| |
KO |
 09100 Metabolism
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09120 Genetic Information Processing
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|
 09130 Environmental Information Processing
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|
|
09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:pmur04010]
|
04013 MAPK signaling pathway - fly
|
04016 MAPK signaling pathway - plant
|
04011 MAPK signaling pathway - yeast
|
04012 ErbB signaling pathway [PATH:pmur04012]
|
107290128 EGF; pro-epidermal growth factor
107283236 TGFA; protransforming growth factor alpha
107302391 AREG; amphiregulin
107284695 EGFR; epidermal growth factor receptor isoform X2
107303070 ERBB2; receptor tyrosine-protein kinase erbB-2
107298984 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like
107287257 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
107292601 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
107293182 calcium/calmodulin-dependent protein kinase type II subunit gamma
107286231 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
107290559 calcium/calmodulin-dependent protein kinase type II subunit alpha
107286689 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta
107285104 PRKCB; protein kinase C beta type
107282442 protein kinase C gamma type
107288141 protein kinase C gamma type-like
107285391 CBL; E3 ubiquitin-protein ligase CBL
107287381 CBLB; E3 ubiquitin-protein ligase CBL-B
107282650 signal transducer and activator of transcription 5B
107298083 signal transducer and activator of transcription 5B-like
107297709 signal transducer and activator of transcription 5B
107287254 SRC; proto-oncogene tyrosine-protein kinase Src
107295151 CRKL; crk-like protein
107298840 crk-like protein
107289561 CRK; adapter molecule crk isoform X1
107282724 crk-like protein
107291344 ABL1; tyrosine-protein kinase ABL1
107283361 ABL2; tyrosine-protein kinase ABL2
107288838 NCK2; cytoplasmic protein NCK2
107294968 PAK2; serine/threonine-protein kinase PAK 2
107295917 serine/threonine-protein kinase PAK 3
107291657 PAK4; serine/threonine-protein kinase PAK 4
107285367 PAK5; serine/threonine-protein kinase PAK 5
107290814 serine/threonine-protein kinase PAK 6
107282461 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4
107291150 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7
107294632 MAPK9; mitogen-activated protein kinase 9
107293954 MAPK8; mitogen-activated protein kinase 8 isoform X3
107303183 MAPK10; mitogen-activated protein kinase 10 isoform X1
107302456 JUN; transcription factor AP-1
107297859 ELK1; ETS domain-containing protein Elk-1
107302420 BTC; probetacellulin
107284145 HBEGF; proheparin-binding EGF-like growth factor
107302421 proepiregulin
107284855 ERBB3; receptor tyrosine-protein kinase erbB-3
107289677 NRG1; pro-neuregulin-1, membrane-bound isoform
107284140 NRG2; pro-neuregulin-2, membrane-bound isoform
107301863 ERBB4; receptor tyrosine-protein kinase erbB-4
107296691 SHC1; SHC-transforming protein 1
107298759 SHC-transforming protein 2-like
107293823 SHC3; SHC-transforming protein 3
107287682 SHC4; SHC-transforming protein 4
107292723 GRB2; growth factor receptor-bound protein 2
107296218 SOS2; son of sevenless homolog 2
107291909 SOS1; son of sevenless homolog 1
107287923 HRAS; GTPase HRas
107295639 KRAS; GTPase KRas isoform X1
107296269 GTPase HRas
107282493 GTPase HRas
107284053 NRAS; GTPase NRas
107297295 ARAF; serine/threonine-protein kinase A-Raf
107288626 BRAF; serine/threonine-protein kinase B-raf
107295520 RAF proto-oncogene serine/threonine-protein kinase isoform X1
107283932 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
107295320 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
107282702 mitogen-activated protein kinase 1-like
107293871 mitogen-activated protein kinase 1
107293420 MAPK1; mitogen-activated protein kinase 1
107299311 MYC; myc proto-oncogene protein
107292173 GAB1; GRB2-associated-binding protein 1
107298826 NRG3; pro-neuregulin-3, membrane-bound isoform
107285699 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
107292340 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
107284997 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
107292269 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
107282273 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
107283596 phosphatidylinositol 3-kinase regulatory subunit gamma
107286152 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
107292994 AKT3; RAC-gamma serine/threonine-protein kinase
107302433 AKT1; RAC-alpha serine/threonine-protein kinase
107285678 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
107294607 MTOR; serine/threonine-protein kinase mTOR
107298703 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
107293632 RPS6KB2; ribosomal protein S6 kinase beta-2
107299065 BAD; bcl2-associated agonist of cell death
107301245 bcl2-associated agonist of cell death-like
107286129 GSK3B; glycogen synthase kinase-3 beta
107286956 CDKN1B; cyclin-dependent kinase inhibitor 1B
107287054 CDKN1A; cyclin-dependent kinase inhibitor 1
107286965 cyclin-dependent kinase inhibitor 1
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K11224 STAT5B; signal transducer and activator of transcription 5B
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
|
04014 Ras signaling pathway
|
04015 Rap1 signaling pathway
|
04310 Wnt signaling pathway [PATH:pmur04310]
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04330 Notch signaling pathway [PATH:pmur04330]
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04340 Hedgehog signaling pathway [PATH:pmur04340]
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04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:pmur04350]
|
04390 Hippo signaling pathway
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species
|
04370 VEGF signaling pathway [PATH:pmur04370]
|
04371 Apelin signaling pathway [PATH:pmur04371]
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04630 JAK-STAT signaling pathway
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04064 NF-kappa B signaling pathway
|
04668 TNF signaling pathway
|
04066 HIF-1 signaling pathway
|
04068 FoxO signaling pathway [PATH:pmur04068]
|
107295274 TGFB1; transforming growth factor beta-1 proprotein
107299193 transforming growth factor beta-2 proprotein-like
107293669 TGFB2; transforming growth factor beta-2 proprotein
107285957 TGFB3; transforming growth factor beta-3 proprotein
107298532 TGF-beta receptor type-1
107299546 TGF-beta receptor type-1
107284378 TGFBR2; TGF-beta receptor type-2
107290268 TGF-beta receptor type-2
107284129 SMAD4; mothers against decapentaplegic homolog 4
107283914 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
107282874 STK11; serine/threonine-protein kinase STK11
107291127 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
107286634 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
107301177 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
107288822 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
107298009 5'-AMP-activated protein kinase subunit gamma-1-like
107293741 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1 isoform X1
107303313 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X1
107300808 5'-AMP-activated protein kinase subunit gamma-1
107294740 serine/threonine-protein kinase NLK2-like
107297926 NLK; serine/threonine-protein kinase NLK
107282732 serine/threonine-protein kinase NLK2-like
107297968 SKP2; S-phase kinase-associated protein 2
107284408 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
107293153 SETD7; histone-lysine N-methyltransferase SETD7
107283968 CREBBP; CREB-binding protein
107285414 EP300; histone acetyltransferase p300
107288080 SIRT1; NAD-dependent protein deacetylase sirtuin-1
107296635 USP7; ubiquitin carboxyl-terminal hydrolase 7
107298863 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
107294632 MAPK9; mitogen-activated protein kinase 9
107293954 MAPK8; mitogen-activated protein kinase 8 isoform X3
107303183 MAPK10; mitogen-activated protein kinase 10 isoform X1
107287815 STK4; serine/threonine-protein kinase 4
107289460 IGF1; insulin-like growth factor I
107290589 IGF1R; insulin-like growth factor 1 receptor
107294042 INS; insulin
107286667 IRS1; insulin receptor substrate 1
107298766 LOW QUALITY PROTEIN: insulin receptor substrate 2-B-like
107296125 IRS2; insulin receptor substrate 2
107285699 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
107292340 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
107284997 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
107292269 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
107282273 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
107283596 phosphatidylinositol 3-kinase regulatory subunit gamma
107286152 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
107302608 PDPK1; 3-phosphoinositide-dependent protein kinase 1
107291445 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
114923654 inhibitor of nuclear factor kappa-B kinase subunit alpha-like
107287960 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
107285111 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
107292994 AKT3; RAC-gamma serine/threonine-protein kinase
107302433 AKT1; RAC-alpha serine/threonine-protein kinase
107285678 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
107289907 SGK1; serine/threonine-protein kinase Sgk1 isoform X1
107290466 SGK2; serine/threonine-protein kinase Sgk2 isoform X1
107295114 serine/threonine-protein kinase Sgk3 isoform X1
107289857 FOXO1; forkhead box protein O1
107292237 forkhead box protein O3
107303214 FOXO4; forkhead box protein O4
107288028 forkhead box protein O3-like
107297679 HOMER2; homer protein homolog 2
107287872 HOMER1; homer protein homolog 1
107282858 HOMER3; homer protein homolog 3
107291498 AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
107288617 CSNK1E; casein kinase I
107282781 IL6; interleukin-6
107297703 IL10; interleukin-10
107282651 STAT3; signal transducer and activator of transcription 3 isoform X1
107290128 EGF; pro-epidermal growth factor
107284695 EGFR; epidermal growth factor receptor isoform X2
107292723 GRB2; growth factor receptor-bound protein 2
107296218 SOS2; son of sevenless homolog 2
107291909 SOS1; son of sevenless homolog 1
107287923 HRAS; GTPase HRas
107295639 KRAS; GTPase KRas isoform X1
107296269 GTPase HRas
107282493 GTPase HRas
107284053 NRAS; GTPase NRas
107288626 BRAF; serine/threonine-protein kinase B-raf
107295520 RAF proto-oncogene serine/threonine-protein kinase isoform X1
107297295 ARAF; serine/threonine-protein kinase A-Raf
107283932 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
107295320 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
107282702 mitogen-activated protein kinase 1-like
107293871 mitogen-activated protein kinase 1
107293420 MAPK1; mitogen-activated protein kinase 1
107292823 MAPK14; mitogen-activated protein kinase 14 isoform X1
107292825 MAPK13; mitogen-activated protein kinase 13
107286325 MAPK12; mitogen-activated protein kinase 12
107286326 MAPK11; mitogen-activated protein kinase 11
107287774 CDK2; cyclin-dependent kinase 2
107295837 protein arginine N-methyltransferase 1 isoform X1
107282500 protein arginine N-methyltransferase 1 isoform X1
107287627 FOXG1; forkhead box protein G1
107300638 CCNB1; G2/mitotic-specific cyclin-B1
107303272 CCNB3; G2/mitotic-specific cyclin-B3
107285821 CCND1; G1/S-specific cyclin-D1
107287828 CCNG2; cyclin-G2
107291620 CDKN2D; cyclin-dependent kinase 4 inhibitor D
107287054 CDKN1A; cyclin-dependent kinase inhibitor 1
107286965 cyclin-dependent kinase inhibitor 1
107286956 CDKN1B; cyclin-dependent kinase inhibitor 1B
107289912 RBL2; retinoblastoma-like protein 2
107299263 serine/threonine-protein kinase PLK1-like
107299990 serine/threonine-protein kinase PLK1-like
107286728 PLK2; serine/threonine-protein kinase PLK2
107283415 PLK3; serine/threonine-protein kinase PLK3
107290572 PLK4; serine/threonine-protein kinase PLK4 isoform X1
107299406 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
107296840 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
107302294 growth arrest and DNA damage-inducible protein GADD45 beta-like
107290157 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
107290564 FASLG; tumor necrosis factor ligand superfamily member 6
107291880 BCL2L11; bcl-2-like protein 11 isoform X2
107286546 TNFSF10; tumor necrosis factor ligand superfamily member 10
107298086 BCL6; B-cell lymphoma 6 protein
107284336 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
107290902 ATG12; ubiquitin-like protein ATG12
107292620 gamma-aminobutyric acid receptor-associated protein-like 1
107295344 GABARAP; gamma-aminobutyric acid receptor-associated protein
107283530 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1
107289608 CAT; catalase isoform X1
107289609 catalase-like isoform X2
107296817 SOD2; superoxide dismutase [Mn], mitochondrial
107284835 ATM; LOW QUALITY PROTEIN: serine-protein kinase ATM
107293099 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1
107292144 phosphoenolpyruvate carboxykinase, cytosolic [GTP]
107285920 glucose-6-phosphatase-like
107285935 glucose-6-phosphatase-like
107282655 G6PC3; glucose-6-phosphatase 3
107297967 IL7R; interleukin-7 receptor subunit alpha
107282212 KLF2; Krueppel-like factor 2
107302502 S1PR1; sphingosine 1-phosphate receptor 1
107295324 S1PR4; sphingosine 1-phosphate receptor 4
107293336 RAG1; LOW QUALITY PROTEIN: V(D)J recombination-activating protein 1
107293335 RAG2; V(D)J recombination-activating protein 2
107295162 FBXO32; F-box only protein 32
107284578 FBXO25; F-box only protein 25 isoform X1
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10146 CCNG2; cyclin G2
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
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04020 Calcium signaling pathway [PATH:pmur04020]
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04070 Phosphatidylinositol signaling system [PATH:pmur04070]
|
04072 Phospholipase D signaling pathway
|
04071 Sphingolipid signaling pathway
|
04024 cAMP signaling pathway
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04022 cGMP-PKG signaling pathway
|
04151 PI3K-Akt signaling pathway
|
04152 AMPK signaling pathway
|
04150 mTOR signaling pathway [PATH:pmur04150]
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04075 Plant hormone signal transduction
|
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09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
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09141 Transport and catabolism
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09143 Cell growth and death
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04110 Cell cycle [PATH:pmur04110]
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107285821 CCND1; G1/S-specific cyclin-D1
107293964 CCND3; G1/S-specific cyclin-D3
107291540 CDK4; cyclin-dependent kinase 4
107283642 CDK6; cyclin-dependent kinase 6
107284299 RB1; retinoblastoma-associated protein
107285577 RBL1; retinoblastoma-like protein 1
107289912 RBL2; retinoblastoma-like protein 2
107291344 ABL1; tyrosine-protein kinase ABL1
107297711 histone deacetylase 2
107285501 HDAC1; histone deacetylase 1
107294015 E2F1; transcription factor E2F1
107302908 E2F2; transcription factor E2F2
107302570 E2F3; transcription factor E2F3
107294439 E2F5; transcription factor E2F5
107288919 E2F4; transcription factor E2F4
107290436 TFDP1; transcription factor Dp-1
107286129 GSK3B; glycogen synthase kinase-3 beta
107295274 TGFB1; transforming growth factor beta-1 proprotein
107299193 transforming growth factor beta-2 proprotein-like
107293669 TGFB2; transforming growth factor beta-2 proprotein
107285957 TGFB3; transforming growth factor beta-3 proprotein
107283914 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
107284129 SMAD4; mothers against decapentaplegic homolog 4
107299311 MYC; myc proto-oncogene protein
107296447 ZBTB17; zinc finger and BTB domain-containing protein 17
107283071 CDKN2C; cyclin-dependent kinase 4 inhibitor C
107291620 CDKN2D; cyclin-dependent kinase 4 inhibitor D
107286956 CDKN1B; cyclin-dependent kinase inhibitor 1B
107298831 cyclin-dependent kinase inhibitor 1C
107287054 CDKN1A; cyclin-dependent kinase inhibitor 1
107286965 cyclin-dependent kinase inhibitor 1
107292735 CCNE1; G1/S-specific cyclin-E1
107289143 CCNE2; G1/S-specific cyclin-E2
107287774 CDK2; cyclin-dependent kinase 2
107294918 SKP1; S-phase kinase-associated protein 1
107288848 cullin-1
107285413 RBX1; E3 ubiquitin-protein ligase RBX1
107297968 SKP2; S-phase kinase-associated protein 2
107296600 CCNA2; cyclin-A2
107287659 CCNA1; cyclin-A1
107303083 CDC6; cell division control protein 6 homolog
107283479 CDT1; DNA replication factor Cdt1
107283069 ORC1; origin recognition complex subunit 1
107291760 ORC2; origin recognition complex subunit 2
107284741 ORC3; origin recognition complex subunit 3
107294302 ORC4; origin recognition complex subunit 4
107297208 origin recognition complex subunit 5
107300736 origin recognition complex subunit 5-like
107290114 ORC6; origin recognition complex subunit 6
107302449 MCM2; DNA replication licensing factor MCM2
107285564 MCM3; DNA replication licensing factor MCM3
107289323 MCM4; DNA replication licensing factor MCM4
107302638 MCM5; DNA replication licensing factor MCM5
107284389 MCM6; DNA replication licensing factor MCM6
107296115 MCM7; DNA replication licensing factor MCM7
107293411 CDC45; cell division control protein 45 homolog
107286854 TICRR; treslin
107296685 MTBP; mdm2-binding protein
107294837 CDC7; cell division cycle 7-related protein kinase
107283304 DBF4; protein DBF4 homolog A
107297330 CDK1; cyclin-dependent kinase 1
107300638 CCNB1; G2/mitotic-specific cyclin-B1
107303272 CCNB3; G2/mitotic-specific cyclin-B3
107297885 CDC25B; M-phase inducer phosphatase 2
107299702 M-phase inducer phosphatase 1-A-like
107289189 CDC25C; M-phase inducer phosphatase 3
107295814 YWHAQ; 14-3-3 protein theta
107287813 14-3-3 protein beta/alpha
107285186 14-3-3 protein zeta/delta
107289560 YWHAE; 14-3-3 protein epsilon
107294564 YWHAG; 14-3-3 protein gamma
107299263 serine/threonine-protein kinase PLK1-like
107299990 serine/threonine-protein kinase PLK1-like
107293506 WEE1; wee1-like protein kinase
107290166 WEE2; wee1-like protein kinase 2
107296267 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
107282525 PKMYT1; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
107302941 CCNH; cyclin-H isoform X1
107300936 cyclin-H-like
107300604 CDK7; cyclin-dependent kinase 7
107291896 ANAPC1; anaphase-promoting complex subunit 1
107302520 ANAPC2; anaphase-promoting complex subunit 2
107294047 cell division cycle protein 27 homolog
107303057 cell division cycle protein 27 homolog isoform X1
107297773 ANAPC4; anaphase-promoting complex subunit 4
107287010 ANAPC5; anaphase-promoting complex subunit 5
107287914 CDC16; cell division cycle protein 16 homolog
107285451 ANAPC7; anaphase-promoting complex subunit 7
107294702 CDC23; cell division cycle protein 23 homolog
107286198 ANAPC10; anaphase-promoting complex subunit 10 isoform X1
107295824 ANAPC11; anaphase-promoting complex subunit 11
107302814 CDC26; anaphase-promoting complex subunit CDC26 isoform X1
107287133 ANAPC13; anaphase-promoting complex subunit 13
107299756 anaphase-promoting complex subunit 15 isoform X2
107297404 anaphase-promoting complex subunit 15 isoform X2
107288089 ANAPC16; anaphase-promoting complex subunit 16
107283451 CDC20; cell division cycle protein 20 homolog
107286897 PTTG1; securin
107288516 ESPL1; separin
107284211 SMC1A; structural maintenance of chromosomes protein 1A
107294343 SMC1B; structural maintenance of chromosomes protein 1B
107289368 SMC3; structural maintenance of chromosomes protein 3
107288217 RAD21; double-strand-break repair protein rad21 homolog
114923121 double-strand-break repair protein rad21-like protein 1
107284250 cohesin subunit SA-2
107297408 cohesin subunit SA-2
107290043 cohesin subunit SA-1
107298604 cohesin subunit SA-2
107284622 ATRX; transcriptional regulator ATRX
107297812 DDX11; ATP-dependent DNA helicase DDX11
107288336 NIPBL; nipped-B-like protein
107285279 MAU2; MAU2 chromatid cohesion factor homolog
107303234 HDAC8; histone deacetylase 8
107291600 ESCO1; N-acetyltransferase ESCO1
107291038 ESCO2; N-acetyltransferase ESCO2
107286808 PDS5B; sister chromatid cohesion protein PDS5 homolog B
107302804 PDS5A; sister chromatid cohesion protein PDS5 homolog A
107294227 WAPL; LOW QUALITY PROTEIN: wings apart-like protein homolog
107295991 CDCA5; sororin
107294711 aurora kinase B-B-like
107297101 aurora kinase B-B
107282899 SGO1; shugoshin 1
107294933 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
107285618 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
107295075 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
107295367 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1
107295995 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
107293312 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
107297200 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
107286334 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
114923370 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform-like
107285290 NDC80; kinetochore protein NDC80 homolog
114922489 KNL1; kinetochore scaffold 1
107288222 TTK; dual specificity protein kinase TTK
107290612 MAD1L1; mitotic spindle assembly checkpoint protein MAD1
107289776 MAD2L1; mitotic spindle assembly checkpoint protein MAD2A
107294162 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
107285939 BUB3; mitotic checkpoint protein BUB3 isoform X1
107290416 BUB1; mitotic checkpoint serine/threonine-protein kinase BUB1
107298521 TRIP13; pachytene checkpoint protein 2 homolog
107289285 MAD2L1BP; MAD2L1-binding protein
107282246 FZR1; fizzy-related protein homolog
107292876 FBXO5; F-box only protein 5
107302495 CDC14A; dual specificity protein phosphatase CDC14A
107283968 CREBBP; CREB-binding protein
107285414 EP300; histone acetyltransferase p300
107287153 PRKDC; LOW QUALITY PROTEIN: DNA-dependent protein kinase catalytic subunit
107292039 ATR; serine/threonine-protein kinase ATR
107284835 ATM; LOW QUALITY PROTEIN: serine-protein kinase ATM
107284408 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
107299049 cellular tumor antigen p53-like
107299406 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
107296840 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
107302294 growth arrest and DNA damage-inducible protein GADD45 beta-like
107290157 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
107283633 PCNA; proliferating cell nuclear antigen
107289897 SFN; 14-3-3 protein sigma
107296402 serine/threonine-protein kinase Chk1
107296403 serine/threonine-protein kinase Chk1-like
107287280 CHEK2; serine/threonine-protein kinase Chk2
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K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
K06628 CDC45; cell division control protein 45
K26117 TICRR; Treslin
K26116 MTBP; Mdm2-binding protein
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 DBF4; protein DBF4
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K10779 ATRX; transcriptional regulator ATRX
K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
K06672 SCC2; cohesin loading factor subunit SCC2
K11266 MAU2; MAternally affected uncoordination
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11267 PDS5; sister chromatid cohesion protein PDS5
K11267 PDS5; sister chromatid cohesion protein PDS5
K25163 WAPL; wings apart-like protein
K17390 CDCA5; sororin
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11580 SGOL1; shugoshin-like 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11547 NDC80; kinetochore protein NDC80
K11542 CASC5; protein CASC5
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K02180 BUB3; cell cycle arrest protein BUB3
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K22399 TRIP13; pachytene checkpoint protein 2
K26093 MAD2L1BP; MAD2L1-binding protein
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K10292 FBXO5; F-box protein 5
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
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04111 Cell cycle - yeast
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04112 Cell cycle - Caulobacter
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04113 Meiosis - yeast
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04114 Oocyte meiosis [PATH:pmur04114]
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04210 Apoptosis [PATH:pmur04210]
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04214 Apoptosis - fly
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04215 Apoptosis - multiple species
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04216 Ferroptosis [PATH:pmur04216]
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04217 Necroptosis [PATH:pmur04217]
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04115 p53 signaling pathway [PATH:pmur04115]
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04218 Cellular senescence [PATH:pmur04218]
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09144 Cellular community - eukaryotes
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09145 Cellular community - prokaryotes
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09142 Cell motility
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Protobothrops mucrosquamatus (Taiwan habu)