KEGG    Network variation - Salmonella
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ENTRYnt06181
NameSalmonella
CategoryDisease view; Bacterial infection
Pathwayhsa05132 Salmonella infection
DiseaseH00111 Typhoid fever
Display drug-target relation   disease type
MAPK signaling
N01119      (RAC1,CDC42)PAK1RAFMEKERK
N01120    SptP(RAC1,CDC42)
N01134    SopBCDC42
N01121            SpvCERK
 
WNT signaling
N00056    WNT(FZD+LRP5/6)(DVL+FRAT)(GSK3B+AXIN+APC)CTNNB1TCF/LEF(MYC,CCND1)
N01124          AvrACTNNB1TCF/LEFMYC
 
TNF signaling
N00446    TNFTNFRSF1A(RIPK1+TRADD+TRAF2..(TAK1+TAB1/2)MKK4/7JNKAP1
N01125          AvrAMAP2K7
N00151    TNFTNFRSF1A(RIPK1+TRADD+TRAF2..(TAB1/2/3+TAK1)IKKNFKBIANFKB
N01114    SseK3TNFRSF1A
N01113      SseK1(RIPK1+TRADD+TRAF2..
N01117          GogBSKP1NFKBIA
N01116            SseLNFKBIA
N01123            AvrANFKBIA
N01118          SpvDXPO2(KPNA1+KPNA3)NFKB
N01122              PipARELA
 
NLR signaling
N00940        (NOD1,NOD2)RIPK2IKKNFKBIANFKB
N01112    SopE/E2CDC42NOD1RIPK2IKKNFKBIANFKB
N00742      (NLRP3+PYCARD)CASP1(IL1B,IL18,IL33)
N01127    SopERAC1CASP1(IL1B,IL18)
N01126      SipBCASP1(IL1B,IL18)
 
Cytoskeletal regulation
N01072    FN1(ITGA+ITGB)PTK2ARHGEF28RHOA
N01130          SopBRHOAROCK2MLC
N01131          SopE/E2RHOAROCK2FHOD1
N01068    FN1(ITGA+ITGB)(SRC,PTK2)(PXN,CRK+BCAR1)(DOCK1+ELMO1)RAC
N01128            SopERAC1(WASF+ABI1+HSPC300..ARP2/3(ACTB,ACTG1)
N00951    FN1(ITGA+ITGB)RHOG(DOCK1+ELMO)RAC
N01133    SopBARHGEF26RHOGELMO
N01132      SopE/E2RHOGELMO
N01066          ARNOARF6ARF1(WASF+ABI1+HSPC300..ARP2/3(ACTB,ACTG1)
N01129    SopB(PIK3CA/B/G/D,PIK3..PIP3ARNOARF6ARF1(WASF+ABI1+HSPC300..ARP2/3(ACTB,ACTG1)
N01304      (ANXA2+S100A10)=AHNAK=(ACTB,ACTG1)
N01305    (SopB,SopE)(ANXA2+S100A10)=AHNAK=(ACTB,ACTG1)
 
Membrane trafficking
N01302    (RABGEF1+RABEP1)RAB5(PIK3C3+PIK3R4)PI3PEEA1
N01303    SopBRAB5PIK3C3PI3P
N01295      RAB7=RILP=OSBPL1A=(DYNC+DYNL+DCTN+AC..=(TUBA+TUBB)
N01296    SopD2RAB7
N01297    BORCS=ARL8=PLEKHM2=(KIF5+KLC)=(TUBA+TUBB)
N01298      SifAPLEKHM2=(KIF5+KLC)=(TUBA+TUBB)
N01299        PipB2(KIF5+KLC)=(TUBA+TUBB)
N01300    ARL8B=PLEKHM1=RAB7=HOPS
N01301    SifA=PLEKHM1=RAB7=HOPS