KEGG   PATHWAY: phas04024
Entry
phas04024                   Pathway                                
Name
cAMP signaling pathway - Phyllostomus hastatus (greater spear-nosed bat)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
phas04024  cAMP signaling pathway
phas04024

Other DBs
GO: 0019933
Organism
Phyllostomus hastatus (greater spear-nosed bat) [GN:phas]
Gene
123804299  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 isoform X1 [KO:K01539] [EC:7.2.2.13]
123804401  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
123804403  VAV3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
123804635  RAP1A; ras-related protein Rap-1A [KO:K04353]
123804672  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
123804754  TSHB; thyrotropin subunit beta [KO:K05251]
123804840  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
123805328  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
123805534  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
123805699  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
123805709  CNGB1; cyclic nucleotide-gated cation channel beta-1 isoform X1 [KO:K04952]
123806400  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
123806569  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
123806670  ADORA2A; adenosine receptor A2a [KO:K04266]
123806765  DRD1; D(1A) dopamine receptor [KO:K04144]
123806785  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
123806902  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
123807045  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
123807056  ADRB2; beta-2 adrenergic receptor isoform X1 [KO:K04142]
123807079  [KO:K04498] [EC:2.3.1.48]
123807136  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
123807193  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
123807855  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
123808002  CALM1; calmodulin-1 [KO:K02183]
123808036  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
123808110  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
123808226  FOS; proto-oncogene c-Fos [KO:K04379]
123808451  TSHR; thyrotropin receptor [KO:K04249]
123808608  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
123808766  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
123809424  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 isoform X1 [KO:K01540]
123809425  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
123809456  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
123809801  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
123809987  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
123810006  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
123810038  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
123810054  BDNF; brain-derived neurotrophic factor isoform X1 [KO:K04355]
123810142  FSHB; follitropin subunit beta [KO:K05250]
123810187  RRAS2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
123810346  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
123810431  HTR4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
123810462  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
123811344  FSHR; follicle-stimulating hormone receptor [KO:K04247]
123811379  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
123811468  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
123811554  GLI3; transcriptional activator GLI3 [KO:K06230]
123811684  CNGA3; LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
123811737  CALM2; calmodulin-2 [KO:K02183]
123811789  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
123811797  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
123811809  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
123811828  GCG; pro-glucagon isoform X1 [KO:K05259]
123811891  NPY; pro-neuropeptide Y [KO:K05232]
123811930  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
123812057  CRHR2; corticotropin-releasing factor receptor 2 isoform X1 [KO:K04579]
123812393  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
123812417  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
123812719  RAP1B; ras-related protein Rap-1b [KO:K07836]
123812807  GLI1; zinc finger protein GLI1 [KO:K16797]
123812947  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
123813112  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
123813365  TNNI3; troponin I, cardiac muscle [KO:K12044]
123813423  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
123813552  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
123813639  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
123813640  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
123813679  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
123813723  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
123813766  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
123813918  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
123814055  EDNRA; endothelin-1 receptor [KO:K04197]
123814144  AMH; muellerian-inhibiting factor [KO:K04665]
123814146  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
123814193  [KO:K06231]
123814205  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
123814364  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
123814381  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
123814527  OXTR; oxytocin receptor [KO:K04229]
123814533  GHRL; appetite-regulating hormone isoform X1 [KO:K05254]
123814577  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
123814582  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
123814967  EDN3; endothelin-3 isoform X1 [KO:K05227]
123815116  [KO:K04632]
123815198  [KO:K05243]
123815292  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
123815319  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
123815475  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
123815647  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
123815893  DRD5; D(1B) dopamine receptor [KO:K05840]
123815957  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
123816025  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
123816169  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
123816243  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
123816316  [KO:K06230]
123816381  PTGER3; prostaglandin E2 receptor EP3 subtype [KO:K04260]
123816440  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
123816451  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
123816631  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
123817178  [KO:K05258]
123817336  SSTR2; somatostatin receptor type 2 [KO:K04218]
123817374  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
123817411  GRIN2C; glutamate receptor ionotropic, NMDA 2C isoform X1 [KO:K05211]
123817566  CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
123817647  SOX9; transcription factor SOX-9 [KO:K18435]
123817715  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
123817933  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
123818083  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
123818235  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
123818256  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
123818387  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
123818398  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
123818418  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
123818437  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
123818752  ABCC4; ATP-binding cassette sub-family C member 4 isoform X1 [KO:K05673]
123819322  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
123819437  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
123819667  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
123819804  DRD2; D(2) dopamine receptor isoform X1 [KO:K04145]
123820195  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
123820197  GRIN3A; glutamate receptor ionotropic, NMDA 3A isoform X1 [KO:K05213]
123820487  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
123820550  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
123820560  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
123820599  [KO:K01539] [EC:7.2.2.13]
123820887  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
123821009  [KO:K02183]
123821027  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
123821109  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
123821307  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
123821438  PLN; cardiac phospholamban [KO:K05852]
123821650  [KO:K11265] [EC:4.6.1.1]
123821719  POPDC3; popeye domain-containing protein 3 [KO:K26207]
123821745  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
123821754  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
123821902  [KO:K05264]
123821913  AFDN; afadin isoform X1 [KO:K05702]
123822019  CGA; glycoprotein hormones alpha chain [KO:K08522]
123822157  BVES; blood vessel epicardial substance [KO:K21108]
123822187  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
123822225  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
123822248  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
123822396  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
123822448  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
123822478  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
123822544  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
123822577  POMC; pro-opiomelanocortin [KO:K05228]
123822821  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
123822917  GIPR; gastric inhibitory polypeptide receptor [KO:K04580]
123823025  CALM3; calmodulin-3 [KO:K02183]
123823122  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
123823352  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
123823384  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
123823458  ORAI1; calcium release-activated calcium channel protein 1 isoform X1 [KO:K16056]
123823743  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
123823813  FFAR2; free fatty acid receptor 2 [KO:K04328]
123823912  FXYD1; phospholemman [KO:K13360]
123824015  EDN1; endothelin-1 [KO:K16366]
123824520  [KO:K04513]
123824527  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
123824671  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
123824765  CFTR; cystic fibrosis transmembrane conductance regulator isoform X1 [KO:K05031] [EC:5.6.1.6]
123824834  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
123824873  F2R; proteinase-activated receptor 1 [KO:K03914]
123824963  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
123825207  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
123825246  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
123825322  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
123825463  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
123825523  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
123825630  [KO:K04409] [EC:2.7.11.1]
123825676  SSTR5; somatostatin receptor type 5 [KO:K04221]
123825794  CNGB3; LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
123826011  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
123826024  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
123826168  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
123826281  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
123826750  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
123826755  SUCNR1; LOW QUALITY PROTEIN: succinate receptor 1 [KO:K10042]
123826776  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
123826843  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
123826967  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
123827268  SST; somatostatin [KO:K05237]
123827306  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
123827542  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
123827776  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
123827777  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
123827834  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
123827960  TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
123828120  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
123828245  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
123828247  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
123828274  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
123828291  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
123828777  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
123829013  ADRB1; beta-1 adrenergic receptor [KO:K04141]
123829223  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
123829336  BAD; bcl2-associated agonist of cell death [KO:K02158]
123829436  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
123829518  RELA; transcription factor p65 [KO:K04735]
123829523  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
123829653  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
123829665  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
123829775  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
123830290  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
123830304  RRAS; ras-related protein R-Ras [KO:K07829]
123830339  [KO:K08521]
123830380  RHOA; transforming protein RhoA [KO:K04513]
123830565  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123830671  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
123831226  CALML3; calmodulin-like protein 3 [KO:K02183]
123831240  [KO:K02183]
123831409  JUN; transcription factor AP-1 [KO:K04448]
123831818  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
123831845  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
123831907  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
123831922  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123832025  EDN2; endothelin-2 isoform X1 [KO:K16367]
123832118  NPPA; natriuretic peptides A [KO:K12334]
123832297  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
123832298  [KO:K02649]
123832317  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
123832334  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S isoform X1 [KO:K04857]
123832713  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F [KO:K04853]
123832904  RYR2; ryanodine receptor 2 isoform X1 [KO:K04962]
123832995  ADORA1; adenosine receptor A1 [KO:K04265]
123833057  CRH; corticoliberin isoform X1 [KO:K05256]
123833093  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
  Title
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Related
pathway
phas00071  Fatty acid degradation
phas04015  Rap1 signaling pathway
phas04020  Calcium signaling pathway
phas04151  PI3K-Akt signaling pathway
phas04210  Apoptosis
phas04260  Cardiac muscle contraction
phas04340  Hedgehog signaling pathway
phas04720  Long-term potentiation
phas04740  Olfactory transduction
phas04972  Pancreatic secretion
phas04976  Bile secretion
KO pathway
ko04024   

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