KEGG   PATHWAY: rfq04024
Entry
rfq04024                    Pathway                                
Name
cAMP signaling pathway - Rhinolophus ferrumequinum (greater horseshoe bat)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
rfq04024  cAMP signaling pathway
rfq04024

Other DBs
GO: 0019933
Organism
Rhinolophus ferrumequinum (greater horseshoe bat) [GN:rfq]
Gene
117011750  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
117011752  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
117011863  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
117011995  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
117012053  CRHR2; corticotropin-releasing factor receptor 2 isoform X1 [KO:K04579]
117012276  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
117012305  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
117012353  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
117012370  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
117012380  NPY; pro-neuropeptide Y [KO:K05232]
117012438  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
117012484  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
117012638  SSTR2; somatostatin receptor type 2 [KO:K04218]
117012711  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
117012823  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
117012950  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
117012976  PPP1R1B; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
117013010  ACOX1; LOW QUALITY PROTEIN: peroxisomal acyl-coenzyme A oxidase 1 [KO:K00232] [EC:1.3.3.6]
117013141  SOX9; transcription factor SOX-9 [KO:K18435]
117013297  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
117013437  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
117013546  [KO:K02183]
117013723  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
117013780  GRIN2C; glutamate receptor ionotropic, NMDA 2C isoform X1 [KO:K05211]
117013784  CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
117013903  GIP; gastric inhibitory polypeptide [KO:K05258]
117014324  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
117014353  ADCY10; LOW QUALITY PROTEIN: adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
117014362  [KO:K01539] [EC:7.2.2.13]
117014645  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
117014781  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
117014800  VAV3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
117014998  TSHB; thyrotropin subunit beta [KO:K05251]
117015109  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
117015117  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
117015251  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
117015413  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
117015436  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
117015628  EDN3; endothelin-3 [KO:K05227]
117015642  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
117015682  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
117015705  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
117015708  [KO:K04632]
117016056  OXT; oxytocin-neurophysin 1 [KO:K05243]
117016447  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
117016453  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
117016476  DRD1; D(1A) dopamine receptor [KO:K04144]
117016597  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
117016634  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
117016683  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
117016786  ADRB2; beta-2 adrenergic receptor [KO:K04142]
117016949  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
117017227  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
117017296  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
117017478  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
117017501  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
117017773  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
117017884  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
117017888  ADORA2A; adenosine receptor A2a [KO:K04266]
117017948  VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
117018062  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
117018063  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
117018247  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
117018340  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
117018458  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
117018496  RYR2; ryanodine receptor 2 isoform X1 [KO:K04962]
117018518  ADORA1; adenosine receptor A1 isoform X1 [KO:K04265]
117018578  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S isoform X1 [KO:K04857]
117019071  AFDN; afadin isoform X1 [KO:K05702]
117019182  [KO:K02183]
117019237  [KO:K02183]
117019455  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
117019474  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
117019508  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
117019640  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
117019701  SSTR5; somatostatin receptor type 5 [KO:K04221]
117019989  [KO:K18438] [EC:3.1.4.17 3.1.4.35]
117020159  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 [KO:K04615]
117020216  VIP; VIP peptides [KO:K05264]
117020315  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
117020360  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
117020427  CGA; glycoprotein hormones alpha chain [KO:K08522]
117020442  [KO:K11265] [EC:4.6.1.1]
117020477  PLN; cardiac phospholamban [KO:K05852]
117020710  [KO:K05264]
117020711  [KO:K05264]
117020712  [KO:K05264]
117020844  BVES; blood vessel epicardial substance [KO:K21108]
117020904  POPDC3; popeye domain-containing protein 3 [KO:K26207]
117021587  ABCC4; multidrug resistance-associated protein 4 [KO:K05673]
117022138  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
117022220  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
117022277  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
117022439  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
117022459  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
117022660  DRD5; D(1B) dopamine receptor [KO:K05840]
117022829  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
117022834  TSHR; thyrotropin receptor [KO:K04249]
117022841  CALM1; calmodulin-1 [KO:K02183]
117022867  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
117022959  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
117022968  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
117023033  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
117023064  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
117023560  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
117024116  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
117024158  FOS; proto-oncogene c-Fos [KO:K04379]
117024169  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
117024182  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
117024228  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
117024505  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
117024531  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
117024996  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
117025090  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
117025288  F2R; proteinase-activated receptor 1 [KO:K03914]
117025350  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
117025697  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
117025801  GCG; glucagon isoform X1 [KO:K05259]
117025886  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
117026182  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
117026302  [KO:K04440] [EC:2.7.11.24]
117026472  CALML6; calmodulin-like protein 6 [KO:K02183]
117026579  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
117026585  EDN1; endothelin-1 [KO:K16366]
117026708  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
117027001  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
117027160  [KO:K02649]
117027173  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
117027175  JUN; transcription factor AP-1 [KO:K04448]
117027278  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
117027369  EDN2; endothelin-2 [KO:K16367]
117027443  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117027591  PTGER3; prostaglandin E2 receptor EP3 subtype [KO:K04260]
117027677  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
117027714  NPPA; natriuretic peptides A [KO:K12334]
117028042  GLI1; zinc finger protein GLI1 [KO:K16797]
117028151  [KO:K04260]
117028155  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
117028303  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
117028313  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
117028527  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
117028533  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
117028675  RAP1B; ras-related protein Rap-1b [KO:K07836]
117028710  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
117029121  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
117029241  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
117029264  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
117029473  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
117029758  BDNF; LOW QUALITY PROTEIN: brain-derived neurotrophic factor [KO:K04355]
117029941  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
117030046  RRAS2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
117030073  BAD; bcl2-associated agonist of cell death [KO:K02158]
117030205  FSHB; follitropin subunit beta [KO:K05250]
117030253  [KO:K01538]
117030472  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
117030559  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
117030679  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
117030742  RELA; transcription factor p65 isoform X1 [KO:K04735]
117030845  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
117030926  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
117031018  GPHA2; LOW QUALITY PROTEIN: glycoprotein hormone alpha-2 [KO:K25483]
117031053  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
117031197  SUCNR1; succinate receptor 1 isoform X1 [KO:K10042]
117031245  PAK1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
117031331  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
117031342  DRD2; D(2) dopamine receptor isoform X1 [KO:K04145]
117031476  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
117031882  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
117031907  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
117032144  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
117032281  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
117032504  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
117032669  CNGA3; cyclic nucleotide-gated cation channel alpha-3 isoform X1 [KO:K04950]
117032856  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
117032986  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
117033010  CALM2; calmodulin-2 [KO:K02183]
117033055  POMC; pro-opiomelanocortin [KO:K05228]
117033138  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
117033154  FSHR; LOW QUALITY PROTEIN: follicle-stimulating hormone receptor [KO:K04247]
117033436  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
117033942  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
117033982  CRH; corticoliberin [KO:K05256]
117034016  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
117034330  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
117034378  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
117034399  GIPR; gastric inhibitory polypeptide receptor [KO:K04580]
117034458  RRAS; ras-related protein R-Ras [KO:K07829]
117034738  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
117034828  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
117034856  CALM3; calmodulin-3 [KO:K02183]
117034883  TNNI3; troponin I, cardiac muscle isoform X1 [KO:K12044]
117034964  [KO:K04328]
117034993  FXYD1; phospholemman [KO:K13360]
117035060  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
117035064  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
117035083  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
117035485  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
117035752  ADRB1; beta-1 adrenergic receptor [KO:K04141]
117035828  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
117035933  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
117035942  ATP1B4; protein ATP1B4 [KO:K01540]
117036083  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
117036555  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
117036663  RHOA; transforming protein RhoA [KO:K04513]
117036785  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
117036905  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
117036932  GHRL; appetite-regulating hormone [KO:K05254]
117036998  OXTR; oxytocin receptor isoform X1 [KO:K04229]
117037029  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
117037170  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
117037259  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
117037433  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
117037445  SST; somatostatin [KO:K05237]
117037567  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
117037633  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
117037652  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
117037654  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
117037765  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
117037860  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
117037869  AMH; muellerian-inhibiting factor [KO:K04665]
117037901  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
117037911  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
117038041  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
117038075  CAMK2D; LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta [KO:K04515] [EC:2.7.11.17]
117038242  EDNRA; endothelin-1 receptor [KO:K04197]
117038261  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
117038345  VAV1; proto-oncogene vav [KO:K05730]
117038678  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
  Title
cAMP and Ca signaling in secretory epithelia: Crosstalk and synergism.
  Journal
Cell Calcium 55:385-393 (2014)
DOI:10.1016/j.ceca.2014.01.006
Reference
  Authors
Shirshev SV
  Title
Role of Epac proteins in mechanisms of cAMP-dependent immunoregulation.
  Journal
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Related
pathway
rfq00071  Fatty acid degradation
rfq04015  Rap1 signaling pathway
rfq04020  Calcium signaling pathway
rfq04151  PI3K-Akt signaling pathway
rfq04210  Apoptosis
rfq04260  Cardiac muscle contraction
rfq04340  Hedgehog signaling pathway
rfq04720  Long-term potentiation
rfq04740  Olfactory transduction
rfq04972  Pancreatic secretion
rfq04976  Bile secretion
KO pathway
ko04024   

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