Entry
Name
Spliceosome - Helianthus annuus (common sunflower)
Description
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.
Class
Genetic Information Processing; Transcription
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Helianthus annuus (common sunflower) [GN:
han ]
Gene
110885822 small nuclear ribonucleoprotein-associated protein B' [KO:K11086 ]
110872447 small nuclear ribonucleoprotein-associated protein B'-like [KO:K11086 ]
110868228 probable small nuclear ribonucleoprotein F isoform X1 [KO:K11098 ]
118481934 transcription initiation factor TFIID subunit 15b-like [KO:K13098 ]
110910660 survival of motor neuron-related-splicing factor 30 isoform X2 [KO:K12839 ]
110944008 DNA-damage-repair/toleration protein DRT111, chloroplastic [KO:K12840 ]
118489201 U4/U6 small nuclear ribonucleoprotein PRP4-like protein [KO:K12662 ]
110894569 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein [KO:K12846 ]
110886695 110 kDa U5 small nuclear ribonucleoprotein component CLO [KO:K12852 ]
110877876 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
110885481 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
110929044 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
110941405 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
110929117 LOW QUALITY PROTEIN: heat shock cognate 70 kDa protein [KO:K03283 ]
110939778 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
110910921 calponin homology domain-containing protein DDB_G0272472 isoform X1 [KO:K12875 ]
110912098 apoptotic chromatin condensation inducer in the nucleus isoform X1 [KO:K12875 ]
110903685 apoptotic chromatin condensation inducer in the nucleus [KO:K12875 ]
110877989 serine/arginine-rich splicing factor SR34A isoform X1 [KO:K12890 ]
110925763 serine/arginine-rich splicing factor RSZ22 isoform X1 [KO:K12896 ]
110904980 serine/arginine-rich splicing factor RS2Z33 isoform X1 [KO:K12896 ]
110898743 serine/arginine-rich SC35-like splicing factor SCL30A isoform X2 [KO:K12900 ]
110890876 serine/arginine-rich SC35-like splicing factor SCL30A [KO:K12900 ]
110876868 serine/arginine-rich SC35-like splicing factor SCL30A [KO:K12900 ]
110868835 serine/arginine-rich SC35-like splicing factor SCL30 isoform X1 [KO:K12900 ]
110908702 serine/arginine-rich SC35-like splicing factor SCL30A [KO:K12900 ]
110878737 serine/arginine-rich SC35-like splicing factor SCL28 isoform X1 [KO:K12900 ]
Reference
Authors
Wahl MC, Will CL, Luhrmann R
Title
The spliceosome: design principles of a dynamic RNP machine.
Journal
Reference
Authors
Morris DP, Greenleaf AL
Title
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.
Journal
Reference
Authors
Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW
Title
Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.
Journal
Reference
Authors
Ritchie DB, Schellenberg MJ, MacMillan AM
Title
Spliceosome structure: piece by piece.
Journal
KO pathway
LinkDB
All DBs