KEGG   PATHWAY: loc05132
Entry
loc05132                    Pathway                                
Name
Salmonella infection - Lepisosteus oculatus (spotted gar)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
loc05132  Salmonella infection
loc05132

Organism
Lepisosteus oculatus (spotted gar) [GN:loc]
Gene
102697431  podxl; podocalyxin isoform X1 [KO:K06817]
102683459  ptprc; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
102696266  rab5a; ras-related protein Rab-5A [KO:K07887]
102696857  ras-related protein Rab-5B-like [KO:K07888]
102695880  rab5c; ras-related protein Rab-5C [KO:K07889]
102689720  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
102697663  ras-related protein Rab-7a-like [KO:K07897]
102689033  ras-related protein Rab-7a-like isoform X1 [KO:K07897]
102698928  ras-related protein Rab-7a-like isoform X1 [KO:K07897]
102699139  rab7a; ras-related protein Rab-7a [KO:K07897]
102685383  rab7b; ras-related protein Rab-7b isoform X2 [KO:K07898]
102693574  plekhm1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
102698587  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
102689416  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
102686954  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
102683412  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
102684799  vps39; vam6/Vps39-like protein isoform X1 [KO:K20183]
102685003  vps41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
102698344  dync1h1; cytoplasmic dynein 1 heavy chain 1 isoform X3 [KO:K10413]
102694862  dync2h1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
102695544  dync1i1; cytoplasmic dynein 1 intermediate chain 1 isoform X4 [KO:K10415]
102690281  dync1i2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
102695474  dync1li1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
102684034  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
102690837  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
102687308  dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
102690361  dynein light chain 2, cytoplasmic [KO:K10418]
102688613  dynlrb1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
102684427  dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
102697203  dynlt1; dynein light chain Tctex-type 1 isoform X1 [KO:K10420]
102692303  dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
102692341  dynein light chain Tctex-type 1-like [KO:K10420]
102685511  dctn1; dynactin subunit 1 isoform X1 [KO:K04648]
102693409  dctn2; dynactin subunit 2 isoform X4 [KO:K10424]
102692631  dctn3; dynactin subunit 3 [KO:K10425]
102696184  dctn4; dynactin subunit 4 isoform X1 [KO:K10426]
102683464  dctn5; dynactin subunit 5 [KO:K10427]
102694800  dctn6; dynactin subunit 6 [KO:K10428]
102689968  beta-centractin [KO:K16575]
102693886  alpha-centractin isoform X2 [KO:K16575]
102694218  actr10; actin-related protein 10 [KO:K16576]
102687936  tuba3e; tubulin alpha-3E chain [KO:K07374]
102687820  tubulin alpha-8 chain isoform X1 [KO:K07374]
102684903  tubulin alpha-3 chain-like [KO:K07374]
102694561  tubulin alpha chain-like [KO:K07374]
102694763  tubulin alpha chain isoform X1 [KO:K07374]
102695089  tubulin alpha chain-like [KO:K07374]
102688152  tubulin alpha chain [KO:K07374]
102687274  tubulin alpha-1C chain [KO:K07374]
102698167  tubulin beta chain isoform X1 [KO:K07375]
102688593  tubulin beta-2B chain [KO:K07375]
102686982  tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
102697845  tubulin beta chain-like [KO:K07375]
102687056  tubb3; tubulin beta-3 chain [KO:K07375]
102685124  tubulin beta-4B chain [KO:K07375]
102697233  tubulin beta-5 chain isoform X1 [KO:K07375]
102687770  fyco1; FYVE and coiled-coil domain-containing protein 1 isoform X1 [KO:K21954]
102691192  ADP-ribosylation factor-like protein 8A [KO:K07955]
102694210  arl8b; ADP-ribosylation factor-like protein 8B [KO:K07955]
102687929  plekhm2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
102683648  kif5a; kinesin heavy chain isoform 5A isoform X1 [KO:K10396]
102699032  kif5b; kinesin-1 heavy chain [KO:K10396]
102686225  kif5c; kinesin heavy chain isoform 5C [KO:K10396]
102683298  kinesin light chain 1-like [KO:K10407]
102690498  klc4; kinesin light chain 4 isoform X2 [KO:K10407]
102697228  klc1; kinesin light chain 1 [KO:K10407]
102685837  klc2; kinesin light chain 2 [KO:K10407]
102696425  acbd3; Golgi resident protein GCP60 isoform X1 [KO:K23935]
102686749  transforming protein RhoA-like [KO:K04513]
102689455  rhoc; rho-related GTP-binding protein RhoC [KO:K04513]
102682211  rho-related GTP-binding protein RhoA-C [KO:K04513]
102695238  m6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
102682595  rab9a; ras-related protein Rab-9A [KO:K07899]
102696887  ras-related protein Rab-9B-like [KO:K07900]
102690201  rab9b; ras-related protein Rab-9B [KO:K07900]
102689743  gcc2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
102687042  pfn2; profilin-2 isoform X1 [KO:K05759]
102696122  pfn3; profilin-3 [KO:K05759]
102696490  pfn4; profilin-4 [KO:K05759]
102695708  flna; filamin-A isoform X7 [KO:K04437]
102693158  exoc7; exocyst complex component 7 isoform X11 [KO:K07195]
102694808  exoc5; exocyst complex component 5 [KO:K19984]
102687021  exoc4; exocyst complex component 4 isoform X2 [KO:K06111]
102690546  exoc2; exocyst complex component 2 [KO:K17637]
102690746  rala; ras-related protein Ral-A [KO:K07834]
102690749  actg1; actin, cytoplasmic 2 [KO:K05692]
102696204  actb; actin, cytoplasmic 1 [KO:K05692]
102691870  anxa2; annexin A2 [KO:K17092]
102683316  rhoj; rho-related GTP-binding protein RhoJ [KO:K07864]
102686568  arhgef26; rho guanine nucleotide exchange factor 26 isoform X1 [KO:K13744]
102682154  rhog; rho-related GTP-binding protein RhoG [KO:K07863]
102690743  rho-related GTP-binding protein RhoG-like [KO:K07863]
102699156  elmo1; engulfment and cell motility protein 1 isoform X3 [KO:K12366]
102695494  elmo2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
102688837  rock2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
102682260  myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
102688760  myl5; myosin light chain 5 [KO:K12753]
102697662  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
102694319  myosin regulatory light polypeptide 9 [KO:K12755]
102688000  myosin regulatory light chain 2B, cardiac muscle isoform [KO:K12756]
102691547  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
102690979  myosin regulatory light chain 2, skeletal muscle isoform-like [KO:K12758]
102695176  FH1/FH2 domain-containing protein 1-like isoform X1 [KO:K23938]
102683416  cdc42; cell division control protein 42 homolog isoform X2 [KO:K04393]
102698253  cell division control protein 42 homolog [KO:K04393]
102696469  rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
102684224  nckap1; nck-associated protein 1 isoform X3 [KO:K05750]
102690061  nckap1l; nck-associated protein 1-like [KO:K05750]
102693845  cyfip1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
102694547  cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X2 [KO:K05749]
102696652  abi1; abl interactor 1 isoform X6 [KO:K23649]
102692606  brk1; protein BRICK1 [KO:K05752]
102683643  wasf3; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
102689998  wiskott-Aldrich syndrome protein family member 3-like isoform X2 [KO:K06083]
102687047  actr2; actin-related protein 2 isoform X2 [KO:K17260]
102691032  actr3; actin-related protein 3 [KO:K18584]
102684217  actr3b; actin-related protein 3B isoform X1 [KO:K18584]
102694828  actin-related protein 2/3 complex subunit 1B-like [KO:K05757]
102695161  actin-related protein 2/3 complex subunit 1A [KO:K05757]
102684806  actin-related protein 2/3 complex subunit 1A-like [KO:K05757]
102697902  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
102694512  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
102691400  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
102689021  arpc5l; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
102685870  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
102692188  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
102691808  pak3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
102691586  myo6; unconventional myosin-VI isoform X1 [KO:K10358]
102691786  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
102685070  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
102688673  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
102695429  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
102699081  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like isoform X1 [KO:K21289] [EC:2.7.1.153]
102689190  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X3 [KO:K21289] [EC:2.7.1.153]
102687883  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2 [KO:K00923] [EC:2.7.1.154]
102689643  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
102690896  cyth3; cytohesin-3 [KO:K18441]
102689330  cyth1; cytohesin-1 isoform X1 [KO:K18441]
102692357  cytohesin-3-like isoform X1 [KO:K18441]
102695730  arf6; ADP-ribosylation factor 6 [KO:K07941]
102695940  ADP-ribosylation factor 1-like [KO:K07937]
102698146  arf1; ADP-ribosylation factor 1 [KO:K07937]
102693672  snx18; sorting nexin-18 [KO:K17923]
102697932  snx33; sorting nexin-33 [KO:K17923]
102694785  snx9; sorting nexin-9 isoform X1 [KO:K17923]
102690945  wasl; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
102683927  dnm2; dynamin-2 isoform X5 [KO:K23484] [EC:3.6.5.5]
102689191  toll-like receptor 1 [KO:K10169]
102684141  toll-like receptor 1 [KO:K10169]
107077084  tlr2; toll-like receptor 2 [KO:K10159]
102687114  toll-like receptor 2 type-2 isoform X2 [KO:K10159]
102688338  tirap; toll/interleukin-1 receptor domain-containing adapter protein isoform X1 [KO:K05403]
102684939  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
102693850  tlr4; LOW QUALITY PROTEIN: toll-like receptor 4 [KO:K10160]
102693268  tlr5; toll-like receptor 5 isoform X1 [KO:K10168]
102686134  toll-like receptor 9 [KO:K10161]
102698319  irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
102693125  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
102684182  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
102693991  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
102694529  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
102688534  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [KO:K12793]
102682818  NF-kappa-B essential modulator-like isoform X1 [KO:K07210]
102691336  chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
102690045  ikbkb; LOW QUALITY PROTEIN: inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
102689470  nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
102693746  nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
102697236  nod1; nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
102698061  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
102697884  hsp90aa1; heat shock protein HSP 90-alpha isoform X3 [KO:K04079]
102693534  heat shock protein HSP 90-alpha [KO:K04079]
102682439  hsp90b1; endoplasmin isoform X1 [KO:K09487]
102695929  ripk2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
102696931  cse1l; exportin-2 isoform X1 [KO:K18423]
102695642  kpna1; importin subunit alpha-5 [KO:K23940]
102684278  kpna4; importin subunit alpha-3 [KO:K23583]
102683000  kpna3; importin subunit alpha-4 [KO:K23583]
102691466  rps3; 40S ribosomal protein S3 [KO:K02985]
102697398  hras; GTPase HRas [KO:K02833]
102692545  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
102691532  map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
102686784  map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
102683764  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
102691753  map2k3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
102692628  map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
102698741  mitogen-activated protein kinase 14A isoform X2 [KO:K04441] [EC:2.7.11.24]
102695970  mitogen-activated protein kinase 13-like [KO:K04441] [EC:2.7.11.24]
102695733  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
102695926  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
102685390  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
102683325  map2k4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
102697033  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X3 [KO:K04431] [EC:2.7.12.2]
102687878  mapk10; mitogen-activated protein kinase 10 isoform X4 [KO:K04440] [EC:2.7.11.24]
102692400  mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
102691138  mitogen-activated protein kinase 9 isoform X4 [KO:K04440] [EC:2.7.11.24]
102690879  fos; proto-oncogene c-Fos [KO:K04379]
102691085  proto-oncogene c-Fos-like isoform X1 [KO:K04379]
102693762  jun; transcription factor AP-1 [KO:K04448]
102689161  transcription factor AP-1-like [KO:K04448]
107078662  il6; interleukin-6 [KO:K05405]
107077132  interleukin-8-like [KO:K10030]
107077137  interleukin-8-like [KO:K10030]
107077138  interleukin-8-like isoform X1 [KO:K10030]
102689183  C-X-C motif chemokine 10-like [KO:K10030]
102684715  interleukin-8-like [KO:K10030]
102698963  ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
102694215  tcf7; transcription factor 7 isoform X1 [KO:K02620]
102692120  tcf7l1; transcription factor 7-like 1 isoform X1 [KO:K04490]
102691677  tcf7l2; transcription factor 7-like 2 isoform X12 [KO:K04491]
102686059  lef1; lymphoid enhancer-binding factor 1 isoform X5 [KO:K04492]
102684410  myc; myc proto-oncogene protein [KO:K04377]
102695072  pkn1; serine/threonine-protein kinase N1 [KO:K06071] [EC:2.7.11.13]
102699010  fbxo22; F-box only protein 22 isoform X1 [KO:K10302]
102694012  skp1; S-phase kinase-associated protein 1 [KO:K03094]
107079892  TNF receptor-associated factor 1-like isoform X1 [KO:K03173] [EC:2.3.2.27]
102693526  traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
102695888  TNF receptor-associated factor 2-like isoform X2 [KO:K03173] [EC:2.3.2.27]
102691572  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
102688292  birc2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
102691146  ripk1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
102697075  gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
102695414  tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
107077552  tumor necrosis factor ligand superfamily member 10-like [KO:K04721]
102683981  tumor necrosis factor receptor superfamily member 10B-like isoform X1 [KO:K04722]
102690370  fadd; FAS-associated death domain protein [KO:K02373]
102697635  caspase-8-like [KO:K04398] [EC:3.4.22.61]
102697443  casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
102697829  caspase-8-like [KO:K04398] [EC:3.4.22.61]
102689963  bax; apoptosis regulator BAX [KO:K02159]
102683790  bak1; bcl-2 homologous antagonist/killer [KO:K14021]
102685547  cytochrome c [KO:K08738]
102684940  bcl2; apoptosis regulator Bcl-2 [KO:K02161]
102691196  caspase-3-like [KO:K02187] [EC:3.4.22.56]
102693931  caspase-7-like [KO:K04397] [EC:3.4.22.60]
102691279  casp7; caspase-7 isoform X2 [KO:K04397] [EC:3.4.22.60]
102682621  rhob; rho-related GTP-binding protein RhoB [KO:K07856]
102690872  rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
102690433  akt3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102684446  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
102691207  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
102687595  mlkl; mixed lineage kinase domain-like protein isoform X1 [KO:K08849] [EC:2.7.11.1]
102692095  txn2; thioredoxin, mitochondrial [KO:K03671]
102685515  txn; thioredoxin [KO:K03671]
102684700  baculoviral IAP repeat-containing protein 1b-like [KO:K12807]
107079461  baculoviral IAP repeat-containing protein 1-like isoform X1 [KO:K12807]
102686781  baculoviral IAP repeat-containing protein 1e-like [KO:K12807]
102696211  nlrc4; NLR family CARD domain-containing protein 4 isoform X1 [KO:K12805]
102686039  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
102686244  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
102696999  casp1; caspase-1 [KO:K01370] [EC:3.4.22.36]
102688855  caspase-13-like [KO:K01370] [EC:3.4.22.36]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
loc04010  MAPK signaling pathway
loc04210  Apoptosis
loc04217  Necroptosis
loc04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
LinkDB

DBGET integrated database retrieval system