme E2 C [KO:K06688] [EC:2.3.2.23]
113318764  ubiquitin-conjugating enzyme E2 20-like [KO:K06688] [EC:2.3.2.23]
113348864  ubiquitin-conjugating enzyme E2 20-like [KO:K06688] [EC:2.3.2.23]
113288276  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
113321783  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
113321515  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
113330652  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
113339284  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
113339285  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
113285866  NEDD8-activating enzyme E1 regulatory subunit AXR1-like [KO:K06689] [EC:2.3.2.23]
113321354  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
113302314  ubiquitin-conjugating enzyme E2 5A-like [KO:K06689] [EC:2.3.2.23]
113297040  ubiquitin-conjugating enzyme E2 5A-like [KO:K06689] [EC:2.3.2.23]
113301292  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
113309698  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
113279467  ubiquitin-conjugating enzyme E2 13-like [KO:K06689] [EC:2.3.2.23]
113283021  ubiquitin-conjugating enzyme E2 2-like [KO:K06689] [EC:2.3.2.23]
113357191  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
113323203  constitutive photomorphogenesis protein 10-like isoform X1 [KO:K20217] [EC:2.3.2.23]
113310856  constitutive photomorphogenesis protein 10-like [KO:K20217] [EC:2.3.2.23]
113328087  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113328089  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113328092  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113328093  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113323241  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113343550  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113313104  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113293929  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
113314427  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
113344085  ubiquitin-conjugating enzyme E2 5 [KO:K10576] [EC:2.3.2.23]
113323246  ubiquitin-conjugating enzyme E2 4-like [KO:K10576] [EC:2.3.2.23]
113274764  ubiquitin-conjugating enzyme E2-23 kDa-like [KO:K10576] [EC:2.3.2.23]
113315260  ubiquitin-conjugating enzyme E2-23 kDa-like [KO:K10576] [EC:2.3.2.23]
113276410  ubiquitin-conjugating enzyme E2-23 kDa-like [KO:K10576] [EC:2.3.2.23]
113297932  ubiquitin-conjugating enzyme E2-23 kDa-like isoform X1 [KO:K10576] [EC:2.3.2.23]
113313529  ubiquitin-conjugating enzyme E2 5-like [KO:K10576] [EC:2.3.2.23]
113282506  ubiquitin-conjugating enzyme E2-23 kDa-like [KO:K10576] [EC:2.3.2.23]
113292767  SUMO-conjugating enzyme SCE1-like [KO:K10577]
113346684  SUMO-conjugating enzyme SCE1 [KO:K10577]
113289133  SUMO-conjugating enzyme SCE1-like [KO:K10577]
113356910  SUMO-conjugating enzyme SCE1 [KO:K10577]
113358131  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
113346920  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
113333367  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
113334403  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
113339590  ubiquitin-conjugating enzyme E2 34-like [KO:K04554] [EC:2.3.2.23]
113326761  ubiquitin-conjugating enzyme E2 34-like [KO:K04554] [EC:2.3.2.23]
113281397  ubiquitin-conjugating enzyme E2 27-like [KO:K04649] [EC:2.3.2.23]
113362814  ubiquitin-conjugating enzyme E2 27-like [KO:K04649] [EC:2.3.2.23]
113330702  NEDD8-conjugating enzyme Ubc12-like [KO:K10579] [EC:2.3.2.34]
113296349  NEDD8-conjugating enzyme Ubc12-like [KO:K10579] [EC:2.3.2.34]
113289304  NEDD8-conjugating enzyme Ubc12-like [KO:K10579] [EC:2.3.2.34]
113316403  NEDD8-conjugating enzyme Ubc12-like [KO:K10579] [EC:2.3.2.34]
113334928  NEDD8-conjugating enzyme Ubc12-like [KO:K10579] [EC:2.3.2.34]
113357087  NEDD8-conjugating enzyme Ubc12-like isoform X1 [KO:K10579] [EC:2.3.2.34]
113302242  ubiquitin-conjugating enzyme E2 36-like [KO:K10580] [EC:2.3.2.23]
113297029  ubiquitin-conjugating enzyme E2 36-like [KO:K10580] [EC:2.3.2.23]
113289962  ubiquitin-conjugating enzyme E2 36 [KO:K10580] [EC:2.3.2.23]
113280962  ubiquitin-conjugating enzyme E2 36 [KO:K10580] [EC:2.3.2.23]
113279356  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113279529  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113305069  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272984  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113275779  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113275896  probable ubiquitin-conjugating enzyme E2 25 [KO:K10581] [EC:2.3.2.24]
113281618  probable ubiquitin-conjugating enzyme E2 25 [KO:K10581] [EC:2.3.2.24]
113287631  probable ubiquitin-conjugating enzyme E2 24 [KO:K10581] [EC:2.3.2.24]
113305086  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113305097  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113291232  probable ubiquitin-conjugating enzyme E2 23 isoform X1 [KO:K10581] [EC:2.3.2.24]
113313089  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113274124  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113275111  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113283251  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113288986  probable ubiquitin-conjugating enzyme E2 23 [KO:K10581] [EC:2.3.2.24]
113316117  probable ubiquitin-conjugating enzyme E2 23 [KO:K10581] [EC:2.3.2.24]
113323712  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113306868  probable ubiquitin-conjugating enzyme E2 24 [KO:K10581] [EC:2.3.2.24]
113272906  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272911  probable ubiquitin-conjugating enzyme E2 25 [KO:K10581] [EC:2.3.2.24]
113272913  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272922  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272923  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272924  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113272925  probable ubiquitin-conjugating enzyme E2 25 [KO:K10581] [EC:2.3.2.24]
113272926  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113279073  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113356289  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113358707  putative ubiquitin-conjugating enzyme E2 38 [KO:K10581] [EC:2.3.2.24]
113348823  probable ubiquitin-conjugating enzyme E2 23 [KO:K10581] [EC:2.3.2.24]
113309296  ubiquitin-conjugating enzyme E2 22-like [KO:K10583] [EC:2.3.2.23]
113322012  ubiquitin-conjugating enzyme E2 22-like [KO:K10583] [EC:2.3.2.23]
113288711  ubiquitin-conjugating enzyme 15-like [KO:K10688] [EC:2.3.2.23 2.3.2.25]
113288754  ubiquitin-conjugating enzyme 15 [KO:K10688] [EC:2.3.2.23 2.3.2.25]
113349812  ubiquitin-conjugating enzyme 15-like isoform X1 [KO:K10688] [EC:2.3.2.23 2.3.2.25]
113357704  ubiquitin-conjugating enzyme 15-like [KO:K10688] [EC:2.3.2.23 2.3.2.25]
113313190  E3 ubiquitin-protein ligase UPL7-like isoform X1 [KO:K10588] [EC:2.3.2.26]
113338817  E3 ubiquitin-protein ligase UPL7-like [KO:K10588] [EC:2.3.2.26]
113346965  E3 ubiquitin-protein ligase UPL6-like [KO:K10589] [EC:2.3.2.26]
113311875  E3 ubiquitin-protein ligase UPL4-like [KO:K10590] [EC:2.3.2.26]
113290949  E3 ubiquitin-protein ligase UPL3-like [KO:K10590] [EC:2.3.2.26]
113288946  E3 ubiquitin-protein ligase UPL3-like [KO:K10590] [EC:2.3.2.26]
113313424  E3 ubiquitin-protein ligase UPL4-like isoform X1 [KO:K10590] [EC:2.3.2.26]
113320512  E3 ubiquitin-protein ligase UPL4-like isoform X1 [KO:K10590] [EC:2.3.2.26]
113288185  E3 ubiquitin-protein ligase UPL1-like isoform X1 [KO:K10592] [EC:2.3.2.26]
113301975  E3 ubiquitin-protein ligase UPL1-like isoform X1 [KO:K10592] [EC:2.3.2.26]
113357570  E3 ubiquitin-protein ligase UPL2-like isoform X1 [KO:K10592] [EC:2.3.2.26]
113349689  E3 ubiquitin-protein ligase UPL2-like isoform X1 [KO:K10592] [EC:2.3.2.26]
113332809  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113333939  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113281167  probable ubiquitin conjugation factor E4 isoform X1 [KO:K10597] [EC:2.3.2.27]
113300180  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113327524  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113324629  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113335218  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113335225  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113360787  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
113284394  E3 ubiquitin-protein ligase CHIP-like isoform X1 [KO:K09561] [EC:2.3.2.27]
113355550  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
113288551  peptidyl-prolyl cis-trans isomerase CYP65-like [KO:K10598] [EC:5.2.1.8]
113286960  peptidyl-prolyl cis-trans isomerase CYP65-like [KO:K10598] [EC:5.2.1.8]
113318584  pre-mRNA-processing factor 19-like [KO:K10599] [EC:2.3.2.27]
113333695  pre-mRNA-processing factor 19-like [KO:K10599] [EC:2.3.2.27]
113299001  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113321266  E3 ubiquitin-protein ligase DIS1-like [KO:K04506] [EC:2.3.2.27]
113322118  E3 ubiquitin-protein ligase SINAT2-like [KO:K04506] [EC:2.3.2.27]
113322667  E3 ubiquitin-protein ligase SINAT4-like [KO:K04506] [EC:2.3.2.27]
113339950  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113339951  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113275455  E3 ubiquitin-protein ligase SINA-like 10 [KO:K04506] [EC:2.3.2.27]
113310479  E3 ubiquitin-protein ligase DIS1-like [KO:K04506] [EC:2.3.2.27]
113310345  E3 ubiquitin-protein ligase SINAT2-like [KO:K04506] [EC:2.3.2.27]
113310890  E3 ubiquitin-protein ligase SINAT4-like [KO:K04506] [EC:2.3.2.27]
113323087  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113323088  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113282153  E3 ubiquitin-protein ligase SINA-like 10 [KO:K04506] [EC:2.3.2.27]
113358438  E3 ubiquitin-protein ligase SINAT5-like [KO:K04506] [EC:2.3.2.27]
113304459  WD repeat-containing protein RUP2-like [KO:K10143] [EC:2.3.2.27]
113288046  E3 ubiquitin-protein ligase COP1-like [KO:K10143] [EC:2.3.2.27]
113303769  E3 ubiquitin-protein ligase COP1-like [KO:K10143] [EC:2.3.2.27]
113274915  WD repeat-containing protein RUP2-like [KO:K10143] [EC:2.3.2.27]
113319544  E3 ubiquitin-protein ligase MIEL1-like [KO:K10144] [EC:2.3.2.27]
113299786  probable E3 ubiquitin-protein ligase RZFP34 [KO:K10144] [EC:2.3.2.27]
113307802  E3 ubiquitin-protein ligase RZFP34-like [KO:K10144] [EC:2.3.2.27]
113298694  E3 ubiquitin-protein ligase RZFP34-like [KO:K10144] [EC:2.3.2.27]
113303685  probable E3 ubiquitin-protein ligase RZFP34 [KO:K10144] [EC:2.3.2.27]
113307977  E3 ubiquitin-protein ligase RZFP34-like isoform X1 [KO:K10144] [EC:2.3.2.27]
113350203  E3 ubiquitin-protein ligase MIEL1-like [KO:K10144] [EC:2.3.2.27]
113349615  E3 ubiquitin-protein ligase MIEL1-like [KO:K10144] [EC:2.3.2.27]
113357485  E3 ubiquitin-protein ligase MIEL1-like [KO:K10144] [EC:2.3.2.27]
113325346  uncharacterized protein LOC113325346 [KO:K04706] [EC:2.3.2.-]
113299219  E4 SUMO-protein ligase PIAL2-like isoform X1 [KO:K04706] [EC:2.3.2.-]
113321831  nascent polypeptide-associated complex subunit alpha, muscle-specific form-like isoform X1 [KO:K04706] [EC:2.3.2.-]
113344229  nascent polypeptide-associated complex subunit alpha, muscle-specific form-like isoform X1 [KO:K04706] [EC:2.3.2.-]
113344266  E4 SUMO-protein ligase PIAL2-like isoform X1 [KO:K04706] [EC:2.3.2.-]
113358389  E4 SUMO-protein ligase PIAL2-like isoform X1 [KO:K04706] [EC:2.3.2.-]
113297597  ERAD-associated E3 ubiquitin-protein ligase HRD1B-like isoform X1 [KO:K10601] [EC:2.3.2.27]
113301786  ERAD-associated E3 ubiquitin-protein ligase HRD1B-like [KO:K10601] [EC:2.3.2.27]
113288477  E3 ubiquitin-protein ligase FANCL-like isoform X1 [KO:K10606] [EC:2.3.2.27]
113286812  E3 ubiquitin-protein ligase FANCL-like [KO:K10606] [EC:2.3.2.27]
113327705  RING-box protein 1a-like [KO:K03868] [EC:2.3.2.32]
113339765  RING-box protein 1-like [KO:K03868] [EC:2.3.2.32]
113293923  RING-box protein 1a [KO:K03868] [EC:2.3.2.32]
113326900  RING-box protein 1-like [KO:K03868] [EC:2.3.2.32]
113317632  cullin-1-like [KO:K03347]
113350222  cullin-1-like [KO:K03347]
113309902  SKP1-like protein 1A [KO:K03094]
113325816  SKP1-like protein 11 [KO:K03094]
113325852  SKP1-like protein 11 [KO:K03094]
113325854  SKP1-like protein 11 [KO:K03094]
113325856  SKP1-like protein 1B [KO:K03094]
113325858  SKP1-like protein 4 [KO:K03094]
113336224  SKP1-like protein 1B [KO:K03094]
113324972  SKP1-like protein 1A [KO:K03094]
113343901  SKP1-like protein 1A [KO:K03094]
113343902  SKP1-like protein 1A [KO:K03094]
113343903  SKP1-like protein 4 [KO:K03094]
113343920  SKP1-like protein 1 [KO:K03094]
113343923  SKP1-like protein 1 [KO:K03094]
113280707  SKP1-like protein 1B [KO:K03094]
113291139  SKP1-like protein 1B [KO:K03094]
113339011  SKP1-like protein 1A [KO:K03094]
113329250  SKP1-like protein 1B [KO:K03094]
113329251  SKP1-like protein 1B [KO:K03094]
113331212  SKP1-like protein 1 [KO:K03094]
113290467  SKP1-like protein 1B [KO:K03094]
113290468  SKP1-like protein 14 [KO:K03094]
113290471  SKP1-like protein 11 [KO:K03094]
113305808  SKP1-like protein 1A [KO:K03094]
113336047  SKP1-like protein 1B [KO:K03094]
113325097  SKP1-like protein 1A [KO:K03094]
113338136  SKP1-like protein 1A isoform X1 [KO:K03094]
113338609  SKP1-like protein 1A [KO:K03094]
113338618  SKP1-like protein 1B [KO:K03094]
113338625  SKP1-like protein 1B [KO:K03094]
113284142  SKP1-like protein 1 [KO:K03094]
113342122  SKP1-like protein 1A [KO:K03094]
113278401  SKP1-like protein 1A [KO:K03094]
113278406  SKP1-like protein 1B [KO:K03094]
113288975  SKP1-like protein 1B [KO:K03094]
113318865  SKP1-like protein 1 [KO:K03094]
113273337  SKP1-like protein 11 [KO:K03094]
113329765  SKP1-like protein 11 [KO:K03094]
113272569  SKP1-like protein 1B [KO:K03094]
113272578  SKP1-like protein 1A [KO:K03094]
113272586  SKP1-like protein 1A [KO:K03094]
113272594  SKP1-like protein 1B [KO:K03094]
113272602  SKP1-like protein 3 [KO:K03094]
113329988  SKP1-like protein 1B [KO:K03094]
113335698  SKP1-like protein 1B [KO:K03094]
113346771  SKP1-like protein 1B [KO:K03094]
113278557  SKP1-like protein 1 [KO:K03094]
113278558  SKP1-like protein 1 [KO:K03094]
113352218  SKP1-like protein 1 [KO:K03094]
113352219  SKP1-like protein 1A [KO:K03094]
113352221  SKP1-like protein 1A [KO:K03094]
113352222  SKP1-like protein 1 [KO:K03094]
113352223  SKP1-like protein 1 [KO:K03094]
113352224  SKP1-like protein 1 [KO:K03094]
113352225  SKP1-like protein 1A [KO:K03094]
113352227  SKP1-like protein 1A [KO:K03094]
113354168  SKP1-like protein 4 [KO:K03094]
113350461  SKP1-like protein 4 [KO:K03094]
113352807  SKP1-like protein 1B [KO:K03094]
113354522  SKP1-like protein 4 [KO:K03094]
113353331  SKP1-like protein 1B [KO:K03094]
113353340  SKP1-like protein 1A isoform X1 [KO:K03094]
113352228  SKP1-like protein 1A [KO:K03094]
113352229  SKP1-like protein 1A [KO:K03094]
113352230  SKP1-like protein 1A [KO:K03094]
113352231  SKP1-like protein 1A [KO:K03094]
113352232  SKP1-like protein 1 [KO:K03094]
113352234  SKP1-like protein 9 [KO:K03094]
113352235  SKP1-like protein 1 [KO:K03094]
113359629  SKP1-like protein 4 [KO:K03094]
113351107  SKP1-like protein 1B [KO:K03094]
113352308  SKP1-like protein 1B [KO:K03094]
113350359  SKP1-like protein 1A [KO:K03094]
113352788  SKP1-like protein 1A [KO:K03094]
113346432  F-box protein SKP2A-like isoform X1 [KO:K03875]
113356462  F-box protein SKP2A-like isoform X1 [KO:K03875]
113275479  elongin-C-like [KO:K03872]
113282137  elongin-C-like [KO:K03872]
113344057  uncharacterized protein LOC113344057 isoform X1 [KO:K03873]
113275970  cullin-3A-like [KO:K03869]
113281664  cullin-3A-like [KO:K03869]
113298005  cullin-3A-like [KO:K03869]
113295464  cullin-4-like [KO:K10609]
113287341  cullin-4-like [KO:K10609]
113279444  DNA damage-binding protein 1 [KO:K10610]
113290118  DNA damage-binding protein 1-like [KO:K10610]
113322970  protein DAMAGED DNA-BINDING 2-like [KO:K10140]
113310876  protein DAMAGED DNA-BINDING 2-like isoform X1 [KO:K10140]
113283495  WD repeat-containing protein ATCSA-1-like [KO:K10570]
113356682  WD repeat-containing protein ATCSA-1-like [KO:K10570]
113297476  light-mediated development protein DET1-like isoform X1 [KO:K10571]
113301888  light-mediated development protein DET1-like [KO:K10571]
113332784  anaphase-promoting complex subunit 11-like [KO:K03358]
113332366  anaphase-promoting complex subunit 11 [KO:K03358]
113319250  anaphase-promoting complex subunit 2-like isoform X1 [KO:K03349]
113300418  anaphase-promoting complex subunit 2-like isoform X1 [KO:K03349]
113304778  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113271500  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113271505  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113299368  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113304526  cell division cycle 20.1, cofactor of APC complex-like isoform X1 [KO:K03363]
113281219  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113273688  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113349121  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113349122  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113349123  cell division cycle 20.2, cofactor of APC complex-like [KO:K03363]
113313393  protein FIZZY-RELATED 3-like [KO:K03364]
113275019  protein FIZZY-RELATED 2-like [KO:K03364]
113293093  protein FIZZY-RELATED 3-like [KO:K03364]
113304605  protein FIZZY-RELATED 2-like [KO:K03364]
113310484  protein FIZZY-RELATED 3-like [KO:K03364]
113344710  protein FIZZY-RELATED 3-like [KO:K03364]
113310274  anaphase-promoting complex subunit 1-like [KO:K03348]
113322049  anaphase-promoting complex subunit 1-like isoform X1 [KO:K03348]
113348183  cell division cycle protein 27 homolog B-like [KO:K03350]
113349183  cell division cycle protein 27 homolog B-like [KO:K03350]
113297721  anaphase-promoting complex subunit 4-like isoform X1 [KO:K03351]
113301469  anaphase-promoting complex subunit 4-like isoform X1 [KO:K03351]
113301850  anaphase-promoting complex subunit 5-like isoform X1 [KO:K03352]
113356216  anaphase-promoting complex subunit 5-like isoform X1 [KO:K03352]
113304309  anaphase-promoting complex subunit 6-like [KO:K03353]
113297006  anaphase-promoting complex subunit 6-like isoform X1 [KO:K03353]
113318988  anaphase-promoting complex subunit 7-like [KO:K03354]
113350215  anaphase-promoting complex subunit 7-like [KO:K03354]
113319597  anaphase-promoting complex subunit 8-like [KO:K03355]
113334162  anaphase-promoting complex subunit 8-like [KO:K03355]
113329298  anaphase-promoting complex subunit 10-like [KO:K03357]
113285985  anaphase-promoting complex subunit 10-like [KO:K03357]
113323024  anaphase-promoting complex subunit 13-like [KO:K12456]
113307675  anaphase-promoting complex subunit 13 [KO:K12456]
Reference
PMID:16922370
  Authors
Kamura T.
  Title
[Cullin-based E3 family]
  Journal
Tanpakushitsu Kakusan Koso 51:1167-72 (2006)
Reference
PMID:16922408
  Authors
Matsuda N.
  Title
[Overview: hereditary disorders caused by dysfunction of ubiquitylation]
  Journal
Tanpakushitsu Kakusan Koso 51:1402-7 (2006)
Reference
PMID:16922367
  Authors
Tokunaga F.
  Title
[E2 ubiquitin-conjugating enzymes: structures and functions]
  Journal
Tanpakushitsu Kakusan Koso 51:1150-6 (2006)
Reference
PMID:16816840
  Authors
Nalepa G, Rolfe M, Harper JW.
  Title
Drug discovery in the ubiquitin-proteasome system.
  Journal
Nat Rev Drug Discov 5:596-613 (2006)
DOI:10.1038/nrd2056
Reference
PMID:16405856
  Authors
Hsu YJ, Goodman SR.
  Title
Spectrin and ubiquitination: a review.
  Journal
Cell Mol Biol (Noisy-le-grand) Suppl 51:OL801-7 (2005)
Reference
PMID:12944364
  Authors
Hatakeyama S, Nakayama KI.
  Title
Ubiquitylation as a quality control system for intracellular proteins.
  Journal
J Biochem 134:1-8 (2003)
DOI:10.1093/jb/mvg106
Reference
PMID:17588513
  Authors
Lee J, Zhou P.
  Title
DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase.
  Journal
Mol Cell 26:775-80 (2007)
DOI:10.1016/j.molcel.2007.06.001
Related
pathway
psom03050  Proteasome
KO pathway
ko04120   
LinkDB

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