KEGG   PATHWAY: btax04024
Entry
btax04024                   Pathway                                
Name
cAMP signaling pathway - Budorcas taxicolor (takin)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
btax04024  cAMP signaling pathway
btax04024

Other DBs
GO: 0019933
Organism
Budorcas taxicolor (takin) [GN:btax]
Gene
128043399  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
128043403  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
128043471  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
128043489  SSTR5; somatostatin receptor type 5 [KO:K04221]
128043555  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
128043585  RAPGEF4; rap guanine nucleotide exchange factor 4 [KO:K04351]
128043638  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
128043800  GCG; pro-glucagon [KO:K05259]
128043941  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [KO:K05853] [EC:7.2.2.10]
128043958  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
128044333  [KO:K01539] [EC:7.2.2.13]
128044334  [KO:K01539] [EC:7.2.2.13]
128044413  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
128044424  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
128044447  JUN; transcription factor Jun [KO:K04448]
128044450  RAP1A; ras-related protein Rap-1A [KO:K04353]
128044465  PRKACB; cAMP-dependent protein kinase catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
128044474  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
128044567  RHOA; transforming protein RhoA [KO:K04513]
128044674  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
128044678  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
128044759  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
128044903  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
128045268  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
128045418  EDN2; endothelin-2 [KO:K16367]
128045676  TSHB; thyrotropin subunit beta [KO:K05251]
128045772  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
128045803  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
128046379  CRHR2; corticotropin-releasing factor receptor 2 [KO:K04579]
128046449  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
128046498  GLI3; transcriptional activator GLI3 [KO:K06230]
128046524  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
128046532  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
128046579  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
128046584  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
128046677  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor [KO:K04587]
128046764  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
128046774  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
128046777  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
128046967  NPY; pro-neuropeptide Y [KO:K05232]
128046969  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
128047085  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
128047244  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
128047362  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
128047405  PPP1R12A; protein phosphatase 1 regulatory subunit 12A [KO:K06270]
128047462  RAP1B; ras-related protein Rap-1b [KO:K07836]
128047488  TIAM1; rho guanine nucleotide exchange factor TIAM1 [KO:K05731]
128047516  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
128047601  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
128047602  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
128047644  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
128047663  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
128047858  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
128047997  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
128048017  GLI1; zinc finger protein GLI1 [KO:K16797]
128048064  RYR2; ryanodine receptor 2 [KO:K04962]
128048310  ATP2B1; plasma membrane calcium-transporting ATPase 1 [KO:K05850] [EC:7.2.2.10]
128048945  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
128049033  RAPGEF3; rap guanine nucleotide exchange factor 3 [KO:K08014]
128049417  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
128049427  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
128049619  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
128049625  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
128049935  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
128049943  DRD5; D(1B) dopamine receptor [KO:K05840]
128049951  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
128050339  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
128050350  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
128050356  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
128050386  GRIA1; glutamate receptor 1 [KO:K05197]
128050399  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha [KO:K04515] [EC:2.7.11.17]
128050452  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [KO:K12490]
128050540  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
128050664  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
128050828  VAV1; proto-oncogene vav [KO:K05730]
128050904  ADRB2; beta-2 adrenergic receptor [KO:K04142]
128051051  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
128051405  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
128051495  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
128051498  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
128051508  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
128051575  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
128051626  AMH; muellerian-inhibiting factor [KO:K04665]
128052044  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
128052107  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
128052214  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
128052265  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
128052308  PTCH1; protein patched homolog 1 [KO:K06225]
128053043  SUCNR1; succinate receptor 1 [KO:K10042]
128053254  POPDC3; popeye domain-containing protein 3 [KO:K26207]
128053353  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
128053365  AFDN; afadin isoform X1 [KO:K05702]
128053456  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
128053486  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
128053493  CGA; glycoprotein hormones alpha chain [KO:K08522]
128053518  OXTR; oxytocin receptor [KO:K04229]
128053520  VIP; VIP peptides [KO:K05264]
128053563  BVES; blood vessel epicardial substance [KO:K21108]
128053757  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
128053854  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
128053951  FOS; protein c-Fos [KO:K04379]
128054042  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
128054045  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
128054190  F2R; proteinase-activated receptor 1 [KO:K03914]
128054267  CALM1; calmodulin-1 [KO:K02183]
128054349  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
128054418  TSHR; thyrotropin receptor [KO:K04249]
128054518  DRD1; D(1A) dopamine receptor [KO:K04144]
128054531  GHRL; appetite-regulating hormone [KO:K05254]
128054611  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
128054855  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
128055110  GRIN1; glutamate receptor ionotropic, NMDA 1 [KO:K05208]
128055125  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
128055373  ROCK2; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.1]
128055501  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
128055872  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 [KO:K04615]
128056061  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
128056109  SST; somatostatin [KO:K05237]
128056360  EDN1; endothelin-1 isoform X1 [KO:K16366]
128056361  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
128056390  FSHR; follicle-stimulating hormone receptor [KO:K04247]
128056500  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
128056529  ATP2B2; plasma membrane calcium-transporting ATPase 2 [KO:K05850] [EC:7.2.2.10]
128056566  POMC; pro-opiomelanocortin [KO:K05228]
128056596  CNGA3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
128056684  CALM2; calmodulin-2 [KO:K02183]
128056822  [KO:K11265] [EC:4.6.1.1]
128056879  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
128057155  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
128057390  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
128057493  [KO:K05673]
128057513  [KO:K05673]
128057588  [KO:K05673]
128057589  [KO:K05673]
128057590  [KO:K05673]
128057591  [KO:K05673]
128057592  [KO:K05673]
128057593  [KO:K05673]
128057631  [KO:K05673]
128057632  [KO:K05673]
128057633  [KO:K05673]
128057705  [KO:K05673]
128057811  ABCC4; ATP-binding cassette sub-family C member 4 isoform X1 [KO:K05673]
128058230  [KO:K02183]
128058250  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas [KO:K04632]
128058295  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
128058573  EDN3; endothelin-3 [KO:K05227]
128058687  OXT; oxytocin-neurophysin 1 [KO:K05243]
128058829  [KO:K04632]
128059256  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
128059561  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
128059599  CRH; corticoliberin [KO:K05256]
128060054  RRAS2; ras-related protein R-Ras2 [KO:K07830]
128060086  GRIA4; glutamate receptor 4 [KO:K05200]
128060218  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
128060339  BDNF; brain-derived neurotrophic factor [KO:K04355]
128060385  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
128060490  DRD2; D(2) dopamine receptor [KO:K04145]
128060511  FSHB; follitropin subunit beta [KO:K05250]
128060953  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
128061188  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S isoform X1 [KO:K04857]
128061193  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
128061218  [KO:K04353]
128061259  NPPA; natriuretic peptides A [KO:K12334]
128061269  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
128061475  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
128061491  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128061581  ATP2B4; plasma membrane calcium-transporting ATPase 4 [KO:K05850] [EC:7.2.2.10]
128061611  KCNK2; potassium channel subfamily K member 2 [KO:K04913]
128061784  ADORA1; adenosine receptor A1 [KO:K04265]
128061813  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
128061892  [KO:K05850] [EC:7.2.2.10]
128062005  GRIA2; glutamate receptor 2 [KO:K05198]
128062068  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
128062160  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
128062181  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
128062284  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
128062357  EDNRA; endothelin-1 receptor [KO:K04197]
128062390  HHIP; hedgehog-interacting protein [KO:K06231]
128062418  ADORA2A; adenosine receptor A2a [KO:K04266]
128062552  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
128062615  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
128063034  FXYD1; phospholemman isoform X1 [KO:K13360]
128063078  RRAS; ras-related protein R-Ras [KO:K07829]
128063156  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
128063240  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
128063310  TNNI3; troponin I, cardiac muscle [KO:K12044]
128063420  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
128063465  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
128063641  SLC9A1; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
128063719  LHB; lutropin subunit beta [KO:K08521]
128063733  GIPR; gastric inhibitory polypeptide receptor [KO:K04580]
128063810  CALM3; calmodulin-3 [KO:K02183]
128063870  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128063966  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
128064139  [KO:K04328]
128064542  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
128064731  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
128065125  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
128065196  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
128065401  SSTR2; somatostatin receptor type 2 [KO:K04218]
128065432  GIP; gastric inhibitory polypeptide [KO:K05258]
128065457  CRHR1; corticotropin-releasing factor receptor 1 [KO:K04578]
128065484  PPP1R1B; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
128065487  SOX9; transcription factor SOX-9 [KO:K18435]
128065652  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [KO:K05853] [EC:7.2.2.10]
128065663  RAC3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
128066123  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
128066163  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
128066205  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
128066235  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
128066643  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
128066943  SSTR1; somatostatin receptor type 1 [KO:K04217]
128067048  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128067290  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
128067328  ROCK1; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.1]
128067499  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
128067565  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
128067568  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
128067818  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
128067942  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
128067997  ADRB1; beta-1 adrenergic receptor [KO:K04141]
128068496  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
128068503  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
128068546  RELA; transcription factor p65 [KO:K04735]
128068699  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128068977  BAD; bcl2-associated agonist of cell death [KO:K02158]
128068993  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
128069261  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
128069702  ATP2B3; plasma membrane calcium-transporting ATPase 3 [KO:K05850] [EC:7.2.2.10]
128069759  GRIA3; glutamate receptor 3 [KO:K05199]
128069887  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
128070004  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F [KO:K04853]
128070039  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
128070610  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
128071087  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
128071103  [KO:K05870]
128071129  [KO:K05673]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
  Title
cAMP and Ca signaling in secretory epithelia: Crosstalk and synergism.
  Journal
Cell Calcium 55:385-393 (2014)
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Related
pathway
btax00071  Fatty acid degradation
btax04015  Rap1 signaling pathway
btax04020  Calcium signaling pathway
btax04151  PI3K-Akt signaling pathway
btax04210  Apoptosis
btax04260  Cardiac muscle contraction
btax04340  Hedgehog signaling pathway
btax04720  Long-term potentiation
btax04740  Olfactory transduction
btax04972  Pancreatic secretion
btax04976  Bile secretion
KO pathway
ko04024   

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