KEGG   PATHWAY: slal04810
Entry
slal04810                   Pathway                                
Name
Regulation of actin cytoskeleton - Seriola lalandi dorsalis (Yellowtail amberjack)
Class
Cellular Processes; Cell motility
Pathway map
slal04810  Regulation of actin cytoskeleton
slal04810

Other DBs
GO: 0030036
Organism
Seriola lalandi dorsalis (Yellowtail amberjack) [GN:slal]
Gene
111644184  [KO:K05704] [EC:2.7.10.2]
111644345  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
111644568  rgcc; regulator of cell cycle RGCC [KO:K26108]
111644604  nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
111644609  [KO:K03996]
111644654  fgf2; fibroblast growth factor 2 [KO:K18497]
111644663  [KO:K04358]
111644702  [KO:K12753]
111644710  [KO:K05767]
111644857  [KO:K10352]
111644951  [KO:K04362] [EC:2.7.10.1]
111644953  [KO:K05760]
111645255  [KO:K03916]
111645313  [KO:K04456] [EC:2.7.11.1]
111645396  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
111645811  [KO:K04347]
111646092  [KO:K05768]
111646431  [KO:K05763]
111646443  [KO:K04358]
111646540  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
111646633  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
111646663  [KO:K04358]
111646815  [KO:K08007]
111646819  fgfr3; fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
111646879  f2; prothrombin [KO:K01313] [EC:3.4.21.5]
111647195  [KO:K17260]
111647380  [KO:K04361] [EC:2.7.10.1]
111647451  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
111647479  [KO:K05743] [EC:2.7.11.1]
111647584  [KO:K05692]
111647650  mylk; myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
111647742  bcar1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726]
111647878  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
111647905  [KO:K10351]
111647945  [KO:K08845] [EC:2.7.11.1]
111648041  fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
111648147  pdgfc; platelet-derived growth factor C [KO:K05450]
111648180  egf; pro-epidermal growth factor [KO:K04357]
111648187  diaph2; protein diaphanous homolog 2 [KO:K05741]
111648245  vav3; guanine nucleotide exchange factor VAV3 [KO:K05730]
111648309  [KO:K06485]
111648408  [KO:K05754]
111649083  [KO:K07827]
111649228  [KO:K12753]
111649440  [KO:K03916]
111649465  [KO:K05742]
111649932  [KO:K02649]
111650054  pfn2; profilin-2 isoform X1 [KO:K05759]
111650106  [KO:K00889] [EC:2.7.1.68]
111650129  [KO:K05768]
111650530  ezr; ezrin [KO:K05762]
111650572  wasf1; wiskott-Aldrich syndrome protein family member 1 isoform X1 [KO:K05753]
111650706  [KO:K04410] [EC:2.7.11.1]
111650904  [KO:K00889] [EC:2.7.1.68]
111650934  [KO:K05743] [EC:2.7.11.1]
111651017  [KO:K06269] [EC:3.1.3.16]
111651178  [KO:K18584]
111651267  [KO:K04132]
111651354  [KO:K05692]
111651358  [KO:K12753]
111651451  [KO:K02649]
111651520  [KO:K04358]
111651770  slc9a1; sodium/hydrogen exchanger 1 [KO:K05742]
111651948  [KO:K05759]
111652032  [KO:K26108]
111652184  itga10; integrin alpha-10 [KO:K06586]
111652192  [KO:K05627]
111652244  [KO:K06269] [EC:3.1.3.16]
111652253  [KO:K12758]
111652357  [KO:K04409] [EC:2.7.11.1]
111652444  pak6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
111652514  [KO:K04410] [EC:2.7.11.1]
111652554  itgb6; integrin beta-6 [KO:K06589]
111652560  [KO:K05717]
111652614  [KO:K04369] [EC:2.7.12.2]
111652622  arhgef12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
111652698  [KO:K18496]
111652779  itga8; integrin alpha-8 [KO:K06584]
111652838  [KO:K04358]
111652941  egfr; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
111652992  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
111653269  rock1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
111653387  [KO:K17388] [EC:2.7.11.39]
111653396  ins; insulin [KO:K04526]
111653428  sos1; son of sevenless homolog 1 [KO:K03099]
111653687  [KO:K04291]
111653776  pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
111653880  [KO:K05765]
111653956  [KO:K05732]
111653974  [KO:K04456] [EC:2.7.11.1]
111654079  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
111654088  itgb5; integrin beta-5 [KO:K06588]
111654148  [KO:K05759]
111654176  [KO:K04393]
111654345  arhgef7; rho guanine nucleotide exchange factor 7 [KO:K13710]
111654503  rras2; ras-related protein R-Ras2 [KO:K07830]
111654894  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
111654900  fgf10; fibroblast growth factor 10 [KO:K04358]
111654928  itga2; integrin alpha-2 [KO:K06481]
111654949  fgd1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720]
111654989  [KO:K12329]
111655057  [KO:K06587]
111655245  dock1; dedicator of cytokinesis protein 1 isoform X1 [KO:K13708]
111655272  pdgfd; platelet-derived growth factor D [KO:K05450]
111655355  kras; GTPase KRas isoform X1 [KO:K07827]
111655614  rras; ras-related protein R-Ras [KO:K07830]
111655640  crkl; crk-like protein [KO:K04438]
111655805  [KO:K05765]
111655888  [KO:K05730]
111655943  [KO:K04289]
111655946  vav2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
111656009  arhgap35; rho GTPase-activating protein 35 [KO:K05732]
111656071  [KO:K04438]
111656293  [KO:K17388] [EC:2.7.11.39]
111656372  map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
111656442  git1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
111656449  ssh2; protein phosphatase Slingshot homolog 2 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
111656567  fam49b; protein FAM49B [KO:K27976]
111656573  [KO:K12757]
111656615  iqgap1; ras GTPase-activating-like protein IQGAP1 [KO:K16848]
111656795  itga1; integrin alpha-1 [KO:K06480]
111656890  [KO:K05735] [EC:2.7.11.1]
111657005  [KO:K12757]
111657078  itgb3; integrin beta-3 isoform X1 [KO:K06493]
111657104  vcl; vinculin isoform X1 [KO:K05700]
111657114  [KO:K00907] [EC:2.7.11.18]
111657213  [KO:K05725] [EC:2.7.10.2]
111657270  arhgef1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
111657398  [KO:K03916]
111657402  [KO:K03916]
111657410  [KO:K03916]
111657412  [KO:K03916]
111657469  [KO:K04358]
111657524  [KO:K06476]
111657570  [KO:K00889] [EC:2.7.1.68]
111657703  [KO:K04371] [EC:2.7.11.24]
111657761  [KO:K05627]
111657801  [KO:K05731]
111657862  brk1; protein BRICK1 [KO:K05752]
111657969  [KO:K05734] [EC:2.7.11.1]
111657978  actn4; alpha-actinin-4 isoform X1 [KO:K05699]
111658169  [KO:K10031]
111658188  [KO:K05700]
111658296  msn; moesin isoform X1 [KO:K05763]
111658453  [KO:K06493]
111658565  fgf16; fibroblast growth factor 16 [KO:K04358]
111658620  fgf21; fibroblast growth factor 21 [KO:K22429]
111658703  [KO:K06461]
111658866  [KO:K04513]
111658892  [KO:K00889] [EC:2.7.1.68]
111658940  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
111658968  itga9; integrin alpha-9 [KO:K06585]
111659362  wasf2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
111659458  [KO:K04456] [EC:2.7.11.1]
111659477  [KO:K07830]
111659520  itgav; LOW QUALITY PROTEIN: integrin alpha-V [KO:K06487]
111659550  [KO:K05751]
111659677  [KO:K10352]
111659755  [KO:K10352]
111659838  [KO:K05719]
111659966  fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
111659975  [KO:K12756]
111660016  fgf23; fibroblast growth factor 23 [KO:K22428]
111660017  [KO:K04358]
111660032  ppp1r12a; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
111660037  chrm2; muscarinic acetylcholine receptor M2 [KO:K04130]
111660176  cyfip1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
111660247  [KO:K00889] [EC:2.7.1.68]
111660256  limk2; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
111660315  iqgap2; ras GTPase-activating-like protein IQGAP2 isoform X1 [KO:K05767]
111660342  f2r; proteinase-activated receptor 1 [KO:K03914]
111660345  ssh1; protein phosphatase Slingshot homolog 1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
111660400  [KO:K05718]
111660406  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
111660421  [KO:K17457]
111660426  [KO:K05718]
111660545  [KO:K06269] [EC:3.1.3.16]
111660567  [KO:K12758]
111660594  [KO:K00907] [EC:2.7.11.18]
111660679  src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
111660814  [KO:K04513]
111660943  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
111660967  fgf5; fibroblast growth factor 5 [KO:K04358]
111661096  [KO:K00907] [EC:2.7.11.18]
111661121  fgf7; fibroblast growth factor 7 [KO:K04358]
111661236  [KO:K04347]
111661259  [KO:K05768]
111661265  [KO:K00922] [EC:2.7.1.153]
111661385  [KO:K17388] [EC:2.7.11.39]
111661495  [KO:K08007]
111661496  [KO:K06269] [EC:3.1.3.16]
111661522  chrm5; muscarinic acetylcholine receptor M5 [KO:K04133]
111661555  enah; protein enabled homolog [KO:K05746]
111661823  hras; GTPase HRas [KO:K02833]
111661895  [KO:K06484]
111662009  actr2; actin-related protein 2 isoform X1 [KO:K17260]
111662084  tmsb4x; thymosin beta-4 [KO:K05764]
111662291  [KO:K04513]
111662376  ptk2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
111662461  [KO:K10352]
111662481  [KO:K10352]
111662594  [KO:K05768]
111662606  [KO:K04347]
111662758  diaph1; protein diaphanous homolog 1 isoform X1 [KO:K05740]
111662888  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
111662895  [KO:K05769]
111662985  c8g; complement component C8 gamma chain [KO:K03999]
111663115  [KO:K04133]
111663289  gna12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
111663292  [KO:K05757]
111663305  [KO:K05757]
111663445  [KO:K18584]
111663462  [KO:K04358]
111663463  [KO:K06464]
111663602  [KO:K04358]
111663662  [KO:K23612]
111663742  [KO:K04131]
111664218  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
111664301  [KO:K04131]
111664334  rac3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
111664381  [KO:K05627]
111664470  [KO:K04362] [EC:2.7.10.1]
111664630  [KO:K04526]
111664638  [KO:K05764]
111664651  [KO:K05749]
111664875  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
111665087  [KO:K23612]
111665237  [KO:K18584]
111665269  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
111665334  [KO:K13710]
111665347  [KO:K05764]
111665361  [KO:K06269] [EC:3.1.3.16]
111665370  [KO:K05762]
111665388  [KO:K06482]
111665447  [KO:K04456] [EC:2.7.11.1]
111665471  [KO:K04362] [EC:2.7.10.1]
111665495  arhgef4; rho guanine nucleotide exchange factor 4 isoform X1 [KO:K05769]
111665502  mos; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
111665567  [KO:K10031]
111665702  [KO:K04393]
111665788  itga4; integrin alpha-4 [KO:K06483]
111665874  [KO:K04410] [EC:2.7.11.1]
111665903  sos2; son of sevenless homolog 2 [KO:K03099]
111665914  actn1; alpha-actinin-1 isoform X1 [KO:K05699]
111666059  [KO:K22428]
111666097  [KO:K04358]
111666241  [KO:K05733] [EC:2.7.11.1]
111666346  [KO:K05729]
111666387  [KO:K04513]
111666488  c8a; complement component C8 alpha chain [KO:K03997]
111666489  c8b; complement component C8 beta chain [KO:K03998]
111666497  [KO:K04189]
111666638  [KO:K04358]
111666716  myh11; myosin-11 isoform X1 [KO:K10352]
111666761  [KO:K03914]
111666768  c9; complement component C9 [KO:K04000]
111666834  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
111666970  [KO:K06270]
111667016  map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
111667085  itgb4; integrin beta-4 [KO:K06525]
111667200  [KO:K04639]
111667247  [KO:K05757]
111667451  mras; ras-related protein M-Ras [KO:K07831]
111667536  [KO:K04392]
111667551  pdgfa; platelet-derived growth factor subunit A [KO:K04359]
111667708  [KO:K23612]
111667728  [KO:K05755]
111667752  [KO:K12755]
111667829  [KO:K00920] [EC:2.7.1.149]
111668360  [KO:K05745]
111668384  [KO:K04189]
111668415  [KO:K05719]
111668527  itga6; integrin alpha-6 isoform X1 [KO:K06485]
111668547  c5; complement C5 [KO:K03994]
111668623  [KO:K04393]
111668658  [KO:K06484]
111668748  cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
111668768  [KO:K05717]
111668872  [KO:K04275]
111668884  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
111669019  [KO:K04513]
111669021  [KO:K04513]
111669267  fgf4; fibroblast growth factor 4 [KO:K04358]
111669279  fgf3; fibroblast growth factor 3 [KO:K04358]
111669309  fgf19; fibroblast growth factor 19 [KO:K22603]
111669341  c6; complement component C6 isoform X1 [KO:K03995]
111669342  [KO:K03996]
111669451  fgf8; fibroblast growth factor 8 isoform X1 [KO:K04358]
111669454  [KO:K05765]
111669615  [KO:K04132]
111669926  [KO:K04393]
111670134  itga11; integrin alpha-11 [KO:K06587]
111670176  nckap1l; nck-associated protein 1-like [KO:K05750]
111670186  itga7; integrin alpha-7 isoform X1 [KO:K06583]
111670241  apc; adenomatous polyposis coli protein isoform X1 [KO:K02085]
111670329  abi2; abl interactor 2 isoform X1 [KO:K05751]
111670361  chrm4; muscarinic acetylcholine receptor M4 [KO:K04132]
111670459  [KO:K06269] [EC:3.1.3.16]
111670553  [KO:K02649]
111670636  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
111670903  [KO:K10351]
111670942  [KO:K05760]
111670949  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
111671089  [KO:K02649]
111671107  [KO:K06485]
111671142  [KO:K05089] [EC:2.7.10.1]
111671210  [KO:K04130]
111671297  [KO:K04438]
111671597  pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
111671636  [KO:K02085]
111671654  [KO:K00922] [EC:2.7.1.153]
111671655  [KO:K03898]
111671734  [KO:K00907] [EC:2.7.11.18]
111671871  [KO:K07860]
111672005  rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
111672042  itga3; integrin alpha-3 [KO:K06482]
111672059  [KO:K18496]
111672131  [KO:K04526]
111672203  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
111672205  fgd3; FYVE, RhoGEF and PH domain-containing protein 3 [KO:K05722]
111672631  [KO:K27976]
111672671  pak5; serine/threonine-protein kinase PAK 5 isoform X1 [KO:K05736] [EC:2.7.11.1]
111672889  [KO:K17260]
111672948  vav1; proto-oncogene vav isoform X1 [KO:K05730]
111673001  actb; actin, cytoplasmic 1 [KO:K05692]
111673222  [KO:K07532]
111673263  akt1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
111673318  [KO:K27976]
111673426  [KO:K04359]
111673433  [KO:K04291]
111673435  [KO:K17386]
111673547  [KO:K04639]
111673607  [KO:K00922] [EC:2.7.1.153]
111673732  [KO:K17388] [EC:2.7.11.39]
111673833  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
slal04010  MAPK signaling pathway
slal04510  Focal adhesion
slal04520  Adherens junction
KO pathway
ko04810   

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