KEGG   PATHWAY: epz04060
Entry
epz04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Equus przewalskii (Przewalski's horse)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
epz04060  Cytokine-cytokine receptor interaction
epz04060

Organism
Equus przewalskii (Przewalski's horse) [GN:epz]
Gene
103540014  IL20RB; interleukin-20 receptor subunit beta isoform X1 [KO:K05137]
103540202  [KO:K16595]
103540203  [KO:K16596]
103540302  [KO:K05447]
103540324  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
103540728  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
103540862  INHA; inhibin alpha chain isoform X1 [KO:K05500]
103540970  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
103541234  IL31; interleukin-31 [KO:K22631]
103541352  EDA; ectodysplasin-A isoform X1 [KO:K05480]
103541553  CD40LG; CD40 ligand isoform X1 [KO:K03161]
103541620  IL10; interleukin-10 [KO:K05443]
103541978  IL17C; interleukin-17C [KO:K05491]
103542210  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
103542488  IL13RA2; interleukin-13 receptor subunit alpha-2 isoform X2 [KO:K05077]
103542573  EPOR; erythropoietin receptor [KO:K05079]
103542627  CCL19; C-C motif chemokine 19 [KO:K05512]
103542629  CCL27; C-C motif chemokine 27 [KO:K16598]
103542631  GALT; galactose-1-phosphate uridylyltransferase isoform X3 [KO:K05056]
103542787  LEP; leptin [KO:K05424]
103542816  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
103542987  EBI3; interleukin-27 subunit beta [KO:K24476]
103543045  TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
103543272  [KO:K14624]
103543483  IL9; interleukin-9 [KO:K05432]
103543552  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
103543844  CCL25; C-C motif chemokine 25 [KO:K13072]
103543851  CRLF2; cytokine receptor-like factor 2 isoform X1 [KO:K05078]
103543888  IL24; interleukin-24 [KO:K22668]
103543998  CCL21; C-C motif chemokine 21 [KO:K16062]
103544116  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
103544207  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
103544216  TNFSF4; tumor necrosis factor ligand superfamily member 4 isoform X1 [KO:K05469]
103544371  IL20; interleukin-20 [KO:K22667]
103544407  [KO:K04738]
103544458  AMH; muellerian-inhibiting factor [KO:K04665]
103544471  [KO:K05152]
103544584  [KO:K05414]
103544587  GDF7; growth/differentiation factor 7 [KO:K20013]
103544610  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
103544644  [KO:K05509]
103544677  EDA2R; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 27 [KO:K05163]
103544835  [KO:K04519]
103544971  [KO:K16597]
103545152  [KO:K22669]
103545274  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1 [KO:K05066]
103545318  [KO:K05152]
103545339  PRLR; prolactin receptor [KO:K05081]
103545416  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
103545473  [KO:K04519]
103545812  [KO:K05505]
103546082  IL11; interleukin-11 [KO:K05417]
103546134  [KO:K05152]
103546142  [KO:K05447]
103546356  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X2 [KO:K04721]
103546383  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
103546663  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
103546683  IL10RA; interleukin-10 receptor subunit alpha isoform X1 [KO:K05134]
103546993  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
103546995  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
103546996  CD27; CD27 antigen isoform X1 [KO:K05144]
103547015  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
103547099  CCR8; C-C chemokine receptor type 8 [KO:K04183]
103547269  [KO:K24382]
103547400  IL7; interleukin-7 isoform X1 [KO:K05431]
103547498  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
103547705  CCR6; C-C chemokine receptor type 6 [KO:K04181]
103547744  NGF; beta-nerve growth factor [KO:K02582]
103547779  IL12B; interleukin-12 subunit beta [KO:K05425]
103547840  BMP5; bone morphogenetic protein 5 isoform X2 [KO:K04663]
103548080  OSM; oncostatin-M [KO:K05418]
103548085  LIF; leukemia inhibitory factor [KO:K05419]
103548203  IL31RA; interleukin-31 receptor subunit alpha isoform X1 [KO:K22630]
103548204  IL6ST; interleukin-6 receptor subunit beta isoform X3 [KO:K05060]
103548644  MSTN; growth/differentiation factor 8 [KO:K05497]
103548896  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
103548904  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
103548930  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
103548967  BMP10; bone morphogenetic protein 10 [KO:K22670]
103549040  BMP3; bone morphogenetic protein 3 [KO:K05496]
103549042  IL20RA; LOW QUALITY PROTEIN: interleukin-20 receptor subunit alpha [KO:K05136]
103549045  IFNGR1; interferon gamma receptor 1 [KO:K05132]
103549109  IFNGR2; interferon gamma receptor 2 isoform X1 [KO:K05133]
103549120  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
103549136  [KO:K05131]
103549146  IL15; interleukin-15 isoform X3 [KO:K05433]
103549220  BMPR2; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
103549278  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
103549321  BMP6; bone morphogenetic protein 6 [KO:K16620]
103549480  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
103549756  [KO:K05438]
103549990  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
103550169  CSF3; granulocyte colony-stimulating factor isoform X2 [KO:K05423]
103550183  CCR7; C-C chemokine receptor type 7 [KO:K04182]
103550188  IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067]
103550285  IFNK; interferon kappa [KO:K05441]
103550353  CCR10; C-C chemokine receptor type 10 isoform X2 [KO:K04185]
103550405  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
103550694  RELL2; RELT-like protein 2 [KO:K26541]
103550833  IL17F; interleukin-17F [KO:K05494]
103550834  IL17A; interleukin-17A [KO:K05489]
103551072  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
103551613  IL32; interleukin-32 isoform X1 [KO:K22632]
103551646  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
103551918  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
103552189  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141]
103552190  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X1 [KO:K05145]
103552411  IL34; interleukin-34 isoform X1 [KO:K22633]
103552761  [KO:K04722]
103552800  RELL1; RELT-like protein 1 isoform X1 [KO:K26541]
103552975  IL16; pro-interleukin-16 isoform X1 [KO:K22628]
103553842  GHR; growth hormone receptor isoform X1 [KO:K05080]
103554252  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
103554403  ACVR1; activin receptor type-1 isoform X1 [KO:K04675] [EC:2.7.11.30]
103554404  ACVR1C; activin receptor type-1C isoform X1 [KO:K13568] [EC:2.7.11.30]
103554436  GDF5; growth/differentiation factor 5 [KO:K04664]
103554508  CCL5; C-C motif chemokine 5 [KO:K12499]
103554509  CCL16; C-C motif chemokine 16 isoform X2 [KO:K21093]
103554510  [KO:K21092]
103554511  CCL15; C-C motif chemokine 15 isoform X1 [KO:K05511]
103554513  [KO:K05408]
103554514  [KO:K12964]
103554738  THPO; thrombopoietin isoform X1 [KO:K06854]
103555067  CCR9; C-C chemokine receptor type 9 [KO:K04184]
103555069  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
103555071  XCR1; chemokine XC receptor 1 [KO:K04193]
103555072  CCR1; C-C chemokine receptor type 1 [KO:K04176]
103555073  CCR3; C-C chemokine receptor type 3 [KO:K04178]
103555075  [KO:K04177]
103555098  PRL; prolactin isoform X2 [KO:K05439]
103555107  GDF6; growth/differentiation factor 6 [KO:K20012]
103555266  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
103555269  OSMR; oncostatin-M-specific receptor subunit beta isoform X3 [KO:K05057]
103555314  LIFR; leukemia inhibitory factor receptor [KO:K05058]
103555378  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
103555388  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
103555416  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
103555506  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
103555655  EPO; erythropoietin [KO:K05437]
103556252  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
103556288  IL17B; interleukin-17B isoform X1 [KO:K05490]
103556346  IL21R; interleukin-21 receptor isoform X1 [KO:K05075]
103556347  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
103556353  [KO:K05485]
103556354  IL37; interleukin-37 isoform X1 [KO:K05485]
103556355  IL36G; interleukin-36 gamma [KO:K05487]
103556356  IL36B; interleukin-36 beta [KO:K05486]
103556358  IL1F10; interleukin-1 family member 10 [KO:K05488]
103556359  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
103556360  IL1RN; interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
103556364  [KO:K05484]
103556575  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
103556650  GDF3; growth/differentiation factor 3 [KO:K22672]
103556759  IL25; interleukin-25 [KO:K05493]
103557031  INHBA; inhibin beta A chain [KO:K04667]
103557055  BMPR1B; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
103557150  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
103557421  MPL; thrombopoietin receptor [KO:K05082]
103557529  CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453]
103557547  IL23A; interleukin-23 subunit alpha [KO:K05426]
103557654  GDF2; growth/differentiation factor 2 [KO:K05503]
103557661  GDF10; growth/differentiation factor 10 [KO:K22674]
103557668  CX3CR1; CX3C chemokine receptor 1 isoform X2 [KO:K04192]
103557715  TNFSF12; tumor necrosis factor ligand superfamily member 12 isoform X2 [KO:K05474]
103557716  TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X2 [KO:K05475]
103557771  BMP7; bone morphogenetic protein 7 [KO:K16621]
103557874  IL2; interleukin-2 [KO:K05429]
103557875  IL21; interleukin-21 [KO:K05434]
103558124  FAS; tumor necrosis factor receptor superfamily member 6 isoform X2 [KO:K04390]
103558557  TNFRSF18; tumor necrosis factor receptor superfamily member 18 [KO:K05154]
103558558  TNFRSF4; tumor necrosis factor receptor superfamily member 4 isoform X1 [KO:K05142]
103558707  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
103558745  IFNE; interferon epsilon [KO:K05442]
103558746  [KO:K05440]
103558747  [KO:K05414]
103558748  [KO:K05414]
103558749  [KO:K05414]
103558750  [KO:K05414]
103559209  IL22; interleukin-22 [KO:K05445]
103559218  IL1R2; interleukin-1 receptor type 2 isoform X1 [KO:K04387]
103559269  IL26; LOW QUALITY PROTEIN: interleukin-26 [KO:K05446]
103559339  IFNG; interferon gamma [KO:K04687]
103559401  AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 [KO:K04672] [EC:2.7.11.30]
103559565  IL23R; interleukin-23 receptor isoform X2 [KO:K05065]
103559649  TNFRSF19; tumor necrosis factor receptor superfamily member 19 [KO:K05155]
103559673  IL1A; interleukin-1 alpha isoform X1 [KO:K04383]
103559787  INHBE; inhibin beta E chain [KO:K22689]
103559788  INHBC; inhibin beta C chain [KO:K22688]
103559875  CLCF1; cardiotrophin-like cytokine factor 1 isoform X1 [KO:K05421]
103560147  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
103560213  GDF11; growth/differentiation factor 11 [KO:K22679]
103560329  ACKR4; atypical chemokine receptor 4 isoform X1 [KO:K04186]
103560357  INHBB; inhibin beta B chain [KO:K22687]
103560371  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
103560539  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X2 [KO:K05160]
103560670  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
103560752  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
103560775  CCL24; C-C motif chemokine 24 [KO:K21097]
103560776  CCL26; C-C motif chemokine 26 [KO:K21096]
103561072  ACVR2B; activin receptor type-2B isoform X1 [KO:K13596] [EC:2.7.11.30]
103561087  RELT; tumor necrosis factor receptor superfamily member 19L [KO:K05156]
103561101  CCR4; C-C chemokine receptor type 4 isoform X2 [KO:K04179]
103561141  IL6; interleukin-6 [KO:K05405]
103561300  ACVR1B; activin receptor type-1B isoform X1 [KO:K13567] [EC:2.7.11.30]
103561301  ACVRL1; activin receptor type-1-like isoform X1 [KO:K13594] [EC:2.7.11.30]
103561544  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
103561644  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
103561655  CXCL12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
103561707  TNFRSF9; tumor necrosis factor receptor superfamily member 9 isoform X1 [KO:K05146]
103561711  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
103561906  IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
103561912  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
103562028  CNTF; ciliary neurotrophic factor [KO:K05420]
103562153  CCL28; C-C motif chemokine 28 [KO:K05513]
103562216  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
103562217  CXCL11; C-X-C motif chemokine 11 [KO:K12672]
103562220  CXCL9; C-X-C motif chemokine 9 [KO:K05416]
103562285  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B [KO:K05143]
103562372  IL18RAP; interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
103562374  IL18R1; interleukin-18 receptor 1 [KO:K05173]
103562375  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
103562469  TNF; tumor necrosis factor isoform X1 [KO:K03156]
103562471  LTA; lymphotoxin-alpha [KO:K05468]
103562494  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
103562543  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
103562575  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A isoform X1 [KO:K05147]
103562703  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C isoform X1 [KO:K05151]
103562740  IL27; interleukin-27 subunit alpha [KO:K22629]
103562911  IL12A; interleukin-12 subunit alpha [KO:K05406]
103563025  NODAL; nodal homolog isoform X1 [KO:K04666]
103563129  IL9R; interleukin-9 receptor isoform X1 [KO:K05073]
103563132  GDF9; growth/differentiation factor 9 [KO:K22673]
103563147  [KO:K05415]
103563148  IFNB1; interferon beta [KO:K05415]
103563150  [KO:K05415]
103563151  [KO:K05440]
103563154  [KO:K05414]
103563181  IL1RL2; interleukin-1 receptor-like 2 isoform X4 [KO:K05172]
103563182  IL13; interleukin-13 isoform X1 [KO:K05435]
103563183  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
103563197  IL5; interleukin-5 [KO:K05428]
103563310  TSLP; thymic stromal lymphopoietin isoform X2 [KO:K05436]
103563367  IL4; interleukin-4 isoform X1 [KO:K05430]
103563743  IL33; interleukin-33 isoform X1 [KO:K12967]
103563779  BMP2; bone morphogenetic protein 2 [KO:K21283]
103563811  IL17RA; interleukin-17 receptor A [KO:K05164]
103563974  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
103564145  [KO:K05050]
103564146  [KO:K04175]
103564325  BMP8B; bone morphogenetic protein 8B isoform X1 [KO:K16622]
103564365  CNTFR; ciliary neurotrophic factor receptor subunit alpha [KO:K05059]
103564462  IL2RB; interleukin-2 receptor subunit beta isoform X2 [KO:K05069]
103564852  IL1RAP; interleukin-1 receptor accessory protein isoform X2 [KO:K04723]
103564968  CCL22; C-C motif chemokine 22 [KO:K21095]
103564970  CX3CL1; fractalkine isoform X2 [KO:K05508]
103564971  CCL17; C-C motif chemokine 17 isoform X2 [KO:K21083]
103565356  ACKR3; atypical chemokine receptor 3 [KO:K04304]
103565541  CD70; CD70 antigen [KO:K05470]
103565543  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
103565731  XCL1; lymphotactin [KO:K05507]
103565789  [KO:K05505]
103565792  [KO:K05505]
103565880  IL18; interleukin-18 [KO:K05482]
103565960  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
103565964  LEPR; leptin receptor isoform X1 [KO:K05062]
103566034  [KO:K22669]
103566680  IFNLR1; interferon lambda receptor 1 isoform X2 [KO:K05140]
103566681  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
103566765  [KO:K05407]
103566766  PPBP; platelet basic protein [KO:K10029]
103566767  CXCL6; C-X-C motif chemokine 6 [KO:K05506]
103566768  CXCL8; interleukin-8 [KO:K10030]
103566821  BMP15; bone morphogenetic protein 15 [KO:K05498]
103567211  CCR5; C-C chemokine receptor type 5 [KO:K04180]
103567708  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
103567783  [KO:K05133]
103567851  [KO:K05440]
103567852  [KO:K05440]
103567855  [KO:K05414]
103567857  [KO:K05440]
139073705  [KO:K22669]
139075665  [KO:K04519]
139077781  GDF15; growth/differentiation factor 15 [KO:K05504]
139077784  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
139078371  [KO:K05414]
139078389  [KO:K05440]
139078428  [KO:K05414]
139078534  [KO:K05414]
139078539  [KO:K05440]
139078605  [KO:K05512]
139078652  [KO:K16598]
139078706  [KO:K05414]
139078849  IL19; LOW QUALITY PROTEIN: interleukin-19 [KO:K05444]
139081867  [KO:K04722]
Reference
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
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