KEGG   PATHWAY: sluc05132
Entry
sluc05132                   Pathway                                
Name
Salmonella infection - Sander lucioperca (pikeperch)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
sluc05132  Salmonella infection
sluc05132

Disease
H00111  Typhoid fever
Organism
Sander lucioperca (pikeperch) [GN:sluc]
Gene
116034107  myl9b; myosin regulatory light polypeptide 9b [KO:K12755]
116034155  [KO:K08847] [EC:2.7.11.1]
116034295  lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
116034351  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
116034528  myl2a; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
116034969  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
116034978  [KO:K07375]
116035011  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
116035276  ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
116035362  rab7a; ras-related protein Rab-7a [KO:K07897]
116035524  [KO:K05755]
116035556  exoc5; exocyst complex component 5 [KO:K19984]
116035578  fosaa; proto-oncogene c-Fos isoform X1 [KO:K04379]
116035601  arf6b; ADP-ribosylation factor 6b [KO:K07941]
116035670  [KO:K18584]
116035672  myo6b; myosin VIb isoform X1 [KO:K10358]
116035790  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
116035910  [KO:K03156]
116035995  si:dkey-13a21.4; ras-related protein rab7 [KO:K07897]
116036000  rab5ab; ras-related protein Rab-5A [KO:K07887]
116036053  rela; transcription factor p65 isoform X1 [KO:K04735]
116036261  arl8bb; ADP-ribosylation factor-like 8Bb [KO:K07955]
116036271  wasla; WASP like actin nucleation promoting factor a isoform X2 [KO:K23612]
116036332  [KO:K08849] [EC:2.7.11.1]
116036419  rhogb; rho-related GTP-binding protein RhoG [KO:K07863]
116036562  [KO:K02187] [EC:3.4.22.56]
116036563  [KO:K02187] [EC:3.4.22.56]
116036564  [KO:K02187] [EC:3.4.22.56]
116036711  klc1a; kinesin light chain 1 isoform X1 [KO:K10407]
116036736  [KO:K23934]
116037274  [KO:K10415]
116037337  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
116037720  [KO:K20282]
116037846  wasf3b; wiskott-Aldrich syndrome protein family member 3b [KO:K06083]
116037895  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
116037927  kpna1; importin subunit alpha-5 [KO:K23940]
116038100  [KO:K00922] [EC:2.7.1.153]
116038159  exoc2; exocyst complex component 2 [KO:K17637]
116038419  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
116038421  [KO:K04513]
116038429  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
116038435  irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
116038475  hsp90b1; endoplasmin [KO:K09487]
116038647  mapk12a; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
116038742  [KO:K02833]
116038743  [KO:K17092]
116038947  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
116039338  klc1b; kinesin light chain 1b isoform X1 [KO:K10407]
116040032  tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
116040211  [KO:K08847] [EC:2.7.11.1]
116040316  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
116040322  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
116040469  [KO:K10030]
116040472  rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
116040483  [KO:K10428]
116040543  [KO:K10030]
116040544  [KO:K10030]
116040651  plekhm2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
116040658  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
116040732  si:ch211-112c15.8; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
116040750  mapk14a; mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
116040793  zgc:171775; STKc_p38 domain-containing protein isoform X1 [KO:K04441] [EC:2.7.11.24]
116040854  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
116040928  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
116040932  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
116040995  si:rp71-17i16.5; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
116041080  kif5aa; kinesin family member 5Aa isoform X1 [KO:K10396] [EC:5.6.1.3]
116041206  [KO:K23938]
116041404  june; junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
116041411  [KO:K03156]
116041524  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
116041618  [KO:K04513]
116041680  si:dkey-197j19.6; neural Wiskott-Aldrich syndrome protein [KO:K23612]
116041682  [KO:K07897]
116041693  cse1l; exportin-2 [KO:K18423]
116041786  [KO:K04490]
116041843  actr1; actin related protein 1, centractin [KO:K16575]
116041859  [KO:K04397] [EC:3.4.22.60]
116041861  [KO:K04397] [EC:3.4.22.60]
116041874  [KO:K12753]
116041969  [KO:K04734]
116042114  [KO:K10169]
116042282  [KO:K04648]
116042555  [KO:K23937]
116042632  cyth4b; cytohesin 4b isoform X1 [KO:K18441]
116042635  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X3 [KO:K04431] [EC:2.7.12.2]
116042675  actb1; actin, cytoplasmic 1 [KO:K05692]
116042686  pkn1a; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
116042689  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
116042795  dnm2b; dynamin-2 isoform X1 [KO:K23484]
116042806  [KO:K07375]
116042845  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
116042922  arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
116043294  txn; thioredoxin [KO:K03671]
116043323  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
116043440  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
116043598  tuba5; tubulin alpha 5 [KO:K07374]
116043633  [KO:K04393]
116043720  [KO:K07374]
116043889  [KO:K05403]
116043988  [KO:K05754]
116044233  [KO:K18441]
116044236  [KO:K04392]
116044451  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
116044500  [KO:K18584]
116044549  [KO:K07374]
116044552  [KO:K07374]
116044657  [KO:K07899]
116044835  [KO:K07374]
116044836  [KO:K07374]
116044854  [KO:K10420]
116044913  [KO:K10396] [EC:5.6.1.3]
116045089  zgc:86896; actin-related protein 2/3 complex subunit 1A-A [KO:K05757]
116045235  fadd; protein FADD [KO:K02373]
116045254  myl12.1; myosin, light chain 12, genome duplicate 1 [KO:K12757]
116045313  vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
116045331  myca; transcriptional regulator Myc-A isoform X1 [KO:K04377]
116045405  myo6a; myosin VIa isoform X1 [KO:K10358]
116045451  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
116045453  [KO:K07374]
116045685  [KO:K10419]
116045695  [KO:K08847] [EC:2.7.11.1]
116045703  [KO:K04448]
116045897  kpna3; importin subunit alpha-4 [KO:K23583]
116045953  myl12.2; myosin, light chain 12, genome duplicate 2 [KO:K12757]
116045979  arf1; ADP-ribosylation factor 1 [KO:K07937]
116046027  ripk1l; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
116046046  [KO:K07375]
116046065  bcl2b; apoptosis regulator Bcl-2 [KO:K02161]
116046126  [KO:K00922] [EC:2.7.1.153]
116046139  [KO:K08846] [EC:2.7.11.1]
116046186  [KO:K05759]
116046202  [KO:K21954]
116046405  [KO:K00134] [EC:1.2.1.12]
116046410  [KO:K04393]
116046534  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
116046585  [KO:K10420]
116046733  pkn1b; serine/threonine-protein kinase N1b isoform X3 [KO:K06071] [EC:2.7.11.13]
116046752  txn2; thioredoxin, mitochondrial [KO:K03671]
116046816  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
116047007  tlr5a; toll-like receptor 5 isoform X1 [KO:K10168]
116047072  [KO:K07375]
116047234  zgc:101785; annexin A2 isoform X2 [KO:K17092]
116047321  s100a10a; protein S100-A10a [KO:K17274]
116047417  rab9a; ras-related protein Rab-9A [KO:K07899]
116047637  rab5b; ras-related protein Rab-5B [KO:K07888]
116047668  hdr; hematopoietic death receptor isoform X5 [KO:K04722]
116047679  [KO:K01370] [EC:3.4.22.36]
116047779  mych; myelocytomatosis oncogene homolog isoform X1 [KO:K04377]
116047872  [KO:K07374]
116048004  casp10; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
116048122  [KO:K08738]
116048249  [KO:K10414]
116048307  [KO:K13883]
116048486  dynll2a; dynein, light chain, LC8-type 2a [KO:K10418]
116048556  [KO:K10415]
116048576  abi1a; abl interactor 1a isoform X1 [KO:K23649]
116048589  ralaa; v-ral simian leukemia viral oncogene homolog Aa (ras related) [KO:K07834]
116048619  [KO:K10396] [EC:5.6.1.3]
116048711  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
116048882  [KO:K17923]
116048939  [KO:K10396] [EC:5.6.1.3]
116049005  dctn6; dynactin subunit 6 [KO:K10428]
116049085  tlr18; toll-like receptor 18 [KO:K10159]
116049102  dctn3; dynactin subunit 3 [KO:K10425]
116049146  [KO:K06083]
116049156  [KO:K08847] [EC:2.7.11.1]
116049187  [KO:K08847] [EC:2.7.11.1]
116049189  [KO:K08847] [EC:2.7.11.1]
116049191  [KO:K08847] [EC:2.7.11.1]
116049192  [KO:K08847] [EC:2.7.11.1]
116049426  [KO:K07375]
116049555  [KO:K17274]
116049608  si:dkey-283b15.4; cytohesin-2 [KO:K18441]
116049666  m6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
116049698  gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
116049703  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A isoform X3 [KO:K03158]
116049717  cdc42l; cell division cycle 42, like [KO:K04393]
116049744  tubb5; tubulin beta-5 chain [KO:K07375]
116049916  si:ch211-69b7.6; neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
116049979  [KO:K07374]
116050047  [KO:K07374]
116050408  [KO:K03173] [EC:2.3.2.27]
116050528  [KO:K07374]
116050529  [KO:K07374]
116050643  tubb2b; tubulin beta-2b chain [KO:K07375]
116050817  [KO:K13744]
116050840  kpna4; importin subunit alpha-3 [KO:K23583]
116051244  brk1; probable protein BRICK1 [KO:K05752]
116051253  arl8ba; ADP-ribosylation factor-like protein 8B-A [KO:K07955]
116051364  kif5ab; kinesin heavy chain isoform X1 [KO:K10396] [EC:5.6.1.3]
116051368  dctn2; dynactin subunit 2 isoform X1 [KO:K10424]
116051376  nckap1l; nck-associated protein 1-like [KO:K05750]
116051439  rhoca; ras homolog family member Ca isoform X1 [KO:K04513]
116051559  tubb1; tubulin beta-1 chain [KO:K07375]
116051677  myl2b; myosin, light chain 2b, regulatory, cardiac, slow isoform X1 [KO:K10351]
116051764  [KO:K10159]
116052052  cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
116052112  [KO:K10159]
116052182  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
116052391  ahnak; neuroblast differentiation-associated protein AHNAK [KO:K23934]
116052794  dynlrb1; dynein light chain roadblock-type 1 [KO:K10419]
116052977  [KO:K08847] [EC:2.7.11.1]
116052983  [KO:K08847] [EC:2.7.11.1]
116053123  [KO:K04467] [EC:2.7.11.10]
116053180  zgc:109889; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
116053208  klc3; kinesin light chain 3 [KO:K10407]
116053250  ripk3; receptor-interacting serine/threonine-protein kinase 3 isoform X1 [KO:K08847] [EC:2.7.11.1]
116053291  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
116053314  rps3; 40S ribosomal protein S3 [KO:K02985]
116053328  si:ch211-63p21.2; FH1/FH2 domain-containing protein 1 [KO:K23938]
116053372  klc2; kinesin light chain 2 [KO:K10407]
116053379  zgc:101810; actin-related protein 2 [KO:K17260]
116053397  [KO:K10030]
116053408  cxcl19; C-X-C motif chemokine 19 [KO:K10030]
116053441  mapk8a; mitogen-activated protein kinase 8 isoform X6 [KO:K04440] [EC:2.7.11.24]
116053887  tcf7l1b; transcription factor 7-like 1-B isoform X1 [KO:K04490]
116054000  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
116054032  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
116054171  [KO:K04519]
116054211  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
116054251  snx18a; sorting nexin-18a [KO:K17923]
116054285  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
116054456  dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
116054510  podxl; podocalyxin [KO:K06817]
116054767  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
116054782  mapk11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
116054783  [KO:K04441] [EC:2.7.11.24]
116054943  [KO:K08847] [EC:2.7.11.1]
116055058  [KO:K04398] [EC:3.4.22.61]
116055079  casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
116055190  pfn2; profilin-2 isoform X1 [KO:K05759]
116055193  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
116055515  cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
116055603  vps16; vacuolar protein sorting-associated protein 16 homolog isoform X1 [KO:K20180]
116055911  tcf7; transcription factor 7 isoform X1 [KO:K02620]
116055913  skp1; S-phase kinase-associated protein 1 [KO:K03094]
116056292  ptprc; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
116056317  [KO:K17092]
116056492  [KO:K16060]
116056504  tubb6; tubulin beta-5 chain isoform X1 [KO:K07375]
116056540  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
116056614  [KO:K05692]
116056692  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 isoform X1 [KO:K10417]
116057008  cyfip1; cytoplasmic FMR1-interacting protein 1 homolog [KO:K05749]
116057349  vps39; vam6/Vps39-like protein isoform X1 [KO:K20183]
116057578  dctn1b; dynactin subunit 1 isoform X1 [KO:K04648]
116057643  dync1h1; cytoplasmic dynein 1 heavy chain 1 isoform X1 [KO:K10413]
116057709  [KO:K04721]
116057840  [KO:K18584]
116057842  [KO:K02161]
116057925  actr10; actin-related protein 10 [KO:K16576]
116057942  arf6a; ADP-ribosylation factor 6a [KO:K07941]
116058036  flna; filamin-A isoform X1 [KO:K04437]
116058049  nfkb1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
116058221  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
116058705  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
116058852  jun; transcription factor AP-1 [KO:K04448]
116059209  [KO:K17260]
116059287  [KO:K02159]
116059313  cyth1a; cytohesin-1a isoform X1 [KO:K18441]
116059432  dnm2a; dynamin-3 isoform X1 [KO:K23484]
116059446  tubb4bl; tubulin beta-4B chain [KO:K07375]
116059491  arf2a; ADP-ribosylation factor 2a [KO:K07937]
116059515  [KO:K07374]
116059520  [KO:K07374]
116059532  [KO:K07374]
116059537  cyth3b; cytohesin-3 isoform X1 [KO:K18441]
116059544  [KO:K07374]
116059565  [KO:K04433] [EC:2.7.12.2]
116059567  [KO:K07374]
116059577  [KO:K07374]
116059713  [KO:K04392]
116059728  rab5c; ras-related protein Rab-5C [KO:K07889]
116060015  exoc4; exocyst complex component 4 isoform X1 [KO:K06111]
116060063  waslb; WASP like actin nucleation promoting factor b isoform X1 [KO:K23612]
116060125  pycard; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
116060282  [KO:K05759]
116060354  arpc5b; actin-related protein 2/3 complex subunit 5b [KO:K05754]
116060615  fbxo22; F-box only protein 22 [KO:K10302]
116060649  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
116060936  [KO:K04467] [EC:2.7.11.10]
116060978  exoc7; exocyst complex component 7 isoform X1 [KO:K07195]
116061043  tcf7l2; transcription factor 7-like 2 isoform X2 [KO:K04491]
116061143  arf2b; ADP-ribosylation factor 2b [KO:K07937]
116061169  map2k6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
116061247  casp7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
116061279  [KO:K18441]
116061315  [KO:K07889]
116061413  mylpfb; myosin light chain, phosphorylatable, fast skeletal muscle b [KO:K12758]
116061496  plekhm1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
116061611  nckap1; nck-associated protein 1 isoform X3 [KO:K05750]
116061666  [KO:K08847] [EC:2.7.11.1]
116061675  [KO:K08738]
116061725  [KO:K07374]
116061799  [KO:K17260]
116061815  [KO:K08847] [EC:2.7.11.1]
116061840  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
116062082  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
116062102  snx33; sorting nexin-33 [KO:K17923]
116062349  [KO:K07955]
116062819  [KO:K02159]
116062912  [KO:K03173] [EC:2.3.2.27]
116063023  tnfrsfa; tumor necrosis factor receptor superfamily, member a [KO:K04722]
116063029  mapk10; mitogen-activated protein kinase 10 isoform X10 [KO:K04440] [EC:2.7.11.24]
116063150  [KO:K04456] [EC:2.7.11.1]
116063305  fyco1a; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
116063461  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
116063865  mylpfa; myosin light chain, phosphorylatable, fast skeletal muscle a [KO:K12758]
116063940  [KO:K18441]
116063959  map2k4a; dual specificity mitogen-activated protein kinase kinase 4a isoform X1 [KO:K04430] [EC:2.7.12.2]
116064169  [KO:K10396] [EC:5.6.1.3]
116064329  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
116064365  rhogd; ras homolog gene family, member Gd [KO:K07863]
116064381  dctn4; dynactin subunit 4 isoform X1 [KO:K10426]
116064455  rab9b; ras-related protein Rab-9B [KO:K07900]
116064649  [KO:K04377]
116064778  dynll2b; dynein, light chain, LC8-type 2b [KO:K10418]
116064779  birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
116064858  [KO:K05733] [EC:2.7.11.1]
116064999  wasf3a; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
116065075  [KO:K23649]
116065226  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
116065273  actb2; actin, cytoplasmic 2 [KO:K05692]
116065383  dctn5; dynactin subunit 5 [KO:K10427]
116065490  [KO:K07374]
116065683  rock2a; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
116065706  nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b isoform X1 [KO:K04734]
116065757  [KO:K07375]
116065811  [KO:K04427] [EC:2.7.11.25]
116066021  snx9b; sorting nexin-9b isoform X1 [KO:K17923]
116066028  hsp90aa1.2; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [KO:K04079]
116066029  hsp90aa1.1; heat shock protein HSP 90-alpha 1 [KO:K04079]
116066146  acbd3; Golgi resident protein GCP60 isoform X1 [KO:K23935]
116066167  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
116066178  [KO:K04379]
116066239  dynlt1; dynein light chain Tctex-type 1 [KO:K10420]
116066292  fosab; v-fos FBJ murine osteosarcoma viral oncogene homolog Ab [KO:K04379]
116066344  [KO:K10168]
116066412  [KO:K17388] [EC:2.7.11.39]
116066426  hsp90ab1; heat shock protein HSP 90-beta isoform X1 [KO:K04079]
116066465  [KO:K07856]
116066623  nod1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
116066820  elmo2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
116066840  rab5aa; ras-related protein Rab-5A [KO:K07887]
116066855  il6; interleukin-6 [KO:K05405]
116066904  [KO:K10415]
116066918  [KO:K02105]
116066973  dync1li1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
116067014  elmo1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
116067149  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
116067388  zgc:153993; apoptosis regulator BAX [KO:K02159]
116067450  mapk14b; mitogen-activated protein kinase 14B isoform X1 [KO:K04441] [EC:2.7.11.24]
116067529  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
116067678  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
118493643  [KO:K02620]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
sluc04010  MAPK signaling pathway
sluc04210  Apoptosis
sluc04217  Necroptosis
sluc04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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