KEGG   PATHWAY: panu04060
Entry
panu04060                   Pathway                                
Name
Cytokine-cytokine receptor interaction - Papio anubis (olive baboon)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
panu04060  Cytokine-cytokine receptor interaction
panu04060

Organism
Papio anubis (olive baboon) [GN:panu]
Gene
100126695  GHR; growth hormone receptor precursor [KO:K05080]
100126710  CCR5; C-C chemokine receptor type 5 [KO:K04180]
100126711  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
100126717  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
100126719  IL12A; interleukin-12 subunit alpha precursor [KO:K05406]
100126724  IFNG; interferon gamma precursor [KO:K04687]
100126743  CSF2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
100126745  PRL; prolactin isoform X2 [KO:K05439]
100126747  IL4; interleukin-4 precursor [KO:K05430]
100126754  IL2; interleukin-2 precursor [KO:K05429]
100126758  GH1; somatotropin precursor [KO:K05438]
100137199  IL3; interleukin-3 precursor [KO:K04736]
100137220  IL5; interleukin-5 [KO:K05428]
100137221  IL13; interleukin-13 precursor [KO:K05435]
100137225  GDF9; growth/differentiation factor 9 precursor [KO:K22673]
100137244  IL10RB; interleukin-10 receptor subunit beta precursor [KO:K05135]
100137245  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
100137246  IFNGR2; interferon gamma receptor 2 precursor [KO:K05133]
100137480  GDF5; growth/differentiation factor 5 precursor [KO:K04664]
100137490  INHA; inhibin alpha chain precursor [KO:K05500]
100137545  IFNAR2; interferon alpha/beta receptor 2 precursor [KO:K05131]
100137596  BMP4; bone morphogenetic protein 4 precursor [KO:K04662]
100196937  TNFRSF9; tumor necrosis factor receptor superfamily member 9 [KO:K05146]
100303658  CD4; LOW QUALITY PROTEIN: T-cell surface glycoprotein CD4 [KO:K06454]
100379157  GHV; growth hormone variant precursor [KO:K05438]
100381193  CSH1; chorionic somatomammotropin hormone precursor [KO:K05438]
100381195  IL6; interleukin-6 precursor [KO:K05405]
100381196  CXCL8; interleukin-8 precursor [KO:K10030]
100381197  CCL2; C-C motif chemokine 2 precursor [KO:K14624]
100510871  [KO:K05408]
100997116  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
100997167  IL17RC; interleukin-17 receptor C isoform X4 [KO:K05166]
100997198  IL17F; interleukin-17F isoform X2 [KO:K05494]
100997333  [KO:K05506]
100997339  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
100997351  [KO:K05480]
100997425  CCL15; C-C motif chemokine 15 [KO:K05511]
100997478  GDF6; growth/differentiation factor 6 [KO:K20012]
100997515  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
100997643  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
100997847  INHBC; inhibin beta C chain [KO:K22688]
100998012  CCL14; C-C motif chemokine 14 [KO:K21092]
100998203  INHBE; inhibin beta E chain [KO:K22689]
100998383  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
100998449  NGF; beta-nerve growth factor isoform X2 [KO:K02582]
100998471  IL1RAP; interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
100998690  IL33; interleukin-33 [KO:K12967]
100998698  CCL18; C-C motif chemokine 18 [KO:K21094]
100999056  [KO:K05438]
100999149  IL36B; interleukin-36 beta isoform X1 [KO:K05486]
100999522  IL1RN; interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
101000210  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
101000289  [KO:K04737]
101000303  MPL; thrombopoietin receptor isoform X4 [KO:K05082]
101000353  IL17D; interleukin-17D [KO:K05492]
101000704  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
101000722  IL31RA; interleukin-31 receptor subunit alpha isoform X1 [KO:K22630]
101000763  IL31; interleukin-31 [KO:K22631]
101000831  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
101001096  [KO:K10031]
101001125  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
101001341  BMP8B; bone morphogenetic protein 8B isoform X1 [KO:K16622]
101001402  IL20RA; interleukin-20 receptor subunit alpha isoform X2 [KO:K05136]
101001420  CCL28; C-C motif chemokine 28 isoform X1 [KO:K05513]
101001423  RELL2; RELT-like protein 2 isoform X3 [KO:K26541]
101001633  IL21; interleukin-21 [KO:K05434]
101001708  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
101001830  THPO; thrombopoietin isoform X2 [KO:K06854]
101002040  LIF; leukemia inhibitory factor isoform X1 [KO:K05419]
101002063  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
101002133  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
101002143  CD40; tumor necrosis factor receptor superfamily member 5 precursor [KO:K03160]
101002309  CCR4; C-C chemokine receptor type 4 [KO:K04179]
101002483  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B isoform X2 [KO:K04722]
101002577  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
101002587  IL9; interleukin-9 [KO:K05432]
101002623  TNFRSF18; tumor necrosis factor receptor superfamily member 18 [KO:K05154]
101002648  CNTF; ciliary neurotrophic factor [KO:K05420]
101002896  IFNK; interferon kappa [KO:K05441]
101003010  CCL21; C-C motif chemokine 21 [KO:K16062]
101003015  [KO:K05474]
101003106  TNFSF4; tumor necrosis factor ligand superfamily member 4 isoform X1 [KO:K05469]
101003144  [KO:K22669]
101003176  [KO:K12964]
101003199  MSTN; growth/differentiation factor 8 [KO:K05497]
101003327  IL1R2; interleukin-1 receptor type 2 isoform X1 [KO:K04387]
101003350  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B isoform X2 [KO:K05150]
101003409  TNFRSF10C; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 10C [KO:K22701]
101003417  BMPR1A; bone morphogenetic protein receptor type-1A isoform X1 [KO:K04673] [EC:2.7.11.30]
101003425  OSM; oncostatin-M isoform X2 [KO:K05418]
101003583  CCL19; C-C motif chemokine 19 [KO:K05512]
101003626  IL17B; interleukin-17B [KO:K05490]
101003660  TNFRSF4; tumor necrosis factor receptor superfamily member 4 isoform X1 [KO:K05142]
101003680  [KO:K05507]
101003843  IFNL1; interferon lambda-1 [KO:K05447]
101003876  IL15RA; interleukin-15 receptor subunit alpha [KO:K05074]
101003909  IL1R1; interleukin-1 receptor type 1 [KO:K04386]
101004108  TNFRSF10A; tumor necrosis factor receptor superfamily member 10A isoform X1 [KO:K04722]
101004203  CX3CL1; fractalkine [KO:K05508]
101004271  ACVR2B; activin receptor type-2B isoform X3 [KO:K13596] [EC:2.7.11.30]
101004275  ACKR4; atypical chemokine receptor 4 [KO:K04186]
101004334  IL34; interleukin-34 [KO:K22633]
101004383  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
101004466  [KO:K22702]
101004576  IL2RA; interleukin-2 receptor subunit alpha isoform X3 [KO:K05068]
101004703  IL7; interleukin-7 isoform X1 [KO:K05431]
101004733  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
101004755  [KO:K16598]
101004811  [KO:K22702]
101004917  IL25; interleukin-25 isoform X1 [KO:K05493]
101004984  CCL24; C-C motif chemokine 24 [KO:K21097]
101005025  CCL22; C-C motif chemokine 22 [KO:K21095]
101005086  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
101005107  CCL27; C-C motif chemokine 27 [KO:K16598]
101005212  [KO:K04177]
101005375  IL27; interleukin-27 subunit alpha isoform X2 [KO:K22629]
101005377  CCL17; C-C motif chemokine 17 [KO:K21083]
101005440  IL18RAP; interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
101005651  ACVR1C; activin receptor type-1C isoform X1 [KO:K13568] [EC:2.7.11.30]
101005712  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
101005797  CCR3; C-C chemokine receptor type 3 isoform X1 [KO:K04178]
101006004  LEPR; leptin receptor isoform X1 [KO:K05062]
101006338  IL17RA; interleukin-17 receptor A [KO:K05164]
101006406  CD70; CD70 antigen [KO:K05470]
101006461  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
101006538  IL17C; interleukin-17C [KO:K05491]
101006603  CCL26; C-C motif chemokine 26 [KO:K21096]
101006627  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
101006955  IL15; interleukin-15 isoform X2 [KO:K05433]
101007076  AMH; muellerian-inhibiting factor [KO:K04665]
101007077  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
101007168  CNTFR; ciliary neurotrophic factor receptor subunit alpha isoform X2 [KO:K05059]
101007535  EBI3; interleukin-27 subunit beta [KO:K24476]
101007662  TSLP; thymic stromal lymphopoietin [KO:K05436]
101007735  CCR1; C-C chemokine receptor type 1 [KO:K04176]
101007758  CCL11; eotaxin [KO:K16597]
101007792  LIFR; leukemia inhibitory factor receptor isoform X1 [KO:K05058]
101007971  IL1RL2; interleukin-1 receptor-like 2 isoform X3 [KO:K05172]
101008087  XCR1; chemokine XC receptor 1 [KO:K04193]
101008110  CCL7; C-C motif chemokine 7 isoform X1 [KO:K05509]
101008254  BMPR1B; bone morphogenetic protein receptor type-1B isoform X2 [KO:K13578] [EC:2.7.11.30]
101008476  CCL8; C-C motif chemokine 8 [KO:K16596]
101008599  TNFSF13B; tumor necrosis factor ligand superfamily member 13B isoform X1 [KO:K05476]
101008737  OSMR; oncostatin-M-specific receptor subunit beta isoform X2 [KO:K05057]
101008827  CCL13; C-C motif chemokine 13 [KO:K16595]
101008944  EPOR; erythropoietin receptor [KO:K05079]
101008957  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
101008968  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
101008996  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B [KO:K05143]
101009030  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
101009167  CCL1; C-C motif chemokine 1 [KO:K05514]
101009253  TGFB2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
101009331  CCL25; C-C motif chemokine 25 isoform X3 [KO:K13072]
101009394  CCR10; C-C chemokine receptor type 10 [KO:K04185]
101009691  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
101009748  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
101009794  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
101010036  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C isoform X1 [KO:K05151]
101010100  CXCL11; C-X-C motif chemokine 11 isoform X1 [KO:K12672]
101010376  IL9R; interleukin-9 receptor isoform X2 [KO:K05073]
101010530  BMP10; bone morphogenetic protein 10 [KO:K22670]
101010543  CCR9; C-C chemokine receptor type 9 [KO:K04184]
101010826  CXCL9; C-X-C motif chemokine 9 [KO:K05416]
101011005  IL26; interleukin-26 [KO:K05446]
101011007  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X4 [KO:K05160]
101011100  CD40LG; CD40 ligand [KO:K03161]
101011268  BMP6; bone morphogenetic protein 6 [KO:K16620]
101011344  IL22; interleukin-22 isoform X2 [KO:K05445]
101011371  IL18; interleukin-18 isoform X1 [KO:K05482]
101011494  RELT; tumor necrosis factor receptor superfamily member 19L isoform X2 [KO:K05156]
101011618  IL11RA; interleukin-11 receptor subunit alpha isoform X1 [KO:K05056]
101011696  IL23A; interleukin-23 subunit alpha isoform X2 [KO:K05426]
101011937  IL23R; interleukin-23 receptor [KO:K05065]
101012178  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
101012647  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
101012692  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
101012956  GDF15; growth/differentiation factor 15 [KO:K05504]
101013171  EPO; erythropoietin [KO:K05437]
101013543  TNFSF8; tumor necrosis factor ligand superfamily member 8 isoform X1 [KO:K05471]
101013600  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
101013835  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
101014353  IL10RA; interleukin-10 receptor subunit alpha isoform X2 [KO:K05134]
101014488  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
101014637  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
101014683  IL2RB; interleukin-2 receptor subunit beta isoform X4 [KO:K05069]
101014736  TNFRSF19; tumor necrosis factor receptor superfamily member 19 isoform X2 [KO:K05155]
101014795  [KO:K03159]
101014968  LEP; leptin isoform X1 [KO:K05424]
101015191  CLCF1; cardiotrophin-like cytokine factor 1 isoform X2 [KO:K05421]
101015260  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
101015395  GDF3; growth/differentiation factor 3 [KO:K22672]
101015443  CSF3; granulocyte colony-stimulating factor isoform X1 [KO:K05423]
101015502  CD27; CD27 antigen isoform X2 [KO:K05144]
101015564  BMP5; bone morphogenetic protein 5 [KO:K04663]
101015690  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X8 [KO:K05063]
101015788  IFNE; interferon epsilon [KO:K05442]
101016009  IL20RB; interleukin-20 receptor subunit beta isoform X1 [KO:K05137]
101016512  TGFBR1; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
101016516  [KO:K05414]
101016626  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
101016702  NODAL; nodal homolog [KO:K04666]
101016725  CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453]
101016756  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
101017180  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
101017363  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
101017773  CXCR1; C-X-C chemokine receptor type 1 isoform X1 [KO:K04175]
101017918  [KO:K05414]
101018287  [KO:K05414]
101018335  IL16; pro-interleukin-16 isoform X1 [KO:K22628]
101018566  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
101018652  [KO:K05414]
101018829  BMP7; bone morphogenetic protein 7 [KO:K16621]
101019008  [KO:K05414]
101019094  ACKR3; atypical chemokine receptor 3 [KO:K04304]
101019223  INHBB; inhibin beta B chain [KO:K22687]
101019380  [KO:K05414]
101019627  IL11; interleukin-11 [KO:K05417]
101019678  ACVRL1; serine/threonine-protein kinase receptor R3 isoform X1 [KO:K13594] [EC:2.7.11.30]
101019906  BMPR2; bone morphogenetic protein receptor type-2 isoform X1 [KO:K04671] [EC:2.7.11.30]
101020000  EDA2R; tumor necrosis factor receptor superfamily member 27 isoform X1 [KO:K05163]
101020032  GDF11; growth/differentiation factor 11 [KO:K22679]
101020254  ACVR1B; activin receptor type-1B isoform X2 [KO:K13567] [EC:2.7.11.30]
101020255  AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 [KO:K04672] [EC:2.7.11.30]
101021158  GDF10; growth/differentiation factor 10 [KO:K22674]
101021520  GDF2; growth/differentiation factor 2 [KO:K05503]
101021706  [KO:K05414]
101021910  IL22RA1; interleukin-22 receptor subunit alpha-1 isoform X2 [KO:K05138]
101021959  BMP3; bone morphogenetic protein 3 [KO:K05496]
101021968  CTF1; cardiotrophin-1 isoform X2 [KO:K05422]
101022031  IL24; interleukin-24 [KO:K22668]
101022257  IFNLR1; interferon lambda receptor 1 isoform X1 [KO:K05140]
101022304  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
101022542  CCR7; C-C chemokine receptor type 7 isoform X1 [KO:K04182]
101022672  IL4R; interleukin-4 receptor subunit alpha isoform X4 [KO:K05071]
101022800  [KO:K05505]
101023088  IL1A; interleukin-1 alpha isoform X1 [KO:K04383]
101023107  TGFBR2; TGF-beta receptor type-2 isoform X2 [KO:K04388] [EC:2.7.11.30]
101023118  [KO:K05414]
101023149  CXCL5; C-X-C motif chemokine 5 [KO:K05506]
101023216  GDF7; growth/differentiation factor 7 [KO:K20013]
101023329  IL20; interleukin-20 [KO:K22667]
101023386  IL21R; interleukin-21 receptor isoform X3 [KO:K05075]
101023446  IL1B; interleukin-1 beta [KO:K04519]
101023496  CCR6; C-C chemokine receptor type 6 isoform X2 [KO:K04181]
101023614  CXCL17; C-X-C motif chemokine 17 isoform X2 [KO:K22627]
101023678  IL19; LOW QUALITY PROTEIN: interleukin-19 [KO:K05444]
101023739  [KO:K24382]
101023803  IL37; interleukin-37 [KO:K05485]
101023828  [KO:K05414]
101024175  IFNW1; interferon omega-1 [KO:K05440]
101024270  IL10; interleukin-10 [KO:K05443]
101024346  CRLF2; cytokine receptor-like factor 2 [KO:K05078]
101024420  RELL1; RELT-like protein 1 isoform X1 [KO:K26541]
101024506  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
101024523  IFNB1; interferon beta [KO:K05415]
101024554  [KO:K05505]
101024608  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
101024628  IL36G; interleukin-36 gamma isoform X1 [KO:K05487]
101024834  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X2 [KO:K05141]
101024850  IL6R; interleukin-6 receptor subunit alpha [KO:K05055]
101025106  INHBA; inhibin beta A chain [KO:K04667]
101025190  BMP2; bone morphogenetic protein 2 [KO:K21283]
101025236  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
101025271  PPBP; platelet basic protein [KO:K10029]
101025339  IL36A; interleukin-36 alpha [KO:K05484]
101025455  CCL5; C-C motif chemokine 5 isoform X1 [KO:K12499]
101025537  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X3 [KO:K05145]
101025986  BMP15; bone morphogenetic protein 15 [KO:K05498]
101026034  IL1F10; interleukin-1 family member 10 [KO:K05488]
101026064  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
101026165  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
101026520  CCL16; C-C motif chemokine 16 isoform X1 [KO:K21093]
101026663  CXCL1; growth-regulated alpha protein [KO:K05505]
101026802  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
101026878  [KO:K05511]
101026887  IL17A; interleukin-17A [KO:K05489]
101026988  CCR8; C-C chemokine receptor type 8 [KO:K04183]
101027022  PF4V1; platelet factor 4 variant isoform X2 [KO:K05407]
103876540  [KO:K05050]
103878629  TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X1 [KO:K05475]
103879991  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
103883773  BMP8A; bone morphogenetic protein 8A isoform X1 [KO:K16622]
103884403  [KO:K05505]
110741124  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
110741552  [KO:K05438]
116268823  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
116268824  [KO:K03159]
116270026  [KO:K05414]
116273100  [KO:K05163]
116274104  [KO:K05506]
116276357  [KO:K05062]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
PMID:23847622
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
PMID:21349428
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
PMID:17530315
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
PMID:24381786
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
PMID:18926762
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
PMID:21155715
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
PMID:22410872
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
PMID:12949498
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
PMID:12189384
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
PMID:26115564
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
PMID:23612460
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
PMID:22710174
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
KO pathway
ko04060   

DBGET integrated database retrieval system