KEGG ORTHOLOGY: K12798

ORTHOLOGY: K12798

Entry

K12798                      KO

Symbol

NLRP1, CARD7

Name

NACHT, LRR and PYD domains-containing protein 1

Pathway

map04621

NOD-like receptor signaling pathway

Disease

H01372

Vitiligo

H02588

NLRP1-associated autoinflammation with arthritis and dyskeratosis

H02756

Congenital juvenile recurrent respiratory papillomatosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
Membrane trafficking [BR:ko04131]
Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
Pattern recognition receptors [BR:ko04054]
Cytoplasmic pattern recognition receptors
  NOD-like receptors
   K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1

Genes

HSA:	22861(NLRP1)

PTR:	468451(NLRP1)

PPS:	100972433(NLRP1)

GGO:	101152258(NLRP1)

PON:	100441510(NLRP1)

PPYG:

129018153(NLRP1)

NLE:	100607186(NLRP1)

HMH:	116458363(NLRP1)

SSYN:

129469840(NLRP1)

MCC:	721648(NLRP1)

MCF:	102134580(NLRP1)

MTHB:

126939649

MNI:	105474411(NLRP1)

CSAB:

103242241(NLRP1)

CATY:

105583027(NLRP1)

PANU:

101004175(NLRP1)

TGE:	112609524(NLRP1)

MLEU:

105549934(NLRP1)

RRO:	104656203(NLRP1)

RBB:	108514393(NLRP1)

TFN:	117067839(NLRP1)

PTEH:

113225165(NLRP1)

CANG:

105523674(NLRP1)

CJC:	100412129(NLRP1)

SBQ:	101052367(NLRP1)

CIMI:

108281284(NLRP1)

ANAN:

105722809(NLRP1)

CSYR:

103264379(NLRP1)

MMUR:

105866820 105866821 105879236(NLRP1)

LCAT:

123650662(NLRP1)

PCOQ:

105816975 105822844

OGA:	100957721 100960633 100965829

MMU:	195046(Nlrp1a) 637515(Nlrp1b)

MCAL:

110305069 110305614

MPAH:

110331622 110331806(Nlrp1) 110331807 110331808

RNO:	360557(Nlrp1a) 691998(Nlrp1b)

MCOC:

116076846 116076847 116078493

ANU:	117702103 117710281 117710282 117710283 117710285 117710286 117710287 117710976 117711176

ASYL:

127694397 127694892 127694893 127694894

MUN:	110563436 110564057

CGE:	100756113(Nlrp1) 100756703 100756987 103163801

MAUA:

101836789(Nlrp1) 101837048 106020903 106020915 106020916

PROB:

127218976(Nlrp1)

PLEU:

114688012 114688015 114688678 114689232 114706337 114706363

MORG:

121445425 121456306 121456308 121456340

MFOT:

126513953 126513956 126514099 126514134 126514136

AAMP:

119811456 119812878 119813648 119813649 119813650

NGI:

103752250

HGL:

101723875

CCAN:

109684890 109684893

DORD:

105983308 105983310 105983311 105983489

DSP:	122108583 122108603 122108604 122108605

PLOP:

125365628(Nlrp1)

NCAR:

124979948

MMMA:

107159404(Nlrp1)

ITI:	101954285(Nlrp1)

TUP:	102483486(NLRP1)

GVR:	103591066(NLRP1)

CFA:	489449(NLRP1)

CLUD:

112669137(NLRP1)

VVP:	112924984(NLRP1)

VLG:	121500699(NLRP1)

NPO:	129497814(NLRP1)

AML:	100481297(NLRP1)

UMR:	103660432(NLRP1)

UAH:	113271055(NLRP1)

UAR:	123797133(NLRP1)

ELK:

111161052

LLV:

125087375

MPUF:

101679990(NLRP1)

MNP:	132004569(NLRP1)

MLK:	131815970(NLRP1)

NVS:	122906653(NLRP1)

ORO:	101376214(NLRP1)

EJU:	114225297(NLRP1)

ZCA:	113939138(NLRP1)

HHV:	120246880(NLRP1)

BTA:	528166(NLRP1)

BOM:	102277055(NLRP1)

BIU:	109574454(NLRP1)

BBUB:

102402911(NLRP1)

BBIS:

104993983(NLRP1)

CHX:	102169512(NLRP1)

OAS:	101114035(NLRP1)

BTAX:

128064899(NLRP1)

CSUM:

138083609(NLRP1)

ODA:	120866138(NLRP1)

CCAD:

122446776(NLRP1)

MREE:

136149223(NLRP1)

OVR:	110150186(NLRP1)

MBEZ:

129542099(NLRP1)

SSC:	110256098(NLRP1)

CFR:	102510970(NLRP1)

CBAI:

105068720(NLRP1)

CDK:	105104784(NLRP1)

VPC:	102527817(NLRP1)

BACU:

102999016(NLRP1)

PCAD:

102996987(NLRP1)

ECB:	100072788(NLRP1)

EPZ:	103561175(NLRP1)

EAI:	106825654(NLRP1)

MYB:	102250298 106723601

MYD:	102757021(NLRP1)

MMYO:

118671499 118671512 118671526 118672404

MLF:	102424071 102426798 102427062(NLRP1) 102427677 102429272 102430101

MDT:	132218167(NLRP1) 132218168

MYUM:

138993652 138993990

PKL:	118726836 118727048 118727049

EFUS:

103299921 114228125

MNA:	107527983(NLRP1)

DRO:	112308560 112308729(NLRP1)

SHON:

119001085

AJM:

119046605

PDIC:

114515347 114515350 118502340(NLRP1)

PHAS:

123809204 123809275 123809492 123809493 123809494

MMF:	118634877(NLRP1)

PPAM:

129072257(NLRP1) 129072259

HAI:	109394604(NLRP1)

RFQ:	117013630(NLRP1)

MJV:	108390244(NLRP1)

TOD:	119231491 119231492

SARA:

101549711(NLRP1)

SETR:

126027810(NLRP1)

LAV:

100653868

TMU:

101341227

ETF:	101656036(NLRP1)

DNM:	101424986(NLRP1)

MDO:	103095197(NLRP1)

GAS:

123241106

PCW:	110200585(NLRP1)

TVP:	118839220(NLRP1)

PBRV:

138143471 138177712

PCOC:

116241501

MGP:	100547403 104910812

TPAI:

128091864 128091987

LMUT:

125685977 125686132 125686199

CATA:

CCAY:

DCC:

CABI:

MRV:	120395008 120395019 120404081

ASAO:

SUND:

VKO:

PMUA:

PRAF:

ZVI:	118094368 118095528 118095529

HCG:

128331455

XLA:	108703754 108703849 108703939

DRE:	101882558(nlrp1)

SRX:	107730446 107730448 107749103 107749210

SANH:

107692874

SGH:	107568738 107568743 107600098

CCAR:

109081575 109081589 109095774 109108719

CAUA:

113045372

CGIB:

127951572 127951573

PTET:

122347858 122358980(nlrp1)

LROH:

127177397 127181924 127181931

OMC:	131528630 131528640 131532421

MAMB:

125250134 125251176 125251178 125251180 125251181 125251186

CIDE:

127523021

CERY:

137002830 137003145 137003150 137003153 137003383 137003631

MANU:

PDAB:

CHAR:

SPIL:

TBEN:

GACU:

ELY:

SLUC:

LMIX:

ALAT:

119005728(pycard)

MZE:

112432177

ONL:	102080470 102081097 106098696

OAU:	116319476 116325015

LCF:	108899588 108899589

XGL:

120784446

OKI:	109878778 109878988 109896892

OKE:	118392167 127923257

PJA:

PCHN:

HAZT:

Reference

PMID:11270363

Authors

Bertin J, DiStefano PS

Title

The PYRIN domain: a novel motif found in apoptosis and inflammation proteins.

Journal

Cell Death Differ 7:1273-4 (2000)
DOI:10.1038/sj.cdd.4400774

Sequence

[hsa:22861]

LinkDB

DBGET integrated database retrieval system