KEGG   PATHWAY: mmur04024
Entry
mmur04024                   Pathway                                
Name
cAMP signaling pathway - Microcebus murinus (gray mouse lemur)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
mmur04024  cAMP signaling pathway
mmur04024

Other DBs
GO: 0019933
Organism
Microcebus murinus (gray mouse lemur) [GN:mmur]
Gene
105854956  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
105854983  PDE4C; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
105855026  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
105855093  EDN2; endothelin-2 [KO:K16367]
105855101  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
105855107  CRHR2; corticotropin-releasing factor receptor 2 [KO:K04579]
105855129  [KO:K09047]
105855140  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
105855414  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
105855425  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
105855502  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
105855821  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
105855914  CRH; corticoliberin [KO:K05256]
105856433  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
105856500  RYR2; ryanodine receptor 2 isoform X1 [KO:K04962]
105856532  F2R; proteinase-activated receptor 1 [KO:K03914]
105856600  [KO:K06269] [EC:3.1.3.16]
105856969  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
105857027  PLN; cardiac phospholamban [KO:K05852]
105858096  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
105858210  [KO:K02183]
105858406  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
105858448  HTR4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
105858458  ADRB2; beta-2 adrenergic receptor [KO:K04142]
105858560  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
105858849  FOS; proto-oncogene c-Fos [KO:K04379]
105858882  [KO:K00232] [EC:1.3.3.6]
105859108  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
105859314  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
105859636  SSTR5; somatostatin receptor type 5 [KO:K04221]
105859653  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
105859673  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
105859788  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
105859934  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
105859992  CACNA1S; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
105860097  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
105860148  BDNF; brain-derived neurotrophic factor isoform X1 [KO:K04355]
105860184  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
105860240  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 [KO:K00232] [EC:1.3.3.6]
105860338  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
105860711  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
105860742  AMH; muellerian-inhibiting factor [KO:K04665]
105860786  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
105860836  HCN2; LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
105860971  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
105861032  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
105861035  ADCYAP1; pituitary adenylate cyclase-activating polypeptide isoform X1 [KO:K05262]
105861093  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105861452  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
105861596  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
105861711  SOX9; transcription factor SOX-9 [KO:K18435]
105861780  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2 [KO:K04345] [EC:2.7.11.11]
105862111  VIP; VIP peptides isoform X1 [KO:K05264]
105862135  PTCH1; protein patched homolog 1 [KO:K06225]
105862170  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
105862220  [KO:K01540]
105862465  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
105862632  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
105862660  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
105862683  ATP1A4; sodium/potassium-transporting ATPase subunit alpha-4 isoform X1 [KO:K01539] [EC:7.2.2.13]
105862687  [KO:K01539] [EC:7.2.2.13]
105862784  ADORA2A; adenosine receptor A2a [KO:K04266]
105863369  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
105863388  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
105863538  SLC9A1; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
105863582  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
105863630  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
105863640  CGA; glycoprotein hormones alpha chain [KO:K08522]
105863672  CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
105863738  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105863975  VAV3; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
105864008  GNAI3; guanine nucleotide-binding protein G(k) subunit alpha [KO:K04630]
105864291  [KO:K04440] [EC:2.7.11.24]
105864304  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
105864722  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
105864953  POPDC3; popeye domain-containing protein 3 isoform X1 [KO:K26207]
105864988  BVES; blood vessel epicardial substance [KO:K21108]
105864995  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
105865025  DRD2; D(2) dopamine receptor isoform X1 [KO:K04145]
105865255  EDN1; endothelin-1 [KO:K16366]
105865371  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
105865603  [KO:K08521]
105865636  GRIN2D; glutamate receptor ionotropic, NMDA 2D isoform X1 [KO:K05212]
105865643  RRAS; ras-related protein R-Ras isoform X1 [KO:K07829]
105865738  CAMK4; calcium/calmodulin-dependent protein kinase type IV isoform X1 [KO:K05869] [EC:2.7.11.17]
105865754  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
105865848  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
105865916  OXT; oxytocin-neurophysin 1 [KO:K05243]
105866139  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
105866168  LHCGR; lutropin-choriogonadotropic hormone receptor isoform X1 [KO:K04248]
105866617  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
105866672  SSTR2; somatostatin receptor type 2 [KO:K04218]
105867016  CALM2; calmodulin [KO:K02183]
105867270  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
105867325  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
105867474  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
105867497  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
105867692  PTGER2; prostaglandin E2 receptor EP2 subtype isoform X1 [KO:K04259]
105867785  FSHB; follitropin subunit beta [KO:K05250]
105867868  TSHR; thyrotropin receptor isoform X1 [KO:K04249]
105867963  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
105867991  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
105868011  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
105868044  [KO:K06269] [EC:3.1.3.16]
105868083  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
105868113  ADORA1; adenosine receptor A1 [KO:K04265]
105868229  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
105868254  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
105868281  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
105868864  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
105868940  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
105868958  GCG; glucagon isoform X1 [KO:K05259]
105868976  OXTR; oxytocin receptor [KO:K04229]
105869065  GHRL; appetite-regulating hormone isoform X1 [KO:K05254]
105869145  [KO:K11265] [EC:4.6.1.1]
105869370  CFTR; cystic fibrosis transmembrane conductance regulator isoform X1 [KO:K05031] [EC:5.6.1.6]
105869541  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
105869569  CALM3; calmodulin [KO:K02183]
105869683  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
105869763  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
105870050  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
105870055  [KO:K02183]
105870668  ADCY1; LOW QUALITY PROTEIN: adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
105870697  [KO:K04371] [EC:2.7.11.24]
105871124  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
105872106  PPP1R1B; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
105872349  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
105872776  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
105872832  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
105873244  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
105873434  CALML4; calmodulin-like protein 4 [KO:K02183]
105873750  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
105873786  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
105873936  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
105873938  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
105874161  ABCC4; multidrug resistance-associated protein 4 isoform X1 [KO:K05673]
105874305  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
105874510  EDN3; endothelin-3 isoform X1 [KO:K05227]
105874518  [KO:K04632]
105874520  [KO:K04632]
105874755  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
105874790  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
105874819  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
105874961  RHOA; transforming protein RhoA [KO:K04513]
105874990  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
105875072  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
105875389  ADRB1; beta-1 adrenergic receptor [KO:K04141]
105875898  NPY; pro-neuropeptide Y [KO:K05232]
105876068  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X1 [KO:K01538]
105876291  CALM1; calmodulin [KO:K02183]
105876557  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
105876685  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
105876768  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105876930  FFAR2; free fatty acid receptor 2 [KO:K04328]
105876941  FXYD1; phospholemman [KO:K13360]
105877194  TNNI3; troponin I, cardiac muscle [KO:K12044]
105877318  PDE4D; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
105877483  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
105877507  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
105877681  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
105877796  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
105877849  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
105877867  AFDN; afadin isoform X1 [KO:K05702]
105877977  GLI1; zinc finger protein GLI1 [KO:K16797]
105878067  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
105878326  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
105878474  BAD; bcl2-associated agonist of cell death [KO:K02158]
105878496  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
105878531  RELA; transcription factor p65 isoform X1 [KO:K04735]
105878570  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
105878705  TSHB; thyrotropin subunit beta [KO:K05251]
105878770  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
105878912  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
105879218  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X2 [KO:K05853] [EC:7.2.2.10]
105879268  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
105879338  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
105879489  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2 [KO:K04515] [EC:2.7.11.17]
105879870  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
105879920  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
105879994  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
105880000  RRAS2; ras-related protein R-Ras2 [KO:K07830]
105880123  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 [KO:K05731]
105880217  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
105880477  DRD1; D(1A) dopamine receptor [KO:K04144]
105880580  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
105880732  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
105880820  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
105880835  [KO:K08402]
105880884  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
105880911  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
105880919  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
105880930  PPP1CC; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
105880992  RAP1B; ras-related protein Rap-1b [KO:K07836]
105881031  [KO:K04513]
105881219  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
105881765  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
105881838  EDNRA; endothelin-1 receptor [KO:K04197]
105881855  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
105881883  ADCY10; LOW QUALITY PROTEIN: adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
105881918  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
105882004  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
105882219  GRIN1; glutamate receptor ionotropic, NMDA 1 [KO:K05208]
105882585  JUN; transcription factor AP-1 [KO:K04448]
105882598  GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1 [KO:K05209]
105882651  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
105882676  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
105882715  NPPA; natriuretic peptides A [KO:K12334]
105882731  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
105882816  PDE3A; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
105883245  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
105883459  CNGA4; cyclic nucleotide-gated cation channel alpha-4 isoform X1 [KO:K04951]
105883667  CNGA3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
105883746  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
105884011  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
105884236  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
105884309  POMC; pro-opiomelanocortin [KO:K05228]
105884349  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
105884438  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
105884723  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
105884745  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
105885051  SST; somatostatin [KO:K05237]
105885084  GIP; gastric inhibitory polypeptide isoform X1 [KO:K05258]
105885209  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
105885589  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
105885735  [KO:K04515] [EC:2.7.11.17]
105885869  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
105885913  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
105885942  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
105885964  SUCNR1; succinate receptor 1 [KO:K10042]
105886063  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
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Cell Calcium 55:385-393 (2014)
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Biochemistry (Mosc) 76:981-98 (2011)
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Related
pathway
mmur00071  Fatty acid degradation
mmur04015  Rap1 signaling pathway
mmur04020  Calcium signaling pathway
mmur04151  PI3K-Akt signaling pathway
mmur04210  Apoptosis
mmur04260  Cardiac muscle contraction
mmur04340  Hedgehog signaling pathway
mmur04720  Long-term potentiation
mmur04740  Olfactory transduction
mmur04972  Pancreatic secretion
mmur04976  Bile secretion
KO pathway
ko04024   

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