KEGG   PATHWAY: cang05169
Entry
cang05169                   Pathway                                
Name
Epstein-Barr virus infection - Colobus angolensis palliatus (Angola colobus)
Description
Epstein-Barr virus (EBV) is a gamma-herpes virus that widely infects human populations predominantly at an early age but remains mostly asymptomatic. EBV has been linked to a wide spectrum of human malignancies, including nasopharyngeal carcinoma and other hematologic cancers, like Hodgkin's lymphoma, Burkitt's lymphoma (BL), B-cell immunoblastic lymphoma in HIV patients, and posttransplant-associated lymphoproliferative diseases.  EBV has the unique ability to establish life-long latent infection in primary human B lymphocytes. During latent infection, EBV expresses a small subset of genes, including 6 nuclear antigens (EBNA-1, -2, -3A, -3B, -3C, and -LP), 3 latent membrane proteins (LMP-1, -2A, and -2B), 2 small noncoding RNAs (EBER-1 and 2). On the basis of these latent gene expression, three different latency patterns associated with the types of cancers are recognized.
Class
Human Diseases; Infectious disease: viral
Pathway map
cang05169  Epstein-Barr virus infection
cang05169

Organism
Colobus angolensis palliatus (Angola colobus) [GN:cang]
Gene
105508888  CR2; complement receptor type 2 isoform X1 [KO:K04012]
105505618  CD19; B-lymphocyte antigen CD19 isoform X1 [KO:K06465]
105501359  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
105501360  HLA class II histocompatibility antigen, DQ alpha 2 chain isoform X1 [KO:K06752]
105501361  HLA class II histocompatibility antigen, DRB1-4 beta chain-like [KO:K06752]
105502761  HLA class II histocompatibility antigen, DRB1-4 beta chain isoform X1 [KO:K06752]
105513785  mamu class II histocompatibility antigen, DR alpha chain isoform X1 [KO:K06752]
105513786  HLA class II histocompatibility antigen, DRB1-10 beta chain isoform X1 [KO:K06752]
105513788  HLA class II histocompatibility antigen, DRB1-9 beta chain isoform X1 [KO:K06752]
105513789  HLA class II histocompatibility antigen, DQ alpha 2 chain isoform X1 [KO:K06752]
105513790  HLA class II histocompatibility antigen, DQ beta 1 chain-like isoform X1 [KO:K06752]
105513791  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
105513797  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
105513798  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
105513800  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
105513801  HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
105513802  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
105514240  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105514272  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105514273  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105524473  toll-like receptor 2 [KO:K10159]
105519819  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
105507588  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
105521650  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
105510802  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
105527764  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
105515555  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
105511739  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
105507149  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
105525125  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
105527033  IKBKG; NF-kappa-B essential modulator [KO:K07210]
105500419  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
105512675  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
105512156  RELA; transcription factor p65 [KO:K04735]
105513728  TNF; tumor necrosis factor [KO:K03156]
105513330  IL6; interleukin-6 isoform X1 [KO:K05405]
105516444  DDX58; probable ATP-dependent RNA helicase DDX58 [KO:K12646] [EC:5.6.2.6]
105512800  MAVS; mitochondrial antiviral-signaling protein [KO:K12648]
105518439  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
105502730  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
105509453  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
105503197  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
105514764  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
105503436  interferon alpha-1/13 [KO:K05414]
105503438  IFNA8; interferon alpha-8 [KO:K05414]
105503439  IFNA2; interferon alpha-2 [KO:K05414]
105503440  interferon alpha-1/13-like [KO:K05414]
105503441  interferon alpha-1/13-like [KO:K05414]
105503442  interferon alpha-6 [KO:K05414]
105503444  IFNA14; interferon alpha-14 [KO:K05414]
105503445  interferon alpha-4 [KO:K05414]
105503446  interferon alpha-4-like [KO:K05414]
105503447  interferon alpha-17-like [KO:K05414]
105503449  interferon alpha-10 [KO:K05414]
105503452  IFNB1; interferon beta [KO:K05415]
105524762  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
105524754  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
105510845  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
105520874  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
105507777  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
105500610  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
105503733  IRF9; interferon regulatory factor 9 isoform X1 [KO:K04693]
105507534  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
105502273  OAS1; 2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
105502274  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
105502275  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
105501322  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
105522006  ISG15; ubiquitin-like protein ISG15 isoform X1 [KO:K12159]
105515921  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
105512314  FADD; FAS-associated death domain protein [KO:K02373]
105517408  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
105514348  BID; BH3-interacting domain death agonist [KO:K04726]
105519653  BCL2L11; bcl-2-like protein 11 [KO:K16341]
105520028  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
105514789  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
105514219  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
105521896  cytochrome c-like [KO:K08738]
105509147  cytochrome c-like [KO:K08738]
105509351  cytochrome c [KO:K08738]
105516629  cytochrome c-like [KO:K08738]
105506411  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
105510236  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
105524344  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
105511227  uncharacterized protein LOC105511227 [KO:K10785]
105511417  uncharacterized protein LOC105511417 [KO:K10785]
105501091  CD3E; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
105501092  CD3G; T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
105501093  CD3D; T-cell surface glycoprotein CD3 delta chain isoform X1 [KO:K06450]
105505536  CD247; T-cell surface glycoprotein CD3 zeta chain isoform X1 [KO:K06453]
105501704  PSMC2; 26S protease regulatory subunit 7 [KO:K03061]
105517297  PSMC1; 26S protease regulatory subunit 4 [KO:K03062]
105520594  26S protease regulatory subunit 4-like [KO:K03062]
105520745  26S protease regulatory subunit 4 [KO:K03062]
105519171  PSMC4; 26S protease regulatory subunit 6B isoform X1 [KO:K03063]
105510878  26S protease regulatory subunit 10B-like [KO:K03064]
105525976  PSMC6; 26S protease regulatory subunit 10B [KO:K03064]
105527136  PSMC3; 26S protease regulatory subunit 6A [KO:K03065]
105515976  PSMC5; 26S protease regulatory subunit 8 [KO:K03066]
105514460  26S proteasome non-ATPase regulatory subunit 2 [KO:K03028]
105518834  PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1 [KO:K03032]
105503108  PSMD3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033]
105517795  PSMD12; 26S proteasome non-ATPase regulatory subunit 12 isoform X1 [KO:K03035]
105508735  PSMD11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036]
105515383  PSMD6; LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 6 [KO:K03037]
105525795  PSMD7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038]
105503182  PSMD13; 26S proteasome non-ATPase regulatory subunit 13 isoform X1 [KO:K03039]
105508868  PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029]
105515320  PSMD14; 26S proteasome non-ATPase regulatory subunit 14 [KO:K03030]
105519129  PSMD8; 26S proteasome non-ATPase regulatory subunit 8 isoform X1 [KO:K03031]
105506381  ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1 [KO:K06691]
105512768  SHFM1; 26S proteasome complex subunit DSS1 isoform X1 [KO:K10881]
105513792  TAP1; antigen peptide transporter 1 isoform X1 [KO:K05653] [EC:7.4.2.14]
105513794  TAP2; antigen peptide transporter 2 isoform X1 [KO:K05654] [EC:7.4.2.14]
105514232  TAPBP; tapasin isoform X1 [KO:K08058]
105511093  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
105520787  CALR; calreticulin [KO:K08057]
105500736  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
105513804  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513823  mamu class I histocompatibility antigen, alpha chain F-like isoform X1 [KO:K06751]
105513934  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
105513935  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513936  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
105513982  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E-like [KO:K06751]
105513984  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [KO:K06751]
105513986  HLA class I histocompatibility antigen, B-67 alpha chain-like [KO:K06751]
105513995  LOW QUALITY PROTEIN: histocompatibility antigen-related [KO:K06751]
105511106  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
105517104  SNW1; SNW domain-containing protein 1 isoform X1 [KO:K06063]
105505141  SIN3A; paired amphipathic helix protein Sin3a [KO:K11644]
105506760  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
105521274  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
105516290  NCOR2; nuclear receptor corepressor 2 [KO:K06065]
105513147  CIR1; LOW QUALITY PROTEIN: corepressor interacting with RBPJ 1 [KO:K06066]
105502445  RBPJL; recombining binding protein suppressor of hairless-like protein isoform X1 [KO:K06053]
105507218  RBPJ; recombining binding protein suppressor of hairless isoform X1 [KO:K06053]
105525534  HES1; transcription factor HES-1 [KO:K06054]
105512912  FCER2; low affinity immunoglobulin epsilon Fc receptor isoform X1 [KO:K06468]
105521414  RUNX3; runt-related transcription factor 3 isoform X1 [KO:K09279]
105509076  MYC; myc proto-oncogene protein [KO:K04377]
105525661  USP7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
105502659  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
105523626  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
105514162  CDKN1A; cyclin-dependent kinase inhibitor 1 isoform X1 [KO:K06625]
105508083  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1 [KO:K04402]
105516011  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
105527649  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X1 [KO:K04402]
105527128  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
105524119  POLK; DNA polymerase kappa [KO:K03511] [EC:2.7.7.7]
105509216  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
105523405  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
105523708  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
105507333  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
105524169  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
105500411  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
105515019  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
105518411  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105519178  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
105521497  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105510391  MAP3K14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
105526900  RELB; transcription factor RelB [KO:K09253]
105507106  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
105504584  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
105519218  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
105524887  NFKBIE; LOW QUALITY PROTEIN: NF-kappa-B inhibitor epsilon [KO:K05872]
105505414  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
105512966  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
105517705  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
105518701  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
105519528  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
105522700  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
105507091  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
105526517  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
105505905  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
105511987  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
105512012  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
105514175  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
105514260  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
105511418  JUN; transcription factor AP-1 [KO:K04448]
105522665  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [KO:K01510] [EC:3.6.1.5]
105518119  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
105518296  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
105502405  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
105510793  CD44; CD44 antigen isoform X1 [KO:K06256]
105505725  ITGAL; integrin alpha-L [KO:K05718]
105505291  CD58; lymphocyte function-associated antigen 3 [KO:K06492]
105520876  ICAM1; intercellular adhesion molecule 1 [KO:K06490]
105527562  VIM; vimentin [KO:K07606]
105526163  TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X1 [KO:K11859] [EC:3.4.19.12]
105500328  JAK3; tyrosine-protein kinase JAK3 [KO:K11218] [EC:2.7.10.2]
105503009  STAT3; signal transducer and activator of transcription 3 [KO:K04692]
105508677  LYN; tyrosine-protein kinase Lyn isoform X1 [KO:K05854] [EC:2.7.10.2]
105516007  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
105510638  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
105506322  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
105514391  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
105509184  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105525086  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 isoform X1 [KO:K06856]
105525098  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105525110  uncharacterized protein LOC105525110 [KO:K06856]
105525116  uncharacterized protein LOC105525116 [KO:K06856]
105520681  BTK; tyrosine-protein kinase BTK isoform X1 [KO:K07370] [EC:2.7.10.2]
105518287  BLNK; B-cell linker protein isoform X1 [KO:K07371]
105511970  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
105513491  SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
105520264  CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1 [KO:K06624]
105512055  CCND1; G1/S-specific cyclin-D1 isoform X1 [KO:K04503]
105503930  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
105513014  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
105500487  CDK4; cyclin-dependent kinase 4 isoform X1 [KO:K02089] [EC:2.7.11.22]
105521035  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
105516411  CCNA2; cyclin-A2 [KO:K06627]
105512542  CCNA1; cyclin-A1 isoform X1 [KO:K06627]
105508203  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
105516826  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
105500566  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
105510064  RB1; retinoblastoma-associated protein [KO:K06618]
105525035  E2F1; transcription factor E2F1 [KO:K17454]
105514294  E2F2; transcription factor E2F2 [KO:K09389]
105526691  E2F3; transcription factor E2F3 [KO:K06620]
Compound
C00076  Calcium cation
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
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Young LS, Rickinson AB.
  Title
Epstein-Barr virus: 40 years on.
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Nat Rev Cancer 4:757-68 (2004)
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Reference
PMID:21372216
  Authors
Saha A, Robertson ES
  Title
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes.
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Clin Cancer Res 17:3056-63 (2011)
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Reference
PMID:21429244
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Ning S
  Title
Innate immune modulation in EBV infection.
  Journal
Herpesviridae 2:1 (2011)
DOI:10.1186/2042-4280-2-1
Reference
PMID:28408983
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Stanfield BA, Luftig MA
  Title
Recent advances in understanding Epstein-Barr virus.
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F1000Res 6:386 (2017)
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Reference
PMID:24586164
  Authors
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME
  Title
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.
  Journal
PLoS Pathog 10:e1003960 (2014)
DOI:10.1371/journal.ppat.1003960
Reference
PMID:23850008
  Authors
Rajsbaum R, Garcia-Sastre A
  Title
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways.
  Journal
Trends Microbiol 21:421-9 (2013)
DOI:10.1016/j.tim.2013.06.006
Reference
PMID:25704559
  Authors
Hoffmann HH, Schneider WM, Rice CM
  Title
Interferons and viruses: an evolutionary arms race of molecular interactions.
  Journal
Trends Immunol 36:124-38 (2015)
DOI:10.1016/j.it.2015.01.004
Reference
PMID:22110506
  Authors
Spender LC, Inman GJ
  Title
Inhibition of germinal centre apoptotic programmes by epstein-barr virus.
  Journal
Adv Hematol 2011:829525 (2011)
DOI:10.1155/2011/829525
Reference
PMID:23303627
  Authors
Fu Q, He C, Mao ZR
  Title
Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells.
  Journal
J Zhejiang Univ Sci B 14:8-24 (2013)
DOI:10.1631/jzus.B1200189
Reference
PMID:29116588
  Authors
Wang Y, Banerjee S, Ding L, Cai C, Wei F, Cai Q
  Title
The regulatory role of protein phosphorylation in human gammaherpesvirus associated cancers.
  Journal
Virol Sin 32:357-368 (2017)
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Related
pathway
cang03050  Proteasome
cang04010  MAPK signaling pathway
cang04020  Calcium signaling pathway
cang04064  NF-kappa B signaling pathway
cang04110  Cell cycle
cang04115  p53 signaling pathway
cang04210  Apoptosis
cang04612  Antigen processing and presentation
cang04620  Toll-like receptor signaling pathway
cang04622  RIG-I-like receptor signaling pathway
cang04630  JAK-STAT signaling pathway
cang04662  B cell receptor signaling pathway
KO pathway
ko05169   
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