KEGG   PATHWAY: sjo04140
Entry
sjo04140                    Pathway                                
Name
Autophagy - animal - Scomber japonicus (chub mackerel)
Description
Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily conserved among eukaryotes and exquisitely regulated. This progress initiates with production of the autophagosome, a double-membrane intracellular structure of reticular origin that engulfs cytoplasmic contents and ultimately fuses with lysosomes for cargo degradation. Autophagy is regulated in response to extra- or intracellular stress and signals such as starvation, growth factor deprivation and ER stress. Constitutive level of autophagy plays an important role in cellular homeostasis and maintains quality control of essential cellular components.
Class
Cellular Processes; Transport and catabolism
Pathway map
sjo04140  Autophagy - animal
sjo04140

Other DBs
GO: 0006914
Organism
Scomber japonicus (chub mackerel) [GN:sjo]
Gene
128363077  insb; preproinsulin b [KO:K04526]
128371064  insulin [KO:K04526]
128371442  insulin-like [KO:K04526]
128358344  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
128356204  igf1rb; insulin-like growth factor 1b receptor [KO:K05087] [EC:2.7.10.1]
128370926  si:ch211-284e13.4; insulin receptor substrate 1-B [KO:K16172]
128383280  si:ch73-335l21.1; insulin receptor substrate 1-B isoform X1 [KO:K16172]
128368244  irs2b; insulin receptor substrate 2 [KO:K07187]
128354057  insulin receptor substrate 2-like [KO:K07187]
128384229  insulin receptor substrate 2-A isoform X1 [KO:K07187]
128368727  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128360701  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
128361329  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128384054  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128357418  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
128362253  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128362334  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128368529  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128369279  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
128380785  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
128381694  pdpk1b; 3-phosphoinositide dependent protein kinase 1b [KO:K06276] [EC:2.7.11.1]
128374961  akt3b; LOW QUALITY PROTEIN: RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128375416  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128360590  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128371932  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
128372947  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128381593  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
128372599  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
128359229  hrasa; HRas proto-oncogene, GTPase a [KO:K02833]
128358543  kras; GTPase KRas isoform X1 [KO:K07827]
128378744  zgc:55558; GTPase KRas isoform X1 [KO:K07827]
128367963  ras-related protein M-Ras [KO:K07831]
128363969  rras2; ras-related protein R-Ras2 [KO:K07830]
128378255  rras; ras-related protein R-Ras [KO:K07830]
128357963  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
128359279  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
128361721  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
128364483  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
128378997  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
128375915  hif1aa; hypoxia inducible factor 1 subunit alpha a [KO:K08268]
128381573  epas1a; endothelial PAS domain-containing protein 1 [KO:K08268]
128360708  hif1al; hypoxia inducible factor 1 subunit alpha, like isoform X1 [KO:K08268]
128381378  ddit4; DNA damage-inducible transcript 4 protein [KO:K08270]
128373022  DNA damage-inducible transcript 4 protein-like [KO:K08270]
128381140  tsc2; tuberin isoform X1 [KO:K07207]
128380427  tsc1b; TSC complex subunit 1b [KO:K07206]
128354708  hamartin-like [KO:K07206]
128380196  zgc:73226; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 [KO:K15464]
128372494  bnip4; BCL2 interacting protein 4 [KO:K15464]
128368934  rheb; GTP-binding protein Rheb [KO:K07208]
128356059  rhebl1; ras homolog, mTORC1 binding like 1 [KO:K07208]
128367812  rptor; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
128355207  si:dkeyp-97e7.9; LOW QUALITY PROTEIN: DEP domain-containing mTOR-interacting protein [KO:K20402]
128366806  deptor; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
128356865  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
128378941  akt1s1; uncharacterized protein akt1s1 [KO:K16184]
128381275  mlst8; target of rapamycin complex subunit lst8 [KO:K08266]
128371140  rps6kb1a; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
128371485  ribosomal protein S6 kinase beta-2-like [KO:K04688] [EC:2.7.11.1]
128360431  rps6kb1b; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
128363485  igbp1; immunoglobulin-binding protein 1 [KO:K17606]
128362526  serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like [KO:K04382] [EC:3.1.3.16]
128364625  serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
128371956  ppp2cab; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
128380210  ulk1b; serine/threonine-protein kinase ULK1 [KO:K21357] [EC:2.7.11.1]
128364485  ulk1a; serine/threonine-protein kinase ULK1a [KO:K21357] [EC:2.7.11.1]
128360241  ulk2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
128354381  atg13; autophagy-related protein 13 [KO:K08331]
128371235  atg101; autophagy-related protein 101 [KO:K19730]
128368871  rb1cc1; RB1-inducible coiled-coil protein 1 isoform X1 [KO:K17589]
128362493  atg2a; autophagy-related protein 2 homolog A [KO:K17906]
128375167  autophagy-related protein 2 homolog B-like [KO:K17906]
128380947  WD repeat domain phosphoinositide-interacting protein 1-like [KO:K17908]
128378249  wipi1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908]
128378898  wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
128380176  wdr45; LOW QUALITY PROTEIN: WD repeat domain phosphoinositide-interacting protein 4 [KO:K22991]
128381770  wdr45b; WD repeat domain phosphoinositide-interacting protein 3 [KO:K22991]
128368574  atg9b; autophagy-related protein 9B [KO:K17907]
128375502  atg9a; autophagy-related protein 9A [KO:K17907]
128371480  supt20; transcription factor SPT20 homolog isoform X1 [KO:K21245]
128377398  smcr8b; guanine nucleotide exchange protein smcr8b [KO:K23611]
128379036  smcr8a; guanine nucleotide exchange protein smcr8a [KO:K23611]
128379772  wdr41; WD repeat-containing protein 41 [KO:K23610]
128375514  c9orf72; guanine nucleotide exchange factor C9orf72 homolog [KO:K23609]
128368612  ras-related protein Rab-8A-like [KO:K07901]
128361661  ras-related protein Rab-8A [KO:K07901]
128374738  rab42a; ras-related protein Rab-42a [KO:K07925]
128371270  ras-related protein Rab-39B-like [KO:K07925]
128383719  ras-related protein Rab-39B [KO:K07925]
128362915  sqstm1; sequestosome-1 isoform X1 [KO:K14381]
128385125  tbk1; LOW QUALITY PROTEIN: serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
128367890  tank; TRAF family member-associated NF-kappa-B activator [KO:K12650]
128376922  ras-related protein ORAB-1 [KO:K07874]
128361001  ras-related protein ORAB-1-like [KO:K07874]
128372498  ras-related protein ORAB-1-like [KO:K07874]
128371913  rraga; ras-related GTP-binding protein A [KO:K16185]
128375103  rragd; ras-related GTP-binding protein D [KO:K16186]
128366586  rragca; ras-related GTP binding Ca [KO:K16186]
128373730  rragcb; ras-related GTP binding Cb [KO:K16186]
128368988  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
128380222  prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
128362104  prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 [KO:K07198] [EC:2.7.11.31]
128379546  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1 [KO:K04345] [EC:2.7.11.11]
128368523  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
128371365  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
128361373  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
128354994  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
128355592  prkcda; protein kinase C, delta a [KO:K06068] [EC:2.7.11.13]
128362500  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
128380720  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
128380895  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
128372422  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
128369151  bcl2b; apoptosis regulator Bcl-2 [KO:K02161]
128382756  apoptosis regulator Bcl-2-like [KO:K02161]
128355487  bcl-2-like protein 1 [KO:K04570]
128357296  bcl2l1; bcl-2-like protein 1 [KO:K04570]
128383316  badb; BCL2 associated agonist of cell death b isoform X1 [KO:K02158]
128380872  becn1; beclin-1 isoform X1 [KO:K08334]
128381707  nrbf2b; nuclear receptor-binding factor 2b [KO:K21246]
128366600  pik3r4; phosphoinositide 3-kinase regulatory subunit 4 [KO:K08333] [EC:2.7.11.1]
128383697  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
128375589  atg14; beclin 1-associated autophagy-related key regulator [KO:K17889]
128358736  ambra1b; activating molecule in BECN1-regulated autophagy protein 1B isoform X1 [KO:K17985]
128382417  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
128356968  uncharacterized protein LOC128356968 isoform X1 [KO:K21247]
128362128  si:ch211-260e23.9; tumor protein p53-inducible nuclear protein 2 [KO:K21247]
128360240  vmp1; vacuole membrane protein 1 [KO:K21248]
128371353  vacuole membrane protein 1-like isoform X1 [KO:K21248]
128367122  stx17; syntaxin-17 [KO:K08491]
128371177  uvrag; UV radiation resistance-associated gene protein [KO:K21249]
128375861  endophilin-B1-like [KO:K11248]
128382540  sh3glb1a; endophilin-B1a [KO:K11248]
128361744  rubcn; run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 [KO:K19330]
128380574  calcium/calmodulin-dependent protein kinase kinase 2 [KO:K07359] [EC:2.7.11.17]
128375393  mitogen-activated protein kinase kinase kinase 7-like isoform X1 [KO:K04427] [EC:2.7.11.25]
128376681  map3k7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
128379936  ern2; serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
128378775  serine/threonine-protein kinase/endoribonuclease IRE1-like [KO:K08852] [EC:2.7.11.1 3.1.26.-]
128354948  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
128355062  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
128358714  dapk2b; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
128369530  dapk3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
128354762  dapk2a; death-associated protein kinase 2a [KO:K08803] [EC:2.7.11.1]
128365381  dapk1; death-associated protein kinase 1 [KO:K08803] [EC:2.7.11.1]
128373635  si:dkey-240h12.4; death-associated protein kinase 2 [KO:K08803] [EC:2.7.11.1]
128360132  hmgb1b; high mobility group protein B1b [KO:K10802]
128371343  hmgb1a; high mobility group protein B1a [KO:K10802]
128375933  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [KO:K08860] [EC:2.7.11.1]
128375402  eif2ak4; eIF-2-alpha kinase GCN2 [KO:K16196] [EC:2.7.11.1]
128376664  eif2s1b; eukaryotic translation initiation factor 2 subunit 1b [KO:K03237]
128365470  mtmr3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
128371934  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
128356302  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
128375199  zinc finger FYVE domain-containing protein 1-like [KO:K17603]
128360200  si:ch211-11n16.2; zinc finger FYVE domain-containing protein 1 [KO:K17603]
128377395  zfyve1; zinc finger FYVE domain-containing protein 1 [KO:K17603]
128365887  atg12; ubiquitin-like protein ATG12 [KO:K08336]
128365742  atg5; autophagy protein 5 [KO:K08339]
128360928  atg16l1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
128360287  protein Atg16l2 [KO:K20868]
128355017  atg7; ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
128369122  atg10; ubiquitin-like-conjugating enzyme ATG10 [KO:K17888]
128354149  atg3; ubiquitin-like-conjugating enzyme ATG3 isoform X1 [KO:K08343]
128367554  CASP8 and FADD-like apoptosis regulator [KO:K04724]
128363340  rab33ba; RAB33B, member RAS oncogene family a [KO:K07920]
128380485  ras-related protein Rab-33B-like [KO:K07920]
128367955  zgc:101559; ras-related protein Rab-33B-like isoform X1 [KO:K07920]
128353450  prkcq; protein kinase C theta type [KO:K18052] [EC:2.7.11.13]
128358838  gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
128355156  gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
128355165  gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
128365888  zgc:92606; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
128383872  gabarapa; GABA(A) receptor-associated protein a [KO:K08341]
128362779  map1lc3cl; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
128358724  map1lc3b; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
128355548  map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
128378427  map1lc3c; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
128374628  atg4da; cysteine protease atg4da [KO:K08342] [EC:3.4.22.-]
128378454  cysteine protease atg4da-like [KO:K08342] [EC:3.4.22.-]
128361654  atg4b; cysteine protease ATG4B isoform X1 [KO:K08342] [EC:3.4.22.-]
128361695  atg4c; cysteine protease ATG4C [KO:K08342] [EC:3.4.22.-]
128379625  nbr1b; next to BRCA1 gene 1 protein isoform X1 [KO:K17987]
128381352  nbr1a; NBR1 autophagy cargo receptor a [KO:K17987]
128353366  optn; optineurin isoform X1 [KO:K19946]
128381437  calcium-binding and coiled-coil domain-containing protein 2-like isoform X1 [KO:K21348]
128374315  tax1bp1a; tax1-binding protein 1 homolog A [KO:K21347]
128365995  tax1bp1b; tax1-binding protein 1 homolog B [KO:K21347]
128364440  wdfy3; LOW QUALITY PROTEIN: WD repeat and FYVE domain-containing protein 3 [KO:K22262]
128361571  uba52; ubiquitin-60S ribosomal protein L40 [KO:K02927]
128373195  rps27a; ubiquitin-40S ribosomal protein S27a [KO:K02977]
128364540  snap29; synaptosomal-associated protein 29 [KO:K08509]
128380299  si:ch73-234b20.5; vesicle-associated membrane protein 8 isoform X1 [KO:K08512]
128364975  vesicle-associated membrane protein 8-like [KO:K08512]
128365486  vamp8; vesicle-associated membrane protein 8 [KO:K08512]
128365388  ykt6; synaptobrevin homolog YKT6 [KO:K08516]
128376763  stx7l; syntaxin-7 [KO:K08488]
128364589  epg5; ectopic P granules protein 5 homolog [KO:K23883]
128381916  plekhm1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
128371683  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
128354256  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
128377394  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
128364566  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
128375555  vps39; vam6/Vps39-like protein [KO:K20183]
128373336  birc6; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6 [KO:K10586] [EC:2.3.2.23]
128368370  Golgi reassembly-stacking protein 2-like [KO:K26797]
128369266  gorasp1a; Golgi reassembly-stacking protein 1a [KO:K26797]
128369368  Golgi reassembly-stacking protein 2-like [KO:K26797]
128382615  Golgi reassembly-stacking protein 1-like [KO:K26797]
128355071  si:dkey-13a21.4; ras-related protein rab7 isoform X1 [KO:K07897]
128355188  ras-related protein rab7 [KO:K07897]
128355517  ras-related protein rab7-like [KO:K07897]
128362654  lamp2; lysosome-associated membrane glycoprotein 2 isoform X1 [KO:K06528]
128363030  lamp1a; lysosome-associated membrane glycoprotein 1a [KO:K06528]
128367773  lamp1b; lysosome-associated membrane glycoprotein 1b [KO:K06528]
128354927  ctsd; cathepsin D [KO:K01379] [EC:3.4.23.5]
128378464  napsa; napsin-A [KO:K01379] [EC:3.4.23.5]
128374921  ctsl.1; cathepsin L.1 [KO:K01365] [EC:3.4.22.15]
128364571  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
128365380  ctsla; cathepsin La [KO:K01365] [EC:3.4.22.15]
128361798  cts12; procathepsin L [KO:K01365] [EC:3.4.22.15]
128376995  ctsbb; cathepsin Bb [KO:K01363] [EC:3.4.22.1]
128356817  ctsba; cathepsin B [KO:K01363] [EC:3.4.22.1]
Compound
C00035  GDP
C00044  GTP
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15325584
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
DOI:10.1016/j.biocel.2004.02.002
Reference
PMID:16099218
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
DOI:10.1016/j.it.2005.08.003
Reference
PMID:16200202
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
DOI:10.1172/JCI26390
Reference
PMID:15325588
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
DOI:10.1016/j.biocel.2004.05.009
Reference
PMID:15928708
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
DOI:10.1038/nrm1660
Reference
PMID:15978794
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
DOI:10.1016/j.ceb.2005.06.007
Reference
PMID:11099404
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
DOI:10.1126/science.290.5497.1717
Reference
PMID:16125113
  Authors
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Int J Biochem Cell Biol 37:2098-114 (2005)
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Annu Rev Genet 43:67-93 (2009)
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An overview of the molecular mechanism of autophagy.
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Curr Top Microbiol Immunol 335:1-32 (2009)
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PMID:20034776
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Mammalian autophagy: core molecular machinery and signaling regulation.
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Curr Opin Cell Biol 22:124-31 (2010)
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PMID:21187343
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Chen Y, Klionsky DJ
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The regulation of autophagy - unanswered questions.
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J Cell Sci 124:161-70 (2011)
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The role of Atg proteins in autophagosome formation.
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Annu Rev Cell Dev Biol 27:107-32 (2011)
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Cell Res 24:42-57 (2014)
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Related
pathway
sjo04010  MAPK signaling pathway
sjo04141  Protein processing in endoplasmic reticulum
sjo04142  Lysosome
sjo04150  mTOR signaling pathway
sjo04910  Insulin signaling pathway
KO pathway
ko04140   
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