KEGG   PATHWAY: rbb05152
Entry
rbb05152                    Pathway                                
Name
Tuberculosis - Rhinopithecus bieti (black snub-nosed monkey)
Description
Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent infections, and about 10% of latent infections develop active diseases when their immune system is impaired due to the age, other diseases such as AIDS or exposure to immunosuppressive drugs. TB is transmitted through the air and primarily attacks the lungs, then it can spread by the circulatory system to other parts of body. Once TB bacilli have entered the host by the respiratory route and infected macrophages in the lungs, they interfere with phagosomal maturation, antigen presentation, apoptosis and host immune system to establish persistent or latent infection.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
rbb05152  Tuberculosis
rbb05152

Organism
Rhinopithecus bieti (black snub-nosed monkey) [GN:rbb]
Gene
108520255  TNF; tumor necrosis factor isoform X1 [KO:K03156]
108536511  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
108515408  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
108538801  FADD; FAS-associated death domain protein [KO:K02373]
108532002  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
108532107  CASP10; caspase-10 isoform X1 [KO:K04400] [EC:3.4.22.63]
108512689  LOW QUALITY PROTEIN: caspase-3-like [KO:K02187] [EC:3.4.22.56]
108541711  BID; BH3-interacting domain death agonist [KO:K04726]
108523624  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
108530087  cytochrome c-like [KO:K08738]
108532915  cytochrome c [KO:K08738]
108535521  cytochrome c [KO:K08738]
108524009  cytochrome c [KO:K08738]
108538827  cytochrome c-like [KO:K08738]
108536287  cytochrome c-like [KO:K08738]
108524923  cytochrome c-like [KO:K08738]
108523439  cytochrome c-like [KO:K08738]
108533297  cytochrome c-like [KO:K08738]
108524269  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
108543462  APAF1; LOW QUALITY PROTEIN: apoptotic protease-activating factor 1 [KO:K02084]
108512498  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
108539069  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
108521880  AKT1; LOW QUALITY PROTEIN: RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
108542734  BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
108526412  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
108532044  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
108544005  LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit beta-like [KO:K04515] [EC:2.7.11.17]
108529387  calcium/calmodulin-dependent protein kinase type II subunit beta-like isoform X1 [KO:K04515] [EC:2.7.11.17]
108516884  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
108512486  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
108532274  IFNG; LOW QUALITY PROTEIN: interferon gamma [KO:K04687]
108522967  IFNGR1; interferon gamma receptor 1 [KO:K05132]
108536857  IFNGR2; interferon gamma receptor 2 [KO:K05133]
108532886  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
108523026  LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2-like [KO:K04447] [EC:2.7.10.2]
108527866  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
108541217  CIITA; LOW QUALITY PROTEIN: MHC class II transactivator [KO:K08060] [EC:2.7.11.1]
108533234  RFX5; DNA-binding protein RFX5 [KO:K08061]
108515646  RFXANK; DNA-binding protein RFXANK isoform X1 [KO:K08062]
108516591  RFXAP; regulatory factor X-associated protein [KO:K08063]
108528378  NFYA; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
108544257  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
108530393  NFYC; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
108540349  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
108540290  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
108540291  HLA class II histocompatibility antigen, DP beta 1 chain [KO:K06752]
108540294  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
108512973  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
108512974  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
108512982  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
108512983  HLA class II histocompatibility antigen, DQ beta 1 chain [KO:K06752]
108512984  HLA class II histocompatibility antigen, DQ alpha 1 chain [KO:K06752]
108512985  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
108519881  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
108519884  HLA class II histocompatibility antigen, DRB1-13 beta chain isoform X1 [KO:K06752]
108519885  HLA class II histocompatibility antigen, DR beta 5 chain [KO:K06752]
108532043  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
108538320  CREBBP; LOW QUALITY PROTEIN: CREB-binding protein [KO:K04498] [EC:2.3.1.48]
108528445  EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
108535116  IL10; interleukin-10 [KO:K05443]
108536390  IL10RA; interleukin-10 receptor subunit alpha isoform X1 [KO:K05134]
108536853  IL10RB; interleukin-10 receptor subunit beta isoform X1 [KO:K05135]
108533262  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
108543658  CLEC4E; C-type lectin domain family 4 member E [KO:K10059]
108521184  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma [KO:K07983]
108517053  CLEC7A; C-type lectin domain family 7 member A isoform X1 [KO:K10074]
108519844  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
108516810  tyrosine-protein kinase SYK-like [KO:K05855] [EC:2.7.10.2]
108538610  SYK; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
108542902  CARD9; caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
108541070  MALT1; LOW QUALITY PROTEIN: mucosa-associated lymphoid tissue lymphoma translocation protein 1 [KO:K07369] [EC:3.4.22.-]
108514736  BCL10; B-cell lymphoma/leukemia 10 [KO:K07368]
108536321  NOD2; nucleotide-binding oligomerization domain-containing protein 2 isoform X1 [KO:K10165]
108526904  RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
108541693  HSPA9; stress-70 protein, mitochondrial [KO:K04043]
108527810  HSPD1; LOW QUALITY PROTEIN: 60 kDa heat shock protein, mitochondrial [KO:K04077] [EC:5.6.1.7]
108525048  60 kDa heat shock protein, mitochondrial [KO:K04077] [EC:5.6.1.7]
108535226  60 kDa heat shock protein, mitochondrial [KO:K04077] [EC:5.6.1.7]
108519854  LBP; lipopolysaccharide-binding protein [KO:K05399]
108529041  TLR2; toll-like receptor 2 [KO:K10159]
108536763  TLR1; LOW QUALITY PROTEIN: toll-like receptor 1 [KO:K05398]
108536762  TLR6; toll-like receptor 6 [KO:K10169]
108530054  TLR4; toll-like receptor 4 isoform X1 [KO:K10160]
108530826  CD14; monocyte differentiation antigen CD14 [KO:K04391]
108542317  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein isoform X1 [KO:K05403]
108512239  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
108539989  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
108535063  IRAK1; LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
108512268  IRAK2; interleukin-1 receptor-associated kinase-like 2 [KO:K04731] [EC:2.7.11.1]
108535559  TRAF6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
108532817  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
108543519  RELA; transcription factor p65 [KO:K04735]
108528326  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
108528327  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
108539403  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
108539422  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
108523695  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
108536070  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
108537794  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
108521141  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
108517508  mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
108539959  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
108529326  IL6; interleukin-6 isoform X1 [KO:K05405]
108514790  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
108537933  IL12B; interleukin-12 subunit beta [KO:K05425]
108536445  IL18; interleukin-18 isoform X1 [KO:K05482]
108516020  IL23A; interleukin-23 subunit alpha [KO:K05426]
108541808  IL1A; interleukin-1 alpha [KO:K04383]
108541809  IL1B; interleukin-1 beta [KO:K04519]
108525077  CEBPB; CCAAT/enhancer-binding protein beta [KO:K10048]
108517251  CEBPG; CCAAT/enhancer-binding protein gamma [KO:K10049]
108522342  TLR9; toll-like receptor 9 isoform X1 [KO:K10161]
108525122  interferon alpha-10 [KO:K05414]
108538560  interferon alpha-4-like [KO:K05414]
108525752  LOW QUALITY PROTEIN: interferon alpha-21-like [KO:K05414]
108536968  IFNA8; LOW QUALITY PROTEIN: interferon alpha-8 [KO:K05414]
108536996  interferon alpha-14 [KO:K05414]
108537115  LOW QUALITY PROTEIN: interferon alpha-6-like [KO:K05414]
108537124  IFNA6; interferon alpha-6 [KO:K05414]
108538565  IFNB1; interferon beta [KO:K05415]
108534530  CD209 antigen isoform X1 [KO:K06563]
108534603  CD209 antigen-like protein 2 isoform X1 [KO:K06563]
108528604  ARHGEF12; rho guanine nucleotide exchange factor 12 [KO:K07532]
108526989  RHOA; transforming protein RhoA [KO:K04513]
108531328  LSP1; lymphocyte-specific protein 1 isoform X1 [KO:K14957]
108535666  PLK3; serine/threonine-protein kinase PLK3 [KO:K08862] [EC:2.7.11.21]
108512967  KSR1; kinase suppressor of Ras 1 isoform X1 [KO:K14958]
108517986  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
108536158  TGFB1; transforming growth factor beta-1 isoform X1 [KO:K13375]
108528282  TGFB2; transforming growth factor beta-2 isoform X1 [KO:K13376]
108534939  TGFB3; transforming growth factor beta-3 [KO:K13377]
108524407  25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [KO:K07438] [EC:1.14.15.18]
108515961  VDR; vitamin D3 receptor isoform X1 [KO:K08539]
108517622  CAMP; cathelicidin antimicrobial peptide [KO:K13916]
108534593  C3; complement C3 [KO:K03990]
108530296  complement receptor type 1-like [KO:K04011]
108539535  complement component receptor 1-like protein [KO:K04011]
108539534  CR1; complement receptor type 1 [KO:K04011]
108527840  ITGAX; integrin alpha-X isoform X1 [KO:K06462]
108539787  ITGB2; LOW QUALITY PROTEIN: integrin beta-2 [KO:K06464]
108528119  ITGAM; integrin alpha-M isoform X1 [KO:K06461]
108527698  PLA2R1; secretory phospholipase A2 receptor isoform X1 [KO:K06560]
108527752  MRC1; macrophage mannose receptor 1 [KO:K06560]
108536289  MRC2; C-type mannose receptor 2 isoform X1 [KO:K06560]
108537441  SPHK1; sphingosine kinase 1 isoform X1 [KO:K04718] [EC:2.7.1.91]
108523630  SPHK2; sphingosine kinase 2 isoform X1 [KO:K04718] [EC:2.7.1.91]
108536001  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
108512653  CALM2; calmodulin [KO:K02183]
108514692  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
108529886  CALML3; calmodulin-like protein 3 [KO:K02183]
108529898  CALML5; calmodulin-like protein 5 [KO:K02183]
108531068  CALM3; calmodulin isoform X1 [KO:K02183]
108533995  calmodulin [KO:K02183]
108535906  CALM1; calmodulin [KO:K02183]
108537659  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
108521254  RAB5A; ras-related protein Rab-5A [KO:K07887]
108516054  RAB5B; ras-related protein Rab-5B [KO:K07888]
108518346  RAB5C; ras-related protein Rab-5C [KO:K07889]
108527188  EEA1; LOW QUALITY PROTEIN: early endosome antigen 1 [KO:K12478]
108537507  RAB7A; ras-related protein Rab-7a [KO:K07897]
108531312  CTSD; cathepsin D [KO:K01379] [EC:3.4.23.5]
108518675  TCIRG1; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
108534827  ATP6V0A4; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
108518317  ATP6V0A1; V-type proton ATPase 116 kDa subunit a [KO:K02154]
108540639  ATP6V0A2; V-type proton ATPase 116 kDa subunit a [KO:K02154]
108515413  ATP6V0D1; V-type proton ATPase subunit d 1 isoform X1 [KO:K02146]
108523206  ATP6V0D2; V-type proton ATPase subunit d 2 [KO:K02146]
108517399  ATP6V1H; V-type proton ATPase subunit H isoform X1 [KO:K02144]
108518773  ATP6AP1; V-type proton ATPase subunit S1 [KO:K03662]
108524797  LOW QUALITY PROTEIN: uncharacterized protein LOC108524797 [KO:K02155]
108533491  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
108519445  ATP6V0C; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
108535688  ATP6V0B; V-type proton ATPase 21 kDa proteolipid subunit isoform X1 [KO:K03661]
108521829  LAMP1; lysosome-associated membrane glycoprotein 1 [KO:K06528]
108522825  LAMP2; LOW QUALITY PROTEIN: lysosome-associated membrane glycoprotein 2 [KO:K06528]
108542795  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [KO:K04348] [EC:3.1.3.16]
108516875  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
108540785  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
108537161  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
108523678  CORO1A; coronin-1A [KO:K13882]
108522153  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
108511997  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
108512001  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 isoform X1 [KO:K06856]
108520828  uncharacterized protein LOC108520828 [KO:K06856]
108519975  uncharacterized protein LOC108519975 [KO:K06856]
108519976  LOW QUALITY PROTEIN: uncharacterized protein LOC108519976 [KO:K06856]
108519983  uncharacterized protein LOC108519983 [KO:K06856]
108519992  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
108524775  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
108538696  high affinity immunoglobulin gamma Fc receptor I isoform X1 [KO:K06498]
108542586  FCGR2A; low affinity immunoglobulin gamma Fc region receptor II-a isoform X1 [KO:K06472]
108542588  FCGR2B; LOW QUALITY PROTEIN: low affinity immunoglobulin gamma Fc region receptor II-b [KO:K12560]
108542585  LOW QUALITY PROTEIN: low affinity immunoglobulin gamma Fc region receptor III-like [KO:K06463]
Compound
C00076  Calcium cation
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C01561  Calcidiol
C01673  Calcitriol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C06124  Sphingosine 1-phosphate
C19190  Trehalose-6,6'-dibehenate
C21790  Mycobacterial trehalose dimycolate
G13101  Lipomannan
G13105  Triacylated phosphatidyl-myo-inositol pentamannoside
G13106  Triacylated phosphatidyl-myo-inositol hexamannoside
G13108  Triacylated phosphatidyl-myo-inositol dimannoside
G13109  Tetraacylated phosphatidyl-myo-inositol dimannoside
G13112  Tetraacylated phosphatidyl-myo-inositol hexamannoside
G13113  Tetraacylated phosphatidyl-myo-inositol pentamannoside
G13114  Lipoarabinomannan
G13115  Mannose-capped lipoarabinomannan
Reference
PMID:21274449
  Authors
Saiga H, Shimada Y, Takeda K
  Title
Innate immune effectors in mycobacterial infection.
  Journal
Clin Dev Immunol 2011:347594 (2011)
DOI:10.1155/2011/347594
Reference
PMID:20415982
  Authors
Dheda K, Schwander SK, Zhu B, van Zyl-Smit RN, Zhang Y
  Title
The immunology of tuberculosis: from bench to bedside.
  Journal
Respirology 15:433-50 (2010)
DOI:10.1111/j.1440-1843.2010.01739.x
Reference
PMID:11932234
  Authors
van Crevel R, Ottenhoff TH, van der Meer JW
  Title
Innate immunity to Mycobacterium tuberculosis.
  Journal
Clin Microbiol Rev 15:294-309 (2002)
DOI:10.1128/CMR.15.2.294-309.2002
Reference
PMID:18288961
  Authors
Torrelles JB, Azad AK, Henning LN, Carlson TK, Schlesinger LS
  Title
Role of C-type lectins in mycobacterial infections.
  Journal
Curr Drug Targets 9:102-12 (2008)
DOI:10.2174/138945008783502467
Reference
PMID:17359235
  Authors
Jo EK, Yang CS, Choi CH, Harding CV
  Title
Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors.
  Journal
Cell Microbiol 9:1087-98 (2007)
DOI:10.1111/j.1462-5822.2007.00914.x
Reference
PMID:21274433
  Authors
Marakalala MJ, Graham LM, Brown GD
  Title
The role of Syk/CARD9-coupled C-type lectin receptors in immunity to Mycobacterium tuberculosis infections.
  Journal
Clin Dev Immunol 2010:567571 (2010)
DOI:10.1155/2010/567571
Reference
PMID:15083155
  Authors
Koul A, Herget T, Klebl B, Ullrich A
  Title
Interplay between mycobacteria and host signalling pathways.
  Journal
Nat Rev Microbiol 2:189-202 (2004)
DOI:10.1038/nrmicro840
Reference
PMID:20199890
  Authors
Torrelles JB, Schlesinger LS
  Title
Diversity in Mycobacterium tuberculosis mannosylated cell wall determinants impacts adaptation to the host.
  Journal
Tuberculosis (Edinb) 90:84-93 (2010)
DOI:10.1016/j.tube.2010.02.003
Reference
PMID:15228522
  Authors
Briken V, Porcelli SA, Besra GS, Kremer L
  Title
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response.
  Journal
Mol Microbiol 53:391-403 (2004)
DOI:10.1111/j.1365-2958.2004.04183.x
Reference
PMID:19563525
  Authors
Baena A, Porcelli SA
  Title
Evasion and subversion of antigen presentation by Mycobacterium tuberculosis.
  Journal
Tissue Antigens 74:189-204 (2009)
DOI:10.1111/j.1399-0039.2009.01301.x
Reference
PMID:19369951
  Authors
Flannagan RS, Cosio G, Grinstein S
  Title
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies.
  Journal
Nat Rev Microbiol 7:355-66 (2009)
DOI:10.1038/nrmicro2128
Reference
PMID:18541216
  Authors
Pieters J
  Title
Mycobacterium tuberculosis and the macrophage: maintaining a balance.
  Journal
Cell Host Microbe 3:399-407 (2008)
DOI:10.1016/j.chom.2008.05.006
Reference
PMID:19634703
  Authors
Scherr N, Jayachandran R, Mueller P, Pieters J
  Title
Interference of Mycobacterium tuberculosis with macrophage responses.
  Journal
Indian J Exp Biol 47:401-6 (2009)
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:17785780
  Authors
Rothfuchs AG, Bafica A, Feng CG, Egen JG, Williams DL, Brown GD, Sher A
  Title
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells.
  Journal
J Immunol 179:3463-71 (2007)
DOI:10.4049/jimmunol.179.6.3463
Reference
PMID:18407066
  Authors
Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, Springer B, Timmins GS, Sander P, Deretic V
  Title
Mycobacterium tuberculosis prevents inflammasome activation.
  Journal
Cell Host Microbe 3:224-32 (2008)
DOI:10.1016/j.chom.2008.03.003
Reference
PMID:11378475
  Authors
Shtrichman R, Samuel CE
  Title
The role of gamma interferon in antimicrobial immunity.
  Journal
Curr Opin Microbiol 4:251-9 (2001)
DOI:10.1016/S1369-5274(00)00199-5
Related
pathway
rbb04010  MAPK signaling pathway
rbb04210  Apoptosis
rbb04612  Antigen processing and presentation
rbb04620  Toll-like receptor signaling pathway
rbb04621  NOD-like receptor signaling pathway
rbb04630  JAK-STAT signaling pathway
KO pathway
ko05152   
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