KEGG   PATHWAY: pviv04024
Entry
pviv04024                   Pathway                                
Name
cAMP signaling pathway - Prionailurus viverrinus (fishing cat)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
pviv04024  cAMP signaling pathway
pviv04024

Other DBs
GO: 0019933
Organism
Prionailurus viverrinus (fishing cat) [GN:pviv]
Gene
125166267  VIP; VIP peptides [KO:K05264]
125156479  CRH; corticoliberin [KO:K05256]
125166053  CGA; glycoprotein hormones alpha chain [KO:K08522]
125153004  LHB; lutropin subunit beta [KO:K08521]
125146602  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
125167347  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
125172765  TSHB; thyrotropin subunit beta [KO:K05251]
125162078  POMC; pro-opiomelanocortin [KO:K05228]
125173596  GCG; pro-glucagon isoform X1 [KO:K05259]
125158696  GIP; gastric inhibitory polypeptide [KO:K05258]
125146636  follitropin subunit beta [KO:K05250]
125171797  NPPA; natriuretic peptides A [KO:K12334]
125149343  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
125147928  ADRB1; beta-1 adrenergic receptor [KO:K04141]
125177252  ADRB2; beta-2 adrenergic receptor [KO:K04142]
125168805  DRD1; D(1A) dopamine receptor [KO:K04144]
125163321  DRD5; D(1B) dopamine receptor [KO:K05840]
125149272  ADORA2A; adenosine receptor A2a isoform X1 [KO:K04266]
125167640  HTR4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
125172506  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
125168190  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
125161020  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
125160192  VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
125151549  CRHR1; corticotropin-releasing factor receptor 1 [KO:K04578]
125161280  CRHR2; corticotropin-releasing factor receptor 2 [KO:K04579]
125161884  LHCGR; lutropin-choriogonadotropic hormone receptor isoform X1 [KO:K04248]
125168242  TSHR; thyrotropin receptor [KO:K04249]
125149571  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
125166311  GLP1R; glucagon-like peptide 1 receptor isoform X1 [KO:K04581]
125153025  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
125157798  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
125162931  FSHR; LOW QUALITY PROTEIN: follicle-stimulating hormone receptor [KO:K04247]
125155033  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
125161530  neuroendocrine secretory protein 55 [KO:K04632]
125161813  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
125165176  EDN1; endothelin-1 [KO:K16366]
125173412  EDN2; endothelin-2 isoform X1 [KO:K16367]
125163018  EDN3; endothelin-3 isoform X1 [KO:K05227]
125175740  SST; somatostatin [KO:K05237]
125160854  NPY; pro-neuropeptide Y [KO:K05232]
125150980  GHRL; appetite-regulating hormone isoform X1 [KO:K05254]
125162526  OXT; oxytocin-neurophysin 1 [KO:K05243]
125173592  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
125166701  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
125166753  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
125173135  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
125175160  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
125175985  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
125160698  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
125147028  DRD2; D(2) dopamine receptor isoform X1 [KO:K04145]
125150955  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
125159849  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
125155629  ADORA1; adenosine receptor A1 [KO:K04265]
125164248  EDNRA; endothelin-1 receptor [KO:K04197]
125164561  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
125167991  SSTR1; somatostatin receptor type 1 [KO:K04217]
125151342  SSTR2; somatostatin receptor type 2 [KO:K04218]
125154729  SSTR5; somatostatin receptor type 5 [KO:K04221]
125149574  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
125149693  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
125153584  FFAR2; free fatty acid receptor 2 [KO:K04328]
125153585  free fatty acid receptor 2-like [KO:K04328]
125174608  SUCNR1; succinate receptor 1 [KO:K10042]
125173702  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
125160457  OXTR; oxytocin receptor [KO:K04229]
125175551  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
125160707  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
125171553  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
125157897  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
125160918  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
125170902  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
125162135  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
125167442  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
125174584  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
125171196  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
125153013  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
125156381  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
125154541  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
125165890  adenylate cyclase type 10-like isoform X1 [KO:K11265] [EC:4.6.1.1]
125155486  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
125163944  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
125157842  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
125162267  CNGA3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
125176223  CNGA4; cyclic nucleotide-gated cation channel alpha-4 isoform X1 [KO:K04951]
125152543  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
125156594  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
125153015  CALM3; calmodulin-3 [KO:K02183]
125168195  CALM1; calmodulin-1 [KO:K02183]
125168883  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
125162422  CALM2; calmodulin-2 [KO:K02183]
125170921  calmodulin-like [KO:K02183]
125174053  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
125171182  calmodulin-like protein 3 [KO:K02183]
125160440  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
125147418  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
125163373  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
125171549  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha [KO:K04515] [EC:2.7.11.17]
125161805  CAMK4; calcium/calmodulin-dependent protein kinase type IV isoform X1 [KO:K05869] [EC:2.7.11.17]
125166112  BVES; blood vessel epicardial substance [KO:K21108]
125175646  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
125165881  POPDC3; popeye domain-containing protein 3 [KO:K26207]
125155364  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
125159733  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
125168463  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
125173035  ABCC4; ATP-binding cassette sub-family C member 4 isoform X1 [KO:K05673]
125169634  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
125172826  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
125152929  RRAS; ras-related protein R-Ras [KO:K07829]
125176071  RRAS2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
125151242  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
125174683  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
125147489  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
125167460  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
125148372  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
125164491  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
125172327  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
125169828  RAP1B; ras-related protein Rap-1b [KO:K07836]
125174832  TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
125155191  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
125150066  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
125172425  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
125154068  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
125170706  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
125151943  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
125176605  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
125169827  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
125151867  RHOA; transforming protein RhoA [KO:K04513]
125166191  AFDN; afadin isoform X1 [KO:K05702]
125174838  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
125175184  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125172980  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125161995  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
125172124  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
125150373  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
125167750  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125152911  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
125155304  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
125152888  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
125152491  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
125167652  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
125149335  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
125154521  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
125149069  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
125160305  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
125172461  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
125158367  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
125161644  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
125147138  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
125149178  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
125173452  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
125160384  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
125146741  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
125148303  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
125155795  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
125150367  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
125161255  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
125154001  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
125170911  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
125146904  BDNF; LOW QUALITY PROTEIN: brain-derived neurotrophic factor [KO:K04355]
125168871  FOS; protein c-Fos [KO:K04379]
125173215  JUN; transcription factor Jun [KO:K04448]
125160684  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
125170887  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
125150324  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
125164331  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
125168989  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
125163593  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
125176511  RELA; transcription factor p65 [KO:K04735]
125152217  SOX9; transcription factor SOX-9 [KO:K18435]
125160766  AMH; muellerian-inhibiting factor [KO:K04665]
125170324  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
125151474  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
125159194  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
125148866  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
125158892  F2R; proteinase-activated receptor 1 [KO:K03914]
125176067  BAD; bcl2-associated agonist of cell death [KO:K02158]
125152692  LIPE; LOW QUALITY PROTEIN: hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
125148757  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
125158293  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
125169821  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
125161739  MYL9; myosin regulatory light polypeptide 9 isoform X1 [KO:K12755]
125153309  TNNI3; troponin I, cardiac muscle isoform X1 [KO:K12044]
125165485  PLN; cardiac phospholamban [KO:K05852]
125151497  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
125154061  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
125149276  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
125147556  RYR2; ryanodine receptor 2 [KO:K04962]
125150105  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
125154717  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
125169451  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
125151585  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
125153701  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
125150159  GRIN3A; glutamate receptor ionotropic, NMDA 3A isoform X1 [KO:K05213]
125159696  GRIN3B; glutamate receptor ionotropic, NMDA 3B isoform X1 [KO:K05214]
125166575  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
125163820  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
125157737  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
125177275  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
125160811  CFTR; cystic fibrosis transmembrane conductance regulator isoform X1 [KO:K05031] [EC:5.6.1.6]
125153682  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
125155526  sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
125155609  ATP1A4; sodium/potassium-transporting ATPase subunit alpha-4 isoform X1 [KO:K01539] [EC:7.2.2.13]
125172328  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 isoform X1 [KO:K01539] [EC:7.2.2.13]
125151406  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
125175119  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
125154991  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
125157437  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
125176144  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X1 [KO:K01538]
125173276  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
125149700  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
125150942  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
125159311  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
125169923  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
125155174  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
125170417  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
125160941  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
125157244  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
125155193  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
125170162  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform X1 [KO:K19021] [EC:3.1.4.17]
125176061  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform X1 [KO:K13296] [EC:3.1.4.17]
125160711  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
125163457  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
125172520  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
125150158  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
125166038  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
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Related
pathway
pviv00071  Fatty acid degradation
pviv04015  Rap1 signaling pathway
pviv04020  Calcium signaling pathway
pviv04151  PI3K-Akt signaling pathway
pviv04210  Apoptosis
pviv04260  Cardiac muscle contraction
pviv04340  Hedgehog signaling pathway
pviv04720  Long-term potentiation
pviv04740  Olfactory transduction
pviv04972  Pancreatic secretion
pviv04976  Bile secretion
KO pathway
ko04024   
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