KEGG   PATHWAY: alat04020
Entry
alat04020                   Pathway                                
Name
Calcium signaling pathway - Acanthopagrus latus (yellowfin seabream)
Description
Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this external source of signal Ca2+ by activating various entry channels with widely different properties. The voltage-operated channels (VOCs) are found in excitable cells and generate the rapid Ca2+ fluxes that control fast cellular processes. There are many other Ca2+-entry channels, such as the receptor-operated channels (ROCs), for example the NMDA (N-methyl-D-aspartate) receptors (NMDARs) that respond to glutamate. There also are second-messenger-operated channels (SMOCs) and store-operated channels (SOCs).
The other principal source of Ca2+ for signalling is the internal stores that are located primarily in the endoplasmic/sarcoplasmic reticulum (ER/SR), in which inositol-1,4,5-trisphosphate receptors (IP3Rs) or ryanodine receptors (RYRs) regulate the release of Ca2+. The principal activator of these channels is Ca2+ itself and this process of Ca2+-induced Ca2+ release is central to the mechanism of Ca2+ signalling. Various second messengers or modulators also control the release of Ca2+. IP3, which is generated by pathways using different isoforms of phospholipase C (PLCbeta, delta, epsilon, gamma and zeta), regulates the IP3Rs. Cyclic ADP-ribose (cADPR) releases Ca2+ via RYRs. Nicotinic acid adenine dinucleotide phosphate (NAADP) may activate a distinct Ca2+ release mechanism on separate acidic Ca2+ stores. Ca2+ release via the NAADP-sensitive mechanism may also feedback onto either RYRs or IP3Rs. cADPR and NAADP are generated by CD38. This enzyme might be sensitive to the cellular metabolism, as ATP and NADH inhibit it.
The influx of Ca2+ from the environment or release from internal stores causes a very rapid and dramatic increase in cytoplasmic calcium concentration, which has been widely exploited for signal transduction. Some proteins, such as troponin C (TnC) involved in muscle contraction, directly bind to and sense Ca2+. However, in other cases Ca2+ is sensed through intermediate calcium sensors such as calmodulin (CALM).
Class
Environmental Information Processing; Signal transduction
Pathway map
alat04020  Calcium signaling pathway
alat04020

Other DBs
GO: 0019722
Organism
Acanthopagrus latus (yellowfin seabream) [GN:alat]
Gene
119004788  slc8a3; sodium/calcium exchanger 3 isoform X1 [KO:K05849]
119023585  slc8a1a; sodium/calcium exchanger 1a isoform X1 [KO:K05849]
119010605  slc8a2b; sodium/calcium exchanger 2b [KO:K05849]
119031521  slc8a4a; solute carrier family 8 member 4a isoform X1 [KO:K05849]
119031903  slc8a2a; sodium/calcium exchanger 2a isoform X1 [KO:K05849]
119033763  slc8a1b; sodium/calcium exchanger 1b isoform X1 [KO:K05849]
119027797  slc8a4b; solute carrier family 8 member 4b isoform X1 [KO:K05849]
119021292  atp2b2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
119021536  plasma membrane calcium-transporting ATPase 1-like isoform X1 [KO:K05850] [EC:7.2.2.10]
119023234  atp2b3b; plasma membrane calcium-transporting ATPase 3b isoform X1 [KO:K05850] [EC:7.2.2.10]
119024018  atp2b1b; plasma membrane calcium-transporting ATPase 1b [KO:K05850] [EC:7.2.2.10]
119032233  atp2b1a; plasma membrane calcium-transporting ATPase 1a isoform X1 [KO:K05850] [EC:7.2.2.10]
119010303  muscarinic acetylcholine receptor M1-like isoform X1 [KO:K04131]
119024172  dopamine D2-like receptor [KO:K04131]
119033203  chrm3a; muscarinic acetylcholine receptor M3 [KO:K04131]
119004379  chrm5a; muscarinic acetylcholine receptor M5a [KO:K04133]
119013080  chrm5b; muscarinic acetylcholine receptor M5b [KO:K04133]
119030587  adora2ab; adenosine A2a receptor b isoform X1 [KO:K04266]
119020174  adora2aa; adenosine A2a receptor a [KO:K04266]
119031439  adora2b; adenosine receptor A2b [KO:K04267]
119010163  adrb1; beta-1 adrenergic receptor [KO:K04141]
119007839  adrb2a; adrenoceptor beta 2, surface a [KO:K04142]
119031716  beta-2 adrenergic receptor-like [KO:K04142]
119019713  adrb3a; adrenoceptor beta 3a [KO:K04143]
119006937  drd1a; D(1) dopamine receptor [KO:K04144]
119031974  drd1b; dopamine receptor D1b [KO:K04144]
119013105  D(1) dopamine receptor-like [KO:K04144]
119021314  drd5a; D(1B) dopamine receptor [KO:K05840]
119010341  D(5)-like dopamine receptor [KO:K05840]
119034127  D(1)-like dopamine receptor [KO:K05840]
119007158  hrh2a; histamine receptor H2a [KO:K04150]
119030753  hrh2b; histamine receptor H2b [KO:K04150]
119008125  5-hydroxytryptamine receptor 4-like [KO:K04160]
119007386  htr4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
119028483  5-hydroxytryptamine receptor 4 [KO:K04160]
119030503  si:dkey-247m21.3; 5-hydroxytryptamine receptor 4 [KO:K04160]
119008288  htr5ab; 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b [KO:K04161]
119023391  htr6; 5-hydroxytryptamine receptor 6 [KO:K04162]
119018933  htr7c; 5-hydroxytryptamine receptor 7 [KO:K04163]
119033689  5-hydroxytryptamine receptor 7 [KO:K04163]
119022184  gnas; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632]
119021085  guanine nucleotide-binding protein G(s) subunit alpha-like isoform X1 [KO:K04632]
119008535  guanine nucleotide-binding protein G(olf) subunit alpha-like isoform X1 [KO:K04633]
119011050  guanine nucleotide-binding protein G(olf) subunit alpha isoform X1 [KO:K04633]
119027991  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
119011864  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
119006711  adcy2a; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
119017049  adcy2b; adenylate cyclase type 2b isoform X1 [KO:K08042] [EC:4.6.1.1]
119006468  adcy3a; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
119012484  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
119018820  adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
119015111  si:ch211-132f19.7; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
119010641  adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
119012449  si:dkey-206f10.1; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
119007440  adcy9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
119014314  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
119014564  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1 [KO:K04345] [EC:2.7.11.11]
119028389  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
119018496  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
119011561  cAMP-dependent protein kinase catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
119013515  sarcolipin [KO:K22642]
119029582  atp2a2b; sarcoplasmic/endoplasmic reticulum calcium ATPase 2b isoform X1 [KO:K05853] [EC:7.2.2.10]
119009903  atp2a1l; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like isoform X1 [KO:K05853] [EC:7.2.2.10]
119024423  si:dkey-28b4.8; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
119031147  atp2a3; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
119019595  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like isoform X1 [KO:K05853] [EC:7.2.2.10]
119014203  atp2a1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
119031133  stromal interaction molecule 1-like isoform X1 [KO:K16059]
119010770  stim1a; stromal interaction molecule 1a isoform X1 [KO:K16059]
119025670  stim2a; stromal interaction molecule 2 isoform X1 [KO:K18196]
119027315  stim2b; stromal interaction molecule 2 isoform X1 [KO:K18196]
119029529  orai1b; calcium release-activated calcium channel protein 1 [KO:K16056]
119019455  calcium release-activated calcium channel protein 1-like [KO:K16056]
119031519  orai2; protein orai-2 isoform X1 [KO:K16057]
119032303  cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
119023270  cacna1db; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
119021040  cacna1da; calcium channel, voltage-dependent, L type, alpha 1D subunit, a isoform X1 [KO:K04851]
119022437  cacna1fa; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04853]
119023017  cacna1fb; calcium channel, voltage-dependent, L type, alpha 1F subunit isoform X1 [KO:K04853]
119023476  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
119020797  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like isoform X1 [KO:K04857]
119016818  cacna1ab; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b isoform X1 [KO:K04344]
119013820  cacna1aa; voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X1 [KO:K04344]
119029777  cacna1bb; voltage-dependent N-type calcium channel subunit alpha-1B isoform X1 [KO:K04849]
119019048  cacna1ba; calcium channel, voltage-dependent, N type, alpha 1B subunit, a isoform X1 [KO:K04849]
119028470  voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
119011146  cacna1eb; voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
119009685  cacna1g; voltage-dependent T-type calcium channel subunit alpha-1G isoform X1 [KO:K04854]
119014173  cacna1ha; voltage-dependent T-type calcium channel subunit alpha-1H [KO:K04855]
119014463  cacna1ia; voltage-dependent T-type calcium channel subunit alpha-1I isoform X1 [KO:K04856]
119024399  voltage-dependent T-type calcium channel subunit alpha-1I-like isoform X1 [KO:K04856]
119007925  neuronal acetylcholine receptor subunit alpha-7-like [KO:K04809]
119005738  neuronal acetylcholine receptor subunit alpha-7-like isoform X1 [KO:K04809]
119028579  neuronal acetylcholine receptor subunit alpha-7-like [KO:K04809]
119016630  chrna11; cholinergic receptor, nicotinic, alpha 11 [KO:K04809]
119025121  neuronal acetylcholine receptor subunit alpha-7 isoform X1 [KO:K04809]
119018796  neuronal acetylcholine receptor subunit alpha-7-like isoform X1 [KO:K04809]
119029913  grin1a; glutamate receptor ionotropic, NMDA 1a isoform X1 [KO:K05208]
119019741  grin1b; glutamate receptor ionotropic, NMDA 1b isoform X1 [KO:K05208]
119014584  grin2aa; glutamate receptor ionotropic, NMDA 2A isoform X1 [KO:K05209]
119020183  grin2bb; glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b isoform X1 [KO:K05210]
119013946  glutamate receptor ionotropic, NMDA 2B isoform X1 [KO:K05210]
119014605  grin2ca; glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca [KO:K05211]
119010326  glutamate receptor ionotropic, NMDA 2C-like isoform X1 [KO:K05211]
119005709  glutamate receptor ionotropic, NMDA 2D [KO:K05212]
119017376  grin2da; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
119029476  grin3a; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
119028858  grin3bb; glutamate receptor ionotropic, NMDA 3B isoform X1 [KO:K05214]
119034285  grin3ba; glutamate receptor ionotropic, NMDA 3B isoform X1 [KO:K05214]
119030733  p2rx1; P2X purinoceptor 1 isoform X1 [KO:K05215]
119020129  p2rx2; P2X purinoceptor 2 [KO:K05216]
119007192  p2rx3a; P2X purinoceptor 3a [KO:K05217]
119010871  p2rx3b; P2X purinoceptor 3b [KO:K05217]
119019083  p2rx4b; P2X purinoceptor 4b [KO:K05218]
119030683  P2X purinoceptor 5-like isoform X1 [KO:K05219]
119031694  p2rx5; P2X purinoceptor 5 [KO:K05219]
119019914  p2rx7; P2X purinoceptor 7 isoform X1 [KO:K05220]
119030801  ryanodine receptor 1-like [KO:K04961]
119034262  ryr1b; ryanodine receptor 1b isoform X1 [KO:K04961]
119009617  ryr2a; ryanodine receptor 2 isoform X1 [KO:K04962]
119033213  ryr2b; ryanodine receptor 2 isoform X1 [KO:K04962]
119005103  ryanodine receptor 3-like isoform X1 [KO:K04963]
119013079  ryanodine receptor 3-like isoform X1 [KO:K04963]
119013018  probable serine/threonine-protein kinase kinX [KO:K23449]
119011256  casq1a; calsequestrin-1a [KO:K23468]
119027184  casq1b; calsequestrin-1b isoform X1 [KO:K23468]
119015433  calsequestrin-2-like [KO:K23445]
119025831  casq2; calsequestrin-2 [KO:K23445]
119009064  unm_hu7910; aspartyl/asparaginyl beta-hydroxylase isoform X1 [KO:K00476] [EC:1.14.11.16]
119009090  uncharacterized abhydrolase domain-containing protein DDB_G0269086-like [KO:K00476] [EC:1.14.11.16]
119010859  asph; aspartyl/asparaginyl beta-hydroxylase isoform X1 [KO:K00476] [EC:1.14.11.16]
119006956  cysltr1; cysteinyl leukotriene receptor 1 [KO:K04322]
119026718  cysteinyl leukotriene receptor 2-like isoform X1 [KO:K04322]
119025071  muscarinic acetylcholine receptor M2-like [KO:K04130]
119032827  chrm2a; muscarinic acetylcholine receptor M2a [KO:K04130]
119029466  adra1ab; alpha-1A adrenergic receptor isoform X1 [KO:K04135]
119019620  adra1aa; adrenoceptor alpha 1Aa [KO:K04135]
119008124  alpha-1A adrenergic receptor-like [KO:K04136]
119030785  alpha-1A adrenergic receptor-like [KO:K04136]
119019940  adra1d; alpha-1A adrenergic receptor [KO:K04137]
119008627  agtr1b; type-1 angiotensin II receptor [KO:K04166]
119025911  ednraa; endothelin receptor type Aa [KO:K04197]
119026850  endothelin receptor type B-like isoform X1 [KO:K04197]
119007920  endothelin receptor type B-like [KO:K04198]
119011927  ednrba; endothelin receptor Ba [KO:K04198]
119025886  ednrbb; endothelin receptor type B [KO:K04198]
119029847  proteinase-activated receptor 1-like [KO:K03914]
119030072  proteinase-activated receptor 1-like [KO:K03914]
119030440  proteinase-activated receptor 1-like [KO:K03914]
119019363  f2r; proteinase-activated receptor 1 [KO:K03914]
119012531  grm1a; metabotropic glutamate receptor 1 isoform X1 [KO:K04603]
119034234  grm1b; metabotropic glutamate receptor 1b isoform X1 [KO:K04603]
119006147  grm5b; metabotropic glutamate receptor 5b [KO:K04604]
119031317  grm5a; glutamate receptor, metabotropic 5a [KO:K04604]
119018231  grpr; gastrin-releasing peptide receptor [KO:K04169]
119026468  gastrin-releasing peptide receptor-like [KO:K04169]
119021269  hrh1; histamine H1 receptor [KO:K04149]
119028627  htr2b; 5-hydroxytryptamine receptor 2B isoform X1 [KO:K04157]
119025914  htr2aa; 5-hydroxytryptamine receptor 2A isoform X1 [KO:K04157]
119027827  htr2cl1; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 [KO:K04157]
119033339  lutropin-choriogonadotropic hormone receptor-like isoform X1 [KO:K04248]
119034122  lhcgr; lutropin-choriogonadotropic hormone receptor [KO:K04248]
119023491  ntsr1; neurotensin receptor type 1 isoform X1 [KO:K04211]
119021955  oxtr; oxytocin receptor [KO:K04229]
119021971  oxtrl; LOW QUALITY PROTEIN: oxytocin receptor like [KO:K04229]
119025069  avpr1aa; arginine vasopressin receptor 1Aa [KO:K04226]
119032366  arg8-vasotocin receptor-like [KO:K04226]
119010842  ltb4r2b; leukotriene B4 receptor 2b [KO:K04297]
119034309  platelet-activating factor receptor-like [KO:K04279]
119034310  platelet-activating factor receptor-like [KO:K04279]
119034311  platelet-activating factor receptor-like [KO:K04279]
119034312  platelet-activating factor receptor-like [KO:K04279]
119013688  prostaglandin E2 receptor EP1 subtype-like [KO:K04258]
119033864  prostaglandin E2 receptor EP1 subtype-like [KO:K04258]
119013991  ptger1c; prostaglandin E receptor 1c (subtype EP1) [KO:K04258]
119028928  ptger3; prostaglandin E2 receptor EP3 subtype [KO:K04260]
119028878  ptgfr; prostaglandin F2-alpha receptor [KO:K04262]
119004766  bdkrb1; B1 bradykinin receptor isoform X1 [KO:K03916]
119004768  B2 bradykinin receptor-like isoform X1 [KO:K03916]
119004769  B2 bradykinin receptor-like [KO:K03916]
119004920  B2 bradykinin receptor-like [KO:K03916]
119034278  B2 bradykinin receptor-like [KO:K03916]
119030063  substance-P receptor-like [KO:K04222]
119018924  tacr1a; tachykinin receptor 1a isoform X1 [KO:K04222]
119018801  tacr2; substance-K receptor [KO:K04223]
119028872  tacr3a; tachykinin receptor 3a isoform X1 [KO:K04224]
119013306  tacr3l; tachykinin receptor 3-like [KO:K04224]
119029232  tbxa2r; thromboxane A2 receptor isoform X1 [KO:K04264]
119006090  trhra; thyrotropin-releasing hormone receptor [KO:K04282]
119014945  trhrb; thyrotropin-releasing hormone receptor b [KO:K04282]
119022115  thyrotropin-releasing hormone receptor [KO:K04282]
119023896  trhr2; thyrotropin releasing hormone receptor 2 isoform X1 [KO:K04282]
119015167  cckbra; cholecystokinin receptor [KO:K04194]
119025793  cholecystokinin receptor [KO:K04194]
119026975  cckar; cholecystokinin receptor type A isoform X1 [KO:K04194]
119011440  C-X-C chemokine receptor type 4-like [KO:K04189]
119026431  cxcr4b; C-X-C chemokine receptor type 4b [KO:K04189]
119030309  guanine nucleotide-binding protein G(q) subunit alpha-like isoform X1 [KO:K04634]
119019628  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
119028320  guanine nucleotide-binding protein G(q) subunit alpha isoform X1 [KO:K04635]
119034345  gna11b; guanine nucleotide-binding protein subunit alpha-11b isoform X1 [KO:K04635]
119019063  gna14a; guanine nucleotide-binding protein subunit alpha-14 isoform X1 [KO:K04636]
119028443  guanine nucleotide-binding protein subunit alpha-11-like [KO:K04637]
119008156  egf; pro-epidermal growth factor [KO:K04357]
119021253  tgfa; protransforming growth factor alpha isoform X1 [KO:K08774]
119021530  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
119014493  platelet-derived growth factor subunit A-like [KO:K04359]
119028330  si:ch211-79m20.1; transcription factor SPT20 homolog isoform X1 [KO:K17386]
119007900  pdgfc; platelet-derived growth factor C isoform X1 [KO:K05450]
119012997  pdgfd; platelet-derived growth factor D [KO:K05450]
119007710  fgf1a; putative fibroblast growth factor 1 isoform X1 [KO:K18496]
119031782  putative fibroblast growth factor 1 isoform X1 [KO:K18496]
119007245  fgf2; fibroblast growth factor 2 [KO:K18497]
119006923  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
119006924  fgf24; fibroblast growth factor 24 [KO:K04358]
119006939  fgf16; fibroblast growth factor 16 [KO:K04358]
119007627  fibroblast growth factor 4-like [KO:K04358]
119007650  fgf20b; fibroblast growth factor 20b [KO:K04358]
119028723  fgf8b; fibroblast growth factor 8b [KO:K04358]
119028735  fgf22; fibroblast growth factor 22 [KO:K04358]
119023280  fibroblast growth factor 20-like [KO:K04358]
119029968  fgf10a; fibroblast growth factor 10a [KO:K04358]
119024007  fibroblast growth factor 6-like [KO:K04358]
119017966  fgf7; fibroblast growth factor 7 [KO:K04358]
119018286  fgf3; fibroblast growth factor 3 [KO:K04358]
119018300  fgf4; fibroblast growth factor 4 [KO:K04358]
119025486  fgf9; fibroblast growth factor 4A isoform X1 [KO:K04358]
119018948  fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
119032426  fibroblast growth factor 4B-like [KO:K04358]
119033070  fgf8a; fibroblast growth factor 8 isoform X1 [KO:K04358]
119020053  fgf10b; fibroblast growth factor 10b [KO:K04358]
119020234  fgf5; fibroblast growth factor 5 [KO:K04358]
119017935  fgf19; fibroblast growth factor 19 [KO:K22603]
119010094  fgf21; fibroblast growth factor 21 isoform X1 [KO:K22429]
119024006  fibroblast growth factor 23-like [KO:K22428]
119032425  fgf23; fibroblast growth factor 23 [KO:K22428]
119006668  vegfaa; vascular endothelial growth factor A-A isoform X1 [KO:K05448]
119007531  vegfba; vascular endothelial growth factor A [KO:K05448]
119012338  vegfab; vascular endothelial growth factor Ab isoform X1 [KO:K05448]
119028898  vegfc; vascular endothelial growth factor C isoform X1 [KO:K05449]
119015500  vascular endothelial growth factor C-like [KO:K05449]
119018561  vegfd; vascular endothelial growth factor D [KO:K05449]
119021504  ngfb; nerve growth factor [KO:K02582]
119023601  ngfa; neurotrophin-7 [KO:K02582]
119025110  hepatocyte growth factor isoform X1 [KO:K05460]
119032739  hgfa; hepatocyte growth factor a isoform X1 [KO:K05460]
119021700  mst1; hepatocyte growth factor-like protein [KO:K23441]
119029420  gdnfa; glial cell line-derived neurotrophic factor isoform X1 [KO:K05452]
119019631  glial cell line-derived neurotrophic factor-like [KO:K05452]
119008592  melanoma receptor tyrosine-protein kinase-like [KO:K04361] [EC:2.7.10.1]
119010740  egfra; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
119009342  erbb2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
119021386  erbb3a; receptor tyrosine-protein kinase erbB-3a [KO:K05084] [EC:2.7.10.1]
119023591  erbb3b; receptor tyrosine-protein kinase erbB-3b [KO:K05084] [EC:2.7.10.1]
119015032  receptor tyrosine-protein kinase erbB-4-like isoform X1 [KO:K05085] [EC:2.7.10.1]
119025841  receptor tyrosine-protein kinase erbB-4-like [KO:K05085] [EC:2.7.10.1]
119028306  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
119008149  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
119031152  platelet-derived growth factor receptor beta-like isoform X1 [KO:K05089] [EC:2.7.10.1]
119030510  fgfr1b; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1b [KO:K04362] [EC:2.7.10.1]
119019249  fgfr1a; fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
119030700  si:ch211-167j9.5; tyrosine kinase receptor Cad96Ca [KO:K05093] [EC:2.7.10.1]
119033721  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
119004435  fgfr3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
119031455  fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
119008427  flt1; vascular endothelial growth factor receptor 1 isoform X1 [KO:K05096] [EC:2.7.10.1]
119007165  kdrl; vascular endothelial growth factor receptor kdr-like [KO:K05096] [EC:2.7.10.1]
119007392  flt4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
119029058  kdr; vascular endothelial growth factor receptor 2 isoform X1 [KO:K05098] [EC:2.7.10.1]
119005315  ntrk1; high affinity nerve growth factor receptor [KO:K03176] [EC:2.7.10.1]
119030549  ntrk2b; neurotrophic tyrosine kinase, receptor, type 2b isoform X1 [KO:K04360] [EC:2.7.10.1]
119019740  ntrk2a; neurotrophic tyrosine kinase, receptor, type 2a isoform X1 [KO:K04360] [EC:2.7.10.1]
119024832  NT-3 growth factor receptor-like isoform X1 [KO:K05101] [EC:2.7.10.1]
119018748  ntrk3b; NT-3 growth factor receptor isoform X1 [KO:K05101] [EC:2.7.10.1]
119024820  met; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
119020603  mst1rb; macrophage-stimulating protein receptor [KO:K05100] [EC:2.7.10.1]
119020986  macrophage-stimulating protein receptor-like [KO:K05100] [EC:2.7.10.1]
119033746  ret; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
119004446  T cell receptor beta chain MC.7.G5-like [KO:K10785]
119013783  Ig heavy chain Mem5-like [KO:K06856]
119013995  immunoglobulin gamma-1 heavy chain-like [KO:K06856]
119013998  Ig heavy chain V region 3 [KO:K06856]
119008476  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
119014598  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A isoform X1 [KO:K05857] [EC:3.1.4.11]
119015094  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
119010195  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like [KO:K05857] [EC:3.1.4.11]
119010901  plcd1b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1b isoform X1 [KO:K05857] [EC:3.1.4.11]
119026139  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
119004923  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
119012330  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like [KO:K05858] [EC:3.1.4.11]
119026637  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
119013046  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
119034103  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
119029127  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
119022912  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
119024782  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
119009624  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
119024467  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
119020522  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
119021190  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
119024134  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
119022453  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
119008766  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like [KO:K01242] [EC:3.2.2.6 2.4.99.20]
119008641  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like isoform X1 [KO:K01242] [EC:3.2.2.6 2.4.99.20]
119008934  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like isoform X1 [KO:K01242] [EC:3.2.2.6 2.4.99.20]
119009095  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like [KO:K01242] [EC:3.2.2.6 2.4.99.20]
119013827  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like [KO:K01242] [EC:3.2.2.6 2.4.99.20]
119019253  tpcn1; two pore calcium channel protein 1 isoform X1 [KO:K16896]
119018762  tpcn2; two pore calcium channel protein 2 isoform X1 [KO:K14077]
119018765  uncharacterized protein LOC119018765 isoform X1 [KO:K14077]
119026663  mcoln1a; mucolipin-1a [KO:K04992]
119013657  mcoln1b; mucolipin-1b [KO:K04992]
119028165  mcoln2; mucolipin-2 isoform X1 [KO:K04993]
119028199  mcoln3b; mucolipin-3 isoform X1 [KO:K04994]
119011658  mcoln3a; mucolipin-3 [KO:K04994]
119005970  sphk2; sphingosine kinase 2 [KO:K04718] [EC:2.7.1.91]
119026682  sphingosine kinase 1-like isoform X1 [KO:K04718] [EC:2.7.1.91]
119013253  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
119033611  mcu; calcium uniporter protein, mitochondrial [KO:K20858]
119031553  vdac1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
119009719  voltage-dependent anion-selective channel protein 2-like [KO:K15040]
119033916  vdac2; voltage-dependent anion-selective channel protein 2 [KO:K15040]
119029867  zgc:56235; voltage-dependent anion-selective channel protein 2 isoform X1 [KO:K15041]
119019040  vdac3; voltage-dependent anion-selective channel protein 3 isoform X1 [KO:K15041]
119007288  slc25a5; ADP/ATP translocase 2 [KO:K05863]
119023274  slc25a4; ADP/ATP translocase 1 [KO:K05863]
119031444  si:dkey-251i10.1; ADP/ATP translocase 2 [KO:K05863]
119010264  peptidyl-prolyl cis-trans isomerase A-like [KO:K09565] [EC:5.2.1.8]
119033557  ppifa; peptidylprolyl isomerase Fa isoform X1 [KO:K09565] [EC:5.2.1.8]
119022144  tnnc1b; troponin C type 1b (slow) [KO:K05865]
119023339  tnnc1a; troponin C type 1a (slow) [KO:K05865]
119022157  troponin C, skeletal muscle-like isoform X1 [KO:K12042]
119022158  troponin C, skeletal muscle [KO:K12042]
119007396  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
119005021  calm1a; calmodulin-1a [KO:K02183]
119017931  calmodulin-like protein 4 [KO:K02183]
119024515  calml4b; calmodulin-like protein 4 isoform X1 [KO:K02183]
119012445  calm1b; calmodulin-1b [KO:K02183]
119033670  calm2a; calmodulin 2a (phosphorylase kinase, delta) isoform X1 [KO:K02183]
119020694  calglandulin-like isoform X1 [KO:K02183]
119009517  phkg2; phosphorylase b kinase gamma catalytic chain, liver/testis isoform [KO:K00871] [EC:2.7.11.19]
119030366  phkg1a; phosphorylase kinase, gamma 1a (muscle) [KO:K00871] [EC:2.7.11.19]
119017658  phkb; phosphorylase b kinase regulatory subunit beta isoform X1 [KO:K07190]
119018506  phka2; phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1 [KO:K07190]
119027359  phka1a; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1 [KO:K07190]
119009847  myosin light chain kinase, smooth muscle-like isoform X1 [KO:K00907] [EC:2.7.11.18]
119029312  mylk4b; myosin light chain kinase 2, skeletal/cardiac muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
119010884  mylk4a; myosin light chain kinase 2, skeletal/cardiac muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
119025568  mylka; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
119014215  mylk5; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
119021751  camk1ga; calcium/calmodulin-dependent protein kinase IGa [KO:K08794] [EC:2.7.11.17]
119022339  camk1gb; calcium/calmodulin-dependent protein kinase IGb isoform X1 [KO:K08794] [EC:2.7.11.17]
119032696  camk1da; calcium/calmodulin-dependent protein kinase type 1D isoform X1 [KO:K08794] [EC:2.7.11.17]
119020371  camk1b; calcium/calmodulin-dependent protein kinase type 1 isoform X1 [KO:K08794] [EC:2.7.11.17]
119020959  camk1a; calcium/calmodulin-dependent protein kinase type 1 [KO:K08794] [EC:2.7.11.17]
119022218  camk2d2; calcium/calmodulin-dependent protein kinase type II delta 2 chain isoform X1 [KO:K04515] [EC:2.7.11.17]
119009403  calcium/calmodulin-dependent protein kinase type II subunit gamma-like isoform X1 [KO:K04515] [EC:2.7.11.17]
119030185  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
119031491  camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
119018931  camk2b1; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 isoform X1 [KO:K04515] [EC:2.7.11.17]
119026632  calcium/calmodulin-dependent protein kinase type II delta chain-like isoform X1 [KO:K04515] [EC:2.7.11.17]
119033328  camk2g2; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
119027066  calcium/calmodulin-dependent protein kinase type II delta 1 chain isoform X1 [KO:K04515] [EC:2.7.11.17]
119028565  si:ch73-60h1.1; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
119006992  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119029699  ppp3ccb; protein phosphatase 3, catalytic subunit, gamma isozyme, b isoform X1 [KO:K04348] [EC:3.1.3.16]
119030903  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119018987  ppp3cca; protein phosphatase 3, catalytic subunit, gamma isozyme, a isoform X1 [KO:K04348] [EC:3.1.3.16]
119027321  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119024175  ppp3r1b; calcineurin subunit B type 1b [KO:K06268]
119033000  calcineurin subunit B type 1 isoform X1 [KO:K06268]
119021092  tfeb; transcription factor EB isoform X1 [KO:K15590]
119005327  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
119017371  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
119023362  nfatc2a; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
119020662  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
119025118  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
119018730  nfatc3a; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
119011686  nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1 [KO:K17334]
119019240  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
119009027  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like [KO:K13755] [EC:3.1.4.17]
119010808  pde1cb; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
119025443  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
119021161  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like isoform X1 [KO:K13755] [EC:3.1.4.17]
119015368  protein-tyrosine kinase 2-beta-like [KO:K05871] [EC:2.7.10.2]
119012956  ptk2bb; protein tyrosine kinase 2 beta, b isoform X1 [KO:K05871] [EC:2.7.10.2]
119008098  si:ch73-22a13.3; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
119004506  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
119031404  itpkca; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
119012222  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
119033018  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
119014663  si:ch73-374l24.1; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
119019491  prkcaa; protein kinase C, alpha, a isoform X1 [KO:K02677] [EC:2.7.11.13]
119017686  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
119014168  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
119006482  prkcg; protein kinase C alpha type isoform X1 [KO:K19663] [EC:2.7.11.13]
Compound
C00002  ATP
C00004  NADH
C00076  Calcium cation
C00165  Diacylglycerol
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01330  Sodium cation
C06124  Sphingosine 1-phosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C13050  Cyclic ADP-ribose
C13051  Nicotinic acid adenine dinucleotide phosphate
Reference
PMID:12838335
  Authors
Berridge MJ, Bootman MD, Roderick HL.
  Title
Calcium signalling: dynamics, homeostasis and remodelling.
  Journal
Nat Rev Mol Cell Biol 4:517-29 (2003)
DOI:10.1038/nrm1155
Reference
PMID:11413485
  Authors
Berridge MJ, Lipp P, Bootman MD.
  Title
The versatility and universality of calcium signalling.
  Journal
Nat Rev Mol Cell Biol 1:11-21 (2000)
DOI:10.1038/35036035
Reference
PMID:15111104
  Authors
Wang MC, Dolphin A, Kitmitto A.
  Title
L-type voltage-gated calcium channels: understanding function through structure.
  Journal
FEBS Lett 564:245-50 (2004)
DOI:10.1016/S0014-5793(04)00253-4
Reference
PMID:11299192
  Authors
Ferrier GR, Howlett SE.
  Title
Cardiac excitation-contraction coupling: role of membrane potential in regulation of contraction.
  Journal
Am J Physiol Heart Circ Physiol 280:H1928-44 (2001)
DOI:10.1152/ajpheart.2001.280.5.H1928
Reference
PMID:11698232
  Authors
Keef KD, Hume JR, Zhong J.
  Title
Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases.
  Journal
Am J Physiol Cell Physiol 281:C1743-56 (2001)
DOI:10.1152/ajpcell.2001.281.6.C1743
Reference
PMID:8125957
  Authors
Hell JW, Appleyard SM, Yokoyama CT, Warner C, Catterall WA.
  Title
Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini.
  Journal
J Biol Chem 269:7390-6 (1994)
Reference
PMID:15000521
  Authors
Yunker AM.
  Title
Modulation and pharmacology of low voltage-activated ("T-Type") calcium channels.
  Journal
J Bioenerg Biomembr 35:577-98 (2003)
DOI:10.1023/B:JOBB.0000008025.65675.37
Reference
PMID:9149541
  Authors
Yakel JL.
  Title
Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription.
  Journal
Trends Pharmacol Sci 18:124-34 (1997)
DOI:10.1016/S0165-6147(97)01046-8
Reference
PMID:10997573
  Authors
Fukunaga K, Miyamoto E.
  Title
A working model of CaM kinase II activity in hippocampal long-term potentiation and memory.
  Journal
Neurosci Res 38:3-17 (2000)
DOI:10.1016/S0168-0102(00)00139-5
Reference
PMID:9235901
  Authors
Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ.
  Title
Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.
  Journal
J Biol Chem 272:19125-32 (1997)
DOI:10.1074/jbc.272.31.19125
Reference
PMID:7861177
  Authors
Furuichi T, Mikoshiba K.
  Title
Inositol 1, 4, 5-trisphosphate receptor-mediated Ca2+ signaling in the brain.
  Journal
J Neurochem 64:953-60 (1995)
DOI:10.1046/j.1471-4159.1995.64030953.x
Reference
PMID:14572802
  Authors
Bruce JI, Straub SV, Yule DI.
  Title
Crosstalk between cAMP and Ca2+ signaling in non-excitable cells.
  Journal
Cell Calcium 34:431-44 (2003)
DOI:10.1016/S0143-4160(03)00150-7
Reference
PMID:10331643
  Authors
Lee HC, Munshi C, Graeff R.
  Title
Structures and activities of cyclic ADP-ribose, NAADP and their metabolic enzymes.
  Journal
Mol Cell Biochem 193:89-98 (1999)
DOI:10.1007/978-1-4419-8740-2_13
Reference
PMID:11080247
  Authors
Crompton M.
  Title
Mitochondrial intermembrane junctional complexes and their role in cell death.
  Journal
J Physiol 529 Pt 1:11-21 (2000)
DOI:10.1111/j.1469-7793.2000.00011.x
Reference
PMID:10508738
  Authors
Grewal SS, York RD, Stork PJ.
  Title
Extracellular-signal-regulated kinase signalling in neurons.
  Journal
Curr Opin Neurobiol 9:544-53 (1999)
DOI:10.1016/S0959-4388(99)00010-0
Reference
PMID:12972622
  Authors
Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV.
  Title
Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.
  Journal
Mol Cell Biol 23:7068-81 (2003)
DOI:10.1128/MCB.23.19.7068-7081.2003
Reference
PMID:14517314
  Authors
Hutchins JR, Dikovskaya D, Clarke PR.
  Title
Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.
  Journal
Mol Biol Cell 14:4003-14 (2003)
DOI:10.1091/mbc.E03-02-0061
Reference
PMID:21338471
  Authors
Tornquist K
  Title
Sphingosine 1-phosphate, sphingosine kinase and autocrine calcium signalling in thyroid cells.
  Journal
Acta Physiol (Oxf) 204:151-7 (2012)
DOI:10.1111/j.1748-1716.2011.02265.x
Reference
PMID:22129055
  Authors
Feske S
  Title
Immunodeficiency due to defects in store-operated calcium entry.
  Journal
Ann N Y Acad Sci 1238:74-90 (2011)
DOI:10.1111/j.1749-6632.2011.06240.x
Reference
PMID:22002090
  Authors
Giachini FR, Lima VV, Hannan JL, Carneiro FS, Webb RC, Tostes RC
  Title
STIM1/Orai1-mediated store-operated Ca2+ entry: the tip of the iceberg.
  Journal
Braz J Med Biol Res 44:1080-7 (2011)
DOI:10.1590/S0100-879X2011007500133
Reference
PMID:19172794
  Authors
Baba Y, Kurosaki T
  Title
[Regulation of store-operated calcium entry by STIM1].
  Journal
Seikagaku 80:1123-8 (2008)
Reference
PMID:19475418
  Authors
Galione A, Evans AM, Ma J, Parrington J, Arredouani A, Cheng X, Zhu MX
  Title
The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.
  Journal
Pflugers Arch 458:869-76 (2009)
DOI:10.1007/s00424-009-0682-y
Reference
PMID:19434403
  Authors
Beard NA, Wei L, Dulhunty AF
  Title
Ca(2+) signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin.
  Journal
Eur Biophys J 39:27-36 (2009)
DOI:10.1007/s00249-009-0449-6
Reference
PMID:26228554
  Authors
Marty I
  Title
Triadin regulation of the ryanodine receptor complex.
  Journal
J Physiol 593:3261-6 (2015)
DOI:10.1113/jphysiol.2014.281147
Reference
PMID:20807542
  Authors
Arvanitis DA, Vafiadaki E, Sanoudou D, Kranias EG
  Title
Histidine-rich calcium binding protein: the new regulator of sarcoplasmic reticulum calcium cycling.
  Journal
J Mol Cell Cardiol 50:43-9 (2011)
DOI:10.1016/j.yjmcc.2010.08.021
Related
pathway
alat04010  MAPK signaling pathway
alat04070  Phosphatidylinositol signaling system
alat04210  Apoptosis
KO pathway
ko04020   
LinkDB

DBGET integrated database retrieval system