KEGG   PATHWAY: rro04024
Entry
rro04024                    Pathway                                
Name
cAMP signaling pathway - Rhinopithecus roxellana (golden snub-nosed monkey)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
rro04024  cAMP signaling pathway
rro04024

Other DBs
GO: 0019933
Organism
Rhinopithecus roxellana (golden snub-nosed monkey) [GN:rro]
Gene
104653509  POPDC3; popeye domain-containing protein 3 [KO:K26207]
104653510  BVES; blood vessel epicardial substance [KO:K21108]
104653552  SST; somatostatin [KO:K05237]
104653554  CALML6; calmodulin-like protein 6 isoform X2 [KO:K02183]
104653804  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
104654172  PLN; cardiac phospholamban [KO:K05852]
104654186  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
104654834  RAPGEF3; rap guanine nucleotide exchange factor 3 [KO:K08014]
104654871  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
104654910  EDN2; endothelin-2 [KO:K16367]
104654979  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
104655383  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
104655463  ROCK1; LOW QUALITY PROTEIN: rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.1]
104655475  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
104655485  F2R; proteinase-activated receptor 1 [KO:K03914]
104655987  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
104656623  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
104656871  [KO:K02183]
104657055  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
104657166  GHSR; LOW QUALITY PROTEIN: growth hormone secretagogue receptor type 1 [KO:K04284]
104657322  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
104657358  EDN1; endothelin-1 [KO:K16366]
104657551  NPPA; natriuretic peptides A [KO:K12334]
104657622  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
104657722  DRD5; D(1B) dopamine receptor [KO:K05840]
104657770  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
104657853  VIP; VIP peptides isoform X1 [KO:K05264]
104658112  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
104658457  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
104658538  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
104658627  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
104658672  RAP1B; ras-related protein Rap-1b [KO:K07836]
104658678  LIPE; hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
104658805  ABCC4; multidrug resistance-associated protein 4 isoform X1 [KO:K05673]
104658863  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
104658932  RAP1A; ras-related protein Rap-1A [KO:K04353]
104659017  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
104659193  ADRB1; beta-1 adrenergic receptor [KO:K04141]
104659677  GIP; gastric inhibitory polypeptide [KO:K05258]
104659700  BRAF; serine/threonine-protein kinase B-raf isoform X2 [KO:K04365] [EC:2.7.11.1]
104660033  SSTR2; somatostatin receptor type 2 [KO:K04218]
104660209  EDNRA; endothelin-1 receptor isoform X1 [KO:K04197]
104660405  ATP1A4; sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
104660406  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
104660878  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
104661051  [KO:K04345] [EC:2.7.11.11]
104661187  ATP2B3; plasma membrane calcium-transporting ATPase 3 [KO:K05850] [EC:7.2.2.10]
104661276  GCG; glucagon [KO:K05259]
104661379  SSTR1; somatostatin receptor type 1 [KO:K04217]
104661476  CNGA3; cyclic nucleotide-gated cation channel alpha-3 isoform X1 [KO:K04950]
104661660  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
104661816  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X5 [KO:K04853]
104661868  CACNA1S; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
104661942  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
104662055  [KO:K02183]
104662061  PRKACG; cAMP-dependent protein kinase catalytic subunit gamma isoform X1 [KO:K04345] [EC:2.7.11.11]
104662124  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
104662315  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
104662549  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
104662575  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
104662590  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
104662674  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
104662841  GPHA2; glycoprotein hormone alpha-2 isoform X1 [KO:K25483]
104663050  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
104663087  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
104663105  ATP1B4; protein ATP1B4 [KO:K01540]
104663129  GLI3; transcriptional activator GLI3 [KO:K06230]
104663170  CALM2; calmodulin-2 [KO:K02183]
104663235  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
104663334  TSHR; thyrotropin receptor [KO:K04249]
104663511  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
104663522  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
104663741  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
104663797  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
104663799  [KO:K04632]
104663806  EDN3; endothelin-3 isoform X3 [KO:K05227]
104664064  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
104664220  FSHB; follitropin subunit beta [KO:K05250]
104664278  JUN; transcription factor AP-1 [KO:K04448]
104664316  PAK1; serine/threonine-protein kinase PAK 1 isoform X5 [KO:K04409] [EC:2.7.11.1]
104664652  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
104664815  RELA; transcription factor p65 [KO:K04735]
104664823  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
104664834  CALML5; calmodulin-like protein 5 [KO:K02183]
104664835  CALML3; calmodulin-like protein 3 [KO:K02183]
104664927  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
104665061  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
104665356  VAV1; proto-oncogene vav [KO:K05730]
104665486  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
104665487  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
104665560  [KO:K01538]
104665823  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
104665933  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
104666130  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X2 [KO:K05860] [EC:3.1.4.11]
104666170  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
104666279  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
104666306  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
104666307  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
104666484  NPY; pro-neuropeptide Y [KO:K05232]
104666536  LHB; lutropin subunit beta [KO:K08521]
104666582  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
104666985  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
104667101  FFAR2; free fatty acid receptor 2 [KO:K04328]
104667102  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
104667117  FXYD1; phospholemman isoform X1 [KO:K13360]
104667141  GHRL; appetite-regulating hormone [KO:K05254]
104667204  RRAS; ras-related protein R-Ras isoform X1 [KO:K07829]
104667372  RHOA; transforming protein RhoA [KO:K04513]
104667476  OXTR; oxytocin receptor [KO:K04229]
104667722  GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1 [KO:K05209]
104667797  NFATC1; LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 1 [KO:K04446]
104668007  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
104668142  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
104668156  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
104668385  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
104668443  CRHR2; LOW QUALITY PROTEIN: corticotropin-releasing factor receptor 2 [KO:K04579]
104668466  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
104668603  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
104668794  CRH; corticoliberin [KO:K05256]
104668941  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
104668945  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
104668946  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
104668956  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
104668974  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
104669072  TSHB; thyrotropin subunit beta [KO:K05251]
104669119  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
104669170  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
104669189  SUCNR1; LOW QUALITY PROTEIN: succinate receptor 1 [KO:K10042]
104669226  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
104669771  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
104669784  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
104669984  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
104669989  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104670410  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
104670476  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X4 [KO:K13293] [EC:3.1.4.53]
104670544  CALM1; calmodulin-1 [KO:K02183]
104670605  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
104670760  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
104670807  GRIN3A; glutamate receptor ionotropic, NMDA 3A isoform X1 [KO:K05213]
104671126  BDNF; brain-derived neurotrophic factor isoform X1 [KO:K04355]
104671146  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
104671165  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
104671354  VAV3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
104671445  AMH; muellerian-inhibiting factor [KO:K04665]
104671458  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
104671466  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
104671763  VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
104671837  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
104672204  NPY1R; neuropeptide Y receptor type 1 isoform X1 [KO:K04204]
104672288  ADCY9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
104672289  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
104672388  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
104672444  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
104672500  ADORA2A; adenosine receptor A2a [KO:K04266]
104672569  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
104672686  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
104673041  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104673141  BAD; bcl2-associated agonist of cell death [KO:K02158]
104673260  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
104673281  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
104673299  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
104673307  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
104673406  CALM3; calmodulin-3 [KO:K02183]
104673433  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
104673512  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X5 [KO:K04351]
104673925  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
104674060  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 isoform X1 [KO:K01540]
104674083  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
104674106  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
104674211  [KO:K02183]
104674286  CNGB3; cyclic nucleotide-gated cation channel beta-3 isoform X1 [KO:K04953]
104674493  ADORA1; adenosine receptor A1 isoform X2 [KO:K04265]
104674615  OXT; oxytocin-neurophysin 1 [KO:K05243]
104674758  TNNI3; troponin I, cardiac muscle [KO:K12044]
104674813  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X3 [KO:K05853] [EC:7.2.2.10]
104674855  PPP1R1B; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
104675136  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
104675191  ROCK2; rho-associated protein kinase 2 isoform X5 [KO:K17388] [EC:2.7.11.1]
104675620  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
104675683  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
104675732  SLC9A1; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
104675773  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
104675861  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
104676121  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
104676194  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
104676623  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
104676766  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
104676897  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
104677250  ATP2A3; LOW QUALITY PROTEIN: sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [KO:K05853] [EC:7.2.2.10]
104677371  DRD2; D(2) dopamine receptor isoform X1 [KO:K04145]
104677489  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
104677590  FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos [KO:K04379]
104677657  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
104677878  POMC; pro-opiomelanocortin [KO:K05228]
104678069  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
104678288  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
104678447  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
104678498  AFDN; LOW QUALITY PROTEIN: afadin [KO:K05702]
104678969  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
104679189  RYR2; ryanodine receptor 2 isoform X1 [KO:K04962]
104679802  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
104679824  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
104679865  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
104680220  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
104680548  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
104680613  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
104680672  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
104680741  [KO:K02183]
104680758  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
104680760  ADRB2; beta-2 adrenergic receptor [KO:K04142]
104681150  MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
104681285  ACOX1; LOW QUALITY PROTEIN: peroxisomal acyl-coenzyme A oxidase 1 [KO:K00232] [EC:1.3.3.6]
104681333  GRIN2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C [KO:K05211]
104681494  SSTR5; somatostatin receptor type 5 [KO:K04221]
104681604  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
104681605  CGA; glycoprotein hormones alpha chain [KO:K08522]
104681826  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
104681895  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
104681930  DRD1; D(1A) dopamine receptor [KO:K04144]
104681940  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
104681946  RRAS2; ras-related protein R-Ras2 [KO:K07830]
104682143  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
104682362  GLI1; zinc finger protein GLI1 [KO:K16797]
104682394  CRHR1; corticotropin-releasing factor receptor 1 [KO:K04578]
104682459  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [KO:K13293] [EC:3.1.4.53]
104682502  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
104682625  CFTR; cystic fibrosis transmembrane conductance regulator isoform X1 [KO:K05031] [EC:5.6.1.6]
104682715  SOX9; transcription factor SOX-9 [KO:K18435]
104682905  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
115891994  [KO:K04579]
115893905  [KO:K04456] [EC:2.7.11.1]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
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Cell Calcium 55:385-393 (2014)
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Biochemistry (Mosc) 76:981-98 (2011)
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J Am Coll Cardiol 54:1747-62 (2009)
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Related
pathway
rro00071  Fatty acid degradation
rro04015  Rap1 signaling pathway
rro04020  Calcium signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04210  Apoptosis
rro04260  Cardiac muscle contraction
rro04340  Hedgehog signaling pathway
rro04720  Long-term potentiation
rro04740  Olfactory transduction
rro04972  Pancreatic secretion
rro04976  Bile secretion
KO pathway
ko04024   

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