KEGG   PATHWAY: epz04024
Entry
epz04024                    Pathway                                
Name
cAMP signaling pathway - Equus przewalskii (Przewalski's horse)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
epz04024  cAMP signaling pathway
epz04024

Other DBs
GO: 0019933
Organism
Equus przewalskii (Przewalski's horse) [GN:epz]
Gene
103540011  F2R; proteinase-activated receptor 1 isoform X1 [KO:K03914]
103540249  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103540380  VAV1; proto-oncogene vav [KO:K05730]
103540718  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
103540766  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
103540802  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
103540947  [KO:K05250]
103540948  FSHB; LOW QUALITY PROTEIN: follitropin subunit beta [KO:K05250]
103540984  SSTR5; somatostatin receptor type 5 [KO:K04221]
103541373  [KO:K16056]
103541380  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
103541478  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
103541647  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
103541706  CRHR2; corticotropin-releasing factor receptor 2 isoform X1 [KO:K04579]
103541710  PDE4A; 3',5'-cyclic-AMP phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
103542187  BAD; bcl2-associated agonist of cell death [KO:K02158]
103542519  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
103543290  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103543692  RELA; transcription factor p65 [KO:K04735]
103543741  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 isoform X1 [KO:K01539] [EC:7.2.2.13]
103543855  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
103543955  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
103544458  AMH; muellerian-inhibiting factor [KO:K04665]
103544963  CALM3; calmodulin-3 [KO:K02183]
103544999  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
103545235  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
103545804  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
103546357  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
103546360  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
103546400  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
103546599  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
103546604  GRIN2C; glutamate receptor ionotropic, NMDA 2C isoform X1 [KO:K05211]
103546727  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
103546793  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X5 [KO:K08014]
103547036  [KO:K04632]
103547082  AFDN; afadin isoform X1 [KO:K05702]
103547261  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
103547313  GRIA2; glutamate receptor 2 isoform X2 [KO:K05198]
103547349  PDE4D; 3',5'-cyclic-AMP phosphodiesterase 4D isoform X3 [KO:K13293] [EC:3.1.4.53]
103547403  SSTR2; somatostatin receptor type 2 isoform X1 [KO:K04218]
103547408  SOX9; transcription factor SOX-9 [KO:K18435]
103547421  POPDC2; popeye domain-containing protein 2 isoform X2 [KO:K26206]
103547555  VIP; VIP peptides isoform X2 [KO:K05264]
103547739  TSHB; thyrotropin subunit beta [KO:K05251]
103547749  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 isoform X2 [KO:K01539] [EC:7.2.2.13]
103547762  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
103547763  CGA; glycoprotein hormones alpha chain [KO:K08522]
103547802  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
103547816  POMC; pro-opiomelanocortin isoform X2 [KO:K05228]
103547823  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
103547847  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
103548220  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
103548407  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X6 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
103548618  FOS; protein c-Fos [KO:K04379]
103548764  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X7 [KO:K01538]
103548885  CALML5; calmodulin-like protein 5 [KO:K02183]
103548886  [KO:K02183]
103548908  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
103548994  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X5 [KO:K04260]
103549012  NPY; pro-neuropeptide Y [KO:K05232]
103549076  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
103549121  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
103549414  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
103549465  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
103549472  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
103549491  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X11 [KO:K09047]
103549596  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
103549616  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
103549630  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [KO:K04368] [EC:2.7.12.2]
103549680  GRIA1; glutamate receptor 1 isoform X2 [KO:K05197]
103549870  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
103549871  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
103549904  GRIN2B; glutamate receptor ionotropic, NMDA 2B isoform X1 [KO:K05210]
103549905  CALM1; calmodulin-1 isoform X1 [KO:K02183]
103549928  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
103550069  CAMK4; calcium/calmodulin-dependent protein kinase type IV isoform X1 [KO:K05869] [EC:2.7.11.17]
103550104  VAV3; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
103550158  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
103550239  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 isoform X1 [KO:K04615]
103550316  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
103550430  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
103550531  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
103550555  TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
103550588  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
103550596  PDE4B; 3',5'-cyclic-AMP phosphodiesterase 4B isoform X2 [KO:K13293] [EC:3.1.4.53]
103550601  CFTR; cystic fibrosis transmembrane conductance regulator isoform X1 [KO:K05031] [EC:5.6.1.6]
103550654  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
103550695  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
103551104  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
103551135  [KO:K01539] [EC:7.2.2.13]
103551139  [KO:K01539] [EC:7.2.2.13]
103551292  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
103551335  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
103551549  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
103551629  SUCNR1; succinate receptor 1 isoform X1 [KO:K10042]
103551694  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
103551868  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
103552141  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
103552150  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103552182  NPPA; natriuretic peptides A [KO:K12334]
103552436  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
103552461  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
103552470  CRH; corticoliberin [KO:K05256]
103552694  BDNF; neurotrophic factor BDNF precursor form isoform X2 [KO:K04355]
103552805  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
103552897  EDN1; endothelin-1 [KO:K16366]
103552912  CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
103552981  ADRB2; beta-2 adrenergic receptor [KO:K04142]
103552982  HTR4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
103553014  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
103553025  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
103553052  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
103553307  [KO:K08521]
103553409  RHOA; transforming protein RhoA [KO:K04513]
103553524  CNGA4; cyclic nucleotide-gated channel alpha-4 isoform X2 [KO:K04951]
103553551  EDN2; endothelin-2 [KO:K16367]
103553799  PAK1; serine/threonine-protein kinase PAK 1 isoform X2 [KO:K04409] [EC:2.7.11.1]
103553980  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
103553985  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
103554178  RYR2; ryanodine receptor 2 [KO:K04962]
103554289  CNGA3; cyclic nucleotide-gated channel alpha-3 isoform X3 [KO:K04950]
103554419  GCG; pro-glucagon isoform X1 [KO:K05259]
103554541  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
103554763  EDN3; endothelin-3 isoform X1 [KO:K05227]
103554952  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
103555005  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
103555122  ADORA1; adenosine receptor A1 [KO:K04265]
103555146  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
103555338  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
103555399  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2 [KO:K09048]
103555421  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
103555422  FSHR; follicle-stimulating hormone receptor isoform X3 [KO:K04247]
103555495  [KO:K11265] [EC:4.6.1.1]
103555691  EDNRA; endothelin-1 receptor [KO:K04197]
103555780  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
103556116  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
103556250  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
103556685  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
103556719  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
103556909  LHCGR; lutropin-choriogonadotropic hormone receptor isoform X1 [KO:K04248]
103557126  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
103557268  SST; somatostatin [KO:K05237]
103557289  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
103557343  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
103557390  GRIA3; glutamate receptor 3 isoform X2 [KO:K05199]
103557393  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
103557622  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
103557709  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 isoform X1 [KO:K01540]
103557854  CNGB1; cyclic nucleotide-gated channel beta-1 [KO:K04952]
103557936  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform X1 [KO:K13296] [EC:3.1.4.17]
103558105  CALM2; calmodulin-2 [KO:K02183]
103558311  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
103558687  RAP1B; ras-related protein Rap-1b [KO:K07836]
103558823  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
103558955  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
103559121  OXTR; oxytocin receptor [KO:K04229]
103559134  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
103559297  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
103559312  GIP; gastric inhibitory polypeptide [KO:K05258]
103559319  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
103559362  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
103559377  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
103559592  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
103559610  PLN; phospholamban [KO:K05852]
103559782  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
103560040  FFAR2; free fatty acid receptor 2 [KO:K04328]
103560108  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
103560150  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
103560297  CREB3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3 [KO:K09048]
103560346  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
103560497  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103560615  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
103560664  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
103560690  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
103560754  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
103561050  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
103561286  CNGA1; cyclic nucleotide-gated channel alpha-1 [KO:K04948]
103561369  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
103561465  GHRL; appetite-regulating hormone [KO:K05254]
103561469  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
103561541  PDE4C; 3',5'-cyclic-AMP phosphodiesterase 4C isoform X2 [KO:K13293] [EC:3.1.4.53]
103561550  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
103561852  ADORA2A; adenosine receptor A2a [KO:K04266]
103561876  POPDC3; popeye domain-containing protein 3 [KO:K26207]
103561877  POPDC1; blood vessel epicardial substance [KO:K21108]
103561891  TSHR; thyrotropin receptor isoform X1 [KO:K04249]
103562408  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103562505  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
103562734  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [KO:K05853] [EC:7.2.2.10]
103562864  TNNI3; troponin I, cardiac muscle [KO:K12044]
103563075  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
103563588  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
103563634  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
103563810  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
103563830  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
103564042  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
103564053  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
103564266  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
103564464  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
103564708  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
103564820  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
103565080  VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
103565109  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
103565152  DRD1; D(1A) dopamine receptor [KO:K04144]
103565240  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
103565402  [KO:K04632]
103565780  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
103565953  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
103566021  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
103566499  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
103566725  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
103567070  DRD5; D(1B) dopamine receptor [KO:K05840]
103567330  ABCC4; ATP-binding cassette sub-family C member 4 [KO:K05673]
103567387  RRAS2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
103567415  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
103567454  CNGA2; cyclic nucleotide-gated channel alpha-2 [KO:K04949]
103567623  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
103567629  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
103567632  CNGB3; cyclic nucleotide-gated channel beta-3 [KO:K04953]
103567933  DRD2; D(2) dopamine receptor [KO:K04145]
139078096  OXT; oxytocin-neurophysin 1 [KO:K05243]
139080209  ADRB1; beta-1 adrenergic receptor [KO:K04141]
139081849  [KO:K02183]
139081876  JUN; transcription factor Jun [KO:K04448]
139082425  [KO:K04353]
139084055  GRIN3B; glutamate receptor ionotropic, NMDA 3B isoform X1 [KO:K05214]
139085512  RRAS; ras-related protein R-Ras [KO:K07829]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
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Related
pathway
epz00071  Fatty acid degradation
epz04015  Rap1 signaling pathway
epz04020  Calcium signaling pathway
epz04151  PI3K-Akt signaling pathway
epz04210  Apoptosis
epz04260  Cardiac muscle contraction
epz04340  Hedgehog signaling pathway
epz04720  Long-term potentiation
epz04740  Olfactory transduction
epz04972  Pancreatic secretion
epz04976  Bile secretion
KO pathway
ko04024   

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