Prodrug | Active form | Reaction class | Reactant pair (Pathway map) |
Chemical structure transformation pattern | ||
KEGG ID | Name | KEGG ID | Name | |||
C07049 D08070 DG00928 |
Imipramine | C06943 D07791 |
Desipramine | RC00181 | C07049_C06943 | |
C07108 D08559 DG00734 |
Tamoxifen | C16547 | Endoxifen | RC00181 RC00490 |
C07108_C16546 C16546_C16547 (map00982) |
|
C06174 DG01076 |
Codeine | C01516 D08233 |
Morphine | RC00392 | C06174_C01516 (map00982) |
|
D00426 | Risperidone | C21516 D05339 |
Paliperidone | RC00277 | D00426_C21516 | |
D01518 | Alfacalcidol | C01673 D00129 |
Calcitriol | RC00963 | D01518_C01673 | |
C07371 D00474 |
Primidone | C07434 D00506 |
Phenobarbital | C07371_C07434 | ||
D01244 | Tegafur | C07649 D00584 |
Fluorouracil | RC00063 | C12673_C07649 (map00983) |
|
C07888 D07760 DG00675 |
Cyclophosphamide | C07643 | 4-Hydroxycyclophosphamide | RC02241 | C07888_C07643 (map00982) |
|
C07047 D00343 |
Ifosfamide | C16553 | 4-Hydroxyifosfamide | RC01203 | C07047_C16553 (map00982) |
|
D10704 | Evofosfamide | C21578 | Bromo-isophosphoramide mustard | RC02242 | D10704_C21578 | |
D05868 | Sodium phenylbutyrate | C07086 | Phenylacetate | D05868_C07086 | ||
C00355 D00059 |
Levodopa | C03758 D07870 |
Dopamine | RC00299 | C00355_C03758 (map00350) |
|
C12739 D01309 |
Doxifluridine | C07649 D00584 |
Fluorouracil | RC00063 | C12739_C07649 (map00983) |
|
D03690 | Desciclovir | C06810 D00222 |
Aciclovir | D03690_C06810 | ||
D00317 | Famciclovir | C07417 D05407 |
Penciclovir | D00317_C07417 | ||
D01981 | Ximelagatran | C21551 D07143 |
Melagatran | D01981_C21551 | ||
D00359 | Lovastatin | C21130 | Lovastatin acid | D00359_C21130 | ||
D00434 | Simvastatin | C21581 | Simvastatin acid | D00434_C21581 | ||
D01633 | Enocitabine | C02961 D00168 |
Cytarabine | RC00416 | D01633_C02961 | |
D03046 | Cytarabine ocfosphate | C02961 D00168 |
Cytarabine | C21596_C02961 | ||
D07377 DG01060 |
Bambuterol | C07129 D08570 |
Terbutaline | D07377_C07129 | ||
C06963 D01017 DG01129 |
Dipivefrin | C00788 D00095 |
Adrenaline (Epinephrine) | RC02393 | C06963_C00788 | |
D07294 DG00828 |
Propacetamol | C06804 D00217 |
Acetaminophen | RC00476 | D07294_C06804 | |
D08664 DG00647 |
Valaciclovir | C06810 D00222 |
Aciclovir | RC00041 | D08664_C06810 | |
D02495 DG00649 |
Valganciclovir | C07019 D00333 |
Ganciclovir | RC00041 | D02495_C07019 | |
D10894 DG02199 |
Valtorcitabine | C21554 D06196 |
Torcitabine | RC00055 | D10894_C21554 | |
C12796 D01361 |
Erythromycin ethylsuccinate | C01912 D00140 |
Erythromycin | RC00055 | C12796_C01912 | |
D02525 | Erythromycin propionate | C01912 D00140 |
Erythromycin | RC00055 | D02525_C01912 | |
C21595 (D02523) |
Erythromycin acistrate | C01912 D00140 |
Erythromycin | RC00055 | C21595_C01912 | |
D05351 DG00604 |
Josamycin propionate | C12662 D01235 |
Josamycin | RC00055 | D05351_C12662 | |
D05340 DG00907 |
Paliperidone palmitate | C21516 D05339 |
Paliperidone | RC00055 | D05340_C21516 | |
C07955 D00792 |
Fluphenazine enanthate | C07010 D07977 |
Fluphenazine | RC00041 | C07955_C07010 | |
C07956 D00793 |
Fluphenazine decanoate | C07010 D07977 |
Fluphenazine | RC00041 | C07956_C07010 | |
D01898 DG00885 |
Haloperidol decanoate | C01814 D00136 |
Haloperidol | D01898_C01814 | ||
C11727 D07675 DG00399 |
Chloramphenicol succinate | C00918 D00104 |
Chloramphenicol | RC00041 | C11727_C00918 | |
C11726 D01072 |
Chloramphenicol palmitate | C00918 D00104 |
Chloramphenicol | RC00041 | C11726_C00918 | |
D07674 | Chloramphenicol stearate | C00918 D00104 |
Chloramphenicol | RC00041 | D07674_C00918 | |
C21598 (D09547) |
Laninamivir octanoate | C21557 D09410 |
Laninamivir | RC00041 | C21598_C21557 | |
C21594 (D01990) |
Clindamycin palmitate | C06914 D00277 |
Clindamycin | RC00055 | C21594_C06914 | |
C06534 D07286 DG01003 |
Diamorphine (Heroin) | C01516 D08233 |
Morphine | RC01611 | C06534_C01516 | |
D07285 DG00812 |
Nicomorphine | C01516 D08233 |
Morphine | RC01611 | D07285_C01516 | |
D10612 DG01850 |
Benzhydrocodone | C08024 D08045 |
Hydrocodone | D10612_C08024 | ||
D01794 DG00310 |
Bopindolol | C21520 | 18-502 | D07537_C21520 | ||
C16641 D08086 DG00726 |
Irinotecan | C11173 | SN-38 | RC00476 | C16641_C11173 (map00983) |
|
C07908 D00752 DG00739 |
Mycophenolate mofetil | C20380 D05096 |
Mycophenolic acid | RC00020 | C07908_C20380 | |
D01122 | Ibuprofen piconol | C01588 D00126 |
Ibuprofen | RC00020 | D01122_C01588 | |
D02199 DG00443 |
Carfecillin | C06869 D07614 |
Carbenicillin | RC00475 | C11752_C06869 | |
D08329 | Penethamate hydriodide | C05551 D02336 |
Benzylpenicillin | RC00020 | D08329_C05551 | |
D01565 | Indometacin farnesil | C01926 D00141 |
Indometacin | RC00020 | D01565_C01926 | |
D01582 | Acemetacin | C01926 D00141 |
Indometacin | RC00020 | D01582_C01926 | |
D07304 | Melevodopa | C00355 D00059 |
Levodopa | RC00460 | D07304_C00355 | |
D01132 | Tazarotene | C21518 | Tazarotenic acid | RC00020 | D01132_C21518 | |
D00383 | Trandolapril | C21515 | Trandolaprilat | RC00020 | D00383_C21515 | |
C07707 D00624 DG00337 |
Perindopril | C21517 | Perindoprilat | RC00020 | C07706_C21517 | |
C07398 D03752 DG00338 |
Quinapril | C21540 D03773 |
Quinaprilat | RC00020 | C07398_C21540 | |
C06843 D07499 DG00339 |
Benazepril | C21541 D03077 |
Benazeprilat | RC00020 | C06843_C21541 | |
D07699 DG00340 |
Cilazapril | C17309 | Cilazaprilat | RC00020 | D07699_C17309 | |
D08566 DG00345 |
Temocapril | C11373 | Temocaprilat | RC00020 | D08566_C11373 | |
C06977 D07892 DG00335 |
Enalapril | C11720 | Enalaprilat | RC00020 | C06977_C11720 | |
D08068 DG00347 |
Imidapril | C21519 | Imidaprilat | RC00020 | D08068_C21519 | |
D07781 DG00343 |
Delapril | C21575 | Delaprilat | RC00020 | D07781_C21575 | |
D01900 | Alacepril | C06867 D00251 |
Captopril | D01900_C06867 | ||
D08688 DG00346 |
Zofenopril | C21576 | Zofenoprilat | RC00004 | D08688_C21576 | |
C07016 D07992 DG00341 |
Fosinopril | C21542 D03772 |
Fosinoprilat | C07016_C21542 | ||
D01853 | Miproxifene phosphate | C21549 | Miproxifene | D01853_C21549 | ||
D01907 | Fludarabine phosphate | C21550 D07966 |
Fludarabine | D01907_C21550 | ||
D02497 DG00656 |
Fosamprenavir | C08086 D00894 |
Amprenavir | D02497_C08086 | ||
C13031 D02398 DG00724 |
Estramustine phosphate sodium | C11228 D04066 |
Estramustine | C13031_C11228 | ||
C08145 D00946 DG00466 |
Diethylstilbestrol diphosphate | C07620 D00577 |
Diethylstilbestrol | RC01436 | C08145_C07620 | |
C11728 D01073 DG00435 |
Clindamycin phosphate | C06914 D00277 |
Clindamycin | C11728_C06914 | ||
D01429 DG00371 |
Fosfluconazole | C07002 D00322 |
Fluconazole | RC01439 | D01429_C07002 | |
C07840 D07993 DG00847 |
Fosphenytoin | C07443 D00512 |
Phenytoin | C07840_C07443 | ||
D04257 | Fospropofol disodium | C07523 D00549 |
Propofol | RC01372 | D04257_C07523 | |
D10707 DG01860 |
Fostemsavir | C21558 D10734 |
Temsavir | RC00856 | D10707_C21558 | |
D06597 | Fosaprepitant | C21555 D02968 |
Aprepitant | D10895_C21555 | ||
D01784 | Carmofur | C07649 D00584 |
Fluorouracil | RC01908 | D01784_C07649 (map00983) |
|
C07659 D02440 |
Phthalylsulfathiazole | C11169 D01047 |
Sulfathiazole | RC00416 | C07659_C11169 | |
C11745 D07060 DG00088 |
Succinylsulfathiazole | C11169 D01047 |
Sulfathiazole | RC00416 | C11745_C11169 | |
D07562 DG01214 |
Alatrofloxacin | C07664 D08654 |
Trovafloxacin | RC00166 | D07562_C07664 | |
D03716 DG00759 |
Parecoxib | C21552 D02709 |
Valdecoxib | D03716_C21552 | ||
D08130 DG00973 |
Lisdexamfetamine | C07884 D03740 |
Dextroamphetamine (Dexamfetamine) | D08130_C07884 | ||
D10896 DG02201 |
Pomaglumetad methionil | C21577 | LY404039 | D10896_C21577 | ||
D08220 DG00224 |
Midodrine | C21521 | Deglymidodrine | RC00096 | D08220_C21521 | |
C01956 D00144 |
Pyrazinamide | C19915 | Pyrazinoic acid (POA) | RC00100 | C01956_C19915 | |
D11472 | Remdesivir | C22275 | GS-441524 | D11472_C22275 | ||
D10428 | Tenofovir alafenamide | C17407 | Tenofovir | D10428_C17407 | ||
C13480 (D01982) |
Tenofovir disoproxil | C17407 | Tenofovir | C13480_C17407 | ||
D01655 | Adefovir dipivoxil | C11277 D02768 |
Adefovir | D01655_C11277 | ||
D10355 | Aripiprazole cavoxil | C12564 D01164 |
Aripiprazole | D10355_C12564 | ||
D10364 | Aripiprazole lauroxil | C12564 D01164 |
Aripiprazole | D10364_C12564 | ||
D01397 | Ampiroxicam | C01608 D00127 |
Piroxicam | RC03192 | D01397_C01608 | |
D08861 | Arbaclofen placarbil | C21605 D09791 |
Arbaclofen (R-Baclofen) | RC00744 | D08861_C21605 | |
D09539 | Gabapentin enacarbil | C07018 D00332 |
Gabapentin | RC00744 | D09539_C07018 | |
C07709 D00626 |
Candesartan cilexetil | C07468 D00522 |
Candesartan | RC00094 | C07709_C07468 | |
D01475 | Flurbiprofen axetil | C07013 D00330 |
Flurbiprofen | RC00094 | D01475_C07013 | |
C08107 D00914 |
Cefuroxime axetil | C06894 D00262 |
Cefuroxime | RC00094 | C08107_C06894 | |
D03431 | Cefuroxime pivoxetil | C06894 D00262 |
Cefuroxime | RC00094 | D03431_C06894 | |
C08115 D00920 |
Cefpodoxime proxetil | C08114 D07650 |
Cefpodoxime | RC00094 | C08115_C08114 | |
C12861 (D01415) |
Cefotiam hexetil | C21544 D07648 |
Cefotiam | RC00094 | C12861_C21544 | |
D01628 | Cefditoren pivoxil | C21546 D07639 |
Cefditoren | D01628_C21546 | ||
D01686 | Cefteram pivoxil | C21548 D07655 |
Cefteram | RC00020 | D01686_C21548 | |
C13141 (D01680) |
Cefcapene pivoxil | C21547 D07638 |
Cefcapene | RC00020 | C13141_C21547 | |
C21592 (D09793) |
Ceftizoxime alapivoxil | C06890 D07658 |
Ceftizoxime | C21592_C06890 | ||
D02889 DG00523 |
Pivmecillinam | C21545 D02888 |
Mecillinam | RC00020 | D02889_C21545 | |
D09598 | Tebipenem pivoxil | C21522 | Tebipenem | RC00020 | D09598_C21522 | |
C08122 D07487 DG00522 |
Bacampicillin | C06574 D00204 |
Ampicillin | RC00094 | C08122_C06574 | |
C11750 D08396 DG00518 |
Pivampicillin | C06574 D00204 |
Ampicillin | RC00020 | C11750_C06574 | |
D05805 | Sarmoxicillin | C06827 D07452 |
Amoxicillin | D05805_C06827 | ||
C11729 D01074 DG00532 |
Hetacillin | C06574 D00204 |
Ampicillin | C11729_C06574 | ||
D01144 | Prulifloxacin | C14492 | Ulifloxacin | D01144_C14492 | ||
D01204 | Olmesartan medoxomil | C21543 D05246 |
Olmesartan | RC00020 | D01204_C21543 | |
D01602 | Mepitiostane | C12694 D01265 |
Epitiostanol | RC00077 | D01602_C12694 | |
D01903 | Docarpamine | C03758 D07870 |
Dopamine | D01903_C03758 | ||
D07144 | Dabigatran etexilate | C21556 D09707 |
Dabigatran | D07144_C21556 | ||
D07061 | Acediasulfone sodium | C07666 D00592 |
Dapsone | RC00121 | D07061_C07666 | |
D07446 | Amfetaminil | C07514 D07445 |
Amphetamine | RC00283 | D07446_C07514 | |
D10715 | Mipsagargin | C21580 | 12ADT-Asp | RC00141 | D10715_C21580 | |
C07576 | Psilocybin | C08312 | Psilocin | RC00151 | C07576_C08312 (map00901) |