KEGG   PATHWAY: biu04621
Entry
biu04621                    Pathway                                
Name
NOD-like receptor signaling pathway - Bos indicus (zebu cattle)
Description
Specific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains more than 20 members in mammals and plays a pivotal role in the recognition of intracellular ligands. NOD1 and NOD2, two prototypic NLRs, sense the cytosolic presence of the bacterial peptidoglycan fragments that escaped from endosomal compartments, driving the activation of NF-{kappa}B and MAPK, cytokine production and apoptosis. On the other hand, a different set of NLRs induces caspase-1 activation through the assembly of multiprotein complexes called inflammasomes. The activated of caspase-1 regulates maturation of the pro-inflammatory cytokines IL-1B, IL-18 and drives pyroptosis.
Class
Organismal Systems; Immune system
Pathway map
biu04621  NOD-like receptor signaling pathway
biu04621

Organism
Bos indicus (zebu cattle) [GN:biu]
Gene
109557478  nucleotide-binding oligomerization domain-containing protein 1-like [KO:K08727]
109557904  nucleotide-binding oligomerization domain-containing protein 1-like [KO:K08727]
109568588  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
109553086  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
109553353  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
109572576  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
109575581  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
109560296  NFKB1; LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p105 subunit [KO:K02580]
109554392  RELA; transcription factor p65 [KO:K04735]
109566133  IL1B; interleukin-1 beta [KO:K04519]
109569934  IL18; interleukin-18 isoform X1 [KO:K05482]
109558077  IL6; interleukin-6 [KO:K05405]
109577428  TNF; tumor necrosis factor [KO:K03156]
109560575  C-X-C motif chemokine 15-like isoform X1 [KO:K10030]
109560570  CXCL8; interleukin-8 [KO:K10030]
109560578  growth-regulated protein homolog beta-like [KO:K05505]
109560579  growth-regulated protein homolog beta [KO:K05505]
109560573  growth-regulated protein homolog gamma isoform X1 [KO:K05505]
109574464  C-C motif chemokine 2 [KO:K14624]
109574467  CCL5; C-C motif chemokine 5 [KO:K12499]
109575948  cathelicidin-5 [KO:K13916]
109575951  cathelicidin-2 [KO:K13916]
109575953  cathelicidin-3 [KO:K13916]
109575954  cathelicidin-1-like [KO:K13916]
109575955  cathelicidin-1 [KO:K13916]
109575968  cathelicidin-7 [KO:K13916]
109575975  cathelicidin-4 [KO:K13916]
109575985  LOW QUALITY PROTEIN: cathelicidin-6-like [KO:K13916]
109575889  cathelicidin-4-like [KO:K13916]
109575890  cathelicidin-4-like [KO:K13916]
109553384  beta-defensin 103A [KO:K23126]
109553284  beta-defensin 103A-like [KO:K23126]
109553283  beta-defensin 103A-like [KO:K23126]
109553286  beta-defensin 103A-like [KO:K23126]
109553291  beta-defensin 103A-like [KO:K23126]
109553494  beta-defensin 103-like [KO:K23126]
109572753  NOD2; nucleotide-binding oligomerization domain-containing protein 2 isoform X1 [KO:K10165]
109563902  MAP3K7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
109559827  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
109564026  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
109578667  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
109570973  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
109561331  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
109560650  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
109553773  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
109577010  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
109577419  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
109556235  JUN; transcription factor AP-1 [KO:K04448]
109556543  ATG16L1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
109563867  ATG5; autophagy protein 5 isoform X1 [KO:K08339]
109564625  ATG12; ubiquitin-like protein ATG12 [KO:K08336]
109572143  GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
109573765  GABARAP; gamma-aminobutyric acid receptor-associated protein [KO:K08341]
109559670  GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
109570234  MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
109567387  MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
109572278  MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
109566666  SUGT1; protein SGT1 homolog isoform X1 [KO:K12795]
109568382  sharpin [KO:K20894]
109567335  RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1 [KO:K10630] [EC:2.3.2.31]
109564780  RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 [KO:K11974] [EC:2.3.2.31]
109574989  CARD6; caspase recruitment domain-containing protein 6 [KO:K12797]
109578471  TRIP6; thyroid receptor-interacting protein 6 [KO:K12792]
109574825  ERBIN; erbin isoform X1 [KO:K12796]
109555878  baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
109568764  BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
109569840  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
109566626  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
109570606  TRAF5; TNF receptor-associated factor 5 [KO:K09849]
109565970  LOW QUALITY PROTEIN: TNF receptor-associated factor 6-like [KO:K03175] [EC:2.3.2.27]
109566586  CARD9; caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
109563985  TNFAIP3; tumor necrosis factor alpha-induced protein 3 [KO:K11859] [EC:3.4.19.12]
109567183  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
109575564  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
109559273  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
109570721  IKBKE; LOW QUALITY PROTEIN: inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
109567123  TANK; TRAF family member-associated NF-kappa-B activator isoform X1 [KO:K12650]
109572224  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
109562847  interferon alpha-H [KO:K05414]
109562638  interferon alpha-G-like [KO:K05414]
109562641  LOW QUALITY PROTEIN: interferon alpha-1-like [KO:K05414]
109562644  interferon alpha-F [KO:K05414]
109562652  interferon alpha-A [KO:K05414]
109562656  interferon alpha-H-like [KO:K05414]
109562659  interferon alpha-H-like [KO:K05414]
109562660  interferon alpha-H-like [KO:K05414]
109562665  interferon alpha-B-like [KO:K05414]
109562668  interferon alpha-2-like [KO:K05414]
109562670  interferon alpha-2-like [KO:K05414]
109562673  interferon alpha-3-like [KO:K05414]
109562852  interferon beta-2-like [KO:K05415]
109562853  interferon beta-1-like [KO:K05415]
109562855  interferon beta-1 [KO:K05415]
109562667  LOW QUALITY PROTEIN: interferon beta-3-like [KO:K05415]
109562671  interferon beta-2-like [KO:K05415]
109562674  interferon beta-2 [KO:K05415]
109562675  interferon beta-2-like [KO:K05415]
109569836  NLRX1; NLR family member X1 [KO:K12653]
109560620  ANTXR2; anthrax toxin receptor 2 [KO:K20909]
109566235  ANTXR1; anthrax toxin receptor 1 [KO:K20909]
109574454  NLRP1; NACHT, LRR and PYD domains-containing protein 1 isoform X1 [KO:K12798]
109578833  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
109570010  CASP1; caspase-1 [KO:K01370] [EC:3.4.22.36]
109577782  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
109567345  BCL2L1; bcl-2-like protein 1 [KO:K04570]
109565507  bcl-2-like protein 1 [KO:K04570]
109562776  CTSB; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
109561926  NLRP3; NACHT, LRR and PYD domains-containing protein 3 isoform X1 [KO:K12800]
109554443  PANX1; pannexin-1 [KO:K03443]
109571559  P2RX7; P2X purinoceptor 7 isoform X1 [KO:K05220]
109561012  TRPM2; transient receptor potential cation channel subfamily M member 2 isoform X1 [KO:K04977] [EC:3.6.1.13]
109565130  TRPM7; transient receptor potential cation channel subfamily M member 7 isoform X1 [KO:K04982] [EC:2.7.11.1]
109574348  TRPV2; transient receptor potential cation channel subfamily V member 2 [KO:K04971]
109554157  CASR; LOW QUALITY PROTEIN: extracellular calcium-sensing receptor [KO:K04612]
109563496  GPRC6A; LOW QUALITY PROTEIN: G-protein coupled receptor family C group 6 member A [KO:K04622]
109554384  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
109567852  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
109567854  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
109564927  PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
109576135  ITPR1; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
109558547  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
109576552  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
109562011  VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
109553821  VDAC2; voltage-dependent anion-selective channel protein 2 [KO:K15040]
109553397  VDAC3; voltage-dependent anion-selective channel protein 3 [KO:K15041]
109553778  MCU; calcium uniporter protein, mitochondrial [KO:K20858]
109570926  2'-5'-oligoadenylate synthase 3-like [KO:K14216] [EC:2.7.7.84]
109571283  OAS2; 2'-5'-oligoadenylate synthase 2 isoform X1 [KO:K14216] [EC:2.7.7.84]
109571284  2'-5'-oligoadenylate synthase 1-like [KO:K14216] [EC:2.7.7.84]
109570705  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
109574199  DHX33; putative ATP-dependent RNA helicase DHX33 isoform X1 [KO:K17820] [EC:5.6.2.6]
109557833  MFN1; mitofusin-1 [KO:K21356] [EC:3.6.5.-]
109570412  MFN2; LOW QUALITY PROTEIN: mitofusin-2 [KO:K06030] [EC:3.6.5.-]
109577264  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
109564762  RIPK3; receptor-interacting serine/threonine-protein kinase 3 isoform X1 [KO:K08847] [EC:2.7.11.1]
109559542  DNM1L; dynamin-1-like protein [KO:K17065] [EC:3.6.5.5]
109557381  NAMPT; nicotinamide phosphoribosyltransferase [KO:K03462] [EC:2.4.2.12]
109572735  cytochrome b-245 light chain [KO:K08009]
109555824  TXNIP; thioredoxin-interacting protein [KO:K20910]
109559518  TXN2; thioredoxin, mitochondrial [KO:K03671]
109563333  TXN; thioredoxin [KO:K03671]
109570463  NEK7; serine/threonine-protein kinase Nek7 isoform X1 [KO:K20876] [EC:2.7.11.34]
109575457  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
109577125  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
109577399  GPSM3; G-protein-signaling modulator 3 [KO:K15838]
109578320  MEFV; pyrin [KO:K12803]
109575656  PSTPIP1; proline-serine-threonine phosphatase-interacting protein 1 isoform X1 [KO:K12804]
109569521  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
109554562  FADD; FAS-associated death domain protein [KO:K02373]
109572109  NLRP12; NACHT, LRR and PYD domains-containing protein 12 [KO:K20865]
109575004  NAIP; baculoviral IAP repeat-containing protein 1 [KO:K12807]
109565964  NLRC4; NLR family CARD domain-containing protein 4 isoform X1 [KO:K12805]
109576388  PRKCD; protein kinase C delta type isoform X1 [KO:K06068] [EC:2.7.11.13]
109556817  guanylate-binding protein 2-like [KO:K20897]
109556091  guanylate-binding protein 2-like isoform X1 [KO:K20897]
109556079  guanylate-binding protein 5-like isoform X1 [KO:K20898]
109578927  gamma-interferon-inducible protein 16-like [KO:K20914]
109575375  TP53BP1; tumor suppressor p53-binding protein 1 isoform X1 [KO:K20915]
109576171  RHOA; transforming protein RhoA [KO:K04513]
109561489  PKN1; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
109556095  PKN2; serine/threonine-protein kinase N2 isoform X1 [KO:K23691] [EC:2.7.11.13]
109573771  YWHAE; 14-3-3 protein epsilon isoform X1 [KO:K06630]
109556080  guanylate-binding protein 1-like [KO:K20899]
109556088  guanylate-binding protein 4-like isoform X1 [KO:K20899]
109556818  guanylate-binding protein 7-like [KO:K20899]
109556081  guanylate-binding protein 4-like isoform X1 [KO:K20899]
109556083  guanylate-binding protein 4-like [KO:K20899]
109556087  guanylate-binding protein 6-like [KO:K20899]
109556092  guanylate-binding protein 1-like isoform X1 [KO:K20899]
109569831  caspase-13 isoform X1 [KO:K04394] [EC:3.4.22.57 3.4.22.64]
109568375  GSDMD; LOW QUALITY PROTEIN: gasdermin-D [KO:K20917]
109570535  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
109572614  interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
109556202  JAK1; LOW QUALITY PROTEIN: tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
109561587  TYK2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
109568771  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
109559357  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
109564781  IRF9; interferon regulatory factor 9 isoform X1 [KO:K04693]
109563399  TLR4; toll-like receptor 4 isoform X1 [KO:K10160]
109561728  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
109576356  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
109559201  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
109562082  TMEM173; stimulator of interferon genes protein [KO:K12654]
Compound
C00002  ATP
C00076  Calcium cation
C00155  L-Homocysteine
C00238  Potassium cation
C00533  Nitric oxide
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:23124073
  Authors
Vandenabeele P, Bertrand MJ
  Title
The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling.
  Journal
Nat Rev Immunol 12:833-44 (2012)
DOI:10.1038/nri3325
Reference
PMID:16493424
  Authors
Strober W, Murray PJ, Kitani A, Watanabe T
  Title
Signalling pathways and molecular interactions of NOD1 and NOD2.
  Journal
Nat Rev Immunol 6:9-20 (2006)
DOI:10.1038/nri1747
Reference
PMID:24718315
  Authors
Estornes Y, Bertrand MJ
  Title
IAPs, regulators of innate immunity and inflammation.
  Journal
Semin Cell Dev Biol 39:106-14 (2015)
DOI:10.1016/j.semcdb.2014.03.035
Reference
PMID:24707857
  Authors
Jakopin Z
  Title
Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway.
  Journal
J Med Chem 57:6897-918 (2014)
DOI:10.1021/jm401841p
Reference
PMID:25526305
  Authors
Caruso R, Warner N, Inohara N, Nunez G
  Title
NOD1 and NOD2: signaling, host defense, and inflammatory disease.
  Journal
Immunity 41:898-908 (2014)
DOI:10.1016/j.immuni.2014.12.010
Reference
PMID:19767725
  Authors
Murray PJ
  Title
Beyond peptidoglycan for Nod2.
  Journal
Nat Immunol 10:1053-4 (2009)
DOI:10.1038/ni1009-1053
Reference
PMID:20643110
  Authors
Lecat A, Piette J, Legrand-Poels S
  Title
The protein Nod2: an innate receptor more complex than previously assumed.
  Journal
Biochem Pharmacol 80:2021-31 (2010)
DOI:10.1016/j.bcp.2010.07.016
Reference
PMID:26655628
  Authors
Man SM, Kanneganti TD
  Title
Converging roles of caspases in inflammasome activation, cell death and innate immunity.
  Journal
Nat Rev Immunol 16:7-21 (2016)
DOI:10.1038/nri.2015.7
Reference
PMID:27291964
  Authors
Broz P, Dixit VM
  Title
Inflammasomes: mechanism of assembly, regulation and signalling.
  Journal
Nat Rev Immunol 16:407-20 (2016)
DOI:10.1038/nri.2016.58
Reference
PMID:25879280
  Authors
Man SM, Kanneganti TD
  Title
Regulation of inflammasome activation.
  Journal
Immunol Rev 265:6-21 (2015)
DOI:10.1111/imr.12296
Reference
PMID:26549800
  Authors
Jo EK, Kim JK, Shin DM, Sasakawa C
  Title
Molecular mechanisms regulating NLRP3 inflammasome activation.
  Journal
Cell Mol Immunol 13:148-59 (2016)
DOI:10.1038/cmi.2015.95
Reference
PMID:23846113
  Authors
Broz P, Monack DM
  Title
Newly described pattern recognition receptors team up against intracellular pathogens.
  Journal
Nat Rev Immunol 13:551-65 (2013)
DOI:10.1038/nri3479
Reference
PMID:22430786
  Authors
Rathinam VA, Vanaja SK, Fitzgerald KA
  Title
Regulation of inflammasome signaling.
  Journal
Nat Immunol 13:333-42 (2012)
DOI:10.1038/ni.2237
Reference
PMID:24840700
  Authors
Sutterwala FS, Haasken S, Cassel SL
  Title
Mechanism of NLRP3 inflammasome activation.
  Journal
Ann N Y Acad Sci 1319:82-95 (2014)
DOI:10.1111/nyas.12458
Reference
PMID:23702978
  Authors
Latz E, Xiao TS, Stutz A
  Title
Activation and regulation of the inflammasomes.
  Journal
Nat Rev Immunol 13:397-411 (2013)
DOI:10.1038/nri3452
Reference
PMID:25145756
  Authors
Blander JM
  Title
A long-awaited merger of the pathways mediating host defence and programmed cell death.
  Journal
Nat Rev Immunol 14:601-18 (2014)
DOI:10.1038/nri3720
Reference
PMID:23215645
  Authors
von Moltke J, Ayres JS, Kofoed EM, Chavarria-Smith J, Vance RE
  Title
Recognition of bacteria by inflammasomes.
  Journal
Annu Rev Immunol 31:73-106 (2013)
DOI:10.1146/annurev-immunol-032712-095944
Reference
PMID:25330206
  Authors
Abais JM, Xia M, Zhang Y, Boini KM, Li PL
  Title
Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?
  Journal
Antioxid Redox Signal 22:1111-29 (2015)
DOI:10.1089/ars.2014.5994
Reference
PMID:25879288
  Authors
Storek KM, Monack DM
  Title
Bacterial recognition pathways that lead to inflammasome activation.
  Journal
Immunol Rev 265:112-29 (2015)
DOI:10.1111/imr.12289
Reference
PMID:27012466
  Authors
Hu H, Sun SC
  Title
Ubiquitin signaling in immune responses.
  Journal
Cell Res 26:457-83 (2016)
DOI:10.1038/cr.2016.40
Reference
PMID:26121197
  Authors
Guo H, Callaway JB, Ting JP
  Title
Inflammasomes: mechanism of action, role in disease, and therapeutics.
  Journal
Nat Med 21:677-87 (2015)
DOI:10.1038/nm.3893
Reference
PMID:26482951
  Authors
Man SM, Kanneganti TD
  Title
Gasdermin D: the long-awaited executioner of pyroptosis.
  Journal
Cell Res 25:1183-4 (2015)
DOI:10.1038/cr.2015.124
Reference
PMID:22819539
  Authors
Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA
  Title
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
  Journal
Cell 150:606-19 (2012)
DOI:10.1016/j.cell.2012.07.007
Reference
PMID:21575908
  Authors
Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B
  Title
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.
  Journal
Cell Host Microbe 9:363-75 (2011)
DOI:10.1016/j.chom.2011.04.008
Reference
PMID:29148036
  Authors
Heilig R, Broz P
  Title
Function and mechanism of the pyrin inflammasome.
  Journal
Eur J Immunol 48:230-238 (2018)
DOI:10.1002/eji.201746947
Reference
PMID:25816776
  Authors
Chakrabarti A, Banerjee S, Franchi L, Loo YM, Gale M Jr, Nunez G, Silverman RH
  Title
RNase L activates the NLRP3 inflammasome during viral infections.
  Journal
Cell Host Microbe 17:466-77 (2015)
DOI:10.1016/j.chom.2015.02.010
Related
pathway
biu04010  MAPK signaling pathway
biu04064  NF-kappa B signaling pathway
biu04140  Autophagy - animal
biu04620  Toll-like receptor signaling pathway
KO pathway
ko04621   
LinkDB

DBGET integrated database retrieval system