KEGG   PATHWAY: cgob04810
Entry
cgob04810                   Pathway                                
Name
Regulation of actin cytoskeleton - Cottoperca gobio
Class
Cellular Processes; Cell motility
Pathway map
cgob04810  Regulation of actin cytoskeleton
cgob04810

Other DBs
GO: 0030036
Organism
Cottoperca gobio [GN:cgob]
Gene
115003454  [KO:K17388] [EC:2.7.11.39]
115003498  [KO:K08007]
115003605  [KO:K27976]
115003615  wasf1; LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 1 [KO:K05753]
115003653  pak5; serine/threonine-protein kinase PAK 5 isoform X1 [KO:K05736] [EC:2.7.11.1]
115003796  [KO:K03916]
115004006  chrm5; muscarinic acetylcholine receptor M5 [KO:K04133]
115004494  [KO:K05759]
115004518  diaph3; protein diaphanous homolog 3 isoform X1 [KO:K05745]
115004580  [KO:K18584]
115004618  [KO:K05735] [EC:2.7.11.1]
115004798  [KO:K06484]
115004857  fgf4; fibroblast growth factor 4 [KO:K04358]
115004922  [KO:K06482]
115004947  [KO:K01313] [EC:3.4.21.5]
115004955  [KO:K01313] [EC:3.4.21.5]
115005248  [KO:K00922] [EC:2.7.1.153]
115005369  [KO:K04132]
115005439  fgd1; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720]
115005816  fgf3; fibroblast growth factor 3 [KO:K04358]
115005943  [KO:K03994]
115005974  mylk; myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
115006129  [KO:K07860]
115006173  [KO:K04291]
115006184  [KO:K04359]
115006196  [KO:K04291]
115006252  fgf19; fibroblast growth factor 19 [KO:K22603]
115006385  [KO:K05717]
115006602  [KO:K00907] [EC:2.7.11.18]
115006641  pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
115006676  [KO:K02085]
115006742  pdgfra; LOW QUALITY PROTEIN: platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
115006815  [KO:K00922] [EC:2.7.1.153]
115006873  [KO:K02649]
115006889  pfn2; profilin-2 isoform X1 [KO:K05759]
115006899  [KO:K05768]
115007241  map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
115007299  fgf22; fibroblast growth factor 22 [KO:K04358]
115007307  [KO:K03898]
115007421  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
115007466  [KO:K02649]
115007473  [KO:K04347]
115007491  pak2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
115007725  [KO:K05757]
115007730  itga7; integrin alpha-7 [KO:K06583]
115007880  [KO:K12755]
115007984  [KO:K05704] [EC:2.7.10.2]
115008038  gna12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
115008052  [KO:K04513]
115008171  nckap1l; LOW QUALITY PROTEIN: nck-associated protein 1-like [KO:K05750]
115008190  [KO:K10351]
115008230  [KO:K00920] [EC:2.7.1.149]
115008238  [KO:K04513]
115008239  [KO:K05760]
115008278  [KO:K05755]
115008370  brk1; protein BRICK1 [KO:K05752]
115008732  [KO:K06484]
115008776  [KO:K05755]
115008836  [KO:K04393]
115009184  fgf6; fibroblast growth factor 6 [KO:K04358]
115009210  [KO:K23612]
115009342  [KO:K05730]
115009454  [KO:K06587]
115009461  kras; GTPase KRas [KO:K07827]
115009535  hras; GTPase HRas [KO:K02833]
115009748  [KO:K17457]
115009820  [KO:K04130]
115009830  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
115009884  myh11; myosin-11 isoform X1 [KO:K10352]
115009962  [KO:K05726]
115010252  [KO:K22428]
115010449  [KO:K04393]
115010471  [KO:K04366] [EC:2.7.11.1]
115010517  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
115010684  [KO:K05704] [EC:2.7.10.2]
115010688  [KO:K04513]
115010789  [KO:K04513]
115010790  [KO:K04513]
115011128  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
115011164  [KO:K05722]
115011195  [KO:K00920] [EC:2.7.1.149]
115011595  [KO:K00907] [EC:2.7.11.18]
115011622  [KO:K04392]
115011690  [KO:K04291]
115011719  [KO:K10352]
115011751  [KO:K10352]
115012144  [KO:K06493]
115012147  [KO:K04358]
115012229  [KO:K04639]
115012242  [KO:K05718]
115012253  mylpf; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
115012254  [KO:K04371] [EC:2.7.11.24]
115012286  [KO:K10352]
115012308  [KO:K05757]
115012331  [KO:K07827]
115012363  rras; ras-related protein R-Ras [KO:K07830]
115012367  [KO:K05627]
115012614  [KO:K04347]
115012743  actb; actin, cytoplasmic 1 [KO:K05692]
115012768  [KO:K04359]
115013012  [KO:K04362] [EC:2.7.10.1]
115013135  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
115013154  [KO:K17457]
115013163  [KO:K02649]
115013228  iqgap2; ras GTPase-activating-like protein IQGAP2 [KO:K05767]
115013252  [KO:K05757]
115013378  [KO:K00889] [EC:2.7.1.68]
115013400  [KO:K03996]
115013460  mapk1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
115013484  [KO:K10351]
115013545  fgf10; fibroblast growth factor 10 [KO:K04358]
115013581  fgf17; fibroblast growth factor 17 [KO:K04358]
115013612  f2r; proteinase-activated receptor 1 [KO:K03914]
115013716  [KO:K05760]
115013829  itga2; integrin alpha-2 isoform X1 [KO:K06481]
115013888  fgf5; fibroblast growth factor 5 [KO:K04358]
115013934  ssh1; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
115014055  [KO:K10031]
115014063  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
115014117  limk2; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
115014303  egf; LOW QUALITY PROTEIN: pro-epidermal growth factor [KO:K04357]
115014325  lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
115014339  cfl1; cofilin-1 [KO:K05765]
115014348  [KO:K04358]
115014370  [KO:K04358]
115014386  [KO:K05763]
115014442  cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
115014467  diaph1; protein diaphanous homolog 1 isoform X1 [KO:K05745]
115014482  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
115014523  arhgef6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729]
115014596  [KO:K10352]
115014599  [KO:K26108]
115014625  [KO:K10352]
115014635  [KO:K04358]
115014680  pdgfc; platelet-derived growth factor C isoform X1 [KO:K05450]
115014703  fgf16; fibroblast growth factor 16 isoform X1 [KO:K04358]
115014705  fgf2; fibroblast growth factor 2 [KO:K18497]
115014730  [KO:K18496]
115014733  pdgfrb; LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
115014742  [KO:K04526]
115015010  [KO:K06485]
115015013  [KO:K05741]
115015171  [KO:K04358]
115015172  [KO:K05764]
115015182  [KO:K04358]
115015367  [KO:K04393]
115015393  [KO:K27976]
115015440  [KO:K00889] [EC:2.7.1.68]
115015521  [KO:K05742]
115015881  wasf2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
115015974  [KO:K05725] [EC:2.7.10.2]
115016132  itgb8; integrin beta-8 [KO:K06591]
115016372  gsn; gelsolin isoform X1 [KO:K05768]
115016473  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
115016511  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
115016532  c6; complement component C6 [KO:K03995]
115016577  vav2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
115016623  crkl; crk-like protein [KO:K04438]
115016667  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
115016732  [KO:K17260]
115016765  lpar1; lysophosphatidic acid receptor 1 [KO:K04289]
115016840  c9; LOW QUALITY PROTEIN: complement component C9 [KO:K04000]
115016864  itga1; integrin alpha-1 [KO:K06480]
115016995  [KO:K03914]
115017158  [KO:K03996]
115017167  [KO:K00889] [EC:2.7.1.68]
115017290  pdgfd; platelet-derived growth factor D isoform X1 [KO:K05450]
115017391  [KO:K05699]
115017408  pak4; serine/threonine-protein kinase PAK 4 isoform X1 [KO:K05734] [EC:2.7.11.1]
115017523  git1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
115017525  [KO:K04456] [EC:2.7.11.1]
115017526  [KO:K04513]
115017569  ssh2; protein phosphatase Slingshot homolog 2 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
115017573  arhgap35; rho GTPase-activating protein 35 [KO:K05732]
115017742  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
115017845  arhgef12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
115017848  pak1; LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
115017856  [KO:K05093] [EC:2.7.10.1]
115017889  abi2; abl interactor 2 isoform X1 [KO:K05751]
115017891  [KO:K05743] [EC:2.7.11.1]
115017907  [KO:K04438]
115017933  [KO:K05093] [EC:2.7.10.1]
115018152  tiam1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
115018585  ins; insulin [KO:K04526]
115018604  [KO:K04456] [EC:2.7.11.1]
115018608  [KO:K05733] [EC:2.7.11.1]
115018668  [KO:K05732]
115018698  fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
115018706  msn; moesin [KO:K05763]
115018739  [KO:K18584]
115018867  [KO:K05731]
115018887  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
115019070  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
115019204  [KO:K04438]
115019338  [KO:K05743] [EC:2.7.11.1]
115019345  fgf1; fibroblast growth factor 1 isoform X1 [KO:K18496]
115019444  [KO:K05089] [EC:2.7.10.1]
115019468  [KO:K05692]
115019690  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
115019788  nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
115019820  [KO:K04456] [EC:2.7.11.1]
115019937  [KO:K05700]
115019976  [KO:K10031]
115020082  [KO:K05765]
115020095  [KO:K04358]
115020211  [KO:K05765]
115020374  [KO:K06585]
115020393  [KO:K13710]
115020477  actr2; actin-related protein 2 isoform X1 [KO:K17260]
115020479  [KO:K04131]
115020513  [KO:K05762]
115020725  itga8; LOW QUALITY PROTEIN: integrin alpha-8 [KO:K06584]
115020751  [KO:K04393]
115020983  [KO:K12330]
115020992  slc9a1; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
115021104  [KO:K04393]
115021192  ptk2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
115021224  [KO:K00889] [EC:2.7.1.68]
115021537  itga10; integrin alpha-10 [KO:K06586]
115021572  [KO:K05627]
115021681  [KO:K04132]
115022050  c8b; complement component C8 beta chain [KO:K03998]
115022094  [KO:K05754]
115022195  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
115022380  [KO:K12757]
115022421  [KO:K00922] [EC:2.7.1.153]
115022449  [KO:K05768]
115022485  [KO:K04361] [EC:2.7.10.1]
115022522  [KO:K04369] [EC:2.7.12.2]
115022533  [KO:K04347]
115022535  [KO:K06485]
115022626  [KO:K04189]
115022645  [KO:K02649]
115022807  [KO:K05730]
115022872  c8a; complement component C8 alpha chain [KO:K03997]
115022891  [KO:K00907] [EC:2.7.11.18]
115022893  [KO:K00889] [EC:2.7.1.68]
115022974  rock1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
115023125  [KO:K05719]
115023127  [KO:K05719]
115023418  [KO:K17260]
115023613  [KO:K06269] [EC:3.1.3.16]
115024221  rac3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
115024255  [KO:K05627]
115024258  [KO:K06493]
115024308  [KO:K06269] [EC:3.1.3.16]
115024321  [KO:K12758]
115024368  dock1; dedicator of cytokinesis protein 1 isoform X1 [KO:K13708]
115024458  rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
115024502  itga3; integrin alpha-3 isoform X1 [KO:K06482]
115024530  [KO:K00907] [EC:2.7.11.18]
115024810  vcl; vinculin [KO:K05700]
115024811  [KO:K04131]
115024992  itgb4; LOW QUALITY PROTEIN: integrin beta-4 [KO:K06525]
115025003  [KO:K06461]
115025027  [KO:K04639]
115025061  fgf21; fibroblast growth factor 21 isoform X1 [KO:K22429]
115025236  mos; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
115025255  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
115025287  [KO:K05769]
115025330  fam49b; protein FAM49B isoform X1 [KO:K27976]
115025400  vav3; LOW QUALITY PROTEIN: guanine nucleotide exchange factor VAV3 [KO:K05730]
115025471  iqgap1; ras GTPase-activating-like protein IQGAP1 [KO:K16848]
115025475  itgb1; integrin beta-1 [KO:K05719]
115025550  [KO:K05769]
115025647  [KO:K12757]
115025720  rras2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
115025748  c8g; complement component C8 gamma chain [KO:K03999]
115025932  cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
115026057  arhgef7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710]
115026080  [KO:K05717]
115026107  mras; ras-related protein M-Ras [KO:K07831]
115026115  itgb5; integrin beta-5 [KO:K06588]
115026146  [KO:K06464]
115026170  [KO:K05762]
115026222  itga6; LOW QUALITY PROTEIN: integrin alpha-6 [KO:K06485]
115026283  fgf7; fibroblast growth factor 7 [KO:K04358]
115026296  itga4; integrin alpha-4 isoform X1 [KO:K06483]
115026324  [KO:K18584]
115026392  pikfyve; LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
115026597  [KO:K26108]
115026717  [KO:K04358]
115026773  itgb6; integrin beta-6 isoform X1 [KO:K06589]
115027034  ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
115027137  rock2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
115027139  [KO:K05094] [EC:2.7.10.1]
115027245  [KO:K03099]
115027295  [KO:K08007]
115027360  [KO:K03916]
115027436  [KO:K04133]
115027525  [KO:K03916]
115027669  [KO:K03916]
115027708  [KO:K03916]
115027720  [KO:K04456] [EC:2.7.11.1]
115027787  actn1; alpha-actinin-1 isoform X1 [KO:K05699]
115027897  [KO:K05735] [EC:2.7.11.1]
115028109  [KO:K04130]
115028155  ppp1r12a; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
115028324  wasl; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
115028355  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
115028356  itga11; integrin alpha-11 [KO:K06587]
115028556  fgf23; fibroblast growth factor 23 [KO:K22428]
115028558  [KO:K04358]
115028836  enah; protein enabled homolog isoform X1 [KO:K05746]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
cgob04010  MAPK signaling pathway
cgob04510  Focal adhesion
cgob04520  Adherens junction
KO pathway
ko04810   

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