KEGG Orthology (KO) - Pongo abelii (Sumatran orangutan)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:pon05200]
     05202 Transcriptional misregulation in cancer [PATH:pon05202]
     05206 MicroRNAs in cancer [PATH:pon05206]
       100171828 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       100449905 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100440197 TIMP3; metalloproteinase inhibitor 3
       100462513 KRAS; GTPase KRas isoform X1
       100454924 CDK6; cyclin-dependent kinase 6
       100460228 CDC25A; M-phase inducer phosphatase 1 isoform X3
       100434256 CDC25B; M-phase inducer phosphatase 2 isoform X1
       100451443 CDC25C; M-phase inducer phosphatase 3 isoform X1
       100436170 HMGA2; high mobility group protein HMGI-C isoform X2
       100171625 CCND1; G1/S-specific cyclin-D1
       100457978 CCND2; G1/S-specific cyclin-D2
       100438282 CCNE2; G1/S-specific cyclin-E2 isoform X1
       100461587 CCNE1; G1/S-specific cyclin-E1 isoform X1
       100452410 CRK; adapter molecule crk isoform X1
       100443298 CRKL; crk-like protein
       100458256 HDAC5; histone deacetylase 5 isoform X1
       100440788 HDAC4; histone deacetylase 4 isoform X1
       100432353 FOXP1; forkhead box protein P1 isoform X7
       100461844 PIM1; serine/threonine-protein kinase pim-1
       100137030 MET; hepatocyte growth factor receptor precursor
       100459471 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
       100459992 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X1
       100436188 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1
       100442963 bcl-2-like protein 2 isoform X3
       100459280 EGFR; epidermal growth factor receptor isoform X2
       100448769 VEGFA; vascular endothelial growth factor A isoform X1
       100171534 ZEB1; zinc finger E-box-binding homeobox 1
       100461291 TGFB2; transforming growth factor beta-2 isoform X1
       100458178 EZR; ezrin isoform X1
       100173014 PDCD4; programmed cell death protein 4
       100455260 EP300; histone acetyltransferase p300 isoform X2
       100445634 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
       100172445 TPM1; tropomyosin alpha-1 chain
       100173576 SPRY2; protein sprouty homolog 2
       100938429 BCL2; apoptosis regulator Bcl-2 isoform X1
       100444556 SERPINB5; serpin B5
       100448596 ST14; suppressor of tumorigenicity 14 protein
       100172192 CYP1B1; cytochrome P450 1B1
       100456786 MTOR; serine/threonine-protein kinase mTOR
       100434731 RPTOR; regulatory-associated protein of mTOR isoform X1
       100457433 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
       100450307 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
       100174431 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor
       100453216 ABL1; tyrosine-protein kinase ABL1 isoform X1
       100444448 TP63; tumor protein 63 isoform X1
       100171900 ZEB2; zinc finger E-box-binding homeobox 2
       100439960 FSCN1; LOW QUALITY PROTEIN: fascin
       103888520 RASSF1; ras association domain-containing protein 1 isoform X3
       100174239 HOXD10; homeobox protein Hox-D10
       100445736 DDIT4; DNA damage-inducible transcript 4 protein
       100454976 BMF; bcl-2-modifying factor isoform X3
       100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
       100455867 MMP9; LOW QUALITY PROTEIN: matrix metalloproteinase-9
       100459572 SLC7A1; high affinity cationic amino acid transporter 1
       100173395 CCNG1; cyclin-G1
       100173339 HMOX1; heme oxygenase 1
       100435715 STMN1; stathmin
       100171541 STAT3; signal transducer and activator of transcription 3
       100456735 MYC; myc proto-oncogene protein
       100435491 CASP3; caspase-3
       100459427 HRAS; GTPase HRas
       100174317 NRAS; GTPase NRas precursor
       100436978 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X1
       100431482 APC; adenomatous polyposis coli protein isoform X2
       100435472 APC2; adenomatous polyposis coli protein 2 isoform X1
       100442255 IRS1; insulin receptor substrate 1
       100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
       100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100451029 MAPK7; mitogen-activated protein kinase 7 isoform X1
       100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100173769 HNRNPK; heterogeneous nuclear ribonucleoprotein K
       100431403 RECK; reversion-inducing cysteine-rich protein with Kazal motifs isoform X1
       100448297 E2F3; transcription factor E2F3 isoform X3
       100452233 IRS2; insulin receptor substrate 2
       100449179 NOTCH1; neurogenic locus notch homolog protein 1
       100447628 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       100454773 NOTCH3; neurogenic locus notch homolog protein 3
       100436768 NOTCH4; neurogenic locus notch homolog protein 4
       100173052 BMI1; polycomb complex protein BMI-1
       100447086 MMP16; matrix metalloproteinase-16 isoform X1
       100451505 ATM; serine-protein kinase ATM isoform X1
       100445635 SOCS1; suppressor of cytokine signaling 1
       100172786 CD44; CD44 antigen precursor
       100462160 DICER1; endoribonuclease Dicer isoform X1
       100457942 FZD3; frizzled-3
       100453984 ITGA5; integrin alpha-5
       100453730 RDX; radixin isoform X2
       100171605 RHOA; transforming protein RhoA precursor
       100171578 PLAU; urokinase-type plasminogen activator precursor
       100460189 bcl-2 homologous antagonist/killer
       100432001 BAK1; bcl-2 homologous antagonist/killer isoform X1
       100444744 ZFPM2; zinc finger protein ZFPM2 isoform X1
       100445345 ITGB3; integrin beta-3
       100454750 UBE2I; SUMO-conjugating enzyme UBC9
       100449029 SOX4; transcription factor SOX-4
       100451868 TNC; tenascin isoform X4
       100443502 TNXB; LOW QUALITY PROTEIN: tenascin-X
       100452638 TNR; tenascin-R isoform X1
       100453010 TNN; tenascin-N isoform X1
       100452463 ABCB1; multidrug resistance protein 1
       100431822 ABCC1; multidrug resistance-associated protein 1
       100439533 BRCA1; breast cancer type 1 susceptibility protein isoform X5
       100453682 CDKN1A; cyclin-dependent kinase inhibitor 1
       100448360 EFNA1; ephrin-A1
       100448970 EFNA3; ephrin-A3 isoform X1
       100449916 EFNA4; ephrin-A4 isoform X2
       100451193 EFNA5; ephrin-A5
       112130075 EFNA2; ephrin-A2
       100453386 THBS1; thrombospondin-1
       100451737 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
       100446303 TRIM71; E3 ubiquitin-protein ligase TRIM71
       100461595 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100440586 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
       100436566 PTGS2; prostaglandin G/H synthase 2
       100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
       100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
       100434355 PRKCA; protein kinase C alpha type isoform X1
       100439900 PRKCB; protein kinase C beta type isoform X2
       100451563 PRKCG; protein kinase C gamma type
       100173972 GRB2; growth factor receptor-bound protein 2
       100433126 FGFR3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3
       100173967 RPS6KA5; ribosomal protein S6 kinase alpha-5
       100435218 TP53; cellular tumor antigen p53
       100171532 MDM2; E3 ubiquitin-protein ligase Mdm2
       100461293 MDM4; protein Mdm4
       100431735 PDGFRA; platelet-derived growth factor receptor alpha
       100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
       100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
       100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100450988 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100434331 SOS2; son of sevenless homolog 2 isoform X1
       100458733 SOS1; son of sevenless homolog 1 isoform X1
       100173225 SHC1; SHC-transforming protein 1
       100440212 PDGFA; platelet-derived growth factor subunit A isoform X1
       100431574 SHC4; SHC-transforming protein 4
       100460243 PDGFB; platelet-derived growth factor subunit B
       100460001 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       100461015 cyclin-dependent kinase inhibitor 2A
       100435851 E2F1; transcription factor E2F1
       100458002 E2F2; transcription factor E2F2 isoform X1
       100443209 BCL2L11; bcl-2-like protein 11 isoform X1
       100445187 MARCKS; myristoylated alanine-rich C-kinase substrate
       100441517 BMPR2; bone morphogenetic protein receptor type-2
       100172663 HDAC1; histone deacetylase 1
       100294534 HDAC2; histone deacetylase 2
       100447447 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
       100431592 GLS; glutaminase kidney isoform, mitochondrial isoform X1
       100453856 GLS2; glutaminase liver isoform, mitochondrial isoform X2
       100443901 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
       100431449 WNT3; proto-oncogene Wnt-3
       100448240 WNT3A; protein Wnt-3a isoform X1
       100445606 CDCA5; sororin
       100460820 KIF23; kinesin-like protein KIF23 isoform X1
       100432582 ROCK1; rho-associated protein kinase 1
       100440778 PRKCE; protein kinase C epsilon type
       100454606 SLC45A3; solute carrier family 45 member 3
       100936414 VIM; vimentin
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16866 TIMP3; metalloproteinase inhibitor 3
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K09299 ZEB1; zinc finger homeobox protein 1
K13376 TGFB2; transforming growth factor beta-2
K08007 EZR; ezrin
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K04381 STMN1; stathmin 1
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
     05205 Proteoglycans in cancer [PATH:pon05205]
     05204 Chemical carcinogenesis - DNA adducts [PATH:pon05204]
     05207 Chemical carcinogenesis - receptor activation [PATH:pon05207]
     05208 Chemical carcinogenesis - reactive oxygen species [PATH:pon05208]
     05203 Viral carcinogenesis [PATH:pon05203]
     05230 Central carbon metabolism in cancer [PATH:pon05230]
     05231 Choline metabolism in cancer [PATH:pon05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:pon05235]
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 26, 2024