KEGG   PATHWAY: cfa04060
Entry
cfa04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Canis lupus familiaris (dog)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
cfa04060  Cytokine-cytokine receptor interaction
cfa04060

Organism
Canis lupus familiaris (dog) [GN:cfa]
Gene
448788  CCL1; C-C motif chemokine 1 precursor [KO:K05514]
448798  CCL25; C-C motif chemokine 25 precursor [KO:K13072]
448793  CCL19; C-C motif chemokine 19 precursor [KO:K05512]
448796  CCL21; C-C motif chemokine 21 precursor [KO:K16062]
448787  CCL3; C-C motif chemokine 3 precursor [KO:K05408]
480600  c-C motif chemokine 3-like precursor [KO:K05408]
480601  regakine-1-like [KO:K05408]
448786  CCL4; C-C motif chemokine 4 precursor [KO:K12964]
403586  CCL17; C-C motif chemokine 17 precursor [KO:K21083]
100686212  CCL22; C-C motif chemokine 22 [KO:K21095]
403522  CCL5; C-C motif chemokine 5 precursor [KO:K12499]
448792  CCL8; C-C motif chemokine 8 precursor [KO:K16596]
480603  CCL14; C-C motif chemokine 14 [KO:K21092]
480604  CCL16; C-C motif chemokine 16 [KO:K21093]
480602  CCL23; C-C motif chemokine 15 isoform X2 [KO:K05511]
445451  CCL13; C-C motif chemokine 13 precursor [KO:K16595]
491148  CCL7; C-C motif chemokine 7 precursor [KO:K05509]
403981  CCL2; C-C motif chemokine 2 precursor [KO:K14624]
445452  CCL24; C-C motif chemokine 24 precursor [KO:K21097]
448789  CCL26; C-C motif chemokine 26 precursor [KO:K21096]
445454  CCL27; C-C motif chemokine 27 precursor [KO:K16598]
111098084  uncharacterized protein LOC111098084 [KO:K16598]
448795  CCL28; C-C motif chemokine 28 precursor [KO:K05513]
448790  CCL20; C-C motif chemokine 20 precursor [KO:K14625]
119874472  growth-regulated protein homolog gamma-like isoform X4 [KO:K05505]
119876918  growth-regulated protein homolog gamma-like isoform X3 [KO:K05505]
106557449  alveolar macrophage chemotactic factor-like [KO:K05506]
403850  CXCL8; interleukin-8 precursor [KO:K10030]
482196  PPBP; platelet basic protein precursor [KO:K10029]
478432  CXCL10; C-X-C motif chemokine 10 precursor [KO:K12671]
608156  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
449622  CXCL12; stromal cell-derived factor 1 isoform 1 precursor [KO:K10031]
607514  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
610078  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
111090090  CXCL17; C-X-C motif chemokine 17 isoform X1 [KO:K22627]
490356  lymphotactin isoform X16 [KO:K22675]
487265  CX3CL1; fractalkine precursor [KO:K05508]
403989  IL2; interleukin-2 precursor [KO:K05429]
403785  IL4; interleukin-4 precursor [KO:K05430]
751768  IL7; interleukin-7 precursor [KO:K05431]
100682918  IL9; interleukin-9 [KO:K05432]
403584  IL15; interleukin-15 [KO:K05433]
442935  IL21; interleukin-21 precursor [KO:K05434]
607671  TSLP; thymic stromal lymphopoietin isoform X5 [KO:K05436]
481497  IL3; interleukin-3 precursor [KO:K04736]
403790  IL5; interleukin-5 precursor [KO:K05428]
403923  CSF2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
442990  IL13; interleukin-13 precursor [KO:K05435]
404002  EPO; LOW QUALITY PROTEIN: erythropoietin [KO:K05437]
403795  GH1; somatotropin precursor [KO:K05438]
488241  PRL; prolactin precursor [KO:K05439]
100855822  THPO; thrombopoietin isoform X1 [KO:K06854]
608246  CSF3; granulocyte colony-stimulating factor [KO:K05423]
403616  LEP; leptin precursor [KO:K05424]
403985  IL6; interleukin-6 precursor [KO:K05405]
403977  IL12A; interleukin-12 subunit alpha precursor [KO:K05406]
403976  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
481110  IL23A; interleukin-23 subunit alpha [KO:K05426]
607880  IL27; interleukin-27 subunit alpha isoform X1 [KO:K22629]
485043  EBI3; interleukin-27 subunit beta isoform X1 [KO:K24476]
100302725  IL31; interleukin-31 precursor [KO:K22631]
483697  CLCF1; cardiotrophin-like cytokine factor 1 isoform X2 [KO:K05421]
483464  CNTF; ciliary neurotrophic factor [KO:K05420]
403821  CTF1; cardiotrophin-1 [KO:K05422]
489915  cardiotrophin-2-like [KO:K24382]
403449  LIF; leukemia inhibitory factor precursor [KO:K05419]
611921  OSM; oncostatin-M [KO:K05418]
403628  IL10; interleukin-10 precursor [KO:K05443]
490265  IL19; interleukin-19 [KO:K05444]
609203  IL20; interleukin-20 isoform X1 [KO:K22667]
609213  IL24; interleukin-24 isoform X1 [KO:K22668]
481153  IL22; interleukin-22 [KO:K05445]
608923  IL26; interleukin-26 [KO:K05446]
119870346  IFNL3; interferon lambda-3 [KO:K22669]
611377  IL29L; interleukin 29-like precursor [KO:K05447]
612539  IFNL1; interferon lambda-1 [KO:K05447]
474181  IFNA7; interferon alpha-1/2 precursor [KO:K05414]
442934  IFNA5; interferon alpha-3 precursor [KO:K05414]
611406  interferon alpha-1/2-like isoform X1 [KO:K05414]
100686162  interferon alpha-2-like [KO:K05414]
100682977  interferon alpha-1/2 isoform X5 [KO:K05414]
100683045  LOW QUALITY PROTEIN: interferon alpha-1/2 isoform X5 [KO:K05414]
100683567  interferon alpha-1/2-like isoform X1 [KO:K05414]
100688005  interferon alpha-1/2 [KO:K05414]
100685213  interferon alpha-1/2 [KO:K05414]
100688084  interferon alpha-1/2 isoform X1 [KO:K05414]
481558  IFNB1; interferon beta precursor [KO:K05415]
100855436  IFNK; interferon kappa [KO:K05441]
111089992  IFNE; interferon epsilon isoform X1 [KO:K05442]
403801  IFNG; interferon gamma precursor [KO:K04687]
403782  IL1A; interleukin-1 alpha [KO:K04383]
403974  IL1B; interleukin-1 beta [KO:K04519]
403660  IL1RN; interleukin-1 receptor antagonist protein precursor [KO:K05481]
611869  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
483068  IL36B; interleukin-36 beta isoform X1 [KO:K05486]
100686137  IL36G; interleukin-36 gamma isoform X1 [KO:K05487]
611873  IL1F10; interleukin-1 family member 10 [KO:K05488]
100686057  IL37; interleukin-37 [KO:K05485]
403796  IL18; interleukin-18 precursor [KO:K05482]
403810  IL33; interleukin-33 [KO:K12967]
481837  IL17A; interleukin-17A precursor [KO:K05489]
481838  IL17F; interleukin-17F isoform X2 [KO:K05494]
489193  IL17B; interleukin-17B [KO:K05490]
608988  IL17C; interleukin-17C [KO:K05491]
102156421  IL17D; interleukin-17D isoform X5 [KO:K05492]
480252  IL25; interleukin-25 [KO:K05493]
488762  IL16; pro-interleukin-16 isoform X1 [KO:K22628]
102156096  IL32; interleukin-32 isoform X1 [KO:K22632]
610536  IL34; interleukin-34 isoform X5 [KO:K22633]
611795  CSF1; macrophage colony-stimulating factor 1 isoform X4 [KO:K05453]
403922  TNF; tumor necrosis factor [KO:K03156]
607183  LTA; lymphotoxin-alpha precursor [KO:K05468]
481712  LTB; lymphotoxin-beta [KO:K03157]
611306  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
442968  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
481688  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
100174780  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
491935  EDA; ectodysplasin-A [KO:K05480]
403402  NGF; beta-nerve growth factor precursor [KO:K02582]
609418  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
100568280  TNFSF12; tumor necrosis factor ligand superfamily member 12 [KO:K05474]
485018  CD70; CD70 antigen [KO:K05470]
612608  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
403468  CD40LG; CD40 ligand [KO:K03161]
100855878  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
100855912  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
100568281  TNFSF13; tumor necrosis factor ligand superfamily member 13 [KO:K05475]
485545  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
403998  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
488596  TGFB2; transforming growth factor beta-2 proprotein isoform X3 [KO:K13376]
490796  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
484822  GDF15; growth/differentiation factor 15 [KO:K05504]
611149  GDF2; growth/differentiation factor 2 isoform X1 [KO:K05503]
481408  BMP10; bone morphogenetic protein 10 [KO:K22670]
488540  INHA; inhibin alpha chain [KO:K05500]
100855862  BMP3; bone morphogenetic protein 3 [KO:K05496]
611168  GDF10; growth/differentiation factor 10 [KO:K22674]
606826  GDF11; LOW QUALITY PROTEIN: growth/differentiation factor 11 [KO:K22679]
403433  MSTN; growth/differentiation factor 8 precursor [KO:K05497]
483245  INHBA; inhibin beta A chain [KO:K04667]
483880  INHBB; inhibin beta B chain [KO:K22687]
119870005  LOW QUALITY PROTEIN: inhibin beta B chain-like [KO:K22687]
100686938  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
477702  GDF3; growth/differentiation factor 3 [KO:K22672]
489028  NODAL; nodal homolog isoform X1 [KO:K04666]
100313495  GDF9; growth/differentiation factor 9 precursor [KO:K22673]
607422  INHBC; inhibin beta C chain [KO:K22688]
100856447  INHBE; inhibin beta E chain isoform X1 [KO:K22689]
485072  AMH; muellerian-inhibiting factor precursor [KO:K04665]
477162  BMP2; bone morphogenetic protein 2 isoform X1 [KO:K21283]
490695  BMP4; bone morphogenetic protein 4 precursor [KO:K04662]
485850  GDF5; growth/differentiation factor 5 [KO:K04664]
102152821  GDF7; LOW QUALITY PROTEIN: growth/differentiation factor 7 [KO:K20013]
100856301  BMP15; bone morphogenetic protein 15 [KO:K05498]
474944  BMP5; bone morphogenetic protein 5 [KO:K04663]
478715  BMP6; LOW QUALITY PROTEIN: bone morphogenetic protein 6 [KO:K16620]
477270  BMP7; bone morphogenetic protein 7 precursor [KO:K16621]
607768  LOW QUALITY PROTEIN: bone morphogenetic protein 8A [KO:K16622]
100855618  bone morphogenetic protein 8B isoform X2 [KO:K16622]
485600  CCR8; C-C chemokine receptor type 8 [KO:K04183]
484793  CCR9; C-C chemokine receptor type 9 [KO:K04184]
100856510  ACKR4; atypical chemokine receptor 4 [KO:K04186]
491011  CCR7; C-C chemokine receptor type 7 isoform X1 [KO:K04182]
403541  CCR4; C-C chemokine receptor type 4 [KO:K04179]
484789  CCR5; C-C chemokine receptor type 5 [KO:K04180]
448802  CCR3; C-C chemokine receptor type 3 [KO:K04178]
484790  CCR2; C-C chemokine receptor type 2 [KO:K04177]
484791  CCR1; C-C chemokine receptor type 1 [KO:K04176]
607528  CCR10; C-C chemokine receptor type 10 isoform X2 [KO:K04185]
484080  CCR6; C-C chemokine receptor type 6 [KO:K04181]
478906  CXCR1; C-X-C chemokine receptor type 2 [KO:K04175]
478905  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
491952  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
489378  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
119863891  C-X-C chemokine receptor type 4 [KO:K04189]
403964  ACKR3; atypical chemokine receptor 3 [KO:K04304]
608840  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
484792  XCR1; chemokine XC receptor 1 [KO:K04193]
485599  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
403870  IL2RA; interleukin-2 receptor subunit alpha precursor [KO:K05068]
403439  IL2RB; interleukin-2 receptor subunit beta isoform 2 precursor [KO:K05069]
403851  IL2RG; cytokine receptor common subunit gamma precursor [KO:K05070]
489957  IL4R; interleukin-4 receptor subunit alpha isoform X2 [KO:K05071]
612582  IL7R; interleukin-7 receptor subunit alpha isoform X2 [KO:K05072]
100684807  LOW QUALITY PROTEIN: interleukin-9 receptor [KO:K05073]
487141  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
608011  IL21R; interleukin-21 receptor [KO:K05075]
491709  CRLF2; cytokine receptor-like factor 2 isoform X1 [KO:K05078]
609293  IL3RA; interleukin-3 receptor subunit alpha isoform X16 [KO:K04737]
481276  CSF2RB; cytokine receptor common subunit beta [KO:K04738]
476553  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
609266  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1 [KO:K05066]
100686341  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X2 [KO:K05066]
403623  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
403622  IL13RA2; interleukin-13 receptor subunit alpha-2 precursor [KO:K05077]
484943  EPOR; erythropoietin receptor precursor [KO:K05079]
403721  GHR; growth hormone receptor precursor [KO:K05080]
479363  PRLR; prolactin receptor isoform X2 [KO:K05081]
610801  MPL; thrombopoietin receptor isoform X1 [KO:K05082]
607605  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
450207  LEPR; leptin receptor [KO:K05062]
612271  IL6R; interleukin-6 receptor subunit alpha isoform X3 [KO:K05055]
403545  IL6ST; interleukin-6 receptor subunit beta precursor [KO:K05060]
481588  IL11RA; interleukin-11 receptor subunit alpha isoform X1 [KO:K05056]
484828  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
489550  IL12RB2; interleukin-12 receptor subunit beta-2 precursor [KO:K05064]
609732  IL23R; interleukin-23 receptor [KO:K05065]
484907  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
487212  IL31RA; interleukin-31 receptor subunit alpha isoform X2 [KO:K22630]
442941  CNTFR; ciliary neurotrophic factor receptor subunit alpha precursor [KO:K05059]
449478  LIFR; leukemia inhibitory factor receptor precursor [KO:K05058]
489223  OSMR; oncostatin-M-specific receptor subunit beta isoform X1 [KO:K05057]
610823  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
478404  IL10RB; interleukin-10 receptor subunit beta isoform X2 [KO:K05135]
484002  IL20RA; interleukin-20 receptor subunit alpha isoform X2 [KO:K05136]
610961  IL20RB; interleukin-20 receptor subunit beta isoform X3 [KO:K05137]
612279  IL22RA1; interleukin-22 receptor subunit alpha-1 isoform X2 [KO:K05138]
612276  IFNLR1; interferon lambda receptor 1 [KO:K05140]
609830  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
100856468  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
100856077  IFNGR1; interferon gamma receptor 1 [KO:K05132]
487739  IFNGR2; interferon gamma receptor 2 isoform X3 [KO:K05133]
481328  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
488126  IL1RAP; interleukin-1 receptor accessory protein isoform X2 [KO:K04723]
481330  IL1R2; interleukin-1 receptor type 2 isoform X1 [KO:K04387]
611453  IL1RL2; interleukin-1 receptor-like 2 isoform X1 [KO:K05172]
610528  LOW QUALITY PROTEIN: interleukin-1 receptor-like 2 [KO:K05172]
611438  IL18R1; interleukin-18 receptor 1 isoform X2 [KO:K05173]
481327  IL18RAP; interleukin-18 receptor accessory protein isoform X3 [KO:K05174]
611442  IL1RL1; interleukin-1 receptor-like 1 [KO:K05171]
486759  IL17RA; interleukin-17 receptor A isoform X1 [KO:K05164]
610118  IL17RC; interleukin-17 receptor C isoform X2 [KO:K05166]
476587  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
484661  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
403931  CD4; T-cell surface glycoprotein CD4 precursor [KO:K06454]
489188  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
403634  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X5 [KO:K03158]
487437  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X2 [KO:K05141]
486728  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
479580  TNFRSF14; tumor necrosis factor receptor superfamily member 14 precursor [KO:K05152]
486469  FAS; tumor necrosis factor receptor superfamily member 6 isoform X2 [KO:K04390]
489632  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X1 [KO:K05160]
100688321  tumor necrosis factor receptor superfamily member 10A-like isoform X1 [KO:K04722]
609964  TNFRSF21; tumor necrosis factor receptor superfamily member 21 isoform X1 [KO:K05157]
481305  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
491071  NGFR; tumor necrosis factor receptor superfamily member 16 isoform X3 [KO:K02583]
100855848  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
483957  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
610734  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A precursor [KO:K05149]
611674  CD27; CD27 antigen isoform X1 [KO:K05144]
487438  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X2 [KO:K05145]
403469  CD40; tumor necrosis factor receptor superfamily member 5 precursor [KO:K03160]
608274  TNFRSF9; tumor necrosis factor receptor superfamily member 9 isoform X1 [KO:K05146]
489600  TNFRSF4; tumor necrosis factor receptor superfamily member 4 isoform X1 [KO:K05142]
606971  TNFRSF18; tumor necrosis factor receptor superfamily member 18 precursor [KO:K05154]
100684674  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
609580  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B isoform X1 [KO:K05150]
607785  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C isoform X1 [KO:K05151]
486042  TNFRSF19; tumor necrosis factor receptor superfamily member 19 [KO:K05155]
485200  RELT; tumor necrosis factor receptor superfamily member 19L isoform X1 [KO:K05156]
478041  RELL2; RELT-like protein 2 [KO:K26541]
479117  RELL1; RELT-like protein 1 isoform X7 [KO:K26541]
481628  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
477039  TGFBR2; TGF-beta receptor type-2 isoform X2 [KO:K04388] [EC:2.7.11.30]
477603  ACVRL1; serine/threonine-protein kinase receptor R3 isoform X2 [KO:K13594] [EC:2.7.11.30]
476140  ACVR2A; activin receptor type-2A isoform X2 [KO:K04670] [EC:2.7.11.30]
478875  BMPR2; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
485590  ACVR2B; activin receptor type-2B isoform X1 [KO:K13596] [EC:2.7.11.30]
486537  ACVR1B; activin receptor type-1B isoform X3 [KO:K13567] [EC:2.7.11.30]
488361  ACVR1C; activin receptor type-1C isoform X1 [KO:K13568] [EC:2.7.11.30]
478757  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
486506  AMHR2; LOW QUALITY PROTEIN: anti-Muellerian hormone type-2 receptor isoform X5 [KO:K04672] [EC:2.7.11.30]
489077  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
478484  BMPR1B; bone morphogenetic protein receptor type-1B [KO:K13578] [EC:2.7.11.30]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
PMID:23847622
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
PMID:21349428
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
PMID:17530315
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
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