KEGG   PATHWAY: shab05132
Entry
shab05132                   Pathway                                
Name
Salmonella infection - Strigops habroptila (Kakapo)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
shab05132  Salmonella infection
shab05132

Organism
Strigops habroptila (Kakapo) [GN:shab]
Gene
115605878  PODXL; podocalyxin isoform X1 [KO:K06817]
115611199  PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
115604163  RAB5A; ras-related protein Rab-5A isoform X1 [KO:K07887]
115618719  RAB5B; ras-related protein Rab-5B [KO:K07888]
115617600  RAB5C; ras-related protein Rab-5C [KO:K07889]
115619678  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
115614340  RAB7A; ras-related protein Rab-7a [KO:K07897]
115602364  RAB7B; ras-related protein Rab-7b [KO:K07898]
115617899  PLEKHM1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
115616404  VPS11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
115610585  VPS16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
115606900  VPS18; vacuolar protein sorting-associated protein 18 homolog isoform X1 [KO:K20181]
115614237  VPS33A; vacuolar protein sorting-associated protein 33A isoform X1 [KO:K20182]
115606493  VPS39; vam6/Vps39-like protein isoform X1 [KO:K20183]
115612492  VPS41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
115601878  RILP; rab-interacting lysosomal protein isoform X1 [KO:K13883]
115607574  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
115603640  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 isoform X1 [KO:K10414]
115610639  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
115608561  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
115619096  cytoplasmic dynein 1 light intermediate chain 2-like isoform X1 [KO:K10416]
115619451  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
115619869  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
115613586  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 isoform X1 [KO:K10417]
115601901  DYNLL2; dynein light chain 2, cytoplasmic isoform X1 [KO:K10418]
115614441  dynein light chain 1, cytoplasmic-like [KO:K10418]
115614442  dynein light chain 1, cytoplasmic [KO:K10418]
115601364  DYNLRB2; dynein light chain roadblock-type 2 isoform X1 [KO:K10419]
115615107  DYNLRB1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
115613500  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
115604076  DYNLT3; dynein light chain Tctex-type 3 isoform X1 [KO:K10420]
115610584  DCTN1; dynactin subunit 1 isoform X1 [KO:K04648]
115618756  DCTN2; dynactin subunit 2 isoform X1 [KO:K10424]
115619525  DCTN3; dynactin subunit 3 [KO:K10425]
115615451  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
115606785  DCTN5; dynactin subunit 5 [KO:K10427]
115605010  DCTN6; dynactin subunit 6 [KO:K10428]
115608983  ACTR1A; alpha-centractin [KO:K16575]
115606711  actin-related protein 10 isoform X1 [KO:K16576]
115611153  tubulin alpha-3 chain isoform X1 [KO:K07374]
115605668  tubulin alpha-3 chain [KO:K07374]
115605713  tubulin alpha-3 chain-like [KO:K07374]
115605750  TUBA8; tubulin alpha-8 chain isoform X1 [KO:K07374]
115605751  tubulin alpha-2 chain [KO:K07374]
115618641  TUBA1A; tubulin alpha-1A chain [KO:K07374]
115618643  tubulin alpha-1B chain [KO:K07374]
115618644  tubulin alpha-1C chain [KO:K07374]
115608292  tubulin alpha-4A chain-like [KO:K07374]
115608293  tubulin alpha-5 chain [KO:K07374]
115602249  tubulin alpha-8 chain [KO:K07374]
115604599  TUBB6; tubulin beta-6 chain isoform X1 [KO:K07375]
115617253  TUBB4B; tubulin beta-4B chain [KO:K07375]
115619541  TUBB3; tubulin beta-3 chain [KO:K07375]
115615075  TUBB1; tubulin beta-1 chain isoform X1 [KO:K07375]
115615078  tubulin beta-2 chain [KO:K07375]
115603458  TUBB; tubulin beta chain [KO:K07375]
115619912  FYCO1; FYVE and coiled-coil domain-containing protein 1 isoform X1 [KO:K21954]
115605379  ADP-ribosylation factor-like protein 8B [KO:K07955]
115614274  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
115602276  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
115617434  PLEKHM2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
115618741  KIF5A; kinesin heavy chain isoform X1 [KO:K10396]
115609003  KIF5C; kinesin heavy chain [KO:K10396]
115615688  KIF5B; kinesin-1 heavy chain isoform X1 [KO:K10396]
115606528  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
115613596  KLC4; kinesin light chain 4 isoform X1 [KO:K10407]
115613839  ACBD3; Golgi resident protein GCP60 [KO:K23935]
115614455  RHOA; transforming protein RhoA [KO:K04513]
115605820  M6PR; cation-dependent mannose-6-phosphate receptor [KO:K10089]
115604143  RAB9A; ras-related protein Rab-9A isoform X1 [KO:K07899]
115612905  RAB9B; ras-related protein Rab-9B [KO:K07900]
115603993  GCC2; GRIP and coiled-coil domain-containing protein 2 isoform X1 [KO:K20282]
115611935  PFN2; profilin-2 isoform X1 [KO:K05759]
115613704  PFN3; profilin-3 [KO:K05759]
115616640  EXOC7; exocyst complex component 7 isoform X1 [KO:K07195]
115606727  EXOC5; exocyst complex component 5 isoform X1 [KO:K19984]
115605780  EXOC4; exocyst complex component 4 isoform X1 [KO:K06111]
115604271  EXOC2; exocyst complex component 2 isoform X1 [KO:K17637]
115618823  RALA; ras-related protein Ral-A [KO:K07834]
115616751  ACTG1; actin, cytoplasmic 2 [KO:K05692]
115612443  actin, cytoplasmic type 5 [KO:K05692]
115606888  ACTB; actin, cytoplasmic 1 [KO:K05692]
115602698  S100A10; protein S100-A10 [KO:K17274]
115613147  ANXA2; annexin A2 [KO:K17092]
115603512  AHNAK; neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
115607339  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
115611476  ARHGEF26; rho guanine nucleotide exchange factor 26 [KO:K13744]
115602258  RHOG; rho-related GTP-binding protein RhoG [KO:K07863]
115603078  rho-related GTP-binding protein RhoG-like [KO:K07863]
115604182  ELMO1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
115615023  ELMO2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
115609284  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
115614657  MYL2; LOW QUALITY PROTEIN: myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
115615234  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
115602058  MYL10; myosin regulatory light chain 10 isoform X1 [KO:K12756]
115612260  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1 [KO:K12757]
115612266  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
115603061  myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
115617517  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
115607090  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
115607898  NCKAP1; nck-associated protein 1 isoform X1 [KO:K05750]
115603099  NCKAP1L; nck-associated protein 1-like [KO:K05750]
115615587  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
115604411  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
115619164  ABI1; abl interactor 1 isoform X1 [KO:K23649]
115614718  BRK1; protein BRICK1 [KO:K05752]
115612690  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
115604326  WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
115610083  ACTR2; actin-related protein 2 [KO:K17260]
115604935  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
115608091  ACTR3; actin-related protein 3 isoform X1 [KO:K18584]
115606808  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
115606809  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
115608930  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
115614154  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
115614924  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
115617161  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
115611639  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
115604297  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
115612689  PAK3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
115609661  MYO6; unconventional myosin-VI [KO:K10358]
115611164  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
115611766  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
115617305  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
115605592  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
115605664  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
115606321  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
115602285  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
115605107  CYTH4; cytohesin-4 [KO:K18441]
115616559  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
115607093  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
115602906  cytohesin-2 [KO:K18441]
115606688  ARF6; ADP-ribosylation factor 6 [KO:K07941]
115616834  ARF1; ADP-ribosylation factor 1 [KO:K07937]
115612897  SNX33; sorting nexin-33 [KO:K17923]
115600946  SNX18; sorting nexin-18 [KO:K17923]
115618956  sorting nexin-18-like [KO:K17923]
115613457  SNX9; sorting nexin-9 isoform X1 [KO:K17923]
115605140  WASL; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
115603419  DNM2; LOW QUALITY PROTEIN: dynamin-2 [KO:K23484] [EC:3.6.5.5]
115610383  toll-like receptor 6 isoform X1 [KO:K10169]
115610854  TLR2; toll-like receptor 2 [KO:K10159]
115610981  toll-like receptor 2 type-2 isoform X1 [KO:K10159]
115616357  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
115609931  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
115617148  TLR4; toll-like receptor 4 [KO:K10160]
115613705  LY96; lymphocyte antigen 96 [KO:K05400]
115614025  TLR5; toll-like receptor 5 [KO:K10168]
115605130  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
115606662  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
115609308  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
115605620  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
115614010  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
115601316  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
115609102  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
115618527  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
115607032  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
115610509  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
115603474  RELA; LOW QUALITY PROTEIN: transcription factor p65 [KO:K04735]
115613482  NOD1; nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
115607573  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
115613648  HSP90AB1; heat shock protein HSP 90-beta isoform X1 [KO:K04079]
115605149  HSP90B1; endoplasmin isoform X1 [KO:K09487]
115619627  receptor-interacting serine/threonine-protein kinase 2-like isoform X1 [KO:K08846] [EC:2.7.11.1]
115610198  RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
115615408  CSE1L; exportin-2 [KO:K18423]
115601690  KPNA1; importin subunit alpha-5 [KO:K23940]
115611649  KPNA4; importin subunit alpha-3 [KO:K23583]
115602722  KPNA3; importin subunit alpha-4 isoform X1 [KO:K23583]
115603679  RPS3; 40S ribosomal protein S3 [KO:K02985]
115607639  HRAS; GTPase HRas [KO:K02833]
115614046  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
115612648  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
115618167  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
115614282  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
115607143  dual specificity mitogen-activated protein kinase kinase 3-like isoform X1 [KO:K04432] [EC:2.7.12.2]
115616735  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
115604848  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
115604850  MAPK11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
115602374  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
115602375  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
115616509  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
115603011  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
115610508  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
115608097  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
115615620  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
115606485  FOS; proto-oncogene c-Fos [KO:K04379]
115611576  JUN; transcription factor AP-1 [KO:K04448]
115618514  interleukin-1 beta-like isoform X1 [KO:K04519]
115607542  IL6; interleukin-6 [KO:K05405]
115605011  interleukin-8-like [KO:K10030]
115605013  interleukin-8-like [KO:K10030]
115605339  interleukin-8-like [KO:K10030]
115619830  CTNNB1; catenin beta-1 [KO:K02105]
115615905  TCF7; transcription factor 7 isoform X1 [KO:K02620]
115618453  TCF7L1; transcription factor 7-like 1 [KO:K04490]
115607965  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
115610292  LEF1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
115616653  MYC; myc proto-oncogene protein [KO:K04377]
115612491  FBXO22; F-box only protein 22 isoform X1 [KO:K10302]
115615908  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
115601685  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
115616900  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
115618941  tumor necrosis factor receptor type 1-associated DEATH domain protein-like [KO:K03171]
115619674  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
115603869  inhibitor of apoptosis protein-like isoform X1 [KO:K16060]
115615063  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
115601525  GAPDH; glyceraldehyde-3-phosphate dehydrogenase isoform X1 [KO:K00134] [EC:1.2.1.12]
115611740  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
115618487  tumor necrosis factor receptor superfamily member 10B-like isoform X1 [KO:K04722]
115607147  FADD; FAS-associated death domain protein [KO:K02373]
115607876  caspase-8-like [KO:K04398] [EC:3.4.22.61]
115608040  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
115602910  BAX; apoptosis regulator BAX [KO:K02159]
115602411  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
115607984  cytochrome c [KO:K08738]
115615414  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
115610967  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
115608896  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
115609562  RHOB; rho-related GTP-binding protein RhoB [KO:K07856]
115610430  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
115606664  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
115613872  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
115603334  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
115601097  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
115604915  TXN2; thioredoxin, mitochondrial isoform X1 [KO:K03671]
115601322  TXN; thioredoxin isoform X1 [KO:K03671]
115607697  NLRP6; NACHT, LRR and PYD domains-containing protein 6 [KO:K12800]
115602746  PYCARD; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
115603126  caspase-1-like isoform X1 [KO:K01370] [EC:3.4.22.36]
115616293  IL18; interleukin-18 isoform X1 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
shab04010  MAPK signaling pathway
shab04210  Apoptosis
shab04217  Necroptosis
shab04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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