KEGG   REACTION: R00484
Entry
R00484                      Reaction                               
Name
N-carbamoyl-L-aspartate amidohydrolase
Definition
N-Carbamoyl-L-aspartate + H2O <=> L-Aspartate + CO2 + Ammonia
Equation
C00438 + C00001 <=> C00049 + C00011 + C00014
Reaction class
RC00064  C00049_C00438
Enzyme
3.5.1.7
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.7
     R00484  N-Carbamoyl-L-aspartate + H2O <=> L-Aspartate + CO2 + Ammonia
Other DBs
RHEA: 14368
LinkDB

KEGG   RCLASS: RC00064
Entry
RC00064                     RClass                                 
Definition
N1a-N1b:*-C5a:C1c-C1c
Reactant pair
C00012_C03193    C00017_C02429    C00017_C16739
C00025_C00415    C00025_C00624    C00025_C00876
C00025_C03541    C00025_C04305    C00025_C05595
C00025_C05829    C00025_C05928    C00025_C05929
C00025_C05931    C00025_C09332    C00025_C12270
C00025_C18802    C00025_C19151    C00025_C19152
C00025_C20775    C00025_C20776    C00025_C20948
C00025_C22053    C00041_C01212    C00041_C02999
C00041_C17950    C00045_C03363    C00047_C05341
C00047_C05892    C00047_C19889    C00047_C21160
C00049_C00438    C00049_C01042    C00049_C02715
C00049_C04823    C00049_C19710    C00049_C22224
C00051_C01419    C00062_C02993    C00062_C03296
C00062_C05340    C00062_C19713    C00062_C20910
C00064_C02716    C00064_C04148    C00077_C00437
C00077_C20951    C00077_C21680    C00079_C02135
C00079_C03519    C00082_C01392    C00097_C00669
C00097_C04352    C00097_C21437    C00123_C02710
C00123_C20964    C00133_C00993    C00133_C03738
C00133_C04702    C00133_C04882    C00135_C00386
C00135_C00884    C00135_C02997    C00151_C02850
C00151_C03740    C00151_C11529    C00151_C16116
C00151_C21099    C00151_C21509    C00183_C20962
C00183_C20965    C00188_C16594    C00188_C20917
C00195_C00319    C00217_C00692    C00217_C06379
C00217_C22611    C00327_C15532    C00402_C06380
C00405_C03135    C00405_C05226    C00405_C06378
C00407_C20963    C00499_C02091    C00525_C03137
C00525_C03414    C00550_C03640    C00666_C04390
C00666_C04421    C00680_C04877    C00740_C19719
C00836_C12126    C00956_C19886    C00993_C04702
C00993_C04882    C01021_C20735    C01152_C01262
C01165_C01250    C01419_C21858    C01610_C07032
C02166_C05951    C02265_C05620    C02320_C05729
C02356_C21015    C02385_C05340    C02471_C02755
C02512_C05711    C02671_C03933    C02671_C16690
C03283_C19929    C03803_C04341    C03955_C05554
C03955_C20333    C03999_C04457    C04650_C17952
C04877_C20925    C05156_C05157    C05689_C05695
C05726_C05727    C05952_C06462    C06457_C17951
C06717_C19703    C07027_C07028    C07394_C16524
C12144_C12145    C16739_C21386    C17549_C17550
C17949_C17962    C19713_C19843    C20918_C20921
C20941_C20942    C20994_C20995    C21387_C21388
C21455_C21456    C21457_C21458    C21539_C21662
C21620_C21663    C21622_C21667    C21664_C21665
C22101_C22102    C22138_C22139    C22140_C22141
 » show all
Related class
Reaction
R00254 R00259 R00411 R00484 R00487 R00488 R00494 R00546
R00577 R00669 R00693 R00735 R00832 R00894 R00910 R00911
R00912 R00942 R01089 R01149 R01150 R01160 R01164 R01166
R01262 R01263 R01397 R01493 R01494 R01496 R01581 R01654
R01687 R01991 R01992 R02040 R02182 R02190 R02191 R02192
R02237 R02282 R02423 R02481 R02482 R02543 R02576 R02733
R02734 R02743 R02783 R02786 R02788 R03193 R03286 R03288
R03749 R03813 R03862 R03867 R03903 R03916 R03935 R03956
R03970 R04011 R04012 R04112 R04159 R04230 R04231 R04241
R04242 R04316 R04369 R04573 R04591 R04611 R04617 R04685
R04730 R04776 R04935 R04950 R05197 R05207 R05672 R05677
R05782 R06517 R06518 R06527 R06528 R07642 R07651 R08171
R08323 R08780 R08850 R08871 R08872 R08874 R08876 R08938
R09107 R09399 R09400 R09401 R09535 R09592 R09593 R09594
R09595 R09622 R09722 R09775 R09779 R09801 R09875 R10090
R10091 R10553 R10621 R10677 R10678 R10679 R10687 R10688
R10693 R10880 R10891 R10892 R10893 R10901 R10929 R10933
R10941 R10942 R10943 R10944 R10993 R11021 R11064 R11085
R11190 R11443 R11444 R11524 R11547 R11548 R11622 R11792
R11793 R11794 R11795 R11801 R11861 R11950 R12024 R12085
R12272 R12354 R12410 R12412 R12478 R12513 R12703 R13096
R13098
 » show all
Enzyme
2.1.3.2         2.1.3.16        2.3.1.1         2.3.1.14        
2.3.1.17        2.3.1.24        2.3.1.33        2.3.1.34        
2.3.1.35        2.3.1.36        2.3.1.53        2.3.1.66        
2.3.1.68        2.3.1.80        2.3.1.109       2.3.1.112       
2.3.1.183       2.3.1.189       2.3.1.266       2.3.1.267       
2.3.1.271       2.3.1.291       2.3.1.297       2.3.1.298       
2.3.1.299       2.3.1.321       2.3.1.-         2.3.2.1         
2.3.2.2         2.3.2.6         2.3.2.8         2.3.2.12        
2.3.2.14        2.3.2.15        2.3.2.29        2.3.2.30        
2.3.2.-         2.3.-.-         3.4.13.4        3.4.13.5        
3.4.13.18       3.4.13.20       3.4.13.22       3.4.14.13       
3.4.15.6        3.4.17.8        3.4.17.21       3.4.17.23       
3.4.19.9        3.4.19.13       3.4.19.14       3.4.19.16       
3.4.-.-         3.5.1.7         3.5.1.14        3.5.1.15        
3.5.1.16        3.5.1.18        3.5.1.23        3.5.1.28        
3.5.1.47        3.5.1.55        3.5.1.77        3.5.1.81        
3.5.1.82        3.5.1.83        3.5.1.87        3.5.1.96        
3.5.1.114       3.5.1.118       3.5.1.125       3.5.1.127       
3.5.1.128       3.5.1.130       3.5.1.132       3.5.1.133       
3.5.1.134       3.5.3.9         3.13.1.6        4.3.2.7         
4.3.2.9         6.3.1.17        6.3.2.2         6.3.2.4         
6.3.2.5         6.3.2.6         6.3.2.7         6.3.2.8         
6.3.2.9         6.3.2.10        6.3.2.11        6.3.2.12        
6.3.2.13        6.3.2.16        6.3.2.17        6.3.2.24        
6.3.2.25        6.3.2.29        6.3.2.30        6.3.2.31        
6.3.2.32        6.3.2.33        6.3.2.34        6.3.2.35        
6.3.2.38        6.3.2.39        6.3.2.41        6.3.2.42        
6.3.2.43        6.3.2.45        6.3.2.47        6.3.2.48        
6.3.2.49        6.3.2.51        6.3.2.52        6.3.2.53        
6.3.2.57        6.3.2.60        6.3.2.-
 » show all
Pathway
rn00220  Arginine biosynthesis
rn00230  Purine metabolism
rn00250  Alanine, aspartate and glutamate metabolism
rn00260  Glycine, serine and threonine metabolism
rn00261  Monobactam biosynthesis
rn00270  Cysteine and methionine metabolism
rn00300  Lysine biosynthesis
rn00330  Arginine and proline metabolism
rn00340  Histidine metabolism
rn00360  Phenylalanine metabolism
rn00410  beta-Alanine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00460  Cyanoamino acid metabolism
rn00470  D-Amino acid metabolism
rn00480  Glutathione metabolism
rn00550  Peptidoglycan biosynthesis
rn00590  Arachidonic acid metabolism
rn00600  Sphingolipid metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00904  Diterpenoid biosynthesis
rn00997  Biosynthesis of various other secondary metabolites
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM002  Carboxyl to amino conversion using protective N-acetyl group (basic amino acid synthesis)
Orthology
K00608  aspartate carbamoyltransferase [EC:2.1.3.2]
K00609  aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
K00610  aspartate carbamoyltransferase regulatory subunit
K00618  amino-acid N-acetyltransferase [EC:2.3.1.1]
K00619  amino-acid N-acetyltransferase [EC:2.3.1.1]
K00620  glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
K00673  arginine N-succinyltransferase [EC:2.3.1.109]
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K00682  gamma-glutamylcyclotransferase [EC:4.3.2.9]
K00684  leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
K00685  arginyl-tRNA---protein transferase [EC:2.3.2.8]
K01307  gamma-glutamyl hydrolase [EC:3.4.19.9]
K01437  aspartoacylase [EC:3.5.1.15]
K01438  acetylornithine deacetylase [EC:3.5.1.16]
K01439  succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
K01441  alkaline ceramidase [EC:3.5.1.23]
K01446  peptidoglycan recognition protein
K01447  N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01448  N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
K01449  cell wall hydrolase
K01587  phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01798  Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
K01922  phosphopantothenate---cysteine ligase (ATP) [EC:6.3.2.51]
K01923  phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
K01924  UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
K01925  UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
K01928  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K02083  allantoate deiminase [EC:3.5.3.9]
K03823  phosphinothricin acetyltransferase [EC:2.3.1.183]
K03825  L-phenylalanine/L-methionine N-acetyltransferase [EC:2.3.1.53 2.3.1.-]
K03894  N2-citryl-N6-acetyl-N6-hydroxylysine synthase [EC:6.3.2.38]
K03895  aerobactin synthase [EC:6.3.2.39]
K04709  very-long-chain ceramide synthase [EC:2.3.1.297]
K04710  sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K04711  dihydroceramidase [EC:3.5.1.-]
K05362  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
K05375  MbtH protein
K05526  succinylglutamate desuccinylase [EC:3.5.1.96]
K05604  beta-Ala-His dipeptidase [EC:3.4.13.20]
K05823  N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]
K05827  [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
K05831  [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
K05848  phytoceramidase [EC:3.5.1.-]
K06015  N-acyl-D-amino-acid deacylase [EC:3.5.1.81]
K06048  glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
K07008  gamma-glutamyl hercynylcysteine S-oxide hydrolase [EC:3.5.1.118]
K07232  glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]
K08660  cytosolic nonspecific dipeptidase [EC:3.4.13.18]
K11067  N-acetylglutamate synthase [EC:2.3.1.1]
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205  glutamate--cysteine ligase regulatory subunit
K11206  deaminated glutathione amidase [EC:3.5.1.128]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K12234  coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
K12348  acid ceramidase [EC:3.5.1.23]
K12349  neutral ceramidase [EC:3.5.1.23]
K12554  alanine adding enzyme [EC:2.3.2.-]
K12632  puromycin N-acetyltransferase [EC:2.3.-.-]
K12636  N-acetylpuromycin N-acetylhydrolase
K12911  phosphinothricin tripeptide synthetase PhsA
K12912  phosphinothricin tripeptide synthetase phsB [EC:6.2.1.67]
K12913  phosphinothricin tripeptide synthetase PhsC
K12915  phosphinothricin tripeptide acetyl hydrolase
K13037  L-alanine-L-anticapsin ligase [EC:6.3.2.49]
K13038  phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
K13282  cyanophycinase [EC:3.4.15.6]
K13713  fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K14506  jasmonic acid-amino synthetase [EC:6.3.2.52]
K14592  glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
K14677  aminoacylase [EC:3.5.1.14]
K14681  argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1]
K14682  amino-acid N-acetyltransferase [EC:2.3.1.1]
K14755  carnosine synthase [EC:6.3.2.11]
K14940  gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
K15740  tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
K15784  N2-acetyl-L-2,4-diaminobutanoate deacetylase [EC:3.5.1.125]
K15792  MurE/MurF fusion protein [EC:6.3.2.13 6.3.2.10]
K18309  aspartate N-acetyltransferase [EC:2.3.1.17]
K18310  beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41]
K18311  N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18852  D-amino-acid N-acetyltransferase [EC:2.3.1.36]
K19102  nocardicin nonribosomal peptide synthetase NocA
K19103  nocardicin nonribosomal peptide synthetase NocB
K19111  putative tabtoxin peptidase [EC:3.4.-.-]
K19112  L-Amino acid ligase [EC:6.3.2.-]
K19113  acetyltransferase [EC:2.3.1.-]
K19412  glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
K20457  dihydrofolate synthase [EC:6.3.2.12]
K20838  N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-]
K21140  [CysO sulfur-carrier protein]-S-L-cysteine hydrolase [EC:3.13.1.6]
K21419  arginyl-tRNA---protein transferase [EC:2.3.2.8]
K21420  leucyl-tRNA---protein transferase [EC:2.3.2.29]
K21604  jasmonoyl-L-amino acid hydrolase [EC:3.5.1.127]
K21977  phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K22114  dapdiamide synthase [EC:6.3.2.47]
K22310  L-ornithine Nalpha-acyltransferase [EC:2.3.2.30]
K22314  glucosinolate gamma-glutamyl hydrolase [EC:3.4.19.16]
K22476  N-acetylglutamate synthase [EC:2.3.1.1]
K22477  N-acetylglutamate synthase [EC:2.3.1.1]
K22478  bifunctional N-acetylglutamate synthase/kinase [EC:2.3.1.1 2.7.2.8]
K22596  gamma-glutamylcyclotransferase, plant [EC:4.3.2.9]
K22842  L-glutamate-5-semialdehyde N-acetyltransferase [EC:2.3.1.271]
K23169  UDP-N-acetylmuramoyl-L-alanine---L-glutamate ligase [EC:6.3.2.53]
K23447  staphyloferrin A synthase [EC:6.3.2.57]
K23672  L-propargylglycine--L-glutamate ligase [EC:6.3.2.-]
K23727  sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K24102  dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
K24621  very-long-chain ceramide synthase [EC:2.3.1.297]
K24622  very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K24871  ureidoglycine carbamoyltransferase [EC:2.1.3.16]
K24998  dehydro coenzyme F420 reductase / coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:1.3.8.17 6.3.2.31 6.3.2.34]
K25032  alpha-aminoadipate-LysW ligase/glutamate-LysW ligase [EC:6.3.2.43 6.3.2.60]
K26272  D-glutamate N-acetyltransferase [EC:2.3.1.312]
K27850  3'-N-debenzoyltaxol N-benzoyltransferase [EC:2.3.1.321]
K28194  very-long-chain ceramide synthase [EC:2.3.1.297]
K28195  ceramide synthase [EC:2.3.1.291]

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